Lorazepam combined with Methadone Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Multiple Drug Overdose Accidental Death 8/15/2004 47 Male 2/28/2006 Physician United States
Primary
Secondary
Paralysis Hospitalization 3/1/2006 53 Male 4/6/2006 Physician Spain
Primary
Concomitant
Blood Pressure Increased Other Serious 2/1/2006 82 Male 4/10/2006 Physician United States
Primary
Concomitant
Somnolence Life Threatening 12/17/2005 47 Male 150 lb 5/10/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Vomiting Death Female 5/19/2006
Primary
Secondary
Vision Blurred 35 Female 5/30/2006 Consumer United States
Primary
Concomitant
Overdose Death 5/26/2006 Belgium
Primary
Secondary
Vision Blurred Other Serious 2/1/2006 70 Female 135 lb 4/20/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/16/2006 30 Male 6/13/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 6/1/2006 Female 6/27/2006 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 20 Female 95 lb 6/23/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 2/28/2006 54 Female 134 lb 7/10/2006 Physician Denmark
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 6/1/2006 Female 8/16/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/20/2006 61 Female 108 lb 8/18/2006 Consumer United States
Primary
Secondary
Concomitant
Overdose Hospitalization 4/1/2006 Female 8/16/2006 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2005 Male 7/19/2006 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 42 Male 8/24/2006 United States
Primary
Concomitant
Pain In Extremity Other Serious 6/1/2006 Female 9/13/2006 Consumer United States
Primary
Concomitant
Bronchitis Hospitalization 10/1/2006 54 Female 190 lb 10/17/2006 Physician United States
Primary
Concomitant
Bronchitis Hospitalization 10/1/2006 54 Female 190 lb 11/2/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 33 Female 11/13/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Paralysis Other Serious 6/1/2006 47 Female 139 lb 12/29/2006 Physician United States
Primary
Concomitant
Tooth Loss Hospitalization 12/1/2005 Female 2/22/2007 Consumer United States
Primary
Secondary
Concomitant
Akathisia Disability 43 Female 8/17/2006 Physician United States
Primary
Concomitant
Photopsia Other Serious 3/1/2007 Female 165 lb 3/30/2007 Consumer United States
Primary
Concomitant
Sudden Death Death 3/3/2007 20 Male 4/19/2007 Switzerland
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 2/5/2007 39 Female 178 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 1/22/2006 66 Female 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 6/11/2006 43 Male 6/6/2007 Other Health Professional United States
Primary
Concomitant
Feeling Abnormal Other Serious 4/1/2007 Female 146 lb 6/8/2007 Consumer United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 23 Male 6/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2003 26 6/14/2007 United States
Primary
Secondary
Vomiting Hospitalization Female 6/15/2007 Physician United States
Primary
Secondary
Concomitant
Substance Abuse Death 3/13/2006 26 Male 230 lb 5/24/2007 Physician United States
Primary
Secondary
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 6/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 6/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria 4/10/2007 29 Female 151 lb 4/10/2007 United States
Primary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 6/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 6/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 4/1/2007 Female 146 lb 7/23/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 7/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/16/2007 15 Female 88 lb 8/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 7/28/2007 21 Male 8/10/2007 Pharmacist United States
Primary
Secondary
Pancreatitis Required Intervention 7/28/2007 21 Male 8/21/2007 United States
Primary
Concomitant
Drug Tolerance Hospitalization 18 Male 8/27/2007
Primary
Secondary
Concomitant
Necrotising Fasciitis Staphylococcal Hospitalization 30 Female 8/28/2007 Physician United States
Primary
Concomitant
Vomiting Life Threatening 54 Male 9/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 23 Male 9/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 23 Male 10/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 142 lb 10/19/2007 Consumer United States
Primary
Concomitant
Vertebroplasty Other Serious 10/18/2007 65 Female 10/31/2007 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 11/13/2007 39 Male 12/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis 8/23/2007 Female 155 lb 12/15/2007 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Arrest Death 58 Female 1/21/2008 Physician United States
Primary
Secondary
Neonatal Disorder Other Serious 1/1/1994 Male 1/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 2/4/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 58 Female 1/25/2008 Physician United States
Primary
Secondary
Respiratory Arrest Death 58 Female 2/1/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 58 Female 2/13/2008 United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 58 Female 2/13/2008 Physician United States
Primary
Secondary
Varicose Vein 1/1/1999 51 Female 2/22/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 20 Female 3/12/2008 Physician United States
Primary
Secondary
Concomitant
Intestinal Perforation Congenital Anomaly 11/9/1994 Male 9 lb 2/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Death 3/3/2007 20 Male 4/3/2008 Switzerland
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2007 Female 135 lb 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2007 Female 135 lb 4/29/2008 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 54 Male 4/30/2008
Primary
Secondary
Concomitant
Multiple Drug Overdose Accidental Hospitalization 11/15/2007 Female 5/7/2008 Other Health Professional Germany
Primary
Secondary
Mucosal Inflammation Hospitalization 5/6/2008 58 Male 5/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/6/2008 58 Male 5/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 3/1/1999 23 Female 6/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/19/2008 Male 6/4/2008 Other Health Professional Germany
Primary
Secondary
Injection Site Urticaria 3/29/2008 Male 185 lb 6/12/2008 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 10/5/2007 49 Male 6/23/2008 Pharmacist United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 4/15/2008 58 Male 7/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/11/2008 Male 8/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Priapism 7/2/2008 1 Male 13 lb 8/11/2008 Pharmacist United States
Primary
Concomitant
Troponin Increased Hospitalization 1/1/2006 58 Female 8/18/2008 Physician United States
Primary
Secondary
Pruritus 4/22/2008 Male 8/27/2008 Physician United States
Primary
Concomitant
Viral Infection 9/1/2007 29 Female 9/12/2008 Physician United States
Primary
Concomitant
Treatment Failure Other Serious 24 Female 9/11/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 56 Male 9/22/2008 Physician United States
Primary
Secondary
Concomitant
Presyncope Other Serious 8/16/2008 Male 12/5/2008 Other Health Professional Japan
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2003 64 Female 150 lb 1/21/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/30/2008 Female 108 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Restless Legs Syndrome Hospitalization 10/29/2008 42 Female 2/27/2009 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Restless Legs Syndrome Hospitalization 10/29/2008 Female 3/4/2009 Switzerland
Primary
Secondary
Concomitant
Incorrect Dose Administered 2/22/2009 Male 182 lb 3/14/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 4/8/2009 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 7/19/2001 45 Female 242 lb 4/21/2009 United States
Primary
Concomitant
Lipoma Other Serious 2/1/2009 61 Male 208 lb 4/24/2009 Physician United States
Primary
Concomitant
Application Site Discolouration 5/6/2009 1 Female 13 lb 5/6/2009 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/5/2009 Female 5/8/2009 Physician United States
Primary
Concomitant
Drug Ineffective Female 155 lb 6/12/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 4/1/2004 73 Female 217 lb 6/25/2009 United States
Primary
Concomitant
Pancreatitis Acute Other Serious 1/5/2002 27 Female 187 lb 7/2/2009 United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 140 lb 7/16/2009 United States
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 42 Male 222 lb 7/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/25/2002 43 Male 257 lb 7/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/10/2001 40 Female 179 lb 7/27/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious Female 191 lb 9/3/2009 United States
Primary
Secondary
Concomitant
Death Death 9/4/2009 Physician United States
Primary
Secondary
Upper Limb Fracture Other Serious 12/1/2003 65 Female 190 lb 9/14/2009 United States
Primary
Concomitant
Wound Dehiscence Hospitalization 7/19/2001 45 Female 189 lb 9/22/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 10/1/2005 55 Male 229 lb 9/23/2009 United States
Primary
Concomitant
Temporomandibular Joint Syndrome Required Intervention 9/15/2009 17 Male 161 lb 10/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 25 Male 10/23/2009 Physician United States
Primary
Secondary
Wound Infection Staphylococcal Required Intervention 9/15/2009 17 Male 161 lb 10/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/14/2003 Female 195 lb 11/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 23 Female 1/20/2010 United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Death 24 Female 1/20/2010 United States
Primary
Secondary
Concomitant
Respiratory Arrest Death 26 Male 1/20/2010 United States
Primary
Secondary
Concomitant
Completed Suicide Death 39 Male 1/18/2010 United States
Primary
Secondary
Concomitant
Paranoid Personality Disorder Other Serious 7/6/2004 44 Female 254 lb 2/9/2010 United States
Primary
Concomitant
Drug Withdrawal Syndrome Hospitalization 1/19/2010 Male 2/10/2010 Physician
Primary
Secondary
Concomitant
Pulmonary Oedema Death 25 Male 2/16/2010 Other Health Professional United States
Primary
Secondary
Vision Blurred Other Serious 1/1/2002 Female 195 lb 2/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia 12/1/2008 202 lb 2/16/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death Male 2/23/2010 United States
Primary
Secondary
Paranoid Personality Disorder Other Serious 1/1/2007 47 Female 254 lb 3/5/2010 United States
Primary
Concomitant
Tooth Infection Other Serious 12/1/2006 Female 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Scar Other Serious 1/1/2003 Male 3/22/2010 Physician United States
Primary
Concomitant
Substance Abuse Death 25 Male 3/15/2010 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death Male 185 lb 3/18/2010 Consumer United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2010 65 Male 4/6/2010 Physician
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 3 Female 4/6/2010
Primary
Secondary
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 12/1/2006 43 Female 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Superior Vena Caval Occlusion Other Serious 1/1/2003 59 Male 4/9/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2002 73 Female 144 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 3/21/2010 40 Female 4/13/2010 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 12/13/1994 34 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/16/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/20/2010 United States
Primary
Concomitant
Superior Vena Caval Occlusion Other Serious 1/1/2003 59 Male 4/20/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 4/14/2005 52 Male 150 lb 4/27/2010 Physician United States
Primary
Secondary
Concomitant
Insomnia Hospitalization 1/24/2010 49 Female 4/30/2010 Other Health Professional Italy
Primary
Concomitant
Tendon Disorder Other Serious 1/1/2003 59 Male 5/5/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 5/10/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2006 59 Male 177 lb 5/12/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2006 59 Male 177 lb 6/21/2010 Lawyer United States
Primary
Concomitant
Somnolence Required Intervention 3/25/2010 63 Male 4/30/2010 Pharmacist United States
Primary
Secondary
Thrombocytopenia Life Threatening 4/3/2004 45 Male 7/6/2010 Physician Switzerland
Primary
Concomitant
Thrombocytopenia Other Serious 6/21/2010 69 Female 139 lb 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/10/2001 40 Female 179 lb 7/16/2010 United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2010 65 Male 7/23/2010 Physician
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1999 38 Female 179 lb 7/28/2010 United States
Primary
Concomitant
Ventricular Arrhythmia Other Serious 51 Female 251 lb 7/29/2010
Primary
Secondary

Drug Data