Lorazepam combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Other Serious 64 Female 1/3/2006 Consumer Japan
Primary
Secondary
Concomitant
Treatment Noncompliance 1/1/2001 Female 2/8/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 3/1/2005 37 Female 2/8/2006 Consumer United States
Primary
Concomitant
Tooth Loss Other Serious 6/1/2005 47 Male 143 lb 3/11/2006 Pharmacist Netherlands
Primary
Secondary
Concomitant
Cough Other Serious 1/31/2006 74 Male 256 lb 2/10/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/4/2006 66 Female 126 lb 4/6/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2006 74 Male 263 lb 3/23/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 1/4/2005 85 Male 180 lb 3/10/2006 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 4/1/2006 70 Female 8/8/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Tardive Dyskinesia Female 9/14/2006 Consumer United States
Primary
Concomitant
Erythema Other Serious 63 Female 10/19/2006 Consumer France
Primary
Concomitant
Pulmonary Hypertension Other Serious 39 Male 10/19/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 6/10/2006 79 Female 196 lb 11/1/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/31/2006 39 Male 2/2/2007 Other Health Professional France
Primary
Secondary
Concomitant
Erythema Other Serious 11/7/2005 63 Female 2/5/2007 Consumer France
Primary
Concomitant
Sinus Tachycardia Hospitalization 8/2/2004 40 Female 182 lb 8/25/2005 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 4/16/2007 48 Female 234 lb 5/31/2007 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Pharmacist Germany
Primary
Secondary
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Physician Germany
Primary
Secondary
Meningitis Death 11/10/2006 66 Female 11/20/2007 Physician Germany
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/5/2008 73 Female 9/15/2008 Physician France
Primary
Concomitant
Pain Hospitalization 10/5/2008 73 Female 146 lb 10/8/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/5/2008 71 Male 223 lb 10/3/2008 Physician Canada
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 9/17/2008 58 Female 210 lb 10/13/2008 United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 10/15/2007 Female 170 lb 10/22/2008 Consumer Switzerland
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 10/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hypovolaemic Shock Other Serious 12/17/2008 12/22/2008 Physician Argentina
Primary
Secondary
Concomitant
Pneumothorax Traumatic Other Serious 12/17/2008 12/31/2008 Physician Argentina
Primary
Secondary
Concomitant
Pneumothorax Death 12/17/2008 1/28/2009 Physician Argentina
Primary
Secondary
Concomitant
Pneumothorax Death 12/17/2008 2/26/2009 Physician Argentina
Primary
Secondary
Concomitant
Plantar Fasciitis 6/1/2007 Female 220 lb 3/14/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 40 Female 166 lb 5/14/2009 United States
Primary
Concomitant
Pyrexia 2/25/2009 57 Female 225 lb 5/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/1/2006 73 Female 160 lb 6/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 4/19/2005 52 Female 6/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 1/1/2009 Female 178 lb 6/12/2009 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection 4/3/2009 Female 160 lb 6/12/2009 Consumer United States
Primary
Concomitant
Knee Arthroplasty Other Serious 1/1/2006 Male 272 lb 6/10/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 1/1/2008 50 7/14/2009 Pharmacist Canada
Primary
Concomitant
Neuropathy Peripheral Other Serious 8/6/1999 47 Male 232 lb 7/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 42 Male 222 lb 7/23/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/13/2009 Male 275 lb 8/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 44 Female 180 lb 10/5/2009 United States
Primary
Concomitant
Ill-defined Disorder Disability Female 181 lb 10/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ill-defined Disorder Disability Male 331 lb 10/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ill-defined Disorder Disability Male 331 lb 10/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 6/5/2009 64 163 lb 10/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea 9/1/2009 Female 10/16/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/20/2009 83 Male 10/22/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/13/2009 Male 275 lb 10/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/20/2009 83 Male 10/27/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/10/2009 Male 275 lb 11/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue 9/14/2009 62 Female 1/4/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2007 Male 170 lb 2/11/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2007 Male 170 lb 2/22/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Death 6/22/2009 90 Male 1/25/2010 Other Health Professional United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Portal Hypertensive Gastropathy Hospitalization 2/17/2010 Male 123 lb 3/1/2010 Physician Taiwan, Province Of China
Primary
Concomitant
White Blood Cell Count Increased Other Serious 11/19/2008 Male 149 lb 3/16/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 2/1/2008 Female 269 lb 3/17/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/20/2003 Female 203 lb 3/19/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/20/2003 Female 203 lb 3/26/2010 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 11/1/2009 70 Female 149 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 59 Female 4/27/2010 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 4/23/2010 77 Female 106 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Infection Other Serious 3/1/2010 67 Male 5/17/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/6/2009 16 Male 209 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Psoriatic Arthropathy Other Serious 1/1/2009 65 Male 170 lb 5/18/2010 Canada
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/28/2010 68 Female 5/20/2010 Consumer France
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/1/2010 68 Female 5/28/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/16/2010 71 Male 7/5/2010 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2009 64 Female 150 lb 9/14/2010 Consumer United States
Primary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 9/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 10/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 10/9/2010 10/22/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Male 10/22/2010 Physician Canada
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious 10/15/2005 58 Male 11/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Angioedema Other Serious 12/1/2010 68 Male 12/23/2010 Other Health Professional Canada
Primary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Facial Pain Hospitalization 12/28/2000 45 Female 325 lb 2/14/2011 Lawyer United States
Primary
Concomitant
Multiple Drug Overdose Intentional Death 42 Female 2/21/2011 Other Health Professional United States
Primary
Secondary
Pain Other Serious 1/1/2007 66 Female 136 lb 2/24/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Death 42 Female 3/9/2011 Other Health Professional United States
Primary
Secondary
Septic Shock Life Threatening 4/19/2011 42 Female 138 lb 5/3/2011 United States
Primary
Secondary
Concomitant
Psychomotor Hyperactivity Hospitalization 3/22/2011 79 Male 5/17/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Diabetic Neuropathy Hospitalization 1/1/2004 42 Male 219 lb 8/2/2011 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Life Threatening 5/1/2010 57 Female 174 lb 8/10/2011 Consumer United States
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Hospitalization 8/3/2010 57 Male 222 lb 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Bradycardia Life Threatening 1/25/2011 66 Male 9/8/2011 Pharmacist United States
Primary
Concomitant
Epistaxis Hospitalization 5/8/2011 83 Female 152 lb 9/12/2011 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 54 Female 172 lb 10/7/2011 Physician United Kingdom
Primary
Concomitant
Cerebrovascular Accident Death 8/3/2010 57 Male 223 lb 10/10/2011 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 8/3/2010 57 Male 222 lb 10/3/2011 Consumer United States
Primary
Secondary
Concomitant
Gastric Cancer Other Serious Female 10/11/2011 Physician Portugal
Primary
Concomitant
Microangiopathic Haemolytic Anaemia Hospitalization 8/3/2010 57 Male 223 lb 10/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 1/1/2007 66 Female 136 lb 2/21/2012 Consumer Brazil
Primary
Secondary
Concomitant
Asthenia Death 1/1/2010 70 Male 165 lb 2/28/2012 Physician Germany
Primary
Concomitant
Multiple Myeloma Death 11/9/2011 74 Female 3/8/2012 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/23/2011 67 Male 3/9/2012 Other Health Professional Spain
Primary
Concomitant
Fear Hospitalization 1/1/2009 36 Female 176 lb 3/10/2012 Other Health Professional United States
Primary
Concomitant
Cardiogenic Shock Hospitalization 1/23/2011 67 Male 3/13/2012 Other Health Professional Spain
Primary
Concomitant
Hysterectomy Other Serious Female 287 lb 3/19/2012 Physician United States
Primary
Concomitant
Mucosal Inflammation Other Serious 1/31/2011 66 Male 3/14/2012 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious 4/10/2012 22 Female 4/19/2012 Physician Germany
Primary
Secondary
Suffocation Feeling Other Serious 1/17/2012 63 Female 5/3/2012 Pharmacist Serbia
Primary
Concomitant
Hypotension 69 Female 6/26/2012 Physician Italy
Primary
Concomitant
Skin Reaction Hospitalization 11/9/2011 62 Female 165 lb 7/13/2012 Other Health Professional Germany
Primary
Concomitant
Chest Pain Hospitalization 4/1/2010 7/18/2012 Physician United States
Primary
Secondary
Concomitant
Walking Aid User Hospitalization 9/1/2003 70 Male 165 lb 7/6/2012 Lawyer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 67 Male 228 lb 7/25/2012 Consumer United States
Primary
Concomitant
Pancreatic Carcinoma Metastatic Death 7/1/2010 60 Male 7/27/2012 Physician Canada
Primary
Concomitant
Dementia Alzheimer's Type 85 Male 140 lb 7/27/2012 Consumer United States
Primary
Concomitant
Psychomotor Retardation Hospitalization 7/19/2012 65 Female 7/31/2012 Physician Italy
Primary
Secondary
Concomitant
Large Intestinal Obstruction Hospitalization 42 Male 7/31/2012 Other Health Professional United States
Primary
Concomitant
Intentional Drug Misuse 1/1/2011 59 Male 175 lb 8/1/2012 Consumer United States
Primary
Concomitant
Hallucination, Auditory 55 Female 149 lb 8/1/2012 Consumer United States
Primary
Concomitant
Bradyphrenia Hospitalization 7/19/2012 65 Female 8/1/2012 Physician Italy
Primary
Secondary
Concomitant
Bradykinesia Hospitalization 7/19/2012 65 Female 8/2/2012 Physician Italy
Primary
Secondary
Concomitant
Bradyphrenia Other Serious 7/19/2012 65 Female 8/2/2012 Physician Italy
Primary
Secondary
Concomitant
Fracture Delayed Union Other Serious 6/29/2012 72 Female 165 lb 8/1/2012 Consumer Canada
Primary
Concomitant
Intervertebral Disc Degeneration Hospitalization 1/31/2011 75 Male 8/2/2012 Physician Canada
Primary
Concomitant
Dizziness 8/24/2011 81 Female 7/31/2012 Consumer United States
Primary
Concomitant
Brain Neoplasm Malignant Other Serious Male 8/7/2012 Physician United States
Primary
Concomitant
Hyponatraemia Hospitalization 7/19/2012 65 Female 8/9/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 1/31/2011 75 Male 8/9/2012 Physician Canada
Primary
Concomitant
Fall Hospitalization 7/19/2012 65 Female 8/9/2012 Physician Italy
Primary
Secondary
Concomitant
Skin Disorder Hospitalization 7/6/2006 8/13/2012 Lawyer United States
Primary
Secondary
Concomitant
Bradyphrenia Hospitalization 7/19/2012 65 Female 8/14/2012 Physician Italy
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 11/24/2010 65 Female 129 lb 8/15/2012 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/14/2011 8/16/2012 Other Health Professional Germany
Primary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 1/19/2011 67 Male 207 lb 10/25/2012 Physician Us
Primary
Concomitant
Pancreatitis Other Serious 5/2011 40 Female 100 lb 5/17/2012 Physician Us
Primary
Concomitant
Psychomotor Retardation Hospitalization 7/19/2012 65 Female 8/20/2012 Physician It
Primary
Secondary
Concomitant
Sopor Hospitalization 10/18/2012 77 Female 11/28/2012 Physician It
Primary
Concomitant
Sopor Hospitalization 10/18/2012 76 Female 12/3/2012 Physician It
Primary
Concomitant
Toxicity To Various Agents Hospitalization 10/11/2012 39 Female 12/13/2012 Other Health Professional It
Primary
Secondary
Pancreatitis Other Serious 59 Female 12/20/2012 Pharmacist Us
Primary
Concomitant
Pancreatitis Chronic Hospitalization 59 Female 3/1/2013 Other Health Professional Us
Primary
Concomitant
Generalised Oedema Hospitalization 3/12/2013 70 Female 454 lb 4/19/2013 Physician Us
Primary
Secondary
Concomitant
Schizophrenia Hospitalization 2/21/2012 50 Male 178 lb 4/8/2013 Tw
Primary
Concomitant
Vitamin B12 Increased Hospitalization 10/15/2005 58 Male 6/20/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data