Lorazepam combined with Melatonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Ineffective 1/1/2005 79 Female 7/31/2006 Consumer United States
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
Middle Insomnia 5/1/2007 67 Female 167 lb 7/10/2007 Consumer United States
Primary
Concomitant
Blood Bilirubin Unconjugated Increased 1/1/2007 78 Female 11/8/2007 Physician Argentina
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 10/14/2006 11 Female 60 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Hernia Other Serious 3/12/2008 Female 165 lb 7/3/2008 United States
Primary
Concomitant
Productive Cough 2/1/2008 67 Female 8/15/2008 United States
Primary
Concomitant
Suicide Attempt Hospitalization 9/27/2008 Female 154 lb 10/1/2008 Physician Germany
Primary
Secondary
Pain In Extremity Other Serious 9/1/2008 Male 10/24/2008 Consumer Switzerland
Primary
Concomitant
Pain In Extremity Other Serious 9/1/2008 Male 11/17/2008 Consumer Switzerland
Primary
Concomitant
Mood Swings 10/1/2007 62 Female 2/27/2009 Consumer United States
Primary
Concomitant
Wound Complication Other Serious 2/17/2009 Female 3/19/2009 Physician United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 2/17/2009 Female 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 7/14/2009 51 Male 205 lb 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Speech Disorder Disability 53 8/28/2009 Consumer Canada
Primary
Concomitant
Toothache Other Serious 1/1/2008 Female 150 lb 9/9/2009 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 25 Male 10/23/2009 Physician United States
Primary
Secondary
Speech Disorder Disability 53 Female 11/24/2009 Consumer Canada
Primary
Concomitant
Increased Upper Airway Secretion 10/1/2009 Male 12/10/2009 Consumer
Primary
Concomitant
Dysphonia 11/2/2008 54 Male 12/9/2009 Consumer United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 1/15/2010 Male 2/3/2010 United States
Primary
Secondary
Concomitant
Rash Male 1/28/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 1/15/2010 Male 2/12/2010 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 25 Male 2/16/2010 Other Health Professional United States
Primary
Secondary
Pulmonary Oedema Death 25 Male 2/19/2010 Other Health Professional United States
Primary
Secondary
Liver Function Test Abnormal Life Threatening 1/15/2010 Male 2/19/2010 United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 8/20/2009 Female 2/26/2010 United States
Primary
Concomitant
Pulmonary Oedema Death 25 Male 3/9/2010 Physician United States
Primary
Interacting
Substance Abuse Death 25 Male 3/15/2010 Physician United States
Primary
Secondary
Wheezing Other Serious 2/1/2002 3/30/2010 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 2/1/2002 4/5/2010 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 2/1/2002 4/6/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/2002 4/19/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/2002 4/22/2010 Other Health Professional United States
Primary
Concomitant
Oesophageal Disorder 2/1/2009 51 Female 175 lb 5/3/2010 Consumer United States
Primary
Concomitant
Wheezing Other Serious 2/1/2002 5/5/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 223 lb 5/11/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 2/1/2002 5/12/2010 United States
Primary
Concomitant
Wheezing Other Serious 1/1/2003 6/1/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Visual Impairment Other Serious Female 179 lb 6/28/2010 Physician United States
Primary
Concomitant
Middle Insomnia 1/1/2007 54 Female 195 lb 7/12/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Blood Glucose Increased 3/3/2010 70 Male 8/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/26/2002 28 Female 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity 2/26/2010 25 Female 3/16/2010 Other Health Professional United States
Primary
Concomitant
Speech Disorder Disability 53 Female 9/16/2010 Consumer Canada
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Urticaria 7/1/2009 48 Female 9/23/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 8/8/2000 25 Female 10/4/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/2/2010 42 Female 140 lb 10/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 8/8/2000 25 Female 10/12/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/8/2000 25 Female 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 8/8/2000 25 Female 12/14/2010 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Disability 53 Female 11/24/2009 Consumer Canada
Primary
Concomitant
Bone Lesion Hospitalization 8/8/2000 25 Female 1/11/2011 United States
Primary
Secondary
Concomitant
Dry Eye Hospitalization 1/1/2003 1/18/2011 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 8/8/2000 25 Female 1/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Life Threatening 7/14/2009 51 Male 205 lb 3/15/2011 Consumer Germany
Primary
Secondary
Concomitant
Bronchitis Other Serious 8/8/2000 25 Female 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Akathisia Death 4/29/2010 12 Male 46 lb 5/3/2011 Physician United States
Primary
Concomitant
Abdominal Pain Upper Other Serious 2/1/2003 6/24/2011 Physician United States
Primary
Secondary
Concomitant
Performance Status Decreased Hospitalization 7/18/2011 45 Female 1944 lb 7/19/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Metastases To Spine Other Serious 2/1/2003 7/27/2011 Consumer United States
Primary
Secondary
Concomitant
Claustrophobia Male 8/6/2011 Consumer United States
Primary
Concomitant
Hypoxic-ischaemic Encephalopathy Death 7/25/2011 8/22/2011 Physician United States
Primary
Concomitant
Eosinophilia Other Serious 2/1/2003 8/25/2011 Physician United States
Primary
Secondary
Concomitant
Appendicitis Other Serious 9/2/2011 59 Female 205 lb 9/19/2011 Consumer United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 2/1/2003 64 Male 165 lb 9/21/2011 Physician United States
Primary
Secondary
Concomitant
Overweight 1/1/2005 39 Male 293 lb 9/22/2011 Other Health Professional United States
Primary
Concomitant
Adrenal Insufficiency Other Serious 2/1/2003 64 Male 165 lb 10/6/2011 Consumer United States
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 2/1/2003 64 Male 165 lb 10/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Oedema Hospitalization 9/7/2011 60 Female 10/12/2011 Physician Austria
Primary
Secondary
Lumbar Spinal Stenosis Other Serious 2/1/2003 64 Male 165 lb 10/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 7/25/2011 10/19/2011 Consumer United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 9/26/2011 62 Male 166 lb 10/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 9/15/2011 62 Male 166 lb 11/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Joint Stiffness Hospitalization 10/18/2011 12 Male 11/18/2011 Other Health Professional Finland
Primary
Concomitant
Abnormal Behaviour Hospitalization 10/18/2011 12 Male 11/24/2011 Physician Finland
Primary
Concomitant
Vomiting Hospitalization 10/18/2011 12 Male 12/2/2011 Physician Finland
Primary
Concomitant
Haemoglobin Decreased Other Serious 87 Male 164 lb 12/13/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 1/1/2011 56 Male 258 lb 12/25/2011 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 11/21/2011 41 Female 12/27/2011 United States
Primary
Concomitant
Seborrhoeic Keratosis Other Serious 2/1/2003 64 Male 165 lb 12/28/2011 Physician United States
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Life Threatening 9/30/2011 61 Male 124 lb 12/29/2011 Physician United States
Primary
Secondary
Concomitant
Seborrhoeic Keratosis Other Serious 2/1/2003 64 Male 165 lb 1/12/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 1/12/2012 65 Female 140 lb 2/7/2012 Consumer Canada
Primary
Concomitant
Convulsion Other Serious 11/25/2011 36 Male 2/15/2012 Physician Belgium
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/12/2012 65 Female 140 lb 2/28/2012 Canada
Primary
Concomitant
Lipoma Other Serious 2/1/2003 64 Male 165 lb 3/1/2012 Physician United States
Primary
Secondary
Concomitant
Urticaria Female 4/10/2012 Consumer United States
Primary
Concomitant
Arthralgia 11/1/2011 73 Female 189 lb 5/3/2012 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/1/2011 64 Female 140 lb 5/4/2012 Consumer Canada
Primary
Concomitant
Neuropathy Peripheral Other Serious 12 Male 79 lb 5/1/2012 Pharmacist Canada
Primary
Concomitant
Pneumonia Hospitalization 8/1/2011 64 Female 140 lb 5/22/2012 Physician Canada
Primary
Concomitant
Pruritus Other Serious 10/1/2011 12 Male 132 lb 6/7/2012 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious Female 130 lb 6/26/2012 Other Health Professional United States
Primary
Concomitant
Diarrhoea Other Serious 9/20/2011 51 Female 165 lb 6/26/2012 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 62 Male 6/28/2012 Consumer United States
Primary
Concomitant
Malaise 4/23/2012 7/17/2012 Consumer United States
Primary
Concomitant
Constipation Other Serious 2/1/2003 64 Male 165 lb 7/23/2012 Physician United States
Primary
Secondary
Concomitant
Weight Increased 34 Female 115 lb 7/26/2012 Consumer United States
Primary
Concomitant
Dementia Alzheimer's Type 85 Male 140 lb 7/27/2012 Consumer United States
Primary
Concomitant
Flushing Female 118 lb 8/3/2012 Consumer United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 8/2011 Female 140 lb 12/13/2012 Physician Ca
Primary
Concomitant
Thirst Hospitalization 10/2011 Male 132 lb 3/18/2013 Physician Us
Primary
Concomitant
Parosmia 4/23/2012 9/17/2012 Consumer Us
Primary
Concomitant
Rash Hospitalization Female 8/31/2012 Pharmacist Us
Primary
Concomitant
Neuropathy Peripheral Disability 7/25/2012 65 Female 134 lb 2/26/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 11/26/2011 15 Female 119 lb 10/31/2012 Physician Us
Primary
Concomitant
Urinary Incontinence 2011 Female 192 lb 12/6/2012 Consumer Us
Primary
Concomitant
Sepsis Hospitalization 8/6/2012 13 Female 2/15/2013 Physician Us
Primary
Secondary
Concomitant
Cellulitis Hospitalization 11/5/2012 57 Female 12/5/2012 Physician Us
Primary
Secondary
Concomitant
Verbal Abuse Hospitalization 5/2010 Male 1/2/2013 Consumer Us
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 12/7/2012 24 Male 194 lb 12/28/2012 Consumer Ca
Primary
Concomitant
Rash Death 10/2012 Female 12/24/2012 Other Health Professional Us
Primary
Concomitant
Death Death 12/27/2012 44 Female 1/8/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Tinea Pedis Other Serious Female 1/29/2013 Physician Us
Primary
Concomitant
Somnolence Other Serious 10 Male 2/20/2013 Other Health Professional Us
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 10 Male 2/25/2013 Physician Us
Primary
Concomitant
Weight Increased Other Serious 10 Male 2/26/2013 Physician Us
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 10 Male 2/26/2013 Physician Us
Primary
Concomitant
Weight Increased Other Serious NotSpecified 2/28/2013 Other Health Professional Us
Primary
Concomitant
Rash 10/2012 42 Female 2/27/2013 Consumer Us
Primary
Concomitant
Sensory Disturbance Hospitalization 1/3/2013 60 Female 4/2/2013 Physician Us
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 10 Male 3/8/2013 Other Health Professional Country Not Specified
Primary
Secondary
Sleep Apnoea Syndrome Other Serious 10 Male 3/8/2013 Other Health Professional Country Not Specified
Primary
Secondary
Hyperkalaemia Death 12/21/2012 70 Female 225 lb 6/17/2013 Other Health Professional Nl
Primary
Concomitant
Substance-induced Psychotic Disorder Hospitalization 3/2013 49 Female 209 lb 5/14/2013 Consumer Us
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 10 Male 2/28/2013 Physician Us
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/28/2013 61 Female 3/19/2013 Physician Ca
Primary
Concomitant
Drug Ineffective For Unapproved Indication Hospitalization 72 Male 6/11/2013 Other Health Professional Us
Primary
Secondary
Vomiting 4/2013 49 Female 203 lb 5/17/2013 Consumer Us
Primary
Concomitant
Weight Decreased Hospitalization 2010 50 Male 10/29/2012 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2010 50 Male 12/25/2012 Physician Us
Primary
Secondary
Concomitant
Lethargy Hospitalization 4/17/2013 53 Male 7/18/2013 Physician Us
Primary
Secondary
Concomitant
Pneumonia Hospitalization Female 6/7/2013 Physician Us
Primary
Concomitant
Leukopenia Other Serious 9/11/2012 17 Male 6/27/2013 Pharmacist Us
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 2011 82 Female 159 lb 11/16/2012 Physician Us
Primary
Concomitant
Hypertension Hospitalization 83 Female 2/7/2013 Consumer Us
Primary
Concomitant
Vomiting Other Serious 1/27/2012 49 Female 175 lb 7/24/2013 Other Health Professional Us
Primary
Concomitant

Drug Data