Lopinavir combined with Stavudine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatitis Hospitalization Male 3/1/2006 Physician United States
Primary
Secondary
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Death Male 18 lb 5/8/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatitis Hospitalization Male 6/1/2006 Other Health Professional Australia
Primary
Secondary
Von Willebrand's Factor Multimers Abnormal Hospitalization 38 Female 6/7/2006 Belgium
Primary
Secondary
Concomitant
Death Death 4/9/2004 53 Male 7/28/2006 Canada
Primary
Concomitant
Rib Fracture Other Serious 1/6/2004 Female 8/21/2006 Physician Germany
Primary
Concomitant
Neutropenia Other Serious 1/1/2004 Male 1/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 56 Male 126 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 30 Female 97 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Hospitalization 1/1/2005 47 Male 2/28/2007 Spain
Primary
Concomitant
Weight Decreased Hospitalization 32 Male 3/19/2007 Consumer France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 38 Female 4/5/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 8/1/2001 39 Male 5/1/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2005 74 Male 7/26/2007 Spain
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 34 Male 8/10/2007 Other Health Professional Brazil
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Female 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Hospitalization 1/1/1995 Male 10/29/2007 Czech Republic
Primary
Secondary
Premature Rupture Of Membranes Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Male 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Encephalopathy Other Serious 4 Male 12/13/2007 Consumer United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Low Cardiac Output Syndrome Other Serious Male 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Viral Infection Hospitalization 12/13/2007 Other Health Professional United States
Primary
Concomitant
Premature Baby Other Serious 0 Female 12/21/2007 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 12/21/2007 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Female 2/18/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 2/18/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Female 3/14/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 3/14/2008 Netherlands
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 46 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Therapeutic Response Decreased Other Serious 47 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/17/2008 United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 40 Male 1/9/2009
Primary
Secondary
Concomitant
Weight Gain Poor Other Serious 2 Male 4/10/2009 Other Health Professional United States
Primary
Secondary
Hepatotoxicity Other Serious 37 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Lipodystrophy Acquired Other Serious 40 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Other Serious 8/1/2004 45 4/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 52 Male 5/5/2009 Consumer United States
Primary
Secondary
Concomitant
Liver Disorder Other Serious 45 Male 5/8/2009
Primary
Secondary
Liver Disorder Other Serious 42 Male 5/8/2009
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/1/2006 38 Female 6/10/2009 Other Health Professional France
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious 5/1/2007 38 Female 6/10/2009 Other Health Professional France
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious 6/19/2009 Consumer France
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious 6/19/2009 Consumer France
Primary
Secondary
Osteoporosis Other Serious 66 Male 7/10/2009
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious Male 8/24/2009
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious Male 8/24/2009
Primary
Secondary
Chronic Hepatic Failure Other Serious Male 8/24/2009
Primary
Secondary
Varices Oesophageal Hospitalization 46 Female 8/27/2009
Primary
Secondary
Varices Oesophageal Hospitalization 57 Male 8/27/2009
Primary
Secondary
Vascular Injury Hospitalization 48 Female 8/27/2009
Primary
Secondary
Varices Oesophageal Hospitalization 40 Male 8/27/2009
Primary
Secondary
Varices Oesophageal Hospitalization 43 Female 8/27/2009
Primary
Secondary
Pulmonary Hypertension Other Serious 40 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 43 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 46 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/8/2009 Consumer United States
Primary
Secondary
Portal Hypertension Other Serious 46 Female 9/8/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 57 Male 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 40 Male 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 48 Female 9/9/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 43 Female 9/9/2009 Other Health Professional Spain
Primary
Secondary
Tearfulness Hospitalization 9 Female 9/11/2009 Consumer South Africa
Primary
Secondary
Concomitant
Portal Hypertension Other Serious 46 Female 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 57 Male 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 40 Male 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 48 Female 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 43 Female 9/14/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertensive Gastropathy Other Serious 57 Male 9/11/2009 Spain
Primary
Secondary
Varices Oesophageal Other Serious 46 Female 9/11/2009 Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 40 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 46 Female 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 43 Female 9/17/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 54 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Splenomegaly Other Serious 40 Male 9/11/2009
Primary
Secondary
Varices Oesophageal Other Serious 48 Female 9/11/2009
Primary
Secondary
Varices Oesophageal Other Serious 46 Female 9/11/2009
Primary
Secondary
Splenomegaly Other Serious 43 Female 9/11/2009
Primary
Secondary
Portal Hypertensive Gastropathy Other Serious 57 Male 9/11/2009
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/23/2009 Other Health Professional Canada
Primary
Secondary
Portal Hypertension Other Serious 40 9/21/2009 Other Health Professional Spain
Primary
Secondary
Portal Hypertension Other Serious 57 9/21/2009 Other Health Professional Spain
Primary
Secondary
Hypertension Other Serious 46 9/21/2009 Other Health Professional Spain
Primary
Secondary
Thinking Abnormal Hospitalization 9 Female 9/25/2009 Other Health Professional South Africa
Primary
Secondary
Concomitant
Splenomegaly Other Serious 57 Male 9/21/2009 Spain
Primary
Secondary
Portal Hypertension Other Serious 46 Female 9/21/2009 Spain
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/29/2009 Other Health Professional Canada
Primary
Secondary
Serotonin Syndrome Other Serious 9 Female 57 lb 9/30/2009 Other Health Professional South Africa
Primary
Secondary
Interacting
Serotonin Syndrome Other Serious 1/1/2009 9 Female 10/2/2009 Other Health Professional South Africa
Primary
Secondary
Concomitant
Splenomegaly Other Serious 43 Female 9/28/2009
Primary
Secondary
Splenomegaly Other Serious 48 Female 9/28/2009
Primary
Secondary
Splenomegaly Other Serious 40 Male 9/28/2009
Primary
Secondary
Portal Hypertensive Gastropathy Other Serious 46 Female 9/28/2009
Primary
Secondary
Splenomegaly Other Serious 57 Male 9/28/2009
Primary
Secondary
Serotonin Syndrome Hospitalization 9 Female 57 lb 10/5/2009 Physician South Africa
Primary
Concomitant
Interacting
Portal Hypertension Other Serious 48 Female 10/6/2009 Physician Spain
Primary
Secondary
Portal Hypertension Other Serious 43 Female 10/6/2009 Physician Spain
Primary
Secondary
Serotonin Syndrome Hospitalization 9 Female 57 lb 10/12/2009 Other Health Professional South Africa
Primary
Secondary
Concomitant
Ophthalmoplegia Other Serious 52 Male 10/7/2009
Primary
Secondary
Somnolence Other Serious 9 Female 10/9/2009 South Africa
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 10/19/2009 Other Health Professional Canada
Primary
Secondary
Lung Neoplasm Malignant Other Serious 2/1/2009 51 Male 10/22/2009 Physician Poland
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 10/22/2009 Physician United States
Primary
Secondary
Lung Neoplasm Malignant Other Serious 2/1/2009 51 10/28/2009 Physician Poland
Primary
Secondary
Concomitant
Palpitations Hospitalization 7/17/2003 47 Male 11/2/2009 Physician Portugal
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/17/2003 Male 11/6/2009
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 11/24/2009 Other Health Professional United States
Primary
Secondary
Serotonin Syndrome Other Serious 9 Female 57 lb 12/16/2009 Physician South Africa
Primary
Concomitant
Interacting
Treatment Failure Other Serious 2/1/2005 33 Male 2/26/2010 Other Health Professional France
Primary
Secondary
Osteonecrosis Hospitalization 5/1/2005 45 Male 2/26/2010 Other Health Professional France
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/3/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 3/4/2010 Other Health Professional United States
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/8/2010 Physician Canada
Primary
Secondary
Treatment Failure Other Serious 44 Male 3/4/2010 Other Health Professional France
Primary
Secondary
Osteonecrosis Other Serious 5/1/2005 45 Male 3/4/2010 Other Health Professional France
Primary
Secondary
Treatment Failure Other Serious 2/1/2005 33 Male 3/4/2010 Other Health Professional France
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/11/2010 Physician Canada
Primary
Secondary
Virologic Failure Other Serious 44 Male 3/8/2010 Other Health Professional
Primary
Secondary
Treatment Failure Other Serious 2/1/2005 33 Male 3/8/2010 Other Health Professional
Primary
Secondary
Pulmonary Tuberculosis Other Serious 5/1/2005 45 Male 146 lb 3/5/2010 Other Health Professional
Primary
Secondary
Virologic Failure Hospitalization Male 3/26/2010 Physician Brazil
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/1/2010 Physician Canada
Primary
Secondary
Virologic Failure Other Serious 49 Male 4/2/2010 Consumer United States
Primary
Secondary
Virologic Failure Other Serious 6/1/2007 44 Male 4/14/2010 Physician United States
Primary
Secondary
Virologic Failure Hospitalization Male 4/16/2010 Physician United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/28/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 5/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/4/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/7/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 5/7/2010 Consumer United States
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 5/11/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/12/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/13/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/13/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/14/2010 Other Health Professional United States
Primary
Secondary

Drug Data