Lopinavir combined with Ritonavir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachypnoea Hospitalization 45 Male 1/3/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 2/1/1999 41 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Oesophageal Candidiasis Other Serious 50 Male 143 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1999 24 Male 209 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 1/1/1997 49 Male 150 lb 3/23/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 139 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2001 Male 143 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 1/30/2003 40 Male 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2001 56 Female 117 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 8/14/2000 52 Male 154 lb 3/28/2006 Physician Germany
Primary
Secondary
Reflux Oesophagitis Other Serious 6/1/1998 40 Male 181 lb 3/28/2006 Physician Germany
Primary
Secondary
Concomitant
Wrist Fracture Disability 1/1/2003 27 Female 134 lb 3/28/2006 Physician Germany
Primary
Secondary
Concomitant
Urticaria Papular Other Serious 1/1/1994 38 Female 123 lb 3/28/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2001 Male 3/28/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/1997 54 Male 4/17/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2000 34 Female 110 lb 4/17/2006 Physician Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 7/1/2003 Male 163 lb 4/17/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2001 Male 176 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 1/1/2001 Male 198 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/25/2004 Female 82 lb 5/8/2006 Physician Germany
Primary
Concomitant
Vomiting Death Male 18 lb 5/8/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Von Willebrand's Factor Multimers Abnormal Hospitalization 38 Female 6/7/2006 Belgium
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 3/1/2004 66 Male 7/17/2006 Physician France
Primary
Secondary
Concomitant
Pelvic Fracture Other Serious 3/14/2006 Female 187 lb 8/21/2006 Physician Germany
Primary
Concomitant
Neutropenia Other Serious 1/1/2004 Male 1/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 58 Male 123 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 56 Male 126 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 48 Male 132 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 10 Male 49 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious Male 181 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 43 Male 86 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 35 Female 121 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 35 Female 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 41 Male 104 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 60 Male 154 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 30 Female 97 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 58 Male 170 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 47 Male 2/8/2007 Other Health Professional United States
Primary
Secondary
Hiv Infection Cdc Category B3 Other Serious 4/1/2006 40 Male 121 lb 2/13/2007 Physician France
Primary
Secondary
Renal Failure Acute Hospitalization 1/1/2005 47 Male 2/28/2007 Spain
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 38 Female 4/5/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Drug Interaction Other Serious Male 4/23/2007
Primary
Secondary
Renal Tubular Necrosis Other Serious 63 Male 5/14/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Hepatitis B Other Serious 24 Male 5/25/2007 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 50 Male 6/15/2007 Canada
Primary
Concomitant
Renal Failure Acute Other Serious 7/22/2007 Spain
Primary
Secondary
Renal Failure Acute Hospitalization 3/1/2005 74 Male 7/26/2007 Spain
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 34 Male 8/10/2007 Other Health Professional Brazil
Primary
Secondary
Monoparesis Hospitalization 6/14/2007 43 Male 136 lb 8/13/2007 Physician Spain
Primary
Concomitant
Pancreatitis Acute 1/1/2004 Male 8/14/2007 France
Primary
Secondary
Concomitant
Pancreatitis Acute 1/1/2001 Male 8/20/2007 France
Primary
Concomitant
Pelvic Fracture Other Serious 3/14/2006 Female 187 lb 8/24/2007 Physician Germany
Primary
Concomitant
Hepatosplenomegaly Other Serious Male 6 lb 8/28/2007 United States
Primary
Secondary
Monoparesis Hospitalization 6/14/2007 43 Male 136 lb 8/28/2007 Physician Spain
Primary
Concomitant
Retinitis Other Serious 10/15/2000 Male 5 lb 8/29/2007 United States
Primary
Secondary
Trisomy 21 Other Serious Male 5 lb 8/29/2007 United States
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Female 9/10/2007 Czech Republic
Primary
Secondary
Retinitis Other Serious 10/15/2000 Male 5 lb 9/17/2007 United States
Primary
Secondary
Hepatosplenomegaly Other Serious Male 6 lb 9/17/2007 United States
Primary
Secondary
Trisomy 21 Other Serious Male 5 lb 9/19/2007 United States
Primary
Secondary
Weight Decreased Hospitalization 38 Female 9/24/2007 Physician Italy
Primary
Secondary
Pelvic Fracture Other Serious 3/14/2006 Female 187 lb 10/1/2007 Physician Germany
Primary
Concomitant
Splenomegaly Congenital Anomaly 3/27/2002 Male 6 lb 10/17/2007 United States
Primary
Secondary
Drug Resistance Hospitalization 1/1/1995 Male 10/29/2007 Czech Republic
Primary
Secondary
Pancreatitis Acute Hospitalization 1/1/2004 Male 141 lb 11/13/2007 France
Primary
Secondary
Concomitant
Premature Rupture Of Membranes Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Male 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Encephalopathy Other Serious 4 Male 12/13/2007 Consumer United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Low Cardiac Output Syndrome Other Serious Male 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Premature Baby Other Serious Female 12/14/2007 Consumer Netherlands
Primary
Secondary
Viral Infection Hospitalization 12/13/2007 Other Health Professional United States
Primary
Concomitant
Premature Baby Other Serious 0 Female 12/21/2007 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 12/21/2007 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Female 2/18/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 2/18/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Female 3/14/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 3/14/2008 Netherlands
Primary
Secondary
Rhabdomyolysis Hospitalization 63 Male 4/24/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 48 Male 4/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Failure Death 5/15/2008 Other Health Professional Japan
Primary
Secondary
Rhabdomyolysis Hospitalization 63 Male 6/10/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 48 Male 6/10/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 63 Male 6/16/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/18/2008 64 154 lb 6/16/2008 Physician Portugal
Primary
Concomitant
Vomiting Hospitalization 2/18/2008 64 Male 154 lb 7/7/2008 Physician Portugal
Primary
Concomitant
Immune Reconstitution Syndrome Death 7/10/2008 Other Health Professional Japan
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 6/21/2007 26 Female 7/10/2008 Other Health Professional Uganda
Primary
Secondary
Renal Tubular Necrosis Hospitalization 48 Male 7/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 48 Male 7/16/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Death 44 Male 8/1/2008 Consumer Japan
Primary
Secondary
Pregnancy Congenital Anomaly Female 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Pregnancy Other Serious 7/1/2007 33 Female 8/29/2008 Consumer United Kingdom
Primary
Secondary
Pregnancy Congenital Anomaly Female 8/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 46 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Therapeutic Response Decreased Other Serious 47 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/17/2008 United States
Primary
Secondary
Concomitant
Rash Macular Hospitalization 9/12/2008 39 Male 123 lb 10/14/2008 Consumer Portugal
Primary
Concomitant
Pregnancy Other Serious 7/1/2007 33 Female 11/3/2008 Consumer United Kingdom
Primary
Secondary
Pulmonary Embolism Other Serious Unknown 11/5/2008 France
Primary
Concomitant
Cushing's Syndrome Hospitalization 54 Female 12/29/2008 Belgium
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 40 Male 1/9/2009
Primary
Secondary
Concomitant
Pregnancy Other Serious 38 Female 3/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Injection Site Reaction Other Serious 38 Female 3/26/2009 Physician Nigeria
Primary
Secondary
Pregnancy Other Serious 38 Female 3/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Injection Site Reaction Other Serious 38 Female 3/30/2009 Other Health Professional
Primary
Secondary
Weight Gain Poor Other Serious 2 Male 4/10/2009 Other Health Professional United States
Primary
Secondary
Hepatotoxicity Other Serious 37 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Lipodystrophy Acquired Other Serious 40 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Other Serious 8/1/2004 45 4/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 12/12/2008 4/27/2009 Physician Brazil
Primary
Concomitant
Immune Reconstitution Syndrome Death 55 Male 4/29/2009 Other Health Professional Canada
Primary
Secondary
Transaminases Increased Hospitalization 40 Female 4/30/2009 Consumer France
Primary
Secondary
Immune Reconstitution Syndrome Death 55 Male 5/5/2009 Other Health Professional Canada
Primary
Secondary
Liver Disorder Other Serious 45 Male 5/8/2009
Primary
Secondary
Liver Disorder Other Serious 42 Male 5/8/2009
Primary
Secondary
Vasospasm Hospitalization 9/1/2007 43 Female 5/13/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 55 Male 5/12/2009
Primary
Secondary
Nephrogenic Diabetes Insipidus Other Serious 39 Male 5/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 12/1/2006 38 Female 6/10/2009 Other Health Professional France
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious 5/1/2007 38 Female 6/10/2009 Other Health Professional France
Primary
Secondary
Vomiting Life Threatening 10/25/2008 Female 6/16/2009 Consumer France
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 40 Female 6/16/2009 Consumer France
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious 6/19/2009 Consumer France
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious 6/19/2009 Consumer France
Primary
Secondary
Placenta Praevia Other Serious 12/30/2004 Female 6/19/2009 Germany
Primary
Concomitant
Hodgkin's Disease Other Serious 12/12/2008 47 6/22/2009 Physician Brazil
Primary
Concomitant
Pancytopenia Other Serious 6/1/2004 68 Female 6/23/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Interacting
Nephropathy Toxic Other Serious 48 Male 7/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteoporosis Other Serious 65 Female 7/10/2009
Primary
Secondary
Concomitant
Osteoporosis Other Serious 66 Male 7/10/2009
Primary
Secondary
Renal Failure Hospitalization 46 Male 7/27/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Interacting
Hodgkin's Disease Other Serious 11/12/2008 47 7/29/2009 Physician Brazil
Primary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Pregnancy Other Serious 7/1/2007 33 Female 8/3/2009 Consumer United Kingdom
Primary
Secondary
Hodgkin's Disease Other Serious 11/12/2008 47 8/21/2009 Physician Brazil
Primary
Concomitant
Nodular Regenerative Hyperplasia Other Serious Male 8/24/2009
Primary
Secondary
Nodular Regenerative Hyperplasia Other Serious Male 8/24/2009
Primary
Secondary
Chronic Hepatic Failure Other Serious Male 8/24/2009
Primary
Secondary
Varices Oesophageal Hospitalization 46 Female 8/27/2009
Primary
Secondary
Varices Oesophageal Hospitalization 57 Male 8/27/2009
Primary
Secondary
Vascular Injury Hospitalization 48 Female 8/27/2009
Primary
Secondary
Varices Oesophageal Hospitalization 40 Male 8/27/2009
Primary
Secondary

Drug Data