Loperamide combined with Oxaliplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/13/2005 68 Female 148 lb 2/8/2006 Physician Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/13/2005 Female 2/15/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 7/29/2004 Male 2/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fungal Oesophagitis Hospitalization 1/5/2006 Male 3/31/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Diarrhoea Death 7/9/2004 Male 4/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/5/2006 70 Male 4/10/2006 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/4/2005 Female 91 lb 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Disorder Death 7/9/2004 Male 6/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/29/2006 70 Female 7/3/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/19/2005 Female 7/31/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2005 73 Male 8/25/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/18/2006 Female 9/19/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/3/2006 74 Male 10/6/2006 Physician Netherlands
Primary
Secondary
Concomitant
Somnolence Life Threatening 10/1/2006 68 Male 124 lb 11/20/2006 Physician New Zealand
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 11/13/2006 Male 11/20/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 11/13/2006 58 Male 11/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
Performance Status Decreased Hospitalization 10/22/2006 74 Male 206 lb 11/14/2006 United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 10/5/2006 74 Male 206 lb 11/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 10/19/2006 79 Female 121 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Life Threatening 10/1/2006 68 Male 147 lb 11/30/2006 Physician New Zealand
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 11/13/2006 58 Female 110 lb 12/1/2006 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/24/2006 67 Male 137 lb 12/6/2006 Physician New Zealand
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 11/13/2006 58 Male 11/28/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cytokine Release Syndrome Hospitalization 10/20/2006 65 Male 12/8/2006 Physician France
Primary
Secondary
Concomitant
Cytokine Release Syndrome Hospitalization 10/20/2006 65 Male 12/8/2006 Physician France
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2006 69 Male 172 lb 12/12/2006 Physician New Zealand
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 11/7/2006 68 Male 147 lb 1/30/2007 Physician New Zealand
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2006 69 Male 172 lb 2/1/2007 Physician New Zealand
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/7/2006 68 Male 124 lb 11/21/2006 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Injection Site Reaction Hospitalization 12/15/2005 49 Female 214 lb 2/21/2007 Other Health Professional Uruguay
Primary
Secondary
Concomitant
Sudden Death Death 2/18/2007 72 Male 192 lb 3/16/2007 Physician Germany
Primary
Secondary
Concomitant
Abdominal Adhesions Other Serious 1/5/2007 43 Male 3/19/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 12/26/2005 73 Male 3/27/2007 Physician Netherlands
Primary
Secondary
Concomitant
Death Death 2/26/2009 Female 229 lb 6/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Central Line Infection Hospitalization 8/12/2009 Male 9/4/2009 Physician United Kingdom
Primary
Concomitant
Nausea Hospitalization 11/22/2006 Male 9/15/2009 Physician France
Primary
Secondary
Concomitant
Central Line Infection Hospitalization 8/12/2009 Male 9/28/2009 Physician United Kingdom
Primary
Concomitant
Ventricular Fibrillation Death 7/23/2009 Female 174 lb 10/7/2009 Consumer Australia
Primary
Secondary
Concomitant
Myocardial Infarction Death 7/23/2009 Female 10/9/2009 Consumer Australia
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 7/29/2009 62 Female 174 lb 10/13/2009 Consumer Australia
Primary
Concomitant
Malaise Other Serious 9/24/2009 76 Female 108 lb 12/9/2009 Physician United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 9/17/2009 Male 12/14/2009 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 1/15/2008 77 Male 12/28/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 9/17/2009 Male 187 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 9/17/2009 Male 187 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization Male 2/17/2010 Physician United States
Primary
Secondary
Concomitant
Hypertensive Encephalopathy Hospitalization 1/15/2010 Female 148 lb 3/22/2010 Consumer United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 3/10/2010 Female 137 lb 3/23/2010 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Death 1/27/2010 Male 3/31/2010 Physician Netherlands
Primary
Secondary
Concomitant
Hallucination, Visual Hospitalization 65 Female 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Death 1/27/2010 63 Male 4/27/2010 Physician Netherlands
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/10/2010 66 Female 137 lb 4/27/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/11/2010 67 Female 161 lb 5/10/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/25/2010 66 Male 208 lb 6/1/2010 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/10/2002 68 Male 191 lb 6/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 6/11/2010 65 Male 182 lb 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/22/2010 66 Male 208 lb 6/22/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2010 65 Male 6/28/2010 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/10/2010 65 Male 193 lb 7/2/2010 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2010 65 Male 7/7/2010 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2010 65 Male 7/16/2010 Physician Australia
Primary
Secondary
Concomitant
Infection Hospitalization 7/10/2010 54 Male 7/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/11/2010 54 Male 7/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/10/2010 65 Male 193 lb 8/4/2010 Physician Australia
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/11/2010 67 Male 8/10/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/17/2010 67 Female 8/12/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 7/22/2010 70 Male 8/23/2010 Physician Romania
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 4/12/2010 74 Female 132 lb 8/24/2010 Physician Germany
Primary
Secondary
Concomitant
Arrhythmia Death 6/12/2010 65 Male 182 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/2/2010 66 Male 9/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/12/2010 74 Female 132 lb 9/22/2010 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 12/17/2009 69 Male 9/23/2010 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 9/29/2010 77 Female 10/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/18/2010 77 Female 10/8/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Aspiration Life Threatening 9/29/2010 77 Female 11/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 11/9/2010 50 Female 128 lb 11/19/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/5/2010 56 Male 11/29/2010 Physician Netherlands
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 11/9/2010 50 Female 128 lb 12/1/2010 Physician Germany
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 11/11/2010 63 Male 12/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/5/2010 12/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/18/2010 12/15/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/2/2010 55 Female 121 lb 12/16/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/2/2010 55 Female 121 lb 12/27/2010 Physician Germany
Primary
Secondary
Concomitant
Infection Hospitalization 11/11/2010 12/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 11/11/2010 63 Male 12/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 4/12/2010 74 Female 132 lb 1/7/2011 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/2/2010 55 Female 121 lb 1/7/2011 Physician Germany
Primary
Secondary
Concomitant
Blood Magnesium Decreased Hospitalization 11/11/2010 63 Male 1/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 4/2/2010 74 Female 132 lb 1/14/2011 Physician Germany
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 2/10/2010 65 Male 193 lb 1/18/2011 Physician Australia
Primary
Secondary
Concomitant
Dysarthria Hospitalization 3/10/2010 66 Female 137 lb 1/28/2011 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/2/2011 61 Female 176 lb 2/9/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/10/2010 Male 170 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Post Procedural Diarrhoea Hospitalization 2/10/2010 65 Male 193 lb 2/21/2011 Physician Australia
Primary
Secondary
Concomitant
Cardiovascular Disorder Death 2/4/2009 75 Male 154 lb 2/23/2011 Physician Italy
Primary
Secondary
Concomitant
Chills Hospitalization 2/2/2011 61 Female 176 lb 3/1/2011 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/2/2010 55 Female 121 lb 3/21/2011 Physician Germany
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/2/2011 61 Female 176 lb 3/21/2011 Physician Germany
Primary
Secondary
Concomitant
Nausea Hospitalization 2/10/2010 65 Male 193 lb 3/31/2011 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/10/2010 Male 170 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 6/5/2010 59 Male 4/1/2011 Physician Netherlands
Primary
Secondary
Concomitant
Malaise Hospitalization 12/10/2010 Male 170 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/5/2009 75 Male 179 lb 4/26/2011 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/5/2009 75 Male 179 lb 4/26/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 8/2/2010 55 Female 121 lb 4/27/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 9/18/2010 77 Female 6/7/2011 Physician United Kingdom
Primary
Concomitant
Hypokalaemia Hospitalization 9/18/2010 77 Female 6/7/2011 Physician United Kingdom
Primary
Concomitant
Hypokalaemia Other Serious 9/29/2010 77 Female 6/7/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 1/7/2007 47 Female 148 lb 6/10/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Faeces Discoloured Hospitalization 1/7/2007 47 Female 148 lb 6/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 1/7/2007 47 Female 6/23/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 5/31/2011 75 Male 175 lb 6/28/2011 Physician Sweden
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 5/31/2011 75 Male 6/29/2011 Physician Sweden
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 7/14/2009 47 Male 187 lb 6/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Abscess Death 5/25/2011 57 Female 146 lb 7/7/2011 Physician Germany
Primary
Secondary
Concomitant
Urticaria Hospitalization 7/14/2009 47 Male 183 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/4/2011 66 Female 192 lb 7/11/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Disability 7/4/2011 66 Female 192 lb 7/11/2011 Physician Germany
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 5/31/2011 75 Male 175 lb 7/15/2011 Physician Sweden
Primary
Secondary
Concomitant
Folliculitis Hospitalization 8/26/2009 61 Male 228 lb 7/18/2011 Physician France
Primary
Secondary
Concomitant
Folliculitis Hospitalization 8/26/2009 61 Male 228 lb 7/18/2011 Consumer France
Primary
Secondary
Concomitant
Pyoderma Gangrenosum Other Serious 8/26/2009 61 Male 228 lb 7/19/2011 Physician France
Primary
Secondary
Concomitant
Fistula Death 2/16/2011 67 Male 168 lb 7/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Arthritis Reactive Hospitalization 5/14/2011 62 Male 359 lb 7/22/2011 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 7/9/2011 73 Male 198 lb 7/22/2011 Physician Germany
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 5/31/2011 75 Male 7/25/2011 Physician Sweden
Primary
Secondary
Concomitant
Fistula Death 2/16/2011 67 Male 7/25/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Fistula Death 2/16/2011 67 Male 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Infected Neoplasm Death 5/25/2011 57 Female 132 lb 7/27/2011 Physician Germany
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 7/19/2011 36 Male 7/27/2011 Physician United Kingdom
Primary
Concomitant
Nausea Hospitalization 7/19/2011 36 Male 9/15/2011 Physician United Kingdom
Primary
Concomitant
Enterocolitis Hospitalization 9/4/2010 65 Male 136 lb 9/16/2011 Physician Australia
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 9/4/2010 65 Male 134 lb 9/19/2011 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12 Female 9/13/2011 Other Health Professional Germany
Primary
Secondary
Metastases To Liver Hospitalization 3 Female 9/13/2011 Germany
Primary
Secondary
Thrombocytopenia Other Serious 11 Female 9/13/2011 Other Health Professional Germany
Primary
Secondary
Anaemia Hospitalization 15 Male 9/13/2011 Other Health Professional Germany
Primary
Secondary
Leukopenia Other Serious 12 Male 9/13/2011 Other Health Professional Germany
Primary
Secondary
Thrombocytopenia Hospitalization 16 Female 9/13/2011 Other Health Professional Germany
Primary
Secondary
Leukopenia Death 15 Male 9/13/2011 Other Health Professional Germany
Primary
Secondary
Thrombocytopenia Death 15 Male 9/13/2011 Other Health Professional Germany
Primary
Secondary
Haematotoxicity Death 13 Female 9/13/2011 Other Health Professional Germany
Primary
Secondary
Medulloblastoma Recurrent Hospitalization 9 Male 9/13/2011 Other Health Professional Germany
Primary
Secondary
Diarrhoea Hospitalization 13 Male 9/13/2011 Other Health Professional Germany
Primary
Secondary
Haematotoxicity Hospitalization 14 Male 9/13/2011 Other Health Professional Germany
Primary
Secondary
Dehydration Other Serious 8/29/2011 52 Male 115 lb 12/27/2011 Pharmacist Brazil
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/20/2011 71 Female 128 lb 1/5/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/20/2011 Female 128 lb 1/9/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 7/9/2011 Male 198 lb 1/9/2012 Physician Germany
Primary
Secondary
Concomitant

Drug Data