Loperamide combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 11/25/2005 62 Male 1/12/2006 Physician Belgium
Primary
Secondary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Rash Macular Other Serious 9/4/2005 77 Female 194 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Neutropenia Hospitalization 11/28/2005 42 Female 205 lb 1/18/2006 Physician Canada
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 11/25/2005 62 Male 1/23/2006 Physician Belgium
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2005 59 Male 198 lb 1/24/2006 Pharmacist Spain
Primary
Concomitant
Neutropenia Hospitalization 2/13/2005 68 Female 148 lb 2/8/2006 Physician Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/13/2005 Female 2/15/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/15/2005 Male 2/21/2006 Pharmacist United States
Primary
Concomitant
Death Death 3/2/2006 Female 3/15/2006 Physician Canada
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/25/2006 Male 88 lb 3/16/2006 Consumer United States
Primary
Concomitant
Pain Death 75 Female 4/5/2006 Physician Canada
Primary
Concomitant
Pseudomonas Infection Hospitalization 4/9/2006 55 Male 203 lb 5/12/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/9/2006 55 Male 203 lb 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/28/2006 74 Male 8/21/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/9/2006 55 Male 203 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 8/24/2006 82 Female 165 lb 9/29/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/10/2005 75 Male 146 lb 9/25/2006 Physician Spain
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/28/2006 74 Male 10/11/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 10/6/2006 81 Female 154 lb 10/23/2006 Physician United States
Primary
Concomitant
Sepsis Required Intervention 9/19/2006 20 Female 273 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Required Intervention 9/19/2006 20 Female 273 lb 10/19/2006 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 9/25/2006 Female 135 lb 10/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Tachycardia Death 10/14/2006 Female 11/1/2006 Pharmacist United States
Primary
Concomitant
Diarrhoea Hospitalization 10/17/2006 Female 101 lb 11/1/2006 Other Health Professional United States
Primary
Concomitant
Condition Aggravated Hospitalization 2/25/2006 Male 88 lb 11/8/2006 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/28/2006 74 Male 11/13/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2006 69 Male 172 lb 12/12/2006 Physician New Zealand
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2006 69 Male 172 lb 2/1/2007 Physician New Zealand
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 8/4/2007 30 Male 210 lb 10/3/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Hospitalization 11/28/2007 76 Female 2/26/2008 Physician Spain
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 11/4/2004 Female 3/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 1/20/2008 58 Male 6/3/2008 Physician Italy
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/23/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 4/29/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/5/2009 Male 183 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 4/5/2009 Male 183 lb 5/25/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Demyelination Other Serious 3/12/2009 28 Male 129 lb 9/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hip Arthroplasty Other Serious 3/1/2008 Female 9/21/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 6/11/2009 48 Male 176 lb 6/29/2009 Pharmacist United States
Primary
Concomitant
Demyelination Other Serious 3/12/2009 28 Male 129 lb 10/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hip Arthroplasty Other Serious 3/1/2008 Female 10/5/2009 United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 9/22/2009 52 Male 10/5/2009 Pharmacist United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 2/5/2009 Female 119 lb 10/27/2009 Consumer United States
Primary
Secondary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 12/22/2009 Pharmacist Spain
Primary
Concomitant
Scar Other Serious 8/1/2004 Male 12/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 84 lb 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Sepsis Death 1/15/2009 11 Male 83 lb 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 1/23/2010 48 Female 134 lb 2/9/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 83 lb 2/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Peritoneal Disorder Hospitalization 1/23/2010 48 Female 134 lb 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Troponin I Increased Other Serious 7/1/2009 65 Female 3/2/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 3/22/2010 Other Health Professional United States
Primary
Concomitant
Hypokalaemia Other Serious 4/8/2008 55 Male 88 lb 3/26/2010 Physician India
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 3/31/2010 Other Health Professional United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 1/20/1998 88 Female 4/12/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 64 Female 4/14/2010 Other Health Professional United States
Primary
Concomitant
Enterocutaneous Fistula Hospitalization 4/12/2010 60 4/19/2010 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 4/8/2008 55 Male 88 lb 4/26/2010 Physician India
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Weight Increased 4/1/2003 37 Male 5/6/2010 Physician Belgium
Primary
Concomitant
Septic Shock Hospitalization 1/23/2010 34 Male 200 lb 3/10/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 59 Female 130 lb 5/11/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/23/2010 47 Female 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 5/17/2010 44 Male 181 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 4/12/2010 60 203 lb 6/2/2010 Physician Netherlands
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 4/27/2010 53 Female 203 lb 6/10/2010 Physician Netherlands
Primary
Secondary
Concomitant
Demyelination Other Serious 3/6/2009 28 Male 129 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 64 Female 6/15/2010 Other Health Professional United States
Primary
Concomitant
Death Death 6/11/2010 65 Male 182 lb 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 6/11/2010 65 Male 183 lb 6/17/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/1/2008 59 Female 130 lb 6/17/2010 Consumer United States
Primary
Concomitant
Interacting
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/22/2010 United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/16/2009 11 Male 6/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/1/2008 59 Female 130 lb 6/24/2010 Consumer United States
Primary
Concomitant
Interacting
Death Death 68 Female 6/24/2010 Physician United States
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/30/2010 United States
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 7/2/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 7/2/2010 United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/30/2010 61 Female 138 lb 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Temporal Arteritis Other Serious 1/1/2010 68 Female 7/22/2010 Other Health Professional Canada
Primary
Concomitant
Septic Shock Life Threatening 1/13/2009 60 Male 103 lb 7/21/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Drug Interaction Other Serious 22 Female 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Neutropenia Hospitalization 7/17/2010 67 Female 8/12/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/30/2010 61 Female 138 lb 8/17/2010 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 5/1/2010 58 Female 8/11/2010 Other Health Professional United States
Primary
Concomitant
Swelling Hospitalization 7/1/2010 59 Male 8/18/2010 Physician Canada
Primary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 8/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Arrhythmia Death 6/12/2010 65 Male 182 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Arrhythmia Death 6/11/2010 65 Male 183 lb 8/26/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/27/2010 53 Female 203 lb 8/27/2010 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 8/27/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2010 61 Female 9/27/2010 Other Health Professional Netherlands
Primary
Concomitant
Loss Of Consciousness Life Threatening 3/4/2009 60 Male 185 lb 10/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Life Threatening 3/4/2009 60 Male 185 lb 10/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 10/12/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 51 Male 237 lb 10/22/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Atrial Fibrillation Hospitalization Male 170 lb 10/29/2010 Other Health Professional Canada
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Tenderness Hospitalization 10/24/2010 69 Female 184 lb 11/8/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/20/2010 62 Female 137 lb 11/11/2010 Physician Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 11/11/2010 United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Metastatic Hospitalization 12/8/2010 46 Female 109 lb 12/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 12/1/2010 50 Male 225 lb 12/22/2010 Pharmacist United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 40 Male 12/29/2010 Other Health Professional United States
Primary
Concomitant
Hypertension Hospitalization 1/1/2000 51 Male 237 lb 1/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 1/1/2000 51 Male 237 lb 1/21/2011 United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 12/17/2010 50 Male 185 lb 1/13/2011 Physician United States
Primary
Concomitant
Cardio-respiratory Arrest Other Serious 1/1/2008 73 Female 1/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 12/21/2010 81 Male 1/25/2011 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/10/2010 Male 170 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/18/2011 64 Female 237 lb 2/25/2011 Physician United States
Primary
Secondary
Concomitant
Hepatosplenomegaly Death 1/27/2011 68 Male 2/15/2011 Other Health Professional United States
Primary
Concomitant
Aortic Aneurysm Other Serious 1/1/2004 69 Male 142 lb 3/7/2011 Physician United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Death 10/14/2010 49 Male 2/23/2011 Physician United States
Primary
Concomitant
Urticaria Other Serious 12/9/2010 50 Male 225 lb 3/9/2011 Pharmacist United States
Primary
Concomitant
Hydronephrosis Hospitalization 1/19/2011 67 Male 207 lb 2/28/2011 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Death 1/1/2010 61 Female 3/11/2011 Physician Netherlands
Primary
Secondary
Concomitant
Neutropenia Life Threatening 2/9/2011 64 Female 237 lb 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2010 50 Male 225 lb 3/15/2011 Pharmacist United States
Primary
Concomitant
Pancytopenia Other Serious 2/5/2011 59 Female 110 lb 3/10/2011 Consumer Portugal
Primary
Concomitant
Abdominal Distension Other Serious 10/7/2010 49 Male 3/10/2011 Other Health Professional United States
Primary
Concomitant
Nephrogenic Anaemia Other Serious 1/19/2011 67 Male 207 lb 3/4/2011 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 10/11/2009 59 Female 190 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Migraine Other Serious 1/1/2002 65 Male 406 lb 3/23/2011 Lawyer United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 12/21/2010 81 Male 3/30/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/10/2010 Male 170 lb 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Malaise Hospitalization 12/10/2010 Male 170 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Death 3/12/2011 50 Female 231 lb 4/8/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Other Serious 3/12/2011 50 Female 231 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data