Loperamide Hcl combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Liver Disease Life Threatening 7/5/2001 34 Male 2/8/2006 United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 8/17/2005 57 Female 110 lb 2/21/2006 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/12/2006 67 Male 197 lb 6/22/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/12/2006 67 Male 197 lb 6/30/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/12/2006 67 Male 197 lb 7/19/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/12/2006 67 Male 197 lb 8/7/2006 Other Health Professional United States
Primary
Concomitant
Sternal Fracture Other Serious 1/1/2006 64 Female 8/1/2006 Consumer United States
Primary
Concomitant
Weight Increased Life Threatening 12/1/2004 62 Male 160 lb 9/8/2006 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Required Intervention 6/9/2006 56 Male 176 lb 9/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Required Intervention 9/5/2006 60 Female 11/2/2006 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 12/7/2005 55 Male 182 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/10/2005 Male 146 lb 12/29/2006 Spain
Primary
Concomitant
Vomiting Other Serious 8/10/2006 50 Female 134 lb 1/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/12/2006 Male 197 lb 1/11/2007 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 7/1/2006 81 Female 11/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/12/2006 Male 197 lb 1/22/2007 United States
Primary
Concomitant
Pyrexia Hospitalization 10/30/2006 63 Male 229 lb 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Death 1/1/2007 Female 160 lb 3/13/2007 Consumer United States
Primary
Concomitant
Sinus Tachycardia Other Serious 3/8/2007 11 Female 53 lb 3/30/2007 Physician United States
Primary
Concomitant
Pancytopenia Life Threatening 12/1/2006 37 Female 4/12/2007 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 11/25/2005 62 Male 4/20/2007 Physician Belgium
Primary
Secondary
Concomitant
Somnolence Death 1/1/2007 Female 160 lb 5/7/2007 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/4/2006 Male 172 lb 5/17/2007 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Life Threatening 4/29/2007 61 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1999 47 210 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Torsade De Pointes Other Serious 6/2/2007 64 Female 141 lb 7/27/2007 Consumer United Kingdom
Primary
Concomitant
Torsade De Pointes Other Serious 6/2/2007 64 Female 141 lb 7/30/2007 Consumer United Kingdom
Primary
Concomitant
Torsade De Pointes Other Serious 6/2/2007 64 Female 141 lb 7/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Torsade De Pointes Other Serious 6/2/2007 Female 141 lb 8/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/16/2007 44 Female 9/6/2007 Other Health Professional United States
Primary
Concomitant
Overdose Other Serious 1/1/2007 Male 9/21/2007 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 7/11/2007 Male 243 lb 9/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Activated Partial Thromboplastin Time Prolonged Hospitalization 9/18/2007 56 Female 9/27/2007 Consumer United States
Primary
Concomitant
Antiphospholipid Antibodies Positive Hospitalization 9/18/2007 56 Female 10/8/2007 Consumer United States
Primary
Concomitant
Retinal Detachment Hospitalization 9/22/2007 Female 176 lb 10/12/2007 Netherlands
Primary
Concomitant
Pneumonia Hospitalization 7/16/2007 44 Female 10/19/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 8/6/2007 Female 142 lb 11/5/2007 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Pseudomonas Infection Required Intervention 9/27/2007 39 Male 154 lb 11/1/2007 Pharmacist United States
Primary
Concomitant
Immune Reconstitution Syndrome Hospitalization 5/1/2007 53 Male 12/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Other Serious 1/1/2007 Male 154 lb 12/19/2007 Pharmacist United States
Primary
Concomitant
Dysuria 4/8/2007 17 Male 139 lb 4/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Retinal Detachment Hospitalization 9/22/2007 Female 176 lb 12/26/2007 Netherlands
Primary
Concomitant
Speech Disorder Other Serious 12/7/2007 Female 189 lb 2/1/2008 United States
Primary
Concomitant
Swollen Tongue Death 11/4/2004 Female 3/14/2008 Germany
Primary
Secondary
Concomitant
Angina Pectoris Life Threatening 3/20/2008 Female 130 lb 3/25/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 5/9/2007 55 Female 110 lb 3/28/2008 Consumer United States
Primary
Concomitant
Swollen Tongue Death 11/4/2004 71 Female 4/12/2008 United States
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 4/18/2008 Germany
Primary
Secondary
Concomitant
Urticaria Required Intervention 10/12/2007 73 Female 4/15/2008 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 4/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 4/8/2008 Male 88 lb 4/30/2008 India
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 4/8/2008 Male 88 lb 5/14/2008 India
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/5/2008 Male 168 lb 5/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/28/2006 74 Male 207 lb 6/5/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/1/2006 74 Male 207 lb 6/12/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/1/2006 74 Male 207 lb 6/16/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 7/1/2006 74 Male 207 lb 6/18/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 20 Male 132 lb 5/24/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased 6/1/2008 Male 193 lb 9/13/2008 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 9/8/2008 61 Male 141 lb 10/1/2008 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 9/13/2008 Male 10/7/2008 Physician Germany
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 9/8/2008 61 Male 141 lb 10/17/2008 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/3/2008 61 Male 141 lb 11/4/2008 United States
Primary
Secondary
Concomitant
Interacting
Upper Gastrointestinal Haemorrhage Other Serious 9/3/2008 61 Male 141 lb 11/5/2008 United States
Primary
Secondary
Concomitant
Interacting
Clostridium Difficile Colitis Hospitalization 11/5/2008 Female 11/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 4/8/2008 Male 88 lb 11/25/2008 India
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/9/2008 Female 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased 6/1/2008 Male 193 lb 12/12/2008 Consumer United States
Primary
Concomitant
Diarrhoea Death 12/15/2008 Male 132 lb 12/19/2008 Physician Turkey
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 11/5/2008 Female 12/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/7/2008 Female 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/3/2007 Female 1/7/2009 Physician Spain
Primary
Secondary
Concomitant
Lung Disorder Other Serious 12/1/2008 Female 1/14/2009 Consumer United States
Primary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/22/2008 75 Female 172 lb 1/19/2009 Other Health Professional United States
Primary
Concomitant
Death Death 1/29/2009 Female 145 lb 2/4/2009 Other Health Professional United States
Primary
Concomitant
Septic Shock Other Serious 9/13/2008 Male 2/9/2009 Physician Germany
Primary
Concomitant
Pulmonary Hypertension Death Female 145 lb 2/19/2009 Other Health Professional United States
Primary
Concomitant
Ileostomy Hospitalization Male 2/26/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Required Intervention 3/12/2009 28 Male 129 lb 3/12/2009 United States
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 3/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chest Pain Hospitalization 3/11/2009 49 Male 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/15/2007 Female 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious Male 4/22/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 84 lb 4/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/2/2008 Female 115 lb 5/6/2009 Physician Argentina
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/2/2008 Female 115 lb 5/11/2009 Physician Argentina
Primary
Secondary
Concomitant
Vomiting Death 1/15/2009 11 Male 5/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 4/8/2008 55 5/21/2009 Physician India
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/13/2009 47 Female 6/4/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 2/5/2009 Female 119 lb 6/12/2009 Consumer United States
Primary
Secondary
Concomitant
Wound Necrosis Other Serious 1/29/2010 81 Female 5/21/2010 France
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/29/2010 81 Female 5/25/2010 Other Health Professional France
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 45 Female 10/12/2010 Physician
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 3/2/2011 68 Male 3/31/2011 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/2/2011 68 Male 4/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 3/2/2011 68 Male 4/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophosphataemia Hospitalization 3/2/2011 68 Male 5/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophosphataemia Hospitalization 3/2/2011 68 Male 6/5/2011 Consumer United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/2/2011 68 Male 6/7/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 3/22/2011 77 Female 122 lb 7/8/2011 United States
Primary
Concomitant
Dizziness Hospitalization 1/1/2010 61 Female 7/28/2011 Consumer United States
Primary
Concomitant
Metastases To Bone Other Serious 1/1/2005 40 Male 8/1/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Death 6/13/2011 71 Male 211 lb 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/13/2011 71 Male 211 lb 8/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 7/11/2011 76 Female 8/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Life Threatening 7/11/2011 76 Female 8/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Extrasystoles Other Serious 7/1/2009 65 Female 8/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Life Threatening 7/19/2011 76 Female 8/24/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Inferior Vena Caval Occlusion Hospitalization 7/7/2011 55 Female 163 lb 9/9/2011 Consumer United States
Primary
Secondary
Concomitant
Medication Residue Female 9/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 8/15/2011 61 Female 143 lb 9/16/2011 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 61 Female 146 lb 9/20/2011 Physician Canada
Primary
Secondary
Concomitant
Gastrointestinal Disorder Other Serious 81 Female 9/23/2011 Consumer United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 8/15/2011 61 Female 143 lb 9/26/2011 Consumer United States
Primary
Secondary
Concomitant
Enterocolitis Hospitalization Female 9/26/2011 Physician United States
Primary
Secondary
Concomitant
Enterocolitis Hospitalization Female 9/28/2011 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 9/30/2011 Canada
Primary
Secondary
Concomitant
Gastric Neoplasm Other Serious 12/1/2010 66 Male 161 lb 9/30/2011 Other Health Professional Canada
Primary
Concomitant
Death Death 2/20/2011 75 Female 10/10/2011 Physician United States
Primary
Concomitant
Metanephrine Urine Increased Hospitalization 61 Female 146 lb 10/12/2011 Canada
Primary
Concomitant
Hyperglycaemia Other Serious 1/28/2010 62 Female 10/21/2011 Physician United Kingdom
Primary
Concomitant
Confusional State Hospitalization 10/14/2011 61 Male 176 lb 10/25/2011 Physician Netherlands
Primary
Secondary
Concomitant
Abdominal Distension Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Haemodynamic Instability Death 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Respiratory Failure Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Drug Level Increased Hospitalization 61 Female 146 lb 10/25/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Enterocolitis Hospitalization Female 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenia 10/24/2011 64 Male 157 lb 10/31/2011 Physician United States
Primary
Secondary
Concomitant
Lymphopenia 10/31/2011 64 Male 156 lb 10/31/2011 Physician United States
Primary
Secondary
Concomitant
Lymphopenia 10/24/2011 64 Male 157 lb 11/7/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia 10/31/2011 64 Male 156 lb 11/7/2011 Physician United States
Primary
Concomitant
Pneumonia Other Serious 9/2/2011 74 Male 177 lb 11/15/2011 Physician United States
Primary
Concomitant
Cholelithiasis Death 12/1/2007 54 Male 163 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Death 61 Female 146 lb 11/18/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 11/25/2011 11 Female 81 lb 12/16/2011 Physician United States
Primary
Secondary
Concomitant
Lung Disorder Death 10/18/2011 64 Female 12/27/2011 Physician United States
Primary
Concomitant
Tinnitus 8/1/2011 58 Female 1/28/2012 Consumer United States
Primary
Secondary
Concomitant
Eating Disorder Other Serious 1/1/2000 51 Male 237 lb 1/31/2012 United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 1/3/2012 26 Male 132 lb 1/27/2012 Physician Netherlands
Primary
Concomitant
Dyspnoea Other Serious 1/28/2012 47 Male 128 lb 1/31/2012 Consumer United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 11/13/2011 56 Female 134 lb 2/14/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 7/6/2011 47 Female 143 lb 2/16/2012 Physician Netherlands
Primary
Concomitant
Arthralgia Other Serious 9/1/2011 56 Female 2/17/2012 Pharmacist United States
Primary
Concomitant

Drug Data