Livact combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Encephalopathy Other Serious 7/25/2008 72 Male 179 lb 4/8/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 66 Male 6/25/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 66 Male 7/23/2009 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 6/26/2009 77 Male 115 lb 8/18/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 67 Male 112 lb 8/20/2009 Physician Japan
Primary
Concomitant
Nausea Death 7/30/2009 80 Male 97 lb 8/27/2009 Physician Japan
Primary
Concomitant
Respiratory Rate Increased Death 8/10/2009 77 Male 132 lb 9/1/2009 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 7/13/2009 66 Female 106 lb 9/3/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/23/2009 75 Male 117 lb 9/3/2009 Physician Japan
Primary
Concomitant
Liver Disorder Life Threatening 7/6/2009 48 Male 170 lb 9/8/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 9/9/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 8/21/2009 80 Female 9/9/2009 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 6/26/2009 77 Male 115 lb 9/9/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 7/24/2009 70 Male 9/10/2009 Physician Japan
Primary
Concomitant
Hypophosphataemia Hospitalization 7/27/2009 73 Male 132 lb 9/11/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2009 79 Female 9/16/2009 Physician Japan
Primary
Concomitant
Jaundice Hospitalization 7/25/2009 77 Male 132 lb 9/17/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 6/8/2009 67 Male 112 lb 9/18/2009 Physician Japan
Primary
Concomitant
Truncus Coeliacus Thrombosis Hospitalization 7/8/2009 70 Male 106 lb 9/29/2009 Pharmacist Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/11/2009 61 Male 161 lb 10/2/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/19/2009 69 Male 168 lb 10/7/2009 Physician Japan
Primary
Concomitant
Monoplegia Disability 8/21/2009 62 Male 10/16/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Death 6/8/2009 67 Male 112 lb 10/26/2009 Physician Japan
Primary
Concomitant
Nausea Life Threatening 7/30/2009 80 Male 97 lb 10/28/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/14/2009 54 Male 176 lb 10/30/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/2/2009 74 Female 10/30/2009 Physician Japan
Primary
Concomitant
Coma Hepatic Death 9/4/2009 65 Female 84 lb 11/4/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 7/14/2009 60 Male 126 lb 11/4/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 7/3/2009 77 Male 121 lb 11/5/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2009 69 Male 128 lb 11/11/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/11/2009 61 Male 161 lb 11/12/2009 Physician Japan
Primary
Concomitant
Pyrexia 7/24/2009 70 Male 11/13/2009 Physician Japan
Primary
Concomitant
Rash Life Threatening 6/23/2009 72 Male 128 lb 11/20/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 11/23/2009 Physician Japan
Primary
Concomitant
Pruritus Other Serious 7/26/2009 48 Male 123 lb 11/23/2009 Physician Japan
Primary
Concomitant
Renal Impairment Life Threatening 8/26/2009 71 Male 128 lb 11/24/2009 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Death 6/8/2009 67 Male 112 lb 11/30/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/30/2009 61 Male 154 lb 12/1/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/26/2009 85 Male 123 lb 12/3/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Death 9/12/2009 65 Male 12/3/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/28/2009 73 Female 117 lb 12/3/2009 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 6/11/2009 84 Male 110 lb 12/11/2009 Physician Japan
Primary
Concomitant
Monoplegia Disability 8/21/2009 62 Male 12/14/2009 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 11/9/2009 77 Female 12/15/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 12/18/2009 Physician Japan
Primary
Concomitant
Stomatitis Disability 8/12/2009 39 Female 112 lb 12/28/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 10/26/2009 85 Male 123 lb 12/28/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 8/20/2009 80 Female 75 lb 12/28/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/31/2009 62 Female 128 lb 12/29/2009 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 7/14/2009 60 Male 126 lb 12/29/2009 Physician Japan
Primary
Concomitant
Radiation Pneumonitis Other Serious 9/8/2009 74 Female 97 lb 1/14/2010 Physician Japan
Primary
Concomitant
Transaminases Increased Hospitalization 10/23/2009 84 Male 115 lb 1/14/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/23/2009 62 Male 126 lb 1/19/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/2/2009 74 Female 1/20/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 9/3/2009 59 Male 165 lb 1/21/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/16/2009 78 Female 112 lb 1/25/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Death 11/21/2009 71 Male 1/25/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 12/4/2009 56 Male 2/2/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 2/4/2010 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 12/20/2009 77 Male 121 lb 2/4/2010 Physician Japan
Primary
Concomitant
Pyrexia Death 10/8/2009 71 Male 117 lb 2/8/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/17/2009 62 Male 143 lb 2/8/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/29/2009 70 Male 123 lb 2/9/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Death 12/24/2009 69 Male 2/9/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 6/26/2009 77 Male 115 lb 2/11/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/28/2009 73 Female 117 lb 2/12/2010 Physician Japan
Primary
Concomitant
Radiation Pneumonitis Other Serious 9/8/2009 74 Female 97 lb 2/12/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 7/13/2009 56 Male 154 lb 2/12/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 1/1/2009 76 Male 143 lb 2/12/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 12/4/2009 56 Male 2/16/2010 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 7/26/2006 75 Male 132 lb 2/22/2010 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Other Serious 6/8/2009 67 Male 112 lb 2/23/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/29/2009 72 Male 130 lb 2/23/2010 Physician Japan
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 7/27/2009 73 Male 132 lb 2/23/2010 Physician Japan
Primary
Concomitant
Pleural Haemorrhage Death 1/8/2010 74 Male 126 lb 3/4/2010 Physician Japan
Primary
Concomitant
Erythema Multiforme Other Serious 7/9/2009 84 Male 110 lb 3/4/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/14/2009 54 Male 176 lb 3/5/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 10/23/2009 84 Male 115 lb 3/9/2010 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 12/12/2009 75 Male 134 lb 3/15/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 3/15/2010 Other Health Professional Japan
Primary
Concomitant
Hepatic Encephalopathy Hospitalization 1/17/2010 72 Male 141 lb 3/22/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 6/17/2009 62 Male 143 lb 3/23/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 3/25/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 3/26/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Hospitalization 1/4/2010 76 Male 106 lb 3/26/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 3/30/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Death 1/19/2010 73 Male 3/31/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/31/2009 62 Female 128 lb 4/6/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Hospitalization 2/15/2010 76 Male 4/7/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 6/26/2009 77 Male 115 lb 4/12/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/16/2009 78 Female 112 lb 4/12/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 12/3/2009 71 Male 141 lb 4/13/2010 Physician Japan
Primary
Concomitant
Hepatic Encephalopathy Other Serious 7/25/2008 72 Male 179 lb 4/14/2010 Physician Japan
Primary
Concomitant
Hepatic Failure Life Threatening 6/26/2009 77 Male 115 lb 4/15/2010 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 7/13/2009 66 Female 106 lb 4/20/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/29/2009 70 Male 123 lb 4/20/2010 Physician Japan
Primary
Concomitant
Prothrombin Level Decreased Death 7/29/2009 80 Male 106 lb 4/20/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 4/21/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 4/23/2010 Other Health Professional Japan
Primary
Concomitant
Hypertension Hospitalization 9/14/2009 76 Male 4/23/2010 Physician Japan
Primary
Concomitant
Rash Life Threatening 6/23/2009 72 Male 128 lb 4/23/2010 Physician Japan
Primary
Concomitant
Monoplegia Disability 8/21/2009 62 Male 4/26/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 4/28/2010 Physician Japan
Primary
Concomitant
Weight Decreased Death 12/3/2009 71 Male 141 lb 4/30/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 6/1/2009 62 Male 5/3/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 6/1/2009 62 Male 5/3/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/9/2009 76 Male 123 lb 5/7/2010 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 12/12/2009 75 Male 134 lb 5/7/2010 Physician Japan
Primary
Concomitant
Pruritus Other Serious 7/26/2009 48 Male 123 lb 5/11/2010 Physician Japan
Primary
Concomitant
Weight Decreased Death 12/3/2009 71 Male 141 lb 5/12/2010 Physician Japan
Primary
Concomitant
Pyrexia Death 10/8/2009 71 Male 117 lb 5/13/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 9/1/2009 77 Male 159 lb 5/18/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 79 Female 5/19/2010 Physician Japan
Primary
Concomitant
Hypertension Other Serious 2/4/2010 78 Male 132 lb 5/26/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 5/27/2010 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/17/2009 75 Female 5/27/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/22/2009 77 Male 132 lb 6/1/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 7/27/2009 39 Female 112 lb 6/3/2010 Physician Japan
Primary
Concomitant
Liver Disorder Life Threatening 4/15/2010 62 Male 179 lb 6/4/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 9/22/2009 69 Male 128 lb 6/7/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Death 8/24/2009 80 Male 104 lb 6/10/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 7/9/2009 69 Female 99 lb 6/10/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 12/19/2008 59 Male 183 lb 6/17/2010 Physician Japan
Primary
Concomitant
Oedema Life Threatening 1/6/2010 91 Female 143 lb 6/23/2010 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 5/17/2010 77 Male 6/23/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 6/23/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 7/7/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 7/2/2009 68 Male 126 lb 7/12/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Hospitalization 12/25/2009 73 Male 137 lb 7/12/2010 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 5/25/2010 79 Female 110 lb 7/12/2010 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Other Serious 6/8/2009 67 Male 112 lb 7/16/2010 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 12/18/2009 64 Male 7/22/2010 Physician Japan
Primary
Concomitant
Liver Disorder Death 11/14/2008 65 Female 88 lb 7/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 7/27/2010 Physician Japan
Primary
Concomitant
Rash Hospitalization 6/27/2009 73 Female 115 lb 7/26/2010 Physician Japan
Primary
Concomitant
Metabolic Encephalopathy Other Serious 6/8/2009 67 Male 112 lb 7/27/2010 Other Health Professional Japan
Primary
Concomitant
Hyperammonaemia Hospitalization 12/25/2009 73 Male 137 lb 7/28/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/22/2010 76 Male 141 lb 7/30/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/5/2009 67 Female 119 lb 8/3/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 9/14/2009 74 Male 115 lb 8/3/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/15/2010 76 Male 8/4/2010 Physician Japan
Primary
Concomitant
Rash Other Serious 7/29/2009 70 Male 123 lb 8/9/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 11/1/2009 57 Male 130 lb 8/10/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/22/2010 76 Male 141 lb 8/10/2010 Physician Japan
Primary
Concomitant
Drug Eruption Hospitalization 5/25/2010 79 Female 110 lb 8/11/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 6/26/2010 72 Male 108 lb 8/11/2010 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 1/22/2010 76 Male 141 lb 8/12/2010 Physician Japan
Primary
Concomitant
Renal Failure Life Threatening 7/13/2009 66 Female 106 lb 8/13/2010 Physician Japan
Primary
Concomitant
Hypertension Hospitalization 9/14/2009 76 Male 8/25/2010 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 6/3/2010 49 Male 181 lb 8/27/2010 Physician Japan
Primary
Concomitant

Drug Data