Lithium Carbonate combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Hospitalization 69 Male 1/3/2006 France
Primary
Concomitant
Toxic Epidermal Necrolysis Disability 17 Female 1/19/2006 Australia
Primary
Secondary
Pyrexia Hospitalization 7/7/2004 56 Male 89 lb 1/31/2006 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 8/9/2005 54 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/31/2006 73 Female 3/21/2006 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Thrombocythaemia Required Intervention 5/1/2005 46 Male 12/14/2005 Physician United States
Primary
Concomitant
Psychotic Disorder Other Serious 10/8/2005 25 Female 3/31/2006 Physician Germany
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 32 Male 4/6/2006 Japan
Primary
Concomitant
Toxic Induced Encephalopathy Other Serious 32 Male 4/12/2006 Japan
Primary
Concomitant
Weight Increased Hospitalization 12/15/2005 50 Male 4/5/2006 Physician France
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/1/2005 Male 6/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ovarian Enlargement Other Serious 5/11/2006 34 Female 187 lb 6/20/2006 Physician Germany
Primary
Concomitant
Therapy Non-responder Other Serious 17 Female 6/27/2006 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 53 Male 7/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Conversion Disorder Other Serious 3/25/2006 58 Female 198 lb 7/3/2006 Physician United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/26/2005 36 Male 259 lb 1/17/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 9/6/2005 46 Male 5/24/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/27/2005 70 Female 228 lb 3/9/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/16/2005 38 Male 135 lb 2/10/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/17/2006 38 Male 115 lb 6/6/2006 Consumer United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 3/25/2006 58 Female 198 lb 7/27/2006 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 20 Female 8/23/2006 Pharmacist Ireland
Primary
Concomitant
Renal Failure Chronic Death 21 Male 9/25/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 21 Male 9/25/2006 United States
Primary
Concomitant
Treatment Noncompliance Death 8/1/2006 58 Male 9/28/2006 Other Health Professional Australia
Primary
Concomitant
Mania Hospitalization 2/17/2006 56 Female 10/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Psychomotor Retardation Hospitalization 5/24/2005 67 Male 10/25/2006 Consumer Australia
Primary
Secondary
Concomitant
Mania Hospitalization 2/17/2006 56 Female 10/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/5/2006 30 Female 10/27/2006 Switzerland
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/16/2006 51 Male 11/21/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Completed Suicide Death 12/23/2006 36 Female 137 lb 1/20/2007 Physician Mexico
Primary
Secondary
Concomitant
Completed Suicide Death 12/23/2006 36 Female 137 lb 1/26/2007 Physician Mexico
Primary
Secondary
Concomitant
Tearfulness Other Serious Female 2/6/2007 Physician United Kingdom
Primary
Concomitant
Tremor Hospitalization 49 Female 2/2/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Balance Disorder Hospitalization 1/1/2006 60 Female 2/23/2007 Physician Australia
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10 Male 3/7/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Hospitalization 49 Female 3/5/2007 Physician United States
Primary
Concomitant
No Therapeutic Response Hospitalization 7/1/2003 45 Male 3/15/2007
Primary
Secondary
Sudden Death Death 39 Male 3/23/2007 Physician Australia
Primary
Secondary
Concomitant
Tremor Hospitalization 60 Female 4/5/2007 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 2/1/2007 16 Female 3/29/2007 Other Health Professional United States
Primary
Secondary
Ovarian Enlargement Other Serious 5/11/2006 34 Female 187 lb 4/2/2007 Physician Germany
Primary
Concomitant
Sudden Death Death 39 Male 4/7/2007 Physician Australia
Primary
Secondary
Mania Hospitalization 39 Male 4/18/2007 Australia
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 60 Female 4/19/2007
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 60 Female 4/23/2007 Taiwan, Province Of China
Primary
Concomitant
Interacting
Rash Other Serious 2/20/2007 30 Female 176 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Brugada Syndrome Other Serious 39 Male 4/26/2007 France
Primary
Secondary
Rash Other Serious 2/20/2007 30 Female 176 lb 4/25/2007 United Kingdom
Primary
Concomitant
Psychomotor Retardation Other Serious 61 Female 4/25/2007 Physician Japan
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 41 Male 5/4/2007 Switzerland
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2007 36 Female 5/16/2007 Consumer Australia
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2007 36 Female 5/17/2007 Consumer Australia
Primary
Concomitant
Tremor Hospitalization 60 Female 5/15/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Surgery Hospitalization Male 5/30/2007 Physician New Zealand
Primary
Concomitant
Sinusitis Other Serious 11/11/2004 Male 199 lb 6/29/2007 Consumer United States
Primary
Secondary
Concomitant
Sudden Death Hospitalization 1/1/2006 39 Male 6/27/2007 Other Health Professional Australia
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 37 Female 9/5/2007
Primary
Secondary
Syncope Hospitalization 36 Male 9/19/2007
Primary
Secondary
Musculoskeletal Stiffness Hospitalization Female 12/5/2007 Consumer Australia
Primary
Concomitant
Sleep Apnoea Syndrome Disability 1/1/2007 45 Male 216 lb 12/14/2007 Physician Netherlands
Primary
Concomitant
Urticaria Hospitalization 3/4/2007 31 Female 1/18/2008 Consumer Sweden
Primary
Concomitant
Toxic Encephalopathy Other Serious 4/1/2007 Female 1/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 2/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Tachycardia Other Serious 2/1/2008 61 Female 2/27/2008 Physician Japan
Primary
Concomitant
Toxic Encephalopathy Hospitalization 1/1/2007 65 Male 3/4/2008 Physician Australia
Primary
Secondary
Interacting
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 3/6/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Tachycardia Other Serious 2/1/2008 61 Female 3/11/2008 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 12/9/2007 28 Male 3/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Suicide Attempt Other Serious 31 Male 3/25/2008 Japan
Primary
Concomitant
Urinary Incontinence Disability 1/1/2008 49 Male 4/11/2008 Physician United Kingdom
Primary
Concomitant
Antipsychotic Drug Level Increased Hospitalization 36 Female 5/28/2008 Consumer Australia
Primary
Concomitant
Interacting
Pyrexia Other Serious 9/22/2006 68 Male 5/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 2/8/2005 57 Male 6/9/2008 United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 3/12/2008 21 Male 6/13/2008 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 3/12/2008 21 Male 6/19/2008 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 3/12/2008 21 Male 6/30/2008 Physician United States
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 57 Male 7/3/2008
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Male 7/9/2008 Physician United States
Primary
Secondary
Concomitant
Long Qt Syndrome Hospitalization 17 8/4/2008 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 17 8/8/2008 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 17 Male 8/11/2008 Other Health Professional Japan
Primary
Concomitant
Staring Other Serious 1/1/2008 Male 209 lb 9/11/2008 Physician Germany
Primary
Secondary
Concomitant
Herpes Zoster 3/26/2008 Male 250 lb 9/12/2008 Physician United States
Primary
Concomitant
Cough Death 9/4/2008 48 Female 9/19/2008 Physician Uruguay
Primary
Concomitant
Left Ventricular Hypertrophy Other Serious Male 10/28/2008 Other Health Professional Australia
Primary
Concomitant
Tremor Other Serious 61 Female 12/16/2008 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 44 Female 1/23/2009
Primary
Secondary
Concomitant
Parathyroid Tumour Benign Hospitalization 65 Female 1/23/2009
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 24 Male 1/29/2009 Other Health Professional Japan
Primary
Concomitant
Neurotoxicity Other Serious 2/18/2009
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 48 Male 2/24/2009
Primary
Secondary
Periorbital Oedema Other Serious 43 Female 2/20/2009 Canada
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 12/1/2005 Male 3/5/2009 Physician Japan
Primary
Concomitant
Thyroiditis Other Serious 61 Female 3/10/2009
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 28 Male 3/27/2009 United Kingdom
Primary
Secondary
Vomiting Other Serious 4/1/2009 Female 5/4/2009 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 4/1/2009 Female 5/14/2009 Other Health Professional
Primary
Secondary
Vomiting Other Serious 1/1/2009 21 Female 5/14/2009 Other Health Professional United States
Primary
Secondary
Inappropriate Schedule Of Drug Administration Hospitalization 11/15/2005 Male 265 lb 5/26/2009 Physician Germany
Primary
Concomitant
Overweight Other Serious 37 Male 5/25/2009 Germany
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 11/15/2005 Male 265 lb 6/10/2009 Physician Germany
Primary
Concomitant
Atrioventricular Block Complete Life Threatening 1/1/2005 57 Male 6/16/2009 Physician Japan
Primary
Secondary
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2008 40 Male 9/3/2009
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2007 76 Male 128 lb 10/6/2009
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 28 Female 10/9/2009 Physician Turkey
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 28 Female 10/23/2009 Physician Turkey
Primary
Secondary
Concomitant
Tremor Other Serious 10/10/2008 41 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 10/27/2009 Other Health Professional Turkey
Primary
Secondary
Tremor Other Serious 41 Female 10/29/2009 Other Health Professional France
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious 10/16/2009 20 Female 101 lb 10/30/2009 Physician China
Primary
Concomitant
Tremor Other Serious 41 Female 11/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Somnolence Other Serious 3/1/2007 42 Male 11/5/2009 Physician India
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 27 Male 11/17/2009
Primary
Secondary
Concomitant
Therapy Cessation Other Serious Female 11/19/2009 Pharmacist Ireland
Primary
Concomitant
Heart Rate Decreased Other Serious 10/16/2009 20 Female 101 lb 11/30/2009 Physician China
Primary
Concomitant
Atrioventricular Block Hospitalization 5/19/2009 70 Male 12/2/2009 Physician Germany
Primary
Secondary
Interacting
Heart Rate Decreased Other Serious 10/16/2009 20 Female 101 lb 1/4/2010 Physician China
Primary
Concomitant
Fluid Retention Other Serious Female 161 lb 1/5/2010 Physician Spain
Primary
Concomitant
Metabolic Syndrome Hospitalization 28 Female 1/8/2010 France
Primary
Secondary
Metabolic Syndrome Hospitalization 28 Female 1/26/2010 France
Primary
Secondary
Treatment Noncompliance Hospitalization 40 Female 2/1/2010 United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 37 Female 3/17/2010
Primary
Secondary
Serotonin Syndrome Life Threatening 1/24/2010 77 Female 3/18/2010 Physician France
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 1/24/2010 77 Female 4/2/2010 France
Primary
Secondary
Concomitant
Mental Impairment Hospitalization Male 4/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypothyroidism Other Serious Male 4/19/2010 Physician United Kingdom
Primary
Concomitant
Periodontitis Other Serious 42 Male 4/29/2010 Other Health Professional Japan
Primary
Concomitant
Status Epilepticus Life Threatening 41 Male 5/13/2010 Consumer South Africa
Primary
Concomitant
Tooth Resorption Other Serious 6/4/2007 42 Male 5/20/2010 Japan
Primary
Concomitant
Treatment Noncompliance Other Serious 2/1/2010 44 Male 187 lb 5/21/2010 Physician United Kingdom
Primary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 6/10/2010 United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 2/1/2010 44 Male 187 lb 6/24/2010 Physician United Kingdom
Primary
Concomitant
Hypothyroidism Other Serious 6/1/2009 44 Male 7/1/2010 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious Male 7/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/12/2010 43 Male 8/10/2010 Pharmacist United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 55 Male 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Other Serious 53 Female 9/13/2010 Physician New Zealand
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 12 Female 9/17/2010 United States
Primary
Concomitant
Sinus Bradycardia Other Serious 27 Male 9/20/2010
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/1/2010 45 Male 9/29/2010 Physician United Kingdom
Primary
Concomitant
Hypothermia Other Serious Male 157 lb 9/30/2010 Pharmacist United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 2/1/2010 44 Male 187 lb 10/20/2010 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 6/1/2010 50 Male 11/5/2010 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data