Lisinopril combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Life Threatening 6/5/2006 Female 7/27/2006 Consumer United States
Primary
Concomitant
Somnolence Life Threatening 6/5/2006 Female 336 lb 8/18/2006 Consumer United States
Primary
Concomitant
Somnolence Life Threatening 6/5/2006 Female 336 lb 9/6/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/25/2006
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 67 Male 10/6/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/26/2006 69 Male 221 lb 10/5/2006 Pharmacist United States
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Sluggishness 9/7/2006 Male 289 lb 1/12/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/29/2007 52 Female 321 lb 9/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 4/1/2008 57 Male 223 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Subdural Haematoma Hospitalization 9/7/2007 Female 152 lb 7/11/2008 Physician United States
Primary
Secondary
Concomitant
Nasal Congestion 8/27/2008 61 Male 10/14/2008 Consumer United States
Primary
Concomitant
Blood Glucose Increased 8/1/2008 Female 11/26/2008 United States
Primary
Concomitant
Pruritus 9/23/2008 Female 11/26/2008 United States
Primary
Concomitant
Subdural Haematoma Hospitalization 9/7/2007 63 Female 152 lb 1/8/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 7/26/2008 Male 172 lb 2/2/2009 Consumer United States
Primary
Concomitant
Nephropathy Toxic Other Serious 1/15/2009 76 Female 110 lb 3/31/2009 Pharmacist United States
Primary
Concomitant
Vaginal Haemorrhage 6/23/1999 28 Female 194 lb 4/15/2009 Other Health Professional United States
Primary
Concomitant
Death Death 7/26/2008 Male 172 lb 4/17/2009 Consumer United States
Primary
Concomitant
Meningitis Hospitalization 5/20/2006 53 Female 5/19/2009 United States
Primary
Concomitant
Swelling Face Other Serious Female 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious Female 8/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious Female 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Other Serious 3/30/2001 48 Male 265 lb 9/23/2009 United States
Primary
Concomitant
Simple Partial Seizures Other Serious 7/23/2009 Male 174 lb 9/30/2009 Consumer Portugal
Primary
Concomitant
Weight Decreased Other Serious 2/1/2008 45 Female 256 lb 10/14/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 137 lb 11/25/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 Female 1/6/2010 Consumer United States
Primary
Concomitant
Respiratory Arrest Death 49 Male 1/11/2010 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 49 Male 1/15/2010
Primary
Secondary
Drug Toxicity Other Serious 49 Male 1/25/2010 Physician United States
Primary
Secondary
Angioedema Other Serious 1/14/2010 Female 296 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Poisoning Life Threatening 1/1/2008 49 Male 2/1/2010 Physician United States
Primary
Secondary
Completed Suicide Death 49 Male 2/2/2010 United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 49 Male 2/2/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 1/1/2008 49 Male 2/1/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 49 Male 2/19/2010
Primary
Secondary
Completed Suicide Death 49 Male 2/26/2010 Other Health Professional United States
Primary
Secondary
Angioedema Other Serious 1/14/2010 Female 295 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Completed Suicide Death 49 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Angioedema Other Serious 1/14/2010 Female 295 lb 3/16/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2008 49 Male 3/25/2010 Other Health Professional United States
Primary
Secondary
Pain In Extremity Other Serious Female 168 lb 4/6/2010 Consumer United States
Primary
Concomitant
Hypertension Hospitalization 1/4/2010 81 Female 4/28/2010 Physician United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 7/1/2009 67 Female 5/19/2010 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 11/1/2009 50 Female 160 lb 6/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Laryngeal Oedema Life Threatening 3/23/2009 57 Female 7/27/2010 Pharmacist United States
Primary
Concomitant
Mood Altered Other Serious 3/16/2010 24 Female 225 lb 5/18/2010 United States
Primary
Concomitant
Vitamin D Decreased 8/1/2008 55 Female 240 lb 8/3/2010 Consumer United States
Primary
Concomitant
Skin Burning Sensation 10/15/2009 51 Female 203 lb 8/28/2010 Consumer United States
Primary
Secondary
Concomitant
Rash 6/1/2010 64 Male 210 lb 8/29/2010 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/1/2006 53 Female 163 lb 9/8/2010 United States
Primary
Concomitant
Oedema Peripheral 8/1/2010 54 Female 229 lb 9/23/2010 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/1/2008 36 Female 230 lb 9/14/2010 Consumer United States
Primary
Concomitant
Burning Mouth Syndrome Other Serious 54 Female 10/7/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/1/2010 54 Female 179 lb 10/11/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 47 Female 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Burning Mouth Syndrome Other Serious 10/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Burning Mouth Syndrome Other Serious 54 Female 10/21/2010
Primary
Secondary
Nausea Other Serious 10/1/2010 47 Female 10/29/2010 Consumer United States
Primary
Secondary
Concomitant
Angioedema Other Serious 1/14/2010 51 Female 295 lb 10/29/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2009 46 Female 11/12/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2009 11/15/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 6/1/2010 49 Female 10/25/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2009 11/29/2010 Physician United States
Primary
Concomitant
Drug Ineffective 10/1/2009 62 Male 11/29/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/14/2010 51 Female 295 lb 12/13/2010 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/1/2010 46 Female 200 lb 12/1/2010 Consumer United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 1/14/2010 51 Female 295 lb 12/16/2010 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 43 Male 172 lb 12/17/2010 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 47 Female 12/17/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Stroke Other Serious 1/1/2008 36 Female 230 lb 12/13/2010 Consumer United States
Primary
Concomitant
Completed Suicide Death 41 Male 1/4/2011 Other Health Professional United States
Primary
Secondary
Dry Mouth Other Serious 54 Female 12/30/2010 Other Health Professional United States
Primary
Concomitant
Toxicity To Various Agents Death 41 Male 1/12/2011 Physician United States
Primary
Secondary
Restless Legs Syndrome Other Serious Male 1/7/2011 Lawyer United States
Primary
Concomitant
Memory Impairment 11/5/2010 49 Female 195 lb 1/30/2011 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 1/1/2009 41 Male 1/19/2011 Other Health Professional United States
Primary
Concomitant
Blood Glucose Fluctuation Other Serious 3/7/2010 58 Female 2/9/2011 Physician Canada
Primary
Concomitant
Respiratory Arrest Death 1/1/2009 41 Male 1/26/2011 Physician United States
Primary
Secondary
Completed Suicide Death 41 Male 1/28/2011 Other Health Professional Denmark
Primary
Secondary
Cardio-respiratory Arrest Death 41 Male 3/6/2011 Physician United States
Primary
Secondary
Hypertension Hospitalization 1/5/2010 81 Female 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 1/14/2010 52 Female 295 lb 3/23/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 41 Male 3/30/2011 Physician United States
Primary
Secondary
Blood Glucose Increased Other Serious 3/7/2010 58 Female 4/29/2011 Physician Canada
Primary
Concomitant
Hypotension Other Serious 8/1/2010 45 Female 236 lb 5/3/2011 Consumer United States
Primary
Secondary
Concomitant
Intentional Overdose Other Serious 6/1/2008 59 Female 5/6/2011 Lawyer United States
Primary
Concomitant
Oesophageal Oedema Other Serious 2/1/2011 49 Female 184 lb 5/10/2011 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2003 50 Male 165 lb 5/27/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 1/27/2006 40 Female 5/18/2011 Physician United States
Primary
Concomitant
Polycystic Ovaries Other Serious 1/1/2008 36 Female 240 lb 6/8/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2008 36 Female 240 lb 7/6/2011 Pharmacist United States
Primary
Concomitant
Blindness Other Serious 3/7/2010 58 Female 7/20/2011 Canada
Primary
Concomitant
Toxicity To Various Agents Death 1/1/2008 49 Male 7/22/2011 Physician United States
Primary
Secondary
Chest Discomfort Other Serious 3/7/2010 58 Female 8/15/2011 Physician Canada
Primary
Concomitant
Respiratory Distress Hospitalization 46 Male 8/23/2011 Physician United States
Primary
Secondary
Constipation Other Serious 1/1/2008 36 Female 235 lb 8/18/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hip Arthroplasty Other Serious 1/1/2006 76 Male 144 lb 9/2/2011 Consumer United States
Primary
Concomitant
Toxic Anterior Segment Syndrome Other Serious 7/14/2011 62 Male 310 lb 8/30/2011 Pharmacist United States
Primary
Concomitant
Hypothyroidism Hospitalization 12/1/2010 46 Female 160 lb 8/31/2011 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 1/26/2010 57 Female 9/7/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 3/7/2010 58 Female 9/13/2011 Physician Canada
Primary
Concomitant
Pollakiuria Other Serious 3/7/2010 58 Female 9/16/2011 Physician Canada
Primary
Concomitant
Oedema Peripheral Other Serious 3/7/2010 58 Female 10/18/2011 Canada
Primary
Concomitant
Nausea 11/5/2010 49 Female 195 lb 10/28/2011 Consumer United States
Primary
Concomitant
Condition Aggravated Other Serious 1/1/2008 36 Female 218 lb 10/20/2011 Pharmacist United States
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 10/31/2011 64 Male 285 lb 11/28/2011 Physician United States
Primary
Secondary
Concomitant
Impaired Driving Ability Other Serious 2/1/2011 61 Female 152 lb 11/30/2011 Consumer United States
Primary
Concomitant
Chest Discomfort Hospitalization 10/31/2011 64 Male 285 lb 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral 5/1/2011 69 108 lb 12/13/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 10/31/2011 64 Male 285 lb 12/19/2011 Physician United States
Primary
Secondary
Concomitant
Lower Limb Fracture Other Serious 10/23/2011 53 Female 12/8/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 10/1/2010 61 Female 152 lb 1/4/2012 Physician United States
Primary
Concomitant
Tachycardia Death 2/9/2006 40 Female 1/14/2012 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/1/2010 61 Female 152 lb 1/27/2012 Physician United States
Primary
Concomitant
Asthenia 6/21/2011 48 Female 1/28/2012 Consumer United States
Primary
Concomitant
Dysarthria Hospitalization 10/1/2003 55 Male 185 lb 1/30/2012 Lawyer United States
Primary
Concomitant
Metastases To Lung Other Serious Female 2/7/2012 United States
Primary
Secondary
Concomitant
Pain Other Serious 7/1/2009 38 Male 215 lb 1/25/2012 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Exertional Other Serious 7/1/2009 38 Male 186 lb 1/30/2012 Physician United States
Primary
Secondary
Concomitant
Therapeutic Product Ineffective Required Intervention 8/30/2010 80 Male 260 lb 2/9/2012 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Male 2/24/2012 Pharmacist United States
Primary
Concomitant
Injection Site Reaction Hospitalization 11/1/2010 42 Female 243 lb 3/1/2012 Physician United States
Primary
Concomitant
Chest Discomfort Other Serious 3/7/2010 58 Female 3/5/2012 Physician Canada
Primary
Concomitant
Aphasia Other Serious 2/20/2012 74 Female 165 lb 3/15/2012 Physician Germany
Primary
Concomitant
Thrombosis Other Serious 2/1/2012 50 Male 275 lb 3/16/2012 Consumer United States
Primary
Concomitant
Overweight Other Serious 10/11/2009 48 Male 276 lb 3/16/2012 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 2/1/2012 50 Male 376 lb 3/20/2012 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/23/2012 47 Female 342 lb 1/26/2012 Pharmacist United States
Primary
Concomitant
Influenza Other Serious 3/7/2010 58 Female 3/28/2012 Physician Canada
Primary
Concomitant
Overweight Other Serious 10/11/2009 48 Male 276 lb 4/10/2012 Consumer United States
Primary
Concomitant
Overweight Other Serious 10/11/2009 48 Male 276 lb 4/18/2012 Consumer United States
Primary
Concomitant
Abasia Other Serious 2/1/2012 50 Male 375 lb 4/19/2012 Physician United States
Primary
Concomitant
Pain 4/1/2012 47 Male 5/9/2012 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 1/6/2011 45 Female 250 lb 5/17/2012 Physician United States
Primary
Concomitant
Fatigue Death 5/2/2012 50 Male 5/18/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 5/2/2012 50 Male 5/21/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Blood Glucose Fluctuation Other Serious 3/7/2010 58 Female 5/22/2012 Consumer Canada
Primary
Concomitant
Nodule Other Serious Female 165 lb 5/22/2012 Physician United States
Primary
Concomitant
Multiple Drug Overdose Intentional Hospitalization 5/2/2012 50 Male 5/23/2012 Other Health Professional Germany
Primary
Secondary
Nodule Other Serious 3/30/2012 61 Female 165 lb 5/30/2012 Consumer United States
Primary
Concomitant
Fatigue Death 5/2/2012 50 Male 6/1/2012 Other Health Professional Germany
Primary
Secondary
Suicide Attempt Hospitalization 5/2/2012 50 Male 6/1/2012 Other Health Professional Germany
Primary
Secondary
Fatigue Hospitalization 5/2/2012 50 Male 6/5/2012 Other Health Professional Germany
Primary
Secondary
Dissociation Other Serious 28 Male 6/12/2012 Other Health Professional United States
Primary
Secondary
Suicide Attempt Hospitalization 5/2/2012 50 6/4/2012 Other Health Professional Germany
Primary
Secondary
Dizziness Other Serious 1/6/2011 45 Female 250 lb 6/15/2012 Physician United States
Primary
Concomitant
Cholecystitis Infective Hospitalization 6/5/2012 55 Female 180 lb 7/3/2012 Physician United States
Primary
Concomitant
Anxiety Other Serious 59 Male 196 lb 7/20/2012 Consumer United States
Primary
Concomitant

Drug Data