Lisinopril combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperglycaemia Other Serious 4/1/2004 86 Female 1/5/2006 Other Health Professional Canada
Primary
Concomitant
Weight Increased Hospitalization 11/15/2005 71 Male 249 lb 1/17/2006 Physician Germany
Primary
Concomitant
Dyspnoea Hospitalization 10/27/2005 Male 299 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 10/17/2005 80 Male 194 lb 10/20/2005 Pharmacist United States
Primary
Secondary
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Renal Impairment Required Intervention 3/1/2005 49 Female 2/1/2006 Physician United States
Primary
Concomitant
Urticaria Other Serious 1/10/2006 52 Female 220 lb 2/1/2006 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Life Threatening 11/22/2005 65 Male 298 lb 11/28/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 12/7/2005 84 Male Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 68 Female 2/10/2006 United States
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2003 57 Male 201 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 1/1/2003 57 Male 201 lb 2/27/2006 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Death 12/24/2005 57 Male 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Death 1/18/2006 85 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Chronic Life Threatening 7/1/2004 81 Male 224 lb 3/2/2006 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 1/26/2006 64 Male 3/3/2006
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/26/2006 64 Male 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/26/2006 64 Male 3/7/2006 United Kingdom
Primary
Secondary
Concomitant
Urosepsis Death 1/28/2005 29 Male 126 lb 3/24/2006 Physician Austria
Primary
Concomitant
Rash Generalised 12/10/2005 40 Female 1/30/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/4/2003 63 Female 154 lb 4/10/2006 Lawyer United States
Primary
Concomitant
Malignant Neoplasm Progression Death 12/24/2005 57 Male 4/11/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 6/1/2003 49 Female 4/17/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/28/2006 60 Male 212 lb 4/13/2006 Physician United States
Primary
Concomitant
Neck Pain Death 2/16/2006 82 Male 205 lb 4/4/2006 Consumer United States
Primary
Concomitant
Urticaria Other Serious 1/2/2006 67 Male 248 lb 2/15/2006 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 11/26/2003 56 Female 4/24/2006 Physician United States
Primary
Concomitant
Epistaxis Hospitalization 2/2/2006 54 Female 179 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 8/1/2000 55 Male 2/23/2006 United States
Primary
Concomitant
Road Traffic Accident Other Serious 3/20/2006 61 Female 4/24/2006 United States
Primary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 4/25/2006 United States
Primary
Concomitant
Urosepsis Death 29 Male 126 lb 5/4/2006 Physician Austria
Primary
Concomitant
Oedema Peripheral Other Serious 73 Male 5/5/2006 Physician United Kingdom
Primary
Secondary
Ocular Hyperaemia Required Intervention 4/17/2006 Male 188 lb 5/10/2006 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 2/2/2006 83 Male Pharmacist United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 68 Male 5/23/2006 United States
Primary
Secondary
Concomitant
Medication Error Hospitalization 8/1/2000 68 Female 5/24/2006 Consumer United States
Primary
Secondary
Concomitant
Lipase Increased Hospitalization 5/4/2006 62 Male 5/22/2006 Physician United States
Primary
Concomitant
Renal Failure Chronic Required Intervention 12/22/2005 Male 243 lb 2/14/2006 Pharmacist United States
Primary
Secondary
Cardiac Failure Other Serious 73 Male 5/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Rales Other Serious 73 Male 6/1/2006 Consumer United Kingdom
Primary
Secondary
Rash Maculo-papular Hospitalization 3/28/2006 65 Male 307 lb 4/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis 2/19/2006 84 Male 5/24/2006 Switzerland
Primary
Secondary
Concomitant
Nervousness 6/1/2005 69 Female 139 lb 6/8/2006 Consumer United States
Primary
Concomitant
Rash Maculo-papular Other Serious 6/7/2006 66 Female 150 lb 6/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 12/7/2001 56 Male 6/13/2006 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 73 Male 6/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Cardiac Failure Other Serious 1/1/2000 73 Male 6/12/2006 United Kingdom
Primary
Secondary
Pulmonary Fibrosis Other Serious 8/1/2000 55 Male 2/23/2006 United States
Primary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 7/6/2006 United States
Primary
Concomitant
Myalgia Disability 6/19/2006 49 Male 186 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 5/2/2006 68 Female 126 lb 7/10/2006 Physician United States
Primary
Secondary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Skin Lesion Hospitalization 3/2/2006 41 Male 214 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Muscle Spasms 68 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Visual Disturbance 11/1/2005 77 Male 7/21/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/4/2006 Male 217 lb 5/5/2006 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Hospitalization 4/2/2006 Male 192 lb 5/10/2006 Pharmacist United States
Primary
Secondary
Renal Failure Hospitalization 6/25/2006 66 Male 248 lb 6/25/2006 Pharmacist United States
Primary
Secondary
Sepsis Hospitalization 6/13/2006 Male 102 lb 7/28/2006 United States
Primary
Concomitant
Skin Lesion Hospitalization 3/2/2006 41 Male 214 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Alopecia Female 8/1/2006 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 3/23/2006 84 Male 174 lb 6/9/2006 Pharmacist United States
Primary
Secondary
Sepsis Hospitalization 6/13/2006 Male 102 lb 8/9/2006 United States
Primary
Concomitant
Arrhythmia Other Serious 6/14/2006 67 Male 8/4/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/26/2006 64 Male 8/8/2006 Denmark
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2006 68 Male 8/17/2006 United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 11/7/2005 33 Female 8/15/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 71 Female 155 lb 8/22/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 7/6/2006 79 Male 171 lb 7/6/2006 Pharmacist United States
Primary
Secondary
Petechiae Hospitalization 8/4/2006 73 159 lb 8/29/2006 Physician Germany
Primary
Concomitant
Haemoptysis Other Serious 6/9/2006 78 Male 170 lb 8/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 6/13/2006 Male 102 lb 9/1/2006 United States
Primary
Concomitant
Weight Decreased 3/1/2006 62 Female 244 lb 7/19/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/28/2006 54 Male 9/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thirst 63 Male 355 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Hospitalization 1/1/1982 51 Female 9/29/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/3/2006 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 9/27/2006 62 Male 230 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/5/2006
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/5/2006 Physician United States
Primary
Secondary
Concomitant
Sedation Other Serious 8/7/2006 97 Male 135 lb 9/25/2006 Other Health Professional United States
Primary
Concomitant
Ill-defined Disorder Hospitalization 7/7/2006 82 Male 192 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mania Other Serious 9/26/2006 Female 10/11/2006 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 1/1/1997 Female 10/11/2006 Consumer United States
Primary
Concomitant
Headache Other Serious 1/1/2005 86 Male 165 lb 10/5/2006 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/2/2006 85 Male 10/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/9/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Required Intervention 78 Male 10/10/2006 Other Health Professional Denmark
Primary
Concomitant
Vasoconstriction Hospitalization 9/18/2006 53 Female 10/25/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/14/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 9/30/2006 60 Female 10/9/2006 Consumer United States
Primary
Concomitant
Mania Other Serious 3/1/2006 Female 10/31/2006 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 9/25/2006 71 Male 165 lb 9/29/2006 Pharmacist United States
Primary
Secondary
Tachycardia Hospitalization 9/26/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/29/2006 64 Female 11/1/2006 Consumer United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 10/12/2006 73 Female 10/26/2006 United States
Primary
Concomitant
Linear Iga Disease Other Serious 73 Male 10/26/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 76 Female 11/7/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Petechiae Hospitalization 8/4/2006 73 159 lb 11/10/2006 Physician Germany
Primary
Concomitant
Tachycardia Other Serious 1/1/2006 69 Female 11/13/2006 Consumer United States
Primary
Concomitant
Drug Administration Error Male 11/13/2006 Consumer United States
Primary
Concomitant
Skin Discolouration 57 Male 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Alopecia 2/1/2005 68 Male 11/13/2006 Consumer United States
Primary
Secondary
Therapeutic Response Unexpected 10/10/2002 63 Male 11/13/2006 Consumer United States
Primary
Concomitant
Alopecia 10/1/2005 73 Female 11/13/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/1/2005 52 Male 11/13/2006 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious Female 11/13/2006 Consumer United States
Primary
Concomitant
Palpitations 5/5/2006 65 Female 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 73 Female 11/6/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 76 Female 11/14/2006 Physician Canada
Primary
Secondary
Concomitant
Vision Blurred Other Serious Male 250 lb 11/8/2006 United States
Primary
Secondary
Concomitant
Dizziness Required Intervention 10/20/2006 83 Male 144 lb 11/1/2006 Other Health Professional United States
Primary
Concomitant
Speech Disorder Other Serious 7/21/2006 86 Male 164 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 8/2/2006 65 Male 185 lb 9/18/2006 Physician United States
Primary
Concomitant
Lip Swelling Required Intervention 4/18/2006 50 Male 4/18/2006 Physician United States
Primary
Concomitant
Malaise 11/21/2006 83 Female 220 lb 11/22/2006 Other Health Professional United States
Primary
Concomitant
Thirst Hospitalization 11/1/2006 62 97 lb 12/1/2006 Pharmacist United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 11/27/2006 59 Male 223 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Skin Necrosis Hospitalization 7/1/2003 75 Female 11/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 11/30/2006 55 Male 197 lb 12/4/2006 Pharmacist United States
Primary
Secondary
Vision Blurred Other Serious Male 250 lb 12/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise 83 Female 220 lb 12/21/2006 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 9/30/2006 60 Female 1/8/2007 Consumer United States
Primary
Concomitant
Post Procedural Complication Hospitalization 1/1/2006 62 Female 200 lb 1/9/2007 Consumer United States
Primary
Concomitant
Vomiting 1/1/2006 36 Female 216 lb 10/24/2006 United States
Primary
Concomitant
Adverse Event Disability 8/28/2006 Male 138 lb 12/13/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/20/2006 81 Male 1/18/2007
Primary
Secondary
Concomitant
Urine Sodium Increased Hospitalization 78 Male 1/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 4/14/2006 80 Male 240 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Rash Other Serious 10/24/2006 56 Male 210 lb 10/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Gynaecomastia Other Serious 9/26/2006 64 Male 242 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Subdural Haematoma Life Threatening 10/18/2006 80 Male 191 lb 1/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/20/2006 81 Male 1/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 78 Male 1/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 78 Male 1/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Subdural Haemorrhage Hospitalization 1/19/2007 66 Male 1/26/2007 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/10/2006 Male 215 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 7/12/2006 75 Female 160 lb 8/17/2006 United States
Primary
Concomitant
Vomiting Other Serious 12/1/2006 Male 169 lb 2/14/2007 Other Health Professional United States
Primary
Concomitant
Proteinuria Disability 1/9/2007 52 Female 262 lb 3/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tendonitis Other Serious 1/20/2006 64 Female 94 lb 10/23/2006 Physician United States
Primary
Concomitant
Fatigue Hospitalization 1/17/2007 70 Female 159 lb 3/19/2007 Consumer United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 1/1/2006 62 Female 198 lb 3/19/2007 Consumer United States
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 8/9/2004 46 Female 173 lb 11/27/2006 United States
Primary
Concomitant

Drug Data