Lisinopril combined with Sorafenib

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vision Blurred Hospitalization 8/9/2005 57 Male 272 lb 1/10/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 1/18/2006 54 Male 262 lb 1/25/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 1/18/2006 54 Male 262 lb 2/1/2006 Physician United States
Primary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/8/2006 United States
Primary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/10/2006 United States
Primary
Concomitant
Small Intestine Carcinoma Metastatic Other Serious 12/30/2005 63 Male 2/15/2006 Physician United States
Primary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/20/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/30/2005 63 Male 2/17/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/3/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/8/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/15/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/30/2005 63 Male 3/23/2006 United States
Primary
Concomitant
Tumour Invasion Other Serious 12/30/2005 63 Male 3/27/2006 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 3/8/2006 77 Female 170 lb 4/17/2006 Physician United States
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Other Serious 3/8/2006 77 Female 170 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Hypertension Hospitalization 6/18/2005 73 Female 131 lb 4/19/2006 Physician United States
Primary
Concomitant
Metastases To Lung Hospitalization 6/18/2005 73 Female 131 lb 4/21/2006 Physician United States
Primary
Concomitant
Peptic Ulcer Haemorrhage Life Threatening 5/7/2006 54 Male 143 lb 5/16/2006 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 2/15/2006 77 Female 170 lb 5/17/2006 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 2/9/2006 62 Male 155 lb 5/30/2006 Consumer United States
Primary
Concomitant
Nausea Life Threatening 5/7/2006 54 Male 143 lb 5/26/2006 United States
Primary
Concomitant
Vomiting Hospitalization 7/13/2005 79 Female 179 lb 6/8/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 5/8/2006 54 Male 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 5/8/2006 54 Male 6/13/2006 United States
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 6/9/2006 76 Female 126 lb 7/5/2006 United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 2/15/2006 77 Female 177 lb 7/20/2006 Physician United States
Primary
Secondary
Concomitant
Sarcoidosis Hospitalization 56 Female 7/31/2006 Consumer Germany
Primary
Secondary
Concomitant
Convulsion Hospitalization 6/9/2006 77 Female 126 lb 8/29/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 9/12/2006 Physician United States
Primary
Concomitant
Sarcoidosis Disability 7/14/2006 56 Female 9/14/2006 Physician Germany
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 7/11/2005 77 Male 143 lb 9/19/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/30/2005 63 Male 9/26/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 5/7/2006 54 Male 143 lb 10/3/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/30/2005 63 Male 148 lb 10/4/2006 Physician United States
Primary
Concomitant
Pulmonary Mass Hospitalization 6/9/2006 77 Female 126 lb 10/6/2006 Physician United States
Primary
Concomitant
Sarcoidosis Hospitalization 4/16/2006 56 Female 10/6/2006 Physician Germany
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 5/7/2006 54 Male 143 lb 10/9/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/30/2005 63 Male 148 lb 10/11/2006 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 2/9/2006 63 Male 154 lb 10/11/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Hospitalization 6/9/2006 77 Female 126 lb 10/16/2006 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 9/13/2005 53 Male 143 lb 10/17/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/30/2005 63 Male 148 lb 10/17/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 5/27/2006 50 Male 198 lb 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2006 70 Male 225 lb 10/30/2006 Physician Canada
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 2/9/2006 63 Male 154 lb 11/2/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 12/30/2005 63 Male 148 lb 11/3/2006 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 2/9/2006 63 Male 154 lb 11/7/2006 Physician United States
Primary
Concomitant
Productive Cough Other Serious 11/1/2005 71 Male 240 lb 11/8/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/27/2006 50 Male 198 lb 11/17/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/1/2005 69 Male 130 lb 11/21/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 1/18/2006 55 Male 262 lb 11/22/2006 Physician United States
Primary
Concomitant
Splenomegaly Hospitalization 5/27/2006 50 Male 198 lb 11/29/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/13/2005 79 Female 179 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/9/2005 57 Male 271 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2006 70 Male 225 lb 12/5/2006 Physician Canada
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/9/2005 57 Male 271 lb 12/6/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2005 69 Male 130 lb 12/7/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/13/2005 79 Female 179 lb 12/8/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2005 69 Male 130 lb 12/12/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 3/29/2006 49 Male 198 lb 12/15/2006 Physician United States
Primary
Secondary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 9/10/2005 53 Male 143 lb 12/29/2006 Physician United States
Primary
Concomitant
Dry Skin Male 11/6/2006 United States
Primary
Concomitant
Respiratory Failure Other Serious 12/30/2005 63 Male 148 lb 1/24/2007 Physician United States
Primary
Concomitant
Confusional State Hospitalization 11/20/2006 54 Male 212 lb 2/6/2007 Physician Netherlands
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/20/2006 54 Male 212 lb 2/26/2007 Physician Netherlands
Primary
Secondary
Concomitant
Skin Ulcer Disability 7/18/2006 56 Female 2/26/2007 Physician Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 2/5/2007 73 Male 143 lb 2/28/2007 Physician Germany
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 9/10/2006 66 Male 132 lb 2/28/2007 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 9/10/2006 66 Male 132 lb 3/7/2007 Physician Germany
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 4/28/2006 70 Male 225 lb 3/8/2007 Physician Canada
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/20/2006 54 Male 212 lb 3/12/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/22/2007 75 Male 168 lb 3/16/2007 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2005 69 Male 130 lb 4/12/2007 Physician United States
Primary
Concomitant
Tumour Haemorrhage Hospitalization 11/11/2005 67 Male 194 lb 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/13/2005 79 Female 179 lb 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Disability 7/18/2006 56 Female 4/20/2007 Physician Germany
Primary
Secondary
Concomitant
Metastases To Meninges Other Serious 1/11/2007 46 Male 229 lb 4/26/2007 Pharmacist United States
Primary
Concomitant
Dyspnoea Hospitalization 11/20/2006 54 Male 212 lb 5/3/2007 Physician Netherlands
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 7/16/2007 58 Male 191 lb 7/18/2007 United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 4/28/2006 70 Male 225 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/14/2004 Female 8/20/2007 Pharmacist United States
Primary
Concomitant
Electrocardiogram St Segment Elevation Hospitalization 1/2/2007 43 Female 10/25/2007 United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 1/2/2007 43 Female 10/29/2007 United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 1/2/2007 43 Female 209 lb 11/7/2007 United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 1/2/2007 43 Female 209 lb 11/12/2007 United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 1/2/2007 43 Female 209 lb 11/20/2007 United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 1/2/2007 43 Female 209 lb 11/27/2007 United Kingdom
Primary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 4/28/2006 70 Male 225 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/22/2008 80 Male 158 lb 3/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/22/2008 80 Male 158 lb 4/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/22/2008 80 Male 158 lb 4/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 4/23/2008 Male 4/24/2008 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 5/2/2008 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 3/13/2008 64 Male 5/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Migraine With Aura Hospitalization 3/29/2006 49 Male 198 lb 5/27/2008 Physician United States
Primary
Secondary
Concomitant
Migraine With Aura Hospitalization 3/29/2006 49 Male 198 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 1/2/2007 43 Female 209 lb 8/11/2008 United Kingdom
Primary
Concomitant
Urine Output Decreased Hospitalization 5/2/2008 Male 320 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 5/2/2008 Male 320 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Migraine With Aura Hospitalization 3/29/2006 49 Male 198 lb 8/28/2008 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4/24/2008 74 Female 97 lb 9/2/2008 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/20/2007 63 Female 220 lb 10/28/2008 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 10/24/2008 62 Male 234 lb 11/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/29/2008 62 Female 311 lb 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/3/2009 Male 249 lb 2/10/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 2/4/2009 76 Male 159 lb 2/13/2009 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/4/2009 76 Male 159 lb 2/23/2009 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 2/4/2009 76 Male 159 lb 3/4/2009 United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 1/13/2009 Male 249 lb 3/27/2009 Physician United States
Primary
Concomitant
Intestinal Perforation Life Threatening 3/26/2009 40 Female 172 lb 4/6/2009 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 11/18/2008 76 Male 141 lb 4/9/2009 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 4/27/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4/24/2008 74 Female 97 lb 5/1/2009 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Dysplastic Naevus Syndrome Other Serious Male 194 lb 6/24/2009 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/7/2009 United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/1/2009 Male 194 lb 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/31/2009 United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 7/4/2009 Male 193 lb 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 8/6/2009 70 Male 220 lb 8/13/2009 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Abnormal Hospitalization 8/6/2009 70 Male 220 lb 8/21/2009 Physician United States
Primary
Concomitant
Diarrhoea 65 Female 8/25/2009 Other Health Professional United States
Primary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/4/2009 Male 193 lb 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/4/2009 Male 193 lb 9/2/2009 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Other Serious 8/6/2009 70 Male 220 lb 9/3/2009 Physician United States
Primary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/26/2009 40 Female 172 lb 9/18/2009 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/9/2009 77 Male 269 lb 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2009 Male 193 lb 10/15/2009 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 9/9/2009 77 Male 269 lb 11/2/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/15/2009 72 Female 185 lb 11/4/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/15/2009 72 Female 185 lb 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 1/1/2010 Female 2/2/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 2/3/2010 63 Male 2/12/2010 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 2/4/2010 63 Male 2/25/2010 Physician Germany
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 2/26/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/2/2010 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 1/17/2010 55 Male 254 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/11/2010 Physician United States
Primary
Concomitant
Osteomyelitis Hospitalization 6/23/2009 78 Male 168 lb 3/16/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2007 Male 222 lb 3/18/2010 Physician United States
Primary
Concomitant
Infusion Related Reaction Other Serious 1/1/2010 Female 3/24/2010 Physician United States
Primary
Concomitant

Drug Data