Linezolid combined with Vancomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 1/5/2006 United States
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased 7/31/2005 66 141 lb 1/6/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 2/7/2005 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Death 10/7/2004 50 9/12/2005 Physician United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 10/10/2005 Female 10/18/2005 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/5/2004 61 Male 2/7/2006 Physician United States
Primary
Concomitant
Septic Arthritis Staphylococcal Other Serious 64 Female 2/14/2006 Physician United States
Primary
Concomitant
Renal Failure Other Serious 9/18/2005 70 Male 260 lb 2/24/2006 Pharmacist United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 64 Female 2/23/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Enterococcal 56 Female 3/9/2006 United States
Primary
Secondary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Other Serious 3/12/2006 58 Male 4/21/2006 Korea, Republic Of
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 45 Female 165 lb 5/22/2006 Physician United States
Primary
Concomitant
Tongue Black Hairy Death 3/8/2003 91 Male 6/16/2006 Consumer Canada
Primary
Secondary
Concomitant
Tracheal Haemorrhage Hospitalization 5/31/2006 69 Male 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Disability 6/19/2006 49 Male 186 lb 7/12/2006 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 6/9/2006 48 Female 227 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 1/1/2005 23 Male 7/19/2006 Physician United States
Primary
Concomitant
Myalgia 6/8/2006 42 Female 176 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 49 Male 8/7/2006 Physician United States
Primary
Concomitant
Pelvic Pain 7/26/2006 Female 244 lb 8/4/2006 United States
Primary
Secondary
Concomitant
Endocarditis Other Serious 39 Male 180 lb 8/10/2006 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 7/26/2006 Female 244 lb 8/18/2006 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 39 Male 180 lb 8/21/2006 Other Health Professional United States
Primary
Concomitant
Endocarditis Other Serious 39 Male 180 lb 9/27/2006 Other Health Professional United States
Primary
Concomitant
Cataract Disability 8/21/2006 43 Unknown 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 8/4/2006 58 Male 168 lb 8/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombophlebitis Septic Other Serious 1/1/2005 47 Male 10/24/2006 United States
Primary
Concomitant
Pyrexia Other Serious 60 Male 235 lb 10/6/2006 Physician United States
Primary
Concomitant
Tachycardia Required Intervention 8/1/2006 Male 8/7/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Life Threatening 1/3/2007 30 Male 168 lb 1/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/24/2007 30 Male 202 lb 1/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 15 Male 2/28/2007 Physician United States
Primary
Concomitant
Drug Level Decreased Other Serious 31 Female 3/19/2007
Primary
Concomitant
Interacting
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Blood Potassium Increased Life Threatening 4/8/2007 51 Male 5/17/2007 United Kingdom
Primary
Concomitant
Blood Potassium Increased Life Threatening 4/8/2007 51 Male 5/16/2007 United Kingdom
Primary
Concomitant
Retroperitoneal Abscess Hospitalization 11/1/2004 60 Male 207 lb 6/13/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/12/2007 Female 368 lb 8/1/2007 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 6/18/2007 61 Male 8/15/2007 Pharmacist Ireland
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 12/11/2005 Male 9/6/2007 Other Health Professional France
Primary
Secondary
Serotonin Syndrome Hospitalization 23 Male 10/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Postoperative Wound Infection Hospitalization 9/10/2007 Male 183 lb 10/18/2007 Physician Italy
Primary
Concomitant
Postoperative Wound Infection Life Threatening 9/10/2007 Male 183 lb 10/31/2007 Physician Italy
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/1/2007 Other Health Professional Austria
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/2/2007 Other Health Professional Austria
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/2/2007 Other Health Professional Austria
Primary
Concomitant
Thrombocytopenia Hospitalization 5/19/2007 Male 134 lb 11/12/2007 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Other Serious 4/1/2007 51 Male 11/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
Postoperative Wound Infection Life Threatening 9/10/2007 Male 183 lb 11/15/2007 Physician Italy
Primary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 1/1/2007 60 Male 12/26/2007
Primary
Concomitant
Pancytopenia Other Serious 5/10/2005 1 Female 12/31/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/1/2008 68 Male 198 lb 1/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Off Label Use Other Serious 0 7 lb 2/26/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2007 31 Female 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 66 Female 152 lb 3/11/2008 Pharmacist United States
Primary
Secondary
Concomitant
Serotonin Syndrome Required Intervention 27 Male 3/18/2008 Physician Canada
Primary
Secondary
Concomitant
Blood Potassium Increased Required Intervention 1/13/2008 41 Male 331 lb 2/20/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/11/2008 63 Male 243 lb 4/15/2008 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 4/16/2008 22 Male 185 lb 4/22/2008 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 36 Female 5/30/2008 Physician United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/5/2007 70 Male 256 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/5/2007 43 Male 197 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 6/14/2008 Female 172 lb 7/2/2008 Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 70 Male 8/1/2008 Physician United States
Primary
Concomitant
Rash Hospitalization 7/17/2008 73 Female 10/3/2008 Other Health Professional France
Primary
Secondary
Concomitant
Treatment Failure Other Serious 80 Male 10/13/2008 United Kingdom
Primary
Secondary
Multiple-drug Resistance Other Serious 75 Female 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Multiple-drug Resistance Other Serious 80 Male 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Treatment Failure Other Serious 75 Female 10/13/2008 United Kingdom
Primary
Secondary
Multiple-drug Resistance Other Serious 80 Male 10/17/2008 United Kingdom
Primary
Secondary
Multiple-drug Resistance Other Serious 75 Female 10/17/2008 United Kingdom
Primary
Secondary
Treatment Failure Other Serious 80 Male 10/24/2008 United Kingdom
Primary
Secondary
Treatment Failure Other Serious 75 Female 10/24/2008 United Kingdom
Primary
Secondary
Urine Output Decreased Death 59 Male 10/31/2008 Physician Taiwan, Province Of China
Primary
Concomitant
Surgery Other Serious 75 Female 10/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Anaphylactic Reaction Life Threatening 2/14/2008 Female 326 lb 10/27/2008 Physician United States
Primary
Concomitant
Renal Failure Other Serious 5/30/2008 Male 10/27/2008 Physician United States
Primary
Concomitant
Drug Resistance Other Serious 80 Male 11/24/2008 United Kingdom
Primary
Secondary
Drug Resistance Other Serious 75 Female 11/24/2008 United Kingdom
Primary
Secondary
Neutropenia Hospitalization 11/23/2008 Male 134 lb 11/25/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 56 Female 12/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ileus Other Serious 60 Male 12/16/2008
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/23/2008 1/5/2009 Physician Chile
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 56 Female 12/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 58 Female 1/9/2009 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/9/2008 1/16/2009 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 11/28/2008 Female 163 lb 2/4/2009 Germany
Primary
Secondary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 58 Female 2/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Aspartate Aminotransferase Increased Required Intervention Female 3/3/2009 Ireland
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 3/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Failure Other Serious 11/23/2008 3/24/2009 Physician Chile
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/3/2009 44 Female 110 lb 3/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/24/2009 Physician Japan
Primary
Concomitant
Status Epilepticus Life Threatening 1/8/2009 77 Male 6/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 55 Female 6/22/2009 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 58 Female 6/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 9/12/2004 Female 125 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Somnolence Required Intervention 3/26/2009 49 Male 170 lb 5/8/2009 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Other Serious 6/28/2009 87 7/10/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Ischaemic Hepatitis Other Serious 10/2/2008 82 Female 167 lb 7/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple-drug Resistance Other Serious 42 Male 8/19/2009 United Kingdom
Primary
Concomitant
Treatment Failure Other Serious 42 Male 8/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Staphylococcal Other Serious 79 Male 8/24/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 79 Male 9/1/2009 United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 5/24/2008 53 Male 9/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Weaning Failure Hospitalization 79 Male 9/12/2009 Physician United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 88 9/22/2009 Other Health Professional Canada
Primary
Concomitant
Treatment Failure Other Serious 42 Male 10/8/2009 United Kingdom
Primary
Concomitant
Treatment Failure Other Serious 80 Male 10/8/2009 United Kingdom
Primary
Concomitant
Treatment Failure Other Serious 75 Female 10/8/2009 United Kingdom
Primary
Concomitant
Traumatic Liver Injury Other Serious 10/2/2008 82 Female 167 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 11/23/2008 68 Female 165 lb 11/26/2009 Physician Chile
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 7 Male 11/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/1/2009 72 Female 160 lb 12/21/2009 Physician United States
Primary
Concomitant
Hyponatraemia Other Serious 6/14/2009 62 Female 1/29/2010 Consumer United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 41 Male 2/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 10/5/2009 43 Male 2/18/2010 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 2/7/2009 Female 121 lb 2/24/2010 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/7/2009 Female 121 lb 3/4/2010 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Liver Abscess Hospitalization 21 Male 2/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/28/2009 66 Male 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 60 Female 4/1/2010 Physician Japan
Primary
Concomitant
Subcutaneous Abscess Other Serious 60 Female 4/2/2010 Physician Japan
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 60 Female 4/8/2010 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 60 Female 4/8/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 10/20/2009 82 Male 126 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/7/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 6/26/2003 54 Female 4/15/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/28/2009 66 Male 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Abnormal Other Serious 79 Male 4/21/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 6/26/2003 54 Female 4/23/2010 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
Sepsis Other Serious 3/23/2010 65 Male 226 lb 5/17/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 3/23/2010 65 Male 5/17/2010 Other Health Professional United States
Primary
Secondary
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/28/2009 66 Male 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data