Linezolid combined with Metronidazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/2/2004 65 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 45 Male 3/27/2006 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 4/18/2006 Physician Germany
Primary
Concomitant
Serotonin Syndrome Other Serious 45 Male 4/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/5/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/8/2006 Physician Germany
Primary
Concomitant
Subcutaneous Haematoma Life Threatening 2/21/2006 66 Female 5/8/2006 Physician Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 45 Female 165 lb 5/22/2006 Physician United States
Primary
Concomitant
Insomnia Other Serious 5/2/2006 Male 441 lb 5/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 6/7/2006 Physician Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2006 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vena Cava Thrombosis Death 46 Female 110 lb 9/5/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening 9/18/2006 69 Male 198 lb 10/16/2006 Physician Germany
Primary
Concomitant
Tumour Haemorrhage Life Threatening 9/18/2006 69 Male 198 lb 10/19/2006 Physician Germany
Primary
Concomitant
Renal Failure Life Threatening 9/18/2006 69 Male 198 lb 10/23/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/18/2006 69 Male 198 lb 10/27/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/18/2006 69 Male 198 lb 11/1/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/3/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/15/2006 Physician Germany
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 11/27/2006 Physician Germany
Primary
Concomitant
Therapy Non-responder Life Threatening 11/18/2006 58 Female 142 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 12/4/2006 Physician Germany
Primary
Concomitant
Staphylococcal Infection Other Serious 9/14/2006 26 Male 11/27/2006 Physician Spain
Primary
Secondary
Concomitant
Tachycardia Required Intervention 8/1/2006 Male 8/7/2006 Pharmacist United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 1/12/2007 Physician Germany
Primary
Concomitant
Paraesthesia Other Serious 9/1/2006 76 Female 134 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 3/13/2007 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 3/7/2007 81 Male 163 lb 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/1/2007 Physician Germany
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/24/2005 44 Female 5/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/11/2007 Physician Germany
Primary
Concomitant
Septic Shock Life Threatening 9/1/2006 69 Male 198 lb 5/22/2007 Physician Germany
Primary
Concomitant
Rhabdomyolysis Other Serious 1/12/2007 57 Male 401 lb 4/30/2007 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 12/1/2005 25 Male 7/20/2007 Spain
Primary
Concomitant
Haemorrhage Required Intervention 7/8/2007 59 Male 209 lb 7/18/2007 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 4/19/2007 Female 165 lb 4/24/2007 Pharmacist United States
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Required Intervention 8/23/2007 43 Female 104 lb 10/4/2007 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 21 Male 12/3/2007 Other Health Professional Greece
Primary
Secondary
Vomiting Life Threatening 1/1/2008 68 Male 198 lb 1/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 70 Male 8/1/2008 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 3/20/2008 62 Male 154 lb 8/13/2008 Pharmacist United States
Primary
Concomitant
Pustular Psoriasis Other Serious 9/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious 9/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious 9/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 9/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 30 Female 159 lb 9/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 8/18/2008 48 Male 243 lb 10/1/2008 United States
Primary
Concomitant
Renal Failure Other Serious 5/30/2008 Male 10/27/2008 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 11/23/2008 1/5/2009 Physician Chile
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/23/2008 1/20/2009 Physician Chile
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/23/2008 1/22/2009 Physician Chile
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 11/24/2008 3/12/2009 Other Health Professional Spain
Primary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Deafness Neurosensory Hospitalization 51 Female 3/26/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 11/23/2008 3/24/2009 Physician Chile
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 6/14/2008 3/31/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/23/2008 4/7/2009 Physician Chile
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 11/24/2008 4/29/2009 Other Health Professional Spain
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/12/2004 Female 125 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Somnolence Required Intervention 3/26/2009 49 Male 170 lb 5/8/2009 Pharmacist United States
Primary
Concomitant
Transplant Rejection Other Serious 1/1/2007 64 Female 7/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2009 36 Female 183 lb 9/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 64 Female 11/30/2009
Primary
Secondary
Septic Shock Other Serious 11/23/2008 68 Female 165 lb 11/26/2009 Physician Chile
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Hypotension Death Female 5/21/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Test Positive Hospitalization 54 Male 6/30/2010 Spain
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1/1/2008 58 Male 8/11/2010 Physician Greece
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged 7/21/2010 Female 13 lb 8/23/2010 Pharmacist United States
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/18/2010 61 Female 9/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/18/2010 61 Female 9/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 6/26/2003 54 Female 11/10/2010 United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Upper Airway Obstruction Required Intervention 5/1/2007 48 Female 180 lb 12/14/2010 Consumer United States
Primary
Concomitant
Death Death 82 Female 132 lb 1/7/2011 Physician Greece
Primary
Secondary
Death Death 83 Male 176 lb 1/14/2011 Physician Greece
Primary
Secondary
Glomerular Filtration Rate Decreased Other Serious 12/1/2010 62 Male 1/24/2011 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Death 4/17/2010 34 Female 2/2/2011 Physician Malaysia
Primary
Concomitant
Ankle Fracture Hospitalization 12/17/2010 84 Female 216 lb 2/23/2011 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Granuloma Other Serious 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Stem Cell Transplant Death 9/8/2009 64 Male 217 lb 3/17/2011 Physician United States
Primary
Concomitant
Nausea Other Serious 56 Male 5/3/2011 Pharmacist United States
Primary
Secondary
Concomitant
Nausea Other Serious 56 Male 5/4/2011 Pharmacist United States
Primary
Secondary
Concomitant
Interacting
Unevaluable Event Hospitalization 10/11/2005 80 Female 121 lb 5/6/2011 Consumer United States
Primary
Concomitant
Strabismus Other Serious 56 Male 5/9/2011 Pharmacist United States
Primary
Secondary
Concomitant
Optic Neuropathy Other Serious 6 Male 5/19/2011 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 6 Male 6/28/2011 Other Health Professional United States
Primary
Concomitant
Arthralgia Other Serious 1/1/2006 57 Female 8/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Thrombocytopenia Disability 8/5/2011 49 Male 8/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paranoia Disability 8/5/2011 49 Male 8/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Behaviour Disability 8/5/2011 49 Male 8/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aggression Disability 8/5/2011 49 Male 8/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Behaviour Other Serious 8/5/2011 49 Male 9/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 5/16/2011 8 Female 49 lb 9/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis 3/21/2011 52 Male 194 lb 9/6/2011 Pharmacist United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Disability 8/5/2011 49 Male 8/26/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/1/2011 8 Female 49 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/18/2012 53 Male 3/29/2012 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/2/2011 68 Male 4/6/2012 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/2/2011 68 Male 5/4/2012 Physician Canada
Primary
Secondary
Concomitant
Pneumonitis Other Serious 1/18/2012 53 Male 5/24/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Muscle Weakness Other Serious 56 Female 6/29/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystitis Death Male 6/29/2012 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 7/1/2010 50 Male 128 lb 7/3/2012 Pharmacist China
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 10/1/2010 55 Female 7/18/2012 Other Health Professional United States
Primary
Secondary
Clostridial Infection Hospitalization Female 7/5/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 10/1/2010 56 Female 7/24/2012 Other Health Professional United States
Primary
Secondary
Mental Status Changes Other Serious 50 Female 7/16/2012 Other Health Professional United States
Primary
Secondary
Intestinal Dilatation Other Serious 56 Female 7/19/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Colectomy Total Hospitalization 10/1/2010 56 Female 8/21/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 2011 8 Female 49 lb 10/29/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Venoocclusive Disease Death 8 Female 49 lb 6/27/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 56 Female 8/30/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Cholestasis Disability 10/1/2012 51 Male 227 lb 10/15/2012 Us
Primary
Concomitant
Surgery Death 11/5/2012 Other Health Professional De
Primary
Secondary
Pneumonia Hospitalization 12/31/2012 59 Male 173 lb 1/24/2013 Physician Us
Primary
Concomitant
Arrhythmia Death 76 Male 1/24/2013 Other Health Professional It
Primary
Concomitant
Product Contamination Life Threatening 2/13/2013 54 Female 201 lb 3/12/2013 Pharmacist Us
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 2/13/2013 54 Female 201 lb 3/12/2013 Pharmacist Us
Primary
Secondary
Concomitant
Sepsis Other Serious 2/12/2013 54 Female 3/22/2013 Pharmacist Us
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 84 Female 4/15/2013 Physician Gb
Primary
Secondary
Concomitant
Wound Haemorrhage Hospitalization 1 Male 4/26/2013 Physician Gr
Primary
Secondary
Unresponsive To Stimuli Other Serious 58 Female 4/26/2013 Other Health Professional Nl
Primary
Secondary
Septic Shock Other Serious 53 Female 5/28/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 1/10/2013 19 Male 7/9/2013 Physician Au
Primary
Secondary
Concomitant
Respiratory Failure Death 58 Female 7/22/2013 Physician Nl
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 2013 12 Male 159 lb 7/23/2013 Us
Primary
Secondary
Concomitant
Swelling Life Threatening 58 Female 7/26/2013 Us
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious NotSpecified 8/6/2013 Physician Nl
Primary
Secondary
Concomitant
Multi-organ Failure Death 58 Female 8/6/2013 Physician Nl
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 84 Female 8/2/2013 Gb
Primary
Secondary
Concomitant
Respiratory Failure Death 58 Female 8/6/2013 Physician Nl
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 58 Female 8/8/2013 Physician Nl
Primary
Secondary
Concomitant

Drug Data