Lidocaine combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Delayed Recovery From Anaesthesia 6/17/2005 Female 1/24/2006 Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 24 Male 2/24/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Death 30 Male 161 lb 3/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 74 Female 4/5/2006 Physician France
Primary
Secondary
Neuromuscular Block Prolonged Required Intervention 12/5/2005 34 Female 160 lb 12/5/2005 Physician United States
Primary
Concomitant
Respiratory Failure 3/15/2006 37 Female 4/12/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 30 Male 161 lb 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
Hypotension Other Serious 74 Female 110 lb 4/20/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 7/14/2004 Male 143 lb 5/3/2006 Other Health Professional Japan
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/31/2006 41 Female 163 lb 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 74 Female 110 lb 6/29/2006 Physician Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 8/7/2006 Other Health Professional Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 9/18/2006 Other Health Professional Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 127 lb 10/23/2006 Other Health Professional Japan
Primary
Concomitant
Movement Disorder Disability 88 Female 141 lb 11/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactoid Reaction 32 Female 11/7/2006 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Shock 73 Female 11/9/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 29 Female 11/22/2006 Japan
Primary
Secondary
Concomitant
Spinal Column Stenosis Disability 88 Female 141 lb 11/28/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Procedural Complication 32 Female 11/15/2006 Japan
Primary
Concomitant
Tracheomalacia Other Serious 66 Female 106 lb 11/17/2006 Physician Japan
Primary
Secondary
Urticaria Other Serious 5/2/2006 32 Female 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Erythema Life Threatening 5/2/2006 32 Female 11/29/2006 Japan
Primary
Secondary
Concomitant
Blood Pressure Systolic Decreased Life Threatening 5/2/2006 32 Female 11/24/2006 Japan
Primary
Concomitant
Ruptured Ectopic Pregnancy Hospitalization 11/26/2006 36 Female 153 lb 12/11/2006 United States
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 79 Female 110 lb 1/17/2007 Physician United States
Primary
Concomitant
Interacting
Pulmonary Oedema Death 45 Female 2/1/2007 Physician Lebanon
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 45 Female 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypokinesia Death 45 Female 2/20/2007 Physician Lebanon
Primary
Secondary
Concomitant
Tracheostomy 11 Male 3/12/2007 Japan
Primary
Concomitant
Haemolytic Uraemic Syndrome Hospitalization 3/14/2007 68 Male 4/12/2007 Other Health Professional Japan
Primary
Secondary
Hyperthermia Malignant Other Serious 4/11/2007 Male 159 lb 4/26/2007 Other Health Professional Japan
Primary
Concomitant
Vitamin K Deficiency Hospitalization 75 Male 115 lb 5/23/2007 Japan
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 79 Female 110 lb 7/11/2007 Physician United States
Primary
Concomitant
Interacting
Torsade De Pointes Other Serious 9/24/2006 62 Female 7/27/2007 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 40 Female 161 lb 7/30/2007 United States
Primary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious 71 Male 123 lb 8/24/2007 Japan
Primary
Concomitant
Respiratory Arrest Life Threatening 6/13/2007 8/30/2007 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 6/13/2007 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 2 Female 32 lb 10/11/2007
Primary
Secondary
Concomitant
Ventricular Arrhythmia Other Serious 13 Female 121 lb 11/14/2007
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 4/2/2007 Male 139 lb 11/16/2007 Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening 45 Male 214 lb 12/5/2007 Japan
Primary
Secondary
Concomitant
Surgery Other Serious 4/19/2007 45 Male 214 lb 3/1/2008 Japan
Primary
Secondary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious 12/21/2004 Male 123 lb 3/7/2008 Japan
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 1 Female 4/2/2008 Other Health Professional United States
Primary
Concomitant
Haematocrit Decreased Hospitalization 7/20/2007 71 Male 5/20/2008 Other Health Professional United States
Primary
Concomitant
Hypoventilation 10/23/2007 71 Male 5/22/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/17/2008 37 Male 5/28/2008 Japan
Primary
Secondary
Concomitant
Hypoventilation 10/23/2007 71 Male 6/13/2008 Japan
Primary
Secondary
Concomitant
Ventricular Arrhythmia Life Threatening 13 Female 121 lb 6/18/2008
Primary
Secondary
Concomitant
Vision Blurred Other Serious 29 Male 7/1/2008 Physician Mexico
Primary
Concomitant
Diplegia Disability 88 Female 141 lb 9/15/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 6/27/2008 8 Male 35 lb 8/8/2008 Pharmacist United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Joint Dislocation Required Intervention 39 Female 165 lb 10/23/2008 Physician Canada
Primary
Concomitant
Rhabdomyolysis Other Serious 4/17/2008 Male 134 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/17/2008 Male 134 lb 11/20/2008 Japan
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 45 Female 141 lb 12/2/2008 Consumer Canada
Primary
Concomitant
Post Procedural Complication Other Serious 11/18/2008 77 Female 185 lb 11/26/2008 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonic Epilepsy Other Serious 10/10/2008 69 Female 137 lb 11/26/2008 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening Male 11/26/2008 Physician Canada
Primary
Secondary
Concomitant
Bronchospasm Other Serious 1 Female 20 lb 12/16/2008
Primary
Secondary
Concomitant
Wernicke-korsakoff Syndrome Hospitalization 11/13/2008 69 Male 160 lb 12/13/2008 Pharmacist United States
Primary
Concomitant
Arteriospasm Coronary Other Serious 72 Female 126 lb 12/31/2008 Japan
Primary
Concomitant
Arteriospasm Coronary Life Threatening 6/7/2006 72 Female 126 lb 1/22/2009 Other Health Professional Japan
Primary
Concomitant
Arteriospasm Coronary Life Threatening 6/7/2006 72 Female 126 lb 1/30/2009 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 70 Male 3/2/2009 Taiwan, Province Of China
Primary
Concomitant
Ventricular Tachycardia Other Serious 35 Female 5/18/2009
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 6/15/2009 United Kingdom
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/1/2009 United Kingdom
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Required Intervention 52 Male 86 lb 6/25/2009 Other Health Professional Japan
Primary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/13/2009 United Kingdom
Primary
Secondary
Concomitant
Sinus Arrhythmia Other Serious 46 Male 176 lb 7/30/2009
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 6/27/2008 8 Male 35 lb 8/25/2009 Pharmacist United States
Primary
Concomitant
Status Epilepticus Other Serious 3/25/2009 Female 106 lb 11/5/2009 Japan
Primary
Concomitant
Epilepsy Other Serious 3/25/2009 Female 106 lb 12/3/2009 Japan
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 3/25/2009 Female 106 lb 12/8/2009 Japan
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 12/10/2009 United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 35 Female 115 lb 1/21/2010
Primary
Secondary
Concomitant
Tachycardia Other Serious 35 Female 115 lb 1/21/2010
Primary
Secondary
Concomitant
Somnolence Other Serious 37 Female 1/15/2010 United States
Primary
Concomitant
Tachycardia Hospitalization 1/25/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Death 12/24/2009 Female 110 lb 1/29/2010 Physician Japan
Primary
Concomitant
Parkinsonism Other Serious 35 Female 115 lb 2/2/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Hyperthermia Malignant Other Serious 53 Female 128 lb 2/16/2010 Physician Japan
Primary
Secondary
Concomitant
Parkinsonism Other Serious 35 Female 115 lb 2/22/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Obstructive Airways Disorder Other Serious 12/8/2009 Male 137 lb 2/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 2/25/2010 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 12/24/2009 Female 110 lb 2/25/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 1/1/2010 30 Male 205 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 35 Female 3/26/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 35 4/1/2010
Primary
Secondary
Concomitant
Tachycardia Other Serious 4/27/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Cholangitis Other Serious 5/9/2003 5/13/2010 Physician Finland
Primary
Secondary
Concomitant
Cholangitis Hospitalization 5/9/2003 5/24/2010 Physician Finland
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 53 Male 6/4/2010 Other Health Professional United States
Primary
Secondary
Post Procedural Haematoma Life Threatening 8/18/2009 63 Male 243 lb 6/15/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/1/2007 68 Male 159 lb 6/17/2010 Lawyer United States
Primary
Concomitant
Pulmonary Mass Other Serious 48 Male 159 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 77 lb 8/13/2010 Consumer Canada
Primary
Concomitant
Pyrexia Other Serious 55 Male 172 lb 8/27/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 55 Male 172 lb 9/2/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11 Female 77 lb 9/9/2010
Primary
Secondary
Pyrexia Other Serious 55 Male 172 lb 9/10/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 68 Female 84 lb 9/8/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 68 Female 84 lb 9/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 7/1/2009 41 Female 9/22/2010 Other Health Professional Switzerland
Primary
Secondary
Acute Generalised Exanthematous Pustulosis Other Serious 4 Male 9/29/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/4/2010 74 Male 11/1/2010 Pharmacist United States
Primary
Concomitant
Electromechanical Dissociation Other Serious 21 Male 126 lb 11/5/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Pulse Absent Other Serious 21 Male 126 lb 11/5/2010 Physician United States
Primary
Secondary
Concomitant
Prinzmetal Angina Life Threatening 50 Male 139 lb 2/14/2011 Physician Japan
Primary
Concomitant
Renal Impairment Death 1/22/2004 64 Male 172 lb 3/10/2011 Consumer United States
Primary
Concomitant
Fear Hospitalization 1/22/2004 64 Male 172 lb 3/10/2011 Lawyer United States
Primary
Concomitant
No Adverse Event Other Serious 2/12/2010 33 Female 3/17/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 72 Male 161 lb 3/21/2011 Other Health Professional Japan
Primary
Concomitant
Pain Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 5/13/2004 67 Male 238 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Polyuria Other Serious 18 Male 180 lb 3/22/2011 Other Health Professional United States
Primary
Concomitant
Heart Rate Decreased Other Serious 72 Male 161 lb 3/25/2011 Other Health Professional Japan
Primary
Concomitant
Caesarean Section Hospitalization 42 Female 3/16/2011 Other Health Professional United States
Primary
Secondary
Hypoglycaemia Other Serious 2 Male 11 lb 3/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Caesarean Section Other Serious Male 3/16/2011 Other Health Professional United States
Primary
Secondary
Nephrogenic Diabetes Insipidus Other Serious 18 Male 179 lb 3/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Heart Rate Decreased 10/10/2010 72 Male 161 lb 4/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 74 Female 152 lb 4/15/2011 Lawyer United States
Primary
Concomitant
Hypotension 10/10/2010 72 Male 161 lb 4/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypotension 12/10/2010 72 Male 161 lb 4/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Nervousness Disability 57 Female 170 lb 5/2/2011 Lawyer United States
Primary
Concomitant
Pain Hospitalization 6/29/2003 59 Male 221 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Death 3/23/2005 69 Male 223 lb 5/26/2011 Consumer United States
Primary
Concomitant
Accidental Exposure Hospitalization 64 Female 154 lb 5/20/2011 Other Health Professional Italy
Primary
Concomitant
Injury Hospitalization 10/2/2004 64 Female 125 lb 6/8/2011 Physician United States
Primary
Concomitant
Renal Failure Other Serious 12/22/2004 73 Female 139 lb 6/8/2011 Lawyer United States
Primary
Concomitant
Fear Other Serious 4/29/2005 78 Male 210 lb 6/8/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 74 Female 168 lb 7/5/2011 Lawyer United States
Primary
Concomitant
Nervousness Death 57 Female 170 lb 7/6/2011 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 7/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tongue Paralysis Other Serious 7/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Hospitalization 9/6/2007 70 Male 190 lb 7/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Injury Other Serious 9/6/2007 70 Male 190 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Intracranial Venous Sinus Thrombosis Other Serious 9/1/2005 24 Female 140 lb 8/12/2011 Lawyer United States
Primary
Concomitant
Atelectasis Hospitalization 77 Male 132 lb 8/12/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Hypotension Hospitalization 11/9/2006 54 Male 108 lb 10/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypotension Hospitalization 11/9/2006 54 Male 108 lb 10/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypertension Hospitalization 20 Male 11/8/2011 Physician United States
Primary
Secondary

Drug Data