Levothyroxine combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 6/22/2008 78 Female 129 lb 12/15/2008 Physician United States
Primary
Concomitant
Thermal Burn Other Serious 1/1/2008 Male 280 lb 12/22/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 7/25/2006 30 Female 174 lb 12/16/2008 United States
Primary
Secondary
Concomitant
Pneumonia Death 8/1/2008 Female 201 lb 12/24/2008 Physician United States
Primary
Concomitant
Drug Interaction Hospitalization 9/29/2008 64 Female 12/30/2008 Other Health Professional France
Primary
Concomitant
Interacting
Cerebrovascular Accident Hospitalization 12/26/2006 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Cerebrovascular Accident Hospitalization 12/26/2006 72 Female 1/22/2009 Consumer United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 1/7/2009 72 Female 1/23/2009 Other Health Professional Germany
Primary
Secondary
Cerebrovascular Accident Hospitalization 12/26/2006 72 Female 1/23/2009 Consumer Germany
Primary
Secondary
Dyspnoea Hospitalization 1/7/2009 72 Female 1/31/2009 Other Health Professional Germany
Primary
Secondary
Thermal Burn Other Serious 1/1/2008 Male 280 lb 2/2/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Death 1/8/2009 58 Female 2/5/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased 1/31/2009 Male 2/6/2009 Consumer
Primary
Concomitant
Pancytopenia Hospitalization 5/14/2009 54 Female 264 lb 5/26/2009 Pharmacist United States
Primary
Concomitant
Pain Death 68 Male 5/26/2009 United States
Primary
Concomitant
Phlebitis Other Serious 1/1/2009 73 Male 6/3/2009 Other Health Professional Canada
Primary
Secondary
Drug Interaction Other Serious Female 8/10/2009 Physician United States
Primary
Concomitant
Interacting
White Blood Cell Count Increased Hospitalization 6/24/2009 78 Female 126 lb 8/8/2009 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 72 Female 8/12/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 46 Male 8/13/2009 United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2009 80 Female 105 lb 8/20/2009 United States
Primary
Concomitant
Feeling Hot 5/13/2009 Female 240 lb 8/29/2009 United States
Primary
Concomitant
Pain In Extremity Female 8/29/2009 United States
Primary
Concomitant
Respiratory Disorder Death 68 Male 9/18/2009 United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2009 Female 9/29/2009 Other Health Professional United States
Primary
Concomitant
Swelling Face Other Serious 1/1/2009 Female 261 lb 11/5/2009 Consumer United States
Primary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/6/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/18/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2009 Female 261 lb 12/11/2009 Consumer United States
Primary
Concomitant
Surgery Other Serious 2/1/2010 Female 90 lb 3/12/2010 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/15/2010 Male 267 lb 3/26/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Hip Surgery Other Serious 1/1/2008 87 Female 90 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 5/19/2009 78 Female 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred 4/27/2009 69 Male 204 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 5/19/2009 78 Female 6/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Nausea 3/1/2007 Female 7/12/2010 Consumer United States
Primary
Concomitant
Interacting
Vomiting Hospitalization 8/6/2006 68 Female 173 lb 7/9/2010 United States
Primary
Concomitant
Swelling Death 54 Female 172 lb 7/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/2/2007 78 Male 7/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 3/1/2008 44 Female 7/30/2010 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2008 87 Female 8/3/2010 United States
Primary
Concomitant
Vomiting Other Serious 10/4/2007 63 Female 218 lb 8/4/2010 Lawyer United States
Primary
Concomitant
Vessel Puncture Site Haematoma Other Serious 3/1/2008 45 Female 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/11/2010 63 Female 184 lb 8/13/2010 Physician United States
Primary
Concomitant
Psychomotor Hyperactivity Other Serious 1/1/2010 80 Female 140 lb 8/20/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/11/2010 63 Female 184 lb 8/24/2010 Physician United States
Primary
Concomitant
Pain Hospitalization Female 8/23/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Life Threatening 8/12/2010 87 Male 178 lb 9/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 1/1/2010 91 Female 105 lb 9/14/2010 Consumer United States
Primary
Concomitant
Paranoia Other Serious 80 Female 9/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/12/2010 87 Male 179 lb 9/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 7/15/2010 76 Female 110 lb 9/28/2010 Ireland
Primary
Concomitant
Renal Failure Acute Life Threatening 8/12/2010 87 Male 179 lb 10/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/1/2010 79 Female 165 lb 10/19/2010 Pharmacist United States
Primary
Concomitant
Knee Arthroplasty Hospitalization Female 10/28/2010 Consumer United States
Primary
Concomitant
Cardiac Valve Disease Hospitalization 90 Male 11/1/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/8/2005 65 Male 258 lb 11/2/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/16/2008 82 Female 174 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 11/19/2007 71 Male 11/2/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Somnolence 7/16/2010 79 Male 150 lb 9/7/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 8/20/2010 87 Female 88 lb 11/8/2010 Pharmacist United States
Primary
Concomitant
Sepsis Death 11/11/2010 Physician United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 79 Male 11/2/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 4/1/2009 76 Male 11/17/2010 Physician United States
Primary
Concomitant
Weight Decreased 69 Male 149 lb 11/9/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 11/18/2010 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 2/1/2010 65 Male 172 lb 11/24/2010 Consumer United States
Primary
Concomitant
Headache 10/1/2010 81 Female 125 lb 12/6/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 82 Female 11/17/2010 United States
Primary
Concomitant
Heart Rate Irregular Other Serious 1/1/2009 73 Female 133 lb 12/15/2010 Consumer United States
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 11/1/2010 76 Male 12/30/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 11/24/2010 80 Female 153 lb 12/20/2010 Physician United States
Primary
Concomitant
Product Quality Issue 72 Female 1/7/2011 Consumer United States
Primary
Concomitant
Meniscus Lesion Other Serious 12/1/2009 80 Female 225 lb 1/10/2011 Physician United States
Primary
Concomitant
Diverticulitis Death 9/14/2010 76 Male 1/12/2011 Physician United States
Primary
Concomitant
Muscle Spasms Other Serious 64 Female 1/14/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tendonitis Other Serious 5/2/2000 43 Female 270 lb 1/17/2011 Consumer United States
Primary
Concomitant
Asthenia Other Serious 12/9/2010 78 Female 172 lb 1/17/2011 Consumer United States
Primary
Concomitant
Gait Disturbance Other Serious 12/1/2010 79 Female 240 lb 1/17/2011 Consumer United States
Primary
Secondary
Concomitant
Vomiting 12/4/2010 Female 1/18/2011 Consumer
Primary
Concomitant
Insomnia Other Serious 1/1/2010 80 Female 140 lb 1/18/2011 Consumer United States
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 11/13/2009 63 Female 148 lb 1/7/2011 Physician Canada
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 78 Female 1/5/2011 United States
Primary
Concomitant
Cellulitis Hospitalization 4/15/2007 76 Female 143 lb 2/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Contusion Hospitalization 9/18/2010 87 Female 112 lb 2/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Female 121 lb 2/23/2011 Consumer United States
Primary
Concomitant
Dyslipidaemia Hospitalization 46 Male 326 lb 2/9/2011 Lawyer United States
Primary
Concomitant
Dyspepsia Hospitalization 1/17/2011 88 Female 150 lb 1/26/2011 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/20/2011 81 Male 190 lb 2/3/2011 Pharmacist United States
Primary
Concomitant
Gait Disturbance Other Serious 12/1/2010 79 Female 240 lb 3/1/2011 Consumer United States
Primary
Secondary
Concomitant
Diverticulitis Death 9/14/2010 76 Male 195 lb 3/2/2011 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 9/18/2010 87 Female 112 lb 3/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Overdose Other Serious 9/18/2010 87 Female 112 lb 3/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Other Serious 8/26/2009 46 Female 170 lb 3/14/2011 Pharmacist United States
Primary
Secondary
Concomitant
Nausea Hospitalization 7/12/1999 63 Female 3/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 11/1/2010 80 Female 193 lb 3/16/2011 Consumer United States
Primary
Concomitant
Haemorrhage Other Serious 12/1/2007 84 Male 176 lb 3/17/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 4/25/2008 40 Female 194 lb 3/23/2011 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/13/2011 66 Female 268 lb 3/17/2011 Pharmacist United States
Primary
Secondary
Concomitant
Fall Hospitalization 6/1/2010 53 Male 3/11/2011 Consumer United States
Primary
Concomitant
Periodontal Disease Other Serious 2/8/2005 65 Male 258 lb 4/13/2011 Physician United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 11/1/2008 72 Male 184 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Dizziness 7/1/2010 78 Female 130 lb 8/17/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 1/1/2008 51 Male 8/23/2011 Lawyer United States
Primary
Concomitant
Peroneal Nerve Palsy Other Serious 1/1/2010 81 Female 165 lb 9/1/2011 Consumer United States
Primary
Concomitant
Drug Ineffective For Unapproved Indication Other Serious Female 165 lb 9/7/2011 Consumer United States
Primary
Secondary
Concomitant
Lung Disorder Other Serious 1/1/2011 65 Female 150 lb 9/21/2011 Consumer United States
Primary
Concomitant
Epistaxis Other Serious 3/24/2011 47 Female 137 lb 10/25/2011 Pharmacist United Kingdom
Primary
Concomitant
Somnolence Female 11/2/2011 Consumer United States
Primary
Secondary
Concomitant
Lung Disorder Other Serious 1/1/2011 65 Female 150 lb 11/2/2011 Consumer United States
Primary
Concomitant
Seasonal Affective Disorder Other Serious 1/1/2010 66 Female 225 lb 11/4/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 1/1/2011 82 Female 135 lb 1/18/2012 Consumer United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 80 Male 2/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 80 Male 2/14/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 80 Male 2/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 80 Male 2/21/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Pressure Fluctuation 2/1/2012 77 Male 160 lb 2/28/2012 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2/4/2012 73 Female 216 lb 2/28/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 80 Male 2/28/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 80 Male 2/29/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 80 Male 3/5/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 12/1/2011 71 Male 331 lb 3/8/2012 Consumer United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 80 Male 3/12/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 80 Male 3/20/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abnormal Dreams 1/1/2011 66 Male 290 lb 3/21/2012 Consumer United States
Primary
Concomitant
Hallucination 3/1/2012 76 Female 160 lb 3/23/2012 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 80 Male 3/23/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arthritis Other Serious 3/1/2012 74 Female 185 lb 3/28/2012 Consumer United States
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2003 55 Female 249 lb 4/23/2012 Consumer United States
Primary
Concomitant
Pain 4/1/2012 64 Female 249 lb 4/24/2012 Consumer United States
Primary
Secondary
Concomitant
Rash Maculo-papular 2/27/2012 42 Female 4/30/2012 Physician United States
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2003 55 Female 249 lb 5/9/2012 Physician United States
Primary
Concomitant
Incorrect Dose Administered 4/1/2012 64 Female 249 lb 5/11/2012 Physician United States
Primary
Secondary
Concomitant
Poor Peripheral Circulation Hospitalization 4/1/2012 85 Female 175 lb 5/23/2012 Consumer United States
Primary
Concomitant
Drug Level Changed Other Serious 5/30/2012 60 Female 240 lb 6/8/2012 Consumer United States
Primary
Concomitant
Fall Hospitalization 5/1/2012 86 Female 145 lb 7/9/2012 Consumer United States
Primary
Secondary
Concomitant
Erythema Female 180 lb 7/12/2012 Consumer United States
Primary
Concomitant
Insomnia 7/14/2012 71 Female 201 lb 7/22/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2012 73 Female 170 lb 7/25/2012 Consumer United States
Primary
Concomitant
Drug Ineffective 7/30/2012 83 Male 145 lb 8/15/2012 Consumer United States
Primary
Concomitant
Tooth Abscess Other Serious 7/1/2012 75 Female 139 lb 8/20/2012 Consumer United States
Primary
Concomitant
Rash Erythematous Other Serious 6/8/2012 79 Male 147 lb 8/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Skin Lesion 10/26/2007 62 Female 157 lb 12/19/2012 Other Health Professional Us
Primary
Concomitant
Pruritus Generalised Other Serious 10/25/2009 66 Female 150 lb 9/24/2012 Other Health Professional Us
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 2008 Female 134 lb 11/15/2012 Physician Country Not Specified
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 3/2011 Female 166 lb 9/28/2012 Physician Ca
Primary
Concomitant
Pyrexia Other Serious 10/2005 77 Female 160 lb 12/21/2012 Other Health Professional Us
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 10/2011 45 Female 9/6/2012 Physician Us
Primary
Concomitant

Drug Data