Levothyroxine combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Fluctuation 6/8/2007 43 Female 142 lb 8/14/2008 Pharmacist United States
Primary
Secondary
Concomitant
Labile Blood Pressure 3/1/2008 Male 182 lb 6/18/2008 Physician United States
Primary
Concomitant
International Normalised Ratio Hospitalization 78 Female 187 lb 8/28/2008 Other Health Professional Japan
Primary
Concomitant
Interacting
Occult Blood Positive Hospitalization 9/9/2008 64 Female 284 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 67 Male 3/5/2009 United Kingdom
Primary
Concomitant
Ovarian Neoplasm Other Serious 10/1/2008 Female 150 lb 3/16/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 12/1/2006 82 Male 3/17/2009 Lawyer United States
Primary
Concomitant
Sensory Loss Other Serious 5/23/2007 Male 251 lb 3/20/2009 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/3/2009 68 Female 5/15/2009 Pharmacist United States
Primary
Concomitant
Rash Other Serious 3/3/2005 Female 5/29/2009 Other Health Professional United States
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 5/5/2009 77 Male 172 lb 6/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling 1/1/2009 Female 160 lb 6/11/2009 Other Health Professional
Primary
Concomitant
Rash Other Serious 3/3/2005 Female 6/12/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Vomiting Hospitalization 10/13/2006 65 Female 167 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 72 Female 8/13/2009 Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2009 Female 8/18/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Other Serious 7/29/2009 79 Male 8/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome 9/1/2008 Female 8/19/2009 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 64 Female 8/20/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2007 74 Female 134 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Venous Insufficiency Other Serious 2/27/2008 45 Male 328 lb 9/4/2009 Physician United States
Primary
Concomitant
Venous Insufficiency Other Serious 45 Male 328 lb 9/4/2009 Physician United States
Primary
Concomitant
Death Death Female 140 lb 9/9/2009 Consumer United States
Primary
Concomitant
Social Avoidant Behaviour Other Serious 69 Female 138 lb 9/25/2009 Pharmacist United States
Primary
Secondary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Pathological Fracture Hospitalization 72 Male 9/23/2009 United States
Primary
Concomitant
Cardiac Failure Death 5/1/2009 Female 140 lb 10/12/2009 Physician United States
Primary
Concomitant
Sepsis Hospitalization Male 10/13/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 11/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 87 Female 11/4/2009 United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 4/20/2006 61 Female 121 lb 11/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Increased Upper Airway Secretion Other Serious 1/1/2009 Female 140 lb 12/9/2009 Consumer United States
Primary
Concomitant
Urinary Retention Other Serious Female 140 lb 1/5/2010 Consumer United States
Primary
Secondary
Concomitant
Increased Upper Airway Secretion Other Serious 1/1/2009 Female 140 lb 1/15/2010 Physician United States
Primary
Concomitant
Drug Resistance Other Serious 40 Female 207 lb 2/9/2010 Portugal
Primary
Concomitant
Cerebrovascular Accident Other Serious Female 2/26/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection 83 Female 132 lb 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Somnolence Required Intervention 2/26/2009 68 Male 180 lb 3/17/2009 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization 11/13/2009 82 Female 12/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/9/2010 70 Female 3/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2007 74 Female 134 lb 3/3/2010 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious Male 3/4/2010 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization Female 3/5/2010 Other Health Professional United States
Primary
Concomitant
Tooth Infection Other Serious 1/1/1992 Female 3/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Insufficiency 2/27/2008 45 Male 328 lb 10/5/2009 Physician United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 9/1/1999 Female 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious Male 3/10/2010 United States
Primary
Secondary
Concomitant
Tremor Other Serious Male 3/11/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 10/8/2009 66 Female 3/31/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 244 lb 4/9/2010 Physician United States
Primary
Concomitant
Potentiating Drug Interaction Hospitalization 69 Female 4/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Death 66 Male 4/6/2010 United States
Primary
Concomitant
Melaena Required Intervention 12/7/2009 57 Male 168 lb 12/11/2009 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 4/13/2010 68 Male 240 lb 4/20/2010 Consumer United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 69 Female 4/15/2010 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious Female 160 lb 4/21/2010 Other Health Professional United States
Primary
Concomitant
Myositis Hospitalization 12/13/2009 78 Female 171 lb 4/21/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization Female 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/1/2010 66 Female 4/22/2010 Physician United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 3/4/1996 25 Female 4/26/2010 United States
Primary
Secondary
Concomitant
Synovial Cyst Hospitalization 2/3/2010 68 Female 4/26/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2010 88 Male 4/19/2010 Consumer United States
Primary
Concomitant
Synovial Cyst Hospitalization 2/1/2010 68 Female 4/28/2010 Consumer United States
Primary
Secondary
Concomitant
Trigger Finger Other Serious 12/1/2009 80 Female 225 lb 4/30/2010 United States
Primary
Concomitant
Loss Of Consciousness Other Serious Female 160 lb 5/4/2010 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 4/5/2010 89 Male 5/5/2010 Consumer United States
Primary
Concomitant
Unevaluable Event 9/18/2007 80 Female 162 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Cellulitis Hospitalization 7/11/2010 76 Male 217 lb 7/19/2010 United States
Primary
Concomitant
Respiratory Failure Death Female 108 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 4/5/2008 81 Male 163 lb 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Feeling Abnormal 2/18/2009 70 Female 8/3/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Cough 1/1/2006 74 Female 272 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious 4/21/2008 56 Female 8/11/2010 Lawyer United States
Primary
Concomitant
Hypokalaemia Hospitalization 6/29/2010 65 Male 8/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/15/2006 62 Female 123 lb 8/12/2010 United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 6/4/2010 57 Male 290 lb 8/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hyposmia 6/1/2009 74 8/27/2010 Consumer United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 80 Female 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Spasms 5/1/2009 75 Female 150 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation Male 215 lb 8/28/2010 United States
Primary
Concomitant
Dizziness 2/12/2010 64 Female 157 lb 8/28/2010 United States
Primary
Concomitant
Hypokalaemia Other Serious 6/29/2010 65 Male 9/1/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 8/30/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 9/1/2010 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/1/2010 55 Female 9/1/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/16/2007 78 Female 130 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 6/29/2010 65 Male 9/6/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/23/2010 89 Female 9/2/2010 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 6/14/2010 53 Female 250 lb 8/27/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 326 lb 9/1/2010 United States
Primary
Concomitant
Drug Ineffective Other Serious 80 Female 9/13/2010
Primary
Secondary
Vertigo Other Serious 9/3/2010 70 Male 190 lb 9/15/2010 Physician Sweden
Primary
Secondary
Concomitant
Drug Effect Decreased 1/1/2009 69 Female 190 lb 9/15/2010 Physician United States
Primary
Concomitant
Vaginitis Bacterial Other Serious 3/4/1996 25 Female 9/28/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/6/2006 68 Female 173 lb 9/21/2010 United States
Primary
Concomitant
Rash Maculo-papular Other Serious 9/2/2010 62 Female 356 lb 9/3/2010 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 1/3/2008 48 Male 258 lb 10/6/2010 Lawyer United States
Primary
Concomitant
Catheterisation Cardiac Hospitalization Female 235 lb 10/6/2010 Physician United States
Primary
Concomitant
Urticaria Other Serious 1/1/2010 77 Male 213 lb 10/7/2010 Physician United States
Primary
Concomitant
Troponin Increased Other Serious Female 175 lb 10/7/2010 Physician Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 3/16/2008 82 Female 174 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 4/21/2008 56 Female 10/11/2010 Lawyer United States
Primary
Concomitant
Thrombosis Hospitalization 1/1/2010 43 Male 258 lb 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dry Eye 67 Female 250 lb 10/13/2010 Consumer United States
Primary
Concomitant
Vessel Puncture Site Haematoma Other Serious 3/1/2008 45 Female 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Limb Fracture Required Intervention 1/1/2010 69 Male 170 lb 10/7/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor 1/25/2010 67 Male 180 lb 10/22/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/8/2005 65 Male 258 lb 10/26/2010 Physician United States
Primary
Secondary
Concomitant
Delirium Other Serious 80 Female 10/28/2010 Other Health Professional United States
Primary
Concomitant
Swollen Tongue 84 Male 10/13/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/24/2010 77 Male 11/4/2010 Physician United States
Primary
Concomitant
Diverticulitis Hospitalization 1/3/2009 84 Male 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Death 11/4/2006 78 Female 164 lb 11/5/2010 Physician United States
Primary
Concomitant
Psychiatric Decompensation Other Serious 10/22/2010 29 11/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 5/17/2010 76 Female 11/15/2010 Consumer France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/28/2010 77 Male 244 lb 11/19/2010 Pharmacist United States
Primary
Secondary
Concomitant
Prostatic Operation Other Serious 9/20/2010 75 Male 230 lb 12/14/2010 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 85 Female 165 lb 12/17/2010 Pharmacist Canada
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 9/15/2010 60 Female 1/10/2011 Physician United States
Primary
Secondary
Concomitant
Psychiatric Decompensation Other Serious 10/22/2010 29 Female 1/11/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 46 Male 1/11/2011 Consumer United States
Primary
Concomitant
Musculoskeletal Discomfort 12/12/2010 70 Female 265 lb 1/18/2011 Consumer
Primary
Secondary
Concomitant
Radiculitis Lumbosacral Hospitalization 3/4/1996 25 Female 1/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Gangrene Other Serious 1/1/2009 74 Female 240 lb 1/13/2011 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 1/1/2008 56 Female 2/3/2011 Lawyer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death 73 Female 96 lb 2/18/2011 Consumer United States
Primary
Concomitant
Hot Flush 9/27/2010 71 Male 285 lb 1/24/2011 United States
Primary
Concomitant
Mobility Decreased Other Serious 9/1/2006 50 Male 175 lb 3/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/1/2006 50 Male 175 lb 3/15/2011 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 9/18/2010 87 Female 112 lb 3/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 9/1/2006 50 Male 175 lb 4/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/4/2001 64 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 3/1/2011 55 Female 246 lb 4/6/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/11/2008 51 Female 4/8/2011 Lawyer United States
Primary
Secondary
Concomitant
Palpitations 1/1/2010 73 Female 183 lb 5/6/2011 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 2/1/2011 58 Female 196 lb 5/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Disorder Other Serious 1/1/2010 73 Female 183 lb 5/26/2011 Consumer United States
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 5/18/2011 57 Female 7/13/2011 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/6/2011 74 Female 7/14/2011 Physician United Kingdom
Primary
Concomitant
Tooth Infection Other Serious 4/1/2011 81 Female 165 lb 7/14/2011 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2011 73 Male 9/28/2011 Physician United States
Primary
Concomitant
Flatulence Hospitalization 1/1/2000 84 Male 10/3/2011 Physician United States
Primary
Secondary
Concomitant
Blood Test Abnormal 11/13/2011 59 Female 195 lb 11/19/2011 Consumer United States
Primary
Concomitant
Rectal Cancer Hospitalization 1/13/2010 52 Female 357 lb 3/31/2012 Other Health Professional Sweden
Primary
Concomitant

Drug Data