Levothyroxine combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Fluctuation 6/8/2007 43 Female 142 lb 8/14/2008 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/26/1999 Female 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Waist Circumference Increased Other Serious 6/3/2006 Male 8/26/2008 Lawyer United States
Primary
Concomitant
Vision Blurred 7/1/2007 81 Female 8/26/2008 Consumer United States
Primary
Concomitant
Thermal Burn Other Serious 1/1/2008 Male 280 lb 12/22/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Death 8/1/2008 Female 201 lb 12/24/2008 Physician United States
Primary
Concomitant
Convulsion Other Serious 7/31/2008 Female 243 lb 12/29/2008 Physician Chile
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 10/16/2008 Male 227 lb 12/29/2008 Other Health Professional United States
Primary
Concomitant
Drug Interaction Hospitalization 9/29/2008 64 Female 12/30/2008 Other Health Professional France
Primary
Concomitant
Interacting
Cardio-respiratory Arrest Death Male 225 lb 1/6/2009 Physician United States
Primary
Concomitant
Thermal Burn Other Serious 1/1/2008 Male 280 lb 2/2/2009 Other Health Professional United States
Primary
Concomitant
Discomfort 68 Female 2/4/2009 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/1/2007 Female 2/4/2009 Consumer
Primary
Concomitant
Scab Hospitalization 66 Male 2/28/2009 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/13/2009 Female 356 lb 3/9/2009 Other Health Professional United States
Primary
Concomitant
Troponin Increased Hospitalization 1/29/2009 74 Male 3/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sensory Loss Other Serious 5/23/2007 Male 251 lb 3/20/2009 Physician United States
Primary
Concomitant
Speech Disorder Other Serious 39 Female 220 lb 3/24/2009 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 2/13/2009 Female 161 lb 4/7/2009 United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/20/2009 Female 4/24/2009 Consumer
Primary
Concomitant
Respiratory Failure Life Threatening 2/13/2009 Female 161 lb 4/29/2009 United States
Primary
Concomitant
Respiratory Failure Life Threatening 2/13/2009 Female 161 lb 5/8/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/13/2009 Female 161 lb 5/20/2009 United States
Primary
Concomitant
Respiratory Failure Life Threatening 2/13/2009 Female 161 lb 6/1/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/28/2008 65 Male 5/24/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 65 Male 6/5/2009 United States
Primary
Concomitant
Headache Hospitalization 2/25/2009 58 Male 6/15/2009 Physician Italy
Primary
Concomitant
Vomiting Other Serious 1/1/2005 38 Female 252 lb 6/25/2009 United States
Primary
Concomitant
Pelvic Mass Hospitalization 4/17/2009 75 7/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pelvic Mass Hospitalization 4/17/2009 75 7/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 7/25/2009 Male 191 lb 8/7/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 65 Male 8/6/2009 United States
Primary
Concomitant
Vomiting Hospitalization 10/13/2006 65 Female 167 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 46 Male 8/13/2009 United States
Primary
Concomitant
Pelvic Mass Hospitalization 4/17/2009 75 8/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization Female 161 lb 8/19/2009 Physician United States
Primary
Concomitant
Nausea Hospitalization 64 Female 8/20/2009 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious Female 8/28/2009 Consumer United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Surgery Hospitalization 72 Female 9/25/2009 United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization Female 10/9/2009 Consumer United States
Primary
Concomitant
Infection Other Serious 6/27/2009 66 Male 10/13/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 38 Female 260 lb 10/14/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 72 Female 11/4/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 11/3/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 66 Male 2/5/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection 83 Female 132 lb 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea 10/1/2009 48 Female 1/28/2010 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Death Death 2/23/2010 Female 120 lb 3/8/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Female 280 lb 3/9/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 11/9/2009 Male 142 lb 3/15/2010 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 12/26/2009 66 Male 141 lb 3/15/2010 Physician Germany
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 10/8/2009 66 Female 3/31/2010 United States
Primary
Concomitant
Lethargy Hospitalization 3/31/2010 60 Female 4/16/2010 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 70 Female 270 lb 4/15/2010 Other Health Professional United States
Primary
Concomitant
Throat Irritation Hospitalization Female 4/21/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization Female 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Toe Amputation Hospitalization 65 Male 4/22/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/15/2010 4/23/2010 Pharmacist United Kingdom
Primary
Concomitant
Throat Irritation Hospitalization Female 4/29/2010 United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 3/31/2010 60 Female 4/29/2010 Physician United Kingdom
Primary
Concomitant
Pollakiuria 80 Female 155 lb 5/3/2010 United States
Primary
Concomitant
Transplant Rejection Hospitalization Female 5/4/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 12/26/2009 66 Male 141 lb 6/16/2010 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/19/2009 78 Female 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 5/19/2009 78 Female 6/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 85 Female 7/27/2010 Physician United States
Primary
Concomitant
Rib Fracture Other Serious Female 7/23/2010 Consumer United States
Primary
Concomitant
Alopecia 2/1/2010 79 Female 7/27/2010 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Death Female 108 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 65 Female 183 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 7/1/2010 80 Female 8/3/2010 Consumer Colombia
Primary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 7/1/2007 Female 230 lb 8/5/2010 United States
Primary
Concomitant
Respiratory Arrest Hospitalization 85 Female 8/6/2010 Physician United States
Primary
Concomitant
Scratch Hospitalization 6/28/2010 58 Male 175 lb 8/5/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 6/11/2010 85 Female 8/11/2010 Physician United States
Primary
Concomitant
Disease Progression Hospitalization 7/1/2010 62 223 lb 8/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Weight Increased Hospitalization 12/3/2009 61 Male 221 lb 8/13/2010 Other Health Professional United States
Primary
Concomitant
Pancreatitis Other Serious 6/1/2010 60 Female 322 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/14/2010 50 Male 8/18/2010 Physician Germany
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 6/4/2010 57 Male 290 lb 8/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/14/2010 63 Male 8/25/2010 Consumer
Primary
Concomitant
Rash 7/3/2010 52 Female 250 lb 8/29/2010 Consumer United States
Primary
Concomitant
Acute Leukaemia Other Serious 3/26/2010 Female 8/31/2010 Other Health Professional Belgium
Primary
Concomitant
Dyspnoea Hospitalization 8/14/2010 63 Male 9/3/2010 Consumer
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 6/14/2010 53 Female 250 lb 8/27/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 326 lb 9/1/2010 United States
Primary
Concomitant
Pancreatitis Other Serious 5/8/2008 71 Female 359 lb 9/14/2010 Other Health Professional United States
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2010 91 Female 105 lb 9/14/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Female 280 lb 9/16/2010 Consumer United States
Primary
Concomitant
Tremor Hospitalization 7/11/2010 80 Female 9/16/2010 Consumer Colombia
Primary
Concomitant
Respiratory Tract Infection Hospitalization 7/15/2010 76 Female 110 lb 9/28/2010 Ireland
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/5/2010 57 Male 175 lb 10/6/2010 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 7/15/2010 63 Female 192 lb 10/19/2010 Consumer United States
Primary
Secondary
Concomitant
Death Death Female 145 lb 10/19/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Polymyositis Hospitalization 1/1/2009 70 Female 10/29/2010 Consumer United States
Primary
Concomitant
Cardiac Valve Disease Hospitalization 90 Male 11/1/2010 Consumer United States
Primary
Secondary
Concomitant
Vein Disorder Other Serious 41 Female 11/1/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Syncope Other Serious 68 Female 137 lb 11/4/2010 Consumer United States
Primary
Concomitant
Paraesthesia 4/28/2008 50 Female 11/11/2010 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/15/2010 67 Female 215 lb 12/1/2010 United States
Primary
Concomitant
Uterine Cancer Hospitalization Female 12/2/2010 Physician Netherlands
Primary
Concomitant
Urticaria Hospitalization 6/24/2010 44 Female 12/1/2010 Pharmacist United States
Primary
Concomitant
Paraesthesia Other Serious 10/1/2010 72 Female 180 lb 11/23/2010 Consumer United States
Primary
Concomitant
Myalgia 73 Male 220 lb 12/14/2010 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 11/22/2005 41 Male 170 lb 12/29/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 280 lb 3/9/2010 Consumer United States
Primary
Concomitant
Vein Disorder Other Serious 11/17/2010 41 Female 246 lb 12/23/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 7/1/2010 50 Female 158 lb 12/30/2010 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 12/1/2009 56 Male 219 lb 1/4/2011 Consumer United States
Primary
Secondary
Concomitant
Myositis Other Serious 7/1/2010 50 Female 158 lb 1/7/2011 Other Health Professional United States
Primary
Concomitant
Product Quality Issue 72 Female 1/7/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 9/15/2010 60 Female 1/10/2011 Physician United States
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 46 Male 1/11/2011 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 8/12/2010 64 Female 207 lb 8/31/2010 Pharmacist United States
Primary
Concomitant
Dizziness 12/8/2010 80 Female 1/13/2011 Consumer
Primary
Concomitant
Muscle Spasms Other Serious 64 Female 1/14/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Sense Of Oppression Hospitalization 1/1/2010 -1 Female 12 lb 1/17/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 10/1/2010 72 Female 180 lb 1/14/2011 Consumer United States
Primary
Concomitant
Dyslipidaemia Hospitalization 46 Male 326 lb 2/9/2011 Lawyer United States
Primary
Concomitant
Activities Of Daily Living Impaired 12/8/2010 80 Female 2/27/2011 Consumer United States
Primary
Concomitant
Endometrial Hypertrophy Hospitalization 12/6/2010 80 Female 179 lb 1/17/2011 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/25/2011 68 Female 136 lb 3/9/2011 Physician United States
Primary
Concomitant
Respiratory Distress Hospitalization Male 104 lb 3/10/2011 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 1/25/2011 68 Female 136 lb 3/14/2011 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 1/1/2011 71 Female 3/16/2011 Consumer United States
Primary
Concomitant
Flatulence 2/3/2011 81 Female 3/16/2011 Consumer United States
Primary
Concomitant
Liver Disorder Hospitalization 5/1/2010 Female 3/15/2011 Physician Mexico
Primary
Concomitant
Wheezing Hospitalization 3/13/2011 Female 15 lb 4/4/2011 Other Health Professional United States
Primary
Concomitant
Dysarthria Other Serious 1/1/2009 62 Male 4/14/2011 Pharmacist Canada
Primary
Secondary
Concomitant
Death Death 12/5/2009 75 Female 131 lb 5/5/2011 Physician United States
Primary
Concomitant
Death Death 12/5/2009 75 Female 131 lb 5/27/2011 Physician United States
Primary
Concomitant
Fibrosis Other Serious Female 163 lb 6/28/2011 Lawyer United States
Primary
Concomitant
Emotional Distress Death 2/1/2001 59 Female 143 lb 7/14/2011 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 7/25/2005 29 Female 255 lb 7/15/2011 Other Health Professional United States
Primary
Concomitant
Presyncope Other Serious 8/8/2011 57 Female 198 lb 8/9/2011 Consumer United States
Primary
Concomitant
Somnolence 9/1/2011 35 Female 185 lb 9/20/2011 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 8/3/2011 79 Female 9/29/2011 Colombia
Primary
Concomitant
Insomnia 8/12/2011 67 Male 10/3/2011 Consumer United States
Primary
Concomitant
Presyncope Other Serious 8/8/2011 57 Female 198 lb 10/21/2011 Consumer United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 2/9/2012 65 Female 295 lb 2/28/2012 Physician Netherlands
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 12/1/2011 71 Male 331 lb 3/8/2012 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious 10/1/2009 59 Female 351 lb 3/22/2012 Consumer United States
Primary
Secondary
Concomitant
Hypertension 11/1/2010 61 Female 214 lb 4/17/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data