Levothyroxine Sodium combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gerstmann's Syndrome Other Serious 3/9/2006 73 Female 3/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 3/17/2006 Female 175 lb 3/27/2006 Consumer Canada
Primary
Concomitant
Pancreatitis Life Threatening 3/1/2006 20 Female 3/23/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Gerstmann's Syndrome Other Serious 3/9/2006 73 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/26/2006 Male 168 lb 4/5/2006 Consumer Canada
Primary
Concomitant
Syncope Hospitalization 2/14/2006 88 Female 132 lb 4/5/2006 Other Health Professional France
Primary
Concomitant
Pancreatitis Life Threatening 3/1/2006 20 Female 3/31/2006 Germany
Primary
Secondary
Concomitant
Panic Disorder Hospitalization 1/1/2002 37 Female 214 lb 4/17/2006 Lawyer Canada
Primary
Concomitant
Gerstmann's Syndrome Other Serious 3/9/2006 73 Female 4/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/7/2005 79 Female 4/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hypertension Hospitalization 7/1/2002 44 Female 4/27/2006 Norway
Primary
Concomitant
Cerebral Infarction Hospitalization 3/19/2004 72 Female 4/28/2006 Norway
Primary
Concomitant
Hypertension Hospitalization 7/1/2002 44 Female 5/3/2006 Norway
Primary
Concomitant
Sensory Disturbance Disability Female 5/3/2006 Physician
Primary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Urticaria Generalised Other Serious 1/25/2006 71 Female 219 lb 6/5/2006 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 5/10/2006 Female 6/22/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 3/25/2006 80 Male 6/30/2006 France
Primary
Concomitant
Pulmonary Oedema Other Serious 9/4/2003 57 Female 8/21/2006 United States
Primary
Concomitant
Vomiting Other Serious 4/10/2006 Female 8/21/2006 Other Health Professional Denmark
Primary
Concomitant
Respiratory Rate Increased Other Serious 54 Female 8/29/2006 United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 9/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocythaemia Hospitalization 1/1/2006 79 Female 10/6/2006 Physician France
Primary
Concomitant
Sensory Disturbance Disability Female 10/10/2006 Physician
Primary
Concomitant
Thrombocythaemia Hospitalization 1/1/2006 79 Female 10/30/2006 Physician France
Primary
Concomitant
Vomiting Life Threatening 3/3/2006 20 Female 11/10/2006 Physician Germany
Primary
Concomitant
Synovitis Other Serious 9/4/2003 57 Female 11/17/2006 United States
Primary
Concomitant
Vomiting Life Threatening 3/1/2006 20 Female 11/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Humerus Fracture Hospitalization 11/14/2006 73 Female 11/27/2006 Physician France
Primary
Concomitant
Uterine Atrophy Hospitalization 1/1/2006 73 Female 12/13/2006 Physician Germany
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/11/2007 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 Physician United Kingdom
Primary
Concomitant
Mania Other Serious 12/29/2006 69 Female 1/29/2007 Physician United Kingdom
Primary
Concomitant
Unevaluable Event Other Serious 11/5/2006 Male 156 lb 2/12/2007 Physician France
Primary
Concomitant
Oral Pain Other Serious 11/21/2006 53 Female 2/16/2007 Physician United Kingdom
Primary
Concomitant
Nausea Other Serious 1/1/2003 Female 3/2/2007 Pharmacist United Kingdom
Primary
Concomitant
Nausea Other Serious 1/1/2003 Female 3/9/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/10/2006 80 Female 3/15/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 5/10/2006 80 Female 3/19/2007 Other Health Professional
Primary
Concomitant
Death Hospitalization 7/13/2006 Male 159 lb 5/9/2007 United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 7/13/2006 Male 159 lb 5/25/2007 United Kingdom
Primary
Concomitant
Fall Hospitalization 12/24/2006 Female 6/1/2007 Physician France
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 8/15/2005 23 Male 218 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 3/25/2006 Female 115 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/1/2005 23 Male 218 lb 6/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 36 Female 251 lb 7/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 2/25/2007 Female 117 lb 7/5/2007 Germany
Primary
Concomitant
Sudden Death Death 1/4/2006 36 Female 7/5/2007
Primary
Concomitant
Sudden Death Death 1/4/2006 36 Female 7/11/2007 Other Health Professional United States
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/10/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Lesion Other Serious 10/24/2006 Female 157 lb 7/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 7/30/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 36 Female 7/12/2007 United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 7/6/2007 58 Female 8/2/2007 Other Health Professional Germany
Primary
Secondary
Tremor Other Serious 3/10/2007 70 Female 251 lb 8/3/2007 Physician
Primary
Secondary
Concomitant
Tremor Other Serious 70 Female 8/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 3/10/2007 70 Female 8/20/2007 Physician
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Male 8/20/2007 Other Health Professional France
Primary
Concomitant
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Pharmacist Germany
Primary
Secondary
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Physician Germany
Primary
Secondary
Tremor Other Serious 5/18/2007 70 Female 8/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Other Serious 1/4/2006 35 Female 251 lb 8/29/2007 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/18/2007 70 Female 8/30/2007 United Kingdom
Primary
Concomitant
Torsade De Pointes Life Threatening 65 Female 10/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tension Other Serious 7/6/2007 Female 10/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 5/1/2007 52 Female 198 lb 10/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 5/1/2007 52 Female 198 lb 11/5/2007 Consumer United States
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 9/1/2007 79 Female 112 lb 11/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
No Therapeutic Response Other Serious 9/1/2007 79 Female 112 lb 11/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 7/1/2005 64 Female 11/19/2007 Consumer United Kingdom
Primary
Concomitant
Paraesthesia Oral Other Serious 10/26/2006 53 Female 103 lb 11/17/2007 Physician Canada
Primary
Concomitant
Bronchiectasis Other Serious 9/1/2007 79 Female 112 lb 11/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 12/26/2006 58 Female 11/16/2007 Australia
Primary
Concomitant
Urinary Retention Other Serious 5/1/2007 52 Female 198 lb 11/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 9/1/2007 79 Female 11/20/2007 United Kingdom
Primary
Concomitant
Ileal Perforation Life Threatening 12/6/2007 60 Female 1/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 12/12/2007 1/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Subdural Haematoma Hospitalization 10/3/2007 77 Female 2/1/2008 Consumer France
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 65 Female 2/1/2008 Other Health Professional France
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/12/2007 1 Female 1/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/12/2007 2/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 10/1/2007 75 Female 2/12/2008 Other Health Professional Norway
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/12/2007 69 Female 2/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Oral Pain Disability Female 143 lb 2/22/2008 Physician United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/12/2007 69 Female 2/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/12/2007 69 Female 132 lb 3/6/2008
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 3/1/2006 Female 3/14/2008 Physician United Kingdom
Primary
Concomitant
Purpura Hospitalization 11/23/2007 73 Female 3/17/2008 Physician France
Primary
Concomitant
Serum Ferritin Increased Hospitalization 2/20/2008 84 Male 4/3/2008 Sweden
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/12/2007 69 Female 4/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death Female 4/16/2008 Ireland
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 11/12/2005 94 Female 5/1/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 11/12/2005 94 Female 5/5/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Pitting Oedema Hospitalization 3/12/2008 39 Female 5/21/2008 Physician Australia
Primary
Concomitant
Vasculitis Other Serious 5/16/2008 Female 6/5/2008 Physician Sweden
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2002 63 Female 6/9/2008 Physician United Kingdom
Primary
Concomitant
Vasculitis Other Serious 5/16/2008 Female 6/9/2008 Physician Sweden
Primary
Concomitant
Suicide Attempt Hospitalization 6/21/2008 Female 6/26/2008 Physician Germany
Primary
Secondary
Suicide Attempt Hospitalization 6/21/2008 Female 7/3/2008 Other Health Professional Germany
Primary
Secondary
Contusion Other Serious Female 7/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Contusion Other Serious Female 7/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2002 63 Female 7/25/2008 Physician United Kingdom
Primary
Concomitant
Hepatic Necrosis Hospitalization 5/30/2008 Female 8/26/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/23/2008 50 Female 9/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/2/2008 63 Male 9/15/2008 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/2/2008 63 Male 9/18/2008 France
Primary
Secondary
Concomitant
Vomiting Other Serious 5/10/2006 80 Female 10/22/2008 Other Health Professional
Primary
Concomitant
Tremor Other Serious 10/8/2008 60 Female 125 lb 11/1/2008 Pharmacist Canada
Primary
Concomitant
Coronary Artery Disease Hospitalization 9/26/2008 Female 11/5/2008 Belgium
Primary
Concomitant
Coronary Artery Disease Hospitalization 9/26/2008 Female 11/12/2008 Belgium
Primary
Concomitant
Tremor Other Serious 10/8/2008 60 Female 125 lb 12/2/2008 Pharmacist Canada
Primary
Concomitant
Vomiting Other Serious 10/20/2008 46 Female 12/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Life Threatening 10/20/2008 46 Female 148 lb 12/23/2008 United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 7/2/2008 63 Male 1/20/2009 France
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/2/2008 63 Male 3/2/2009 France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/6/2009 62 Male 165 lb 4/21/2009 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/6/2009 62 Male 165 lb 5/1/2009 Physician Canada
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 4/6/2009 62 Male 5/11/2009 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 4/6/2009 62 Male 5/26/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/12/2008 78 6/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 5/1/2009 91 Female 6/11/2009 Pharmacist United Kingdom
Primary
Concomitant
Somnolence Other Serious 4/30/2009 Female 6/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Suicide Attempt Hospitalization 5/1/2009 91 Female 170 lb 7/1/2009 Pharmacist United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 1/1/2009 51 Female 188 lb 7/1/2009 Physician Germany
Primary
Concomitant
Interacting
Suicide Attempt Hospitalization 5/1/2009 91 Female 170 lb 7/7/2009 Pharmacist United Kingdom
Primary
Concomitant
Intestinal Obstruction Hospitalization 8/28/2000 70 Female 7/17/2009 Physician New Zealand
Primary
Concomitant
Tracheostomy Life Threatening 7/27/2007 Female 258 lb 7/30/2009 Physician United Kingdom
Primary
Concomitant
Rash Other Serious 7/6/2009 75 Male 139 lb 7/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 8/4/2009 Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Other Serious 4/1/2001 Male 8/5/2009 Japan
Primary
Secondary
Concomitant
Rash Other Serious 7/6/2009 75 Male 138 lb 8/6/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 6/19/2009 Female 143 lb 8/26/2009 Consumer United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 6/21/2007 Female 176 lb 9/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/7/2009 Female 104 lb 9/16/2009 Other Health Professional France
Primary
Concomitant
Weight Decreased Hospitalization 8/7/2009 Female 104 lb 9/30/2009 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/11/2009 Female 171 lb 10/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Off Label Use Life Threatening 9/30/2009 80 Female 11/2/2009 Physician United Kingdom
Primary
Concomitant
Tendon Disorder Other Serious Female 11/18/2009 Canada
Primary
Concomitant
Vomiting Hospitalization 8/11/2009 Female 171 lb 11/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/1/2005 64 Female 11/30/2009 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious Male 12/24/2009 Pharmacist
Primary
Concomitant
Osteonecrosis Other Serious 6/1/2009 74 Female 1/8/2010 Consumer Canada
Primary
Concomitant
Tremor Other Serious 5/18/2007 70 Female 1/20/2010 Physician United Kingdom
Primary
Concomitant
Spontaneous Haematoma Life Threatening 4/14/2009 Female 1/29/2010 Consumer France
Primary
Concomitant
Spontaneous Haematoma Life Threatening 4/2/2009 Female 198 lb 2/4/2010 Consumer France
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/12/2008 78 Male 196 lb 2/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data