Levothyroxine Sodium combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Haemarthrosis Hospitalization 6/6/2004 Female 1/4/2006 France
Primary
Concomitant
Tinnitus Other Serious 11/1/2005 71 Female 1/10/2006 Consumer Australia
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 5/15/2005 68 Male 218 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2005 85 Female 1/26/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Death 79 Female 2/13/2006 Canada
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 52 Male 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
Haemodialysis Other Serious 82 Female 2/13/2006 Canada
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/29/2005 79 Male 153 lb 3/6/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 5/3/2001 69 Female 179 lb 5/18/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Required Intervention 2/8/2006 Female 4/26/2006 Pharmacist United States
Primary
Concomitant
Hyperhidrosis Other Serious 48 Male 5/18/2006 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis Life Threatening 48 Male 5/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 2/1/2006 51 Female 143 lb 5/26/2006 Physician South Africa
Primary
Concomitant
Ventricular Tachycardia Hospitalization 69 Female 176 lb 6/8/2006 Canada
Primary
Concomitant
Muscular Weakness Other Serious 10/28/2005 75 Male 268 lb 6/26/2006 Pharmacist United States
Primary
Concomitant
Hypotension Life Threatening 48 Male 8/19/2006 United Kingdom
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 8/19/2006 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 80 Male 5/3/2007
Primary
Secondary
Concomitant
Rash Other Serious 3/1/2006 Female 175 lb 5/14/2007 Physician
Primary
Concomitant
Dyspnoea 72 Female 132 lb 6/22/2007 Consumer United States
Primary
Concomitant
Drug Interaction Death 82 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 80 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 58 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 77 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 1/7/2007 74 Female 8/13/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Skin Laceration Other Serious 6/1/2007 Female 172 lb 8/29/2007 Physician United States
Primary
Concomitant
Tremor Disability Female 112 lb 8/29/2007 Physician South Africa
Primary
Concomitant
Erythema 1/22/2007 81 Male 181 lb 9/20/2007 Consumer United States
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/22/2006 79 Female 5/19/2008 Physician United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 6/4/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2007 88 Female 6/16/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 74 Male 10/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 12/22/2008 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/7/2008 12/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Squamous Cell Carcinoma Other Serious 8/1/2007 Female 160 lb 1/9/2009 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 10/24/2008 Female 1/9/2009 Consumer
Primary
Concomitant
Off Label Use Hospitalization 12/26/2006 72 Female 1/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 1/1/2008 Female 1/28/2009 Consumer United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 12/1/2008 68 Female 2/2/2009 Physician Canada
Primary
Concomitant
Off Label Use Hospitalization 12/26/2006 72 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Other Serious 91 Female 2/14/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 2/17/2009 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2008 Female 110 lb 2/20/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased 2/1/2009 Male 2/20/2009 Consumer
Primary
Concomitant
Flushing 11/19/2008 Female 2/24/2009 United States
Primary
Concomitant
Flushing 2/3/2009 Male 2/24/2009 United States
Primary
Concomitant
Haemorrhage Urinary Tract Other Serious 2/1/2009 Male 179 lb 3/10/2009 Consumer United States
Primary
Secondary
Concomitant
Sciatica Other Serious 1/1/2006 Male 216 lb 3/25/2009 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 12/26/2006 72 Female 4/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 10/16/2008 69 Male 226 lb 1/12/2009 Pharmacist United States
Primary
Concomitant
Pain In Extremity Hospitalization 3/24/2009 77 Female 4/22/2009 Consumer United States
Primary
Concomitant
Myositis Hospitalization 2/1/2009 66 Male 4/29/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Mesenteric Occlusion Other Serious 73 Male 4/30/2009 Canada
Primary
Secondary
Vasculitis Gastrointestinal Other Serious 73 Male 4/30/2009 Other Health Professional France
Primary
Secondary
Therapeutic Reaction Time Decreased 12/1/2008 Male 5/1/2009 Physician
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/29/2009 77 Male 5/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sciatica Other Serious 1/1/2006 Male 216 lb 5/4/2009 Consumer United States
Primary
Secondary
Concomitant
Haemorrhage Urinary Tract Other Serious 2/1/2009 Male 179 lb 5/7/2009 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 5/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred 2/1/2009 Female 127 lb 5/28/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/12/2008 78 6/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 87 Female 6/17/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/13/2009 76 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 6/2/2009 Female 160 lb 6/25/2009 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Death 89 Female 6/21/2009 United States
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 6/25/2009 Physician United Kingdom
Primary
Concomitant
Oesophageal Achalasia Hospitalization 6/8/2009 Female 149 lb 6/30/2009 Physician United States
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 6/21/2009 74 7/10/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 72 Female 7/14/2009 Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/7/2009 72 Male 7/31/2009 United Kingdom
Primary
Concomitant
Somnolence Other Serious 91 Female 8/7/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 68 Male 8/12/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Flushing 10/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Pruritus Male 8/22/2009 United States
Primary
Concomitant
Oesophageal Achalasia Hospitalization 6/8/2009 Female 149 lb 8/20/2009 Physician United States
Primary
Concomitant
Loss Of Consciousness Life Threatening 6/12/2009 Male 219 lb 8/25/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Death 89 Female 9/3/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 46 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2006 76 Male 215 lb 9/24/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/20/2009 71 Male 9/21/2009 Pharmacist United States
Primary
Concomitant
Pericarditis Hospitalization 7/21/2009 Male 9/25/2009 Physician Switzerland
Primary
Secondary
Concomitant
Weight Increased Hospitalization 46 Male 9/18/2009 Consumer United States
Primary
Concomitant
Oesophageal Achalasia Hospitalization 6/8/2009 Female 149 lb 9/22/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 4/28/2009 82 Female 9/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 69 Female 9/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/1/2008 82 Male 10/1/2009 Physician
Primary
Concomitant
Drug Interaction Hospitalization 69 Female 138 lb 10/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 3/22/2009 50 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 68 Female 207 lb 12/10/2009 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 89 Female 12/14/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Thyroid Disorder Other Serious 4/21/2008 66 Female 137 lb 12/9/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious Male 12/24/2009 Pharmacist
Primary
Concomitant
Weight Decreased Other Serious 2/1/2009 81 Female 125 lb 12/30/2009 United States
Primary
Concomitant
Vomiting Other Serious 8/1/2007 75 Male 196 lb 1/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 1/4/2010 Consumer United States
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 10/22/2009 79 Female 115 lb 12/31/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 3/1/2008 53 Male 12/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 12/9/2009 68 Female 1/7/2010 Other Health Professional United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization Female 108 lb 1/14/2010 Other Health Professional United States
Primary
Concomitant
Haemorrhage Urinary Tract Other Serious 2/1/2009 Male 179 lb 1/14/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Hospitalization 75 Male 178 lb 1/13/2010 United States
Primary
Concomitant
Medication Error Death 91 Female 1/22/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 1/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/22/2009 79 Female 115 lb 2/2/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 3/10/2010 Physician United States
Primary
Secondary
Concomitant
Myopathy Other Serious 6/1/2006 48 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Sciatica Other Serious 1/1/2006 80 Male 220 lb 4/5/2010 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/16/2010 68 Male 234 lb 4/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Cardiac Arrest Death 86 Male 313 lb 4/13/2010 Other Health Professional United States
Primary
Concomitant
Anosmia 2/1/2009 72 Female 160 lb 3/25/2010 United States
Primary
Concomitant
Myopathy Other Serious 6/1/2006 48 Female 5/3/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 11/19/2007 71 Male 5/7/2010 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 4/16/2009 79 Male 125 lb 5/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 4/5/2010 89 Male 5/17/2010 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 12/1/2008 68 Female 6/2/2010 Physician Canada
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Hospitalization 4/5/2010 89 Male 6/3/2010 Physician United States
Primary
Concomitant
Red Blood Cell Abnormality Other Serious 4/22/2010 73 Male 6/3/2010 Other Health Professional Canada
Primary
Concomitant
Injection Site Haematoma 1/25/2010 60 Male 298 lb 5/11/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious Female 247 lb 6/11/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 1/1/2008 45 Female 6/11/2010 Lawyer United States
Primary
Concomitant
Oedema Peripheral Other Serious 4/13/2010 84 Male 6/14/2010 Other Health Professional Japan
Primary
Concomitant
Hypotension Hospitalization 2/19/2010 28 Female 119 lb 6/14/2010 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 1/13/2010 38 Male 6/15/2010 Physician United Kingdom
Primary
Concomitant
Subdural Haematoma Other Serious 12/1/2009 82 Male 190 lb 6/16/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2008 82 Male 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/21/2009 74 Male 176 lb 6/21/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Weight Decreased Other Serious 84 Female 6/22/2010 Consumer United States
Primary
Concomitant
Skin Lesion 10/26/2007 62 Female 157 lb 6/23/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 60 Female 99 lb 6/24/2010 Other Health Professional Canada
Primary
Concomitant
Oedema Peripheral Other Serious 4/13/2010 84 Male 6/28/2010 Other Health Professional Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 1/13/2010 38 Male 6/28/2010 Physician United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/5/2010 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/28/2010 81 Female 148 lb 7/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Failure Other Serious 1/1/2007 41 Female 280 lb 7/14/2010 Lawyer United States
Primary
Concomitant
Cellulitis Hospitalization 7/1/2010 76 Male 217 lb 7/13/2010 Consumer United States
Primary
Concomitant
Sunburn Other Serious 6/4/2010 57 Male 290 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mesenteric Occlusion Other Serious 73 Male 7/26/2010 Consumer Canada
Primary
Secondary
Concomitant
Hair Growth Abnormal 79 Female 125 lb 7/29/2010 United States
Primary
Secondary
Concomitant
Fatigue 7/1/2009 63 Male 7/29/2010 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/7/2010 78 Female 8/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tinea Versicolour Hospitalization 3/28/2010 82 Male 8/13/2010 Physician United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Other Serious 9/15/2008 71 Male 8/17/2010 Consumer Canada
Primary
Secondary
Concomitant

Drug Data