Levothyroxine Sodium combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 2/7/2005 68 Male 170 lb 10/31/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 12/1/2005 74 Female 1/5/2006 Canada
Primary
Concomitant
Vomiting Hospitalization 78 Female 1/12/2006 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/11/2005 84 Female 88 lb 1/23/2006 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 83 Female 153 lb 1/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 83 Female 153 lb 1/27/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 1/30/2006 United Kingdom
Primary
Concomitant
Urticaria Generalised Hospitalization 11/1/2005 38 Female 180 lb 2/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance Disability 80 Female 130 lb 2/2/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 2/6/2006 United Kingdom
Primary
Concomitant
Renal Impairment Disability 2/1/1998 65 Female 2/6/2006 Physician Japan
Primary
Concomitant
Weight Increased Life Threatening 4/22/2005 Male 254 lb 2/13/2006 United States
Primary
Concomitant
Nephritis Interstitial Other Serious 2/1/1998 65 Female 2/8/2006 Japan
Primary
Concomitant
Infusion Related Reaction 1/25/2006 62 Male 172 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/16/2005 Male 2/15/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Life Threatening 12/11/2005 84 Female 88 lb 2/13/2006 Physician Japan
Primary
Concomitant
Vaccination Complication Hospitalization 10/1/2000 72 Female 2/21/2006 Norway
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Post Vaccination Syndrome Hospitalization 10/1/2000 72 Female 2/22/2006 Norway
Primary
Concomitant
Hyperhidrosis Life Threatening 48 Male 2/23/2006 United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Hospitalization 9/29/2005 65 Male 1/11/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 3/3/2005 70 Female 2/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization Female 2/16/2006 Ireland
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 12/1/2005 74 Female 2/15/2006 Canada
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 79 Female 3/8/2006 United Kingdom
Primary
Concomitant
Hemiparesis Required Intervention 12/21/2005 63 Male 276 lb 3/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 12/1/2005 74 Female 3/7/2006 Canada
Primary
Concomitant
Mental Status Changes Hospitalization 85 Male 3/27/2006 Physician Denmark
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 1/12/2006 69 Female 4/11/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 11/27/2005 74 Female 3/24/2006 Canada
Primary
Concomitant
Rectal Haemorrhage Other Serious 12/1/2005 74 Female 3/24/2006 Canada
Primary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperhidrosis Life Threatening 48 Male 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Death 3/14/2006 62 Female 4/6/2006 Pharmacist South Africa
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 Female 4/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 4/1/2006 Male 125 lb 4/3/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 2/1/2006 Female 4/25/2006 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2005 Male 2/21/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Death 1/1/1999 79 Female 4/19/2006 Canada
Primary
Concomitant
Retinal Vascular Thrombosis Hospitalization 2/1/2004 74 Male 4/28/2006 Norway
Primary
Concomitant
Tachycardia Hospitalization 12/1/2001 63 Male 4/28/2006 Norway
Primary
Concomitant
Keratopathy Other Serious 69 Female 4/26/2006 United States
Primary
Concomitant
Haemodialysis Hospitalization 1/13/2004 82 Female 4/26/2006 Canada
Primary
Concomitant
Thrombosis Other Serious 3/3/2005 70 Female 4/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea 1/26/2006 70 Female 2/21/2006 United States
Primary
Concomitant
Incontinence Other Serious 3/21/2006 94 Female 110 lb 5/3/2006 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 8/22/2005 62 Male 148 lb 5/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Raynaud's Phenomenon Other Serious 5/12/2005 65 Female 220 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Required Intervention 4/24/2006 89 Female 161 lb 5/8/2006 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/23/2004 69 Female 179 lb 5/12/2006 Lawyer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Death 78 Female 5/9/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Prothrombin Time Ratio Decreased Life Threatening 3/21/2006 72 Female 5/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Prothrombin Time Prolonged Hospitalization 1/16/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/6/2005 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 3/3/2005 70 Female 5/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 2/14/2006 60 Male 295 lb 5/20/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Ratio Decreased Life Threatening 3/21/2006 72 Female 5/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Insomnia 8/1/2005 86 Male 192 lb 4/3/2006 Consumer United States
Primary
Concomitant
Hypocalcaemia Hospitalization 12/18/2005 71 Male 3/13/2006 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 12/1/2005 60 Female 320 lb 4/20/2006 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization 69 Female 176 lb 6/16/2006 Canada
Primary
Concomitant
Interacting
Cardiomyopathy Life Threatening 4/22/2005 Male 254 lb 6/16/2006 United States
Primary
Concomitant
Pneumonia Life Threatening 1/30/2006 78 Female 6/14/2006 Canada
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 1/30/2006 78 Female 6/19/2006 Canada
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 2/23/2006 77 Female 6/23/2006 Physician United Kingdom
Primary
Concomitant
Dyspnoea 1/27/2006 70 Female 5/19/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/24/2006 67 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/26/2006 61 Male 7/6/2006 Pharmacist United States
Primary
Concomitant
Swollen Tongue Other Serious 5/1/2005 73 Female 118 lb 6/30/2006 Canada
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 2/23/2006 77 Female 6/27/2006 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/11/2006 Pharmacist Canada
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/14/2005 41 Female 143 lb 7/13/2006 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/19/2006 81 Male 110 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 2/22/2006 69 Male 7/14/2006 Pharmacist Canada
Primary
Concomitant
Renal Failure Hospitalization 7/15/2006 57 Female 212 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Incorrect Drug Administration Duration Other Serious Female 200 lb 6/27/2006 United States
Primary
Concomitant
Unevaluable Event Hospitalization 5/12/2006 84 Male Pharmacist United States
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 7/21/2006 Physician Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Dysgeusia 52 Female 185 lb 7/12/2006 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 7/15/2006 55 Male 350 lb 7/24/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased 1/1/2005 68 Male 187 lb 8/1/2006 Consumer United States
Primary
Concomitant
Malnutrition Other Serious 9/22/2004 47 Male 99 lb 7/25/2006 Physician Japan
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 79 Female 323 lb 8/3/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 9/22/2004 47 Male 99 lb 7/31/2006 Physician Japan
Primary
Concomitant
Hypotension Life Threatening 48 Male 8/16/2006 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 8/6/2006 78 Male 119 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 50 Female 7/11/2006 United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 1/1/2002 72 Female 128 lb 8/14/2006 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 8/7/2006 86 Male 191 lb 8/18/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Other Serious 1/3/2006 79 Male 7/14/2006 Physician United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Intracranial Aneurysm Hospitalization 6/21/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 9/12/2006 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 9/13/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 6/4/2006 77 Female 93 lb 6/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 9/21/2006 United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 225 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2006 81 Female 9/26/2006 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 7/6/2006 85 Male 172 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/13/2006 77 Male 311 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Hypotension Life Threatening 48 Male 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 48 Male 10/13/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 9/1/2006 Female 130 lb 10/11/2006 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 7/4/2006 80 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 10/10/2006 United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/7/2006 Female 197 lb 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 2/14/2006 69 Female 121 lb 10/11/2006 Physician Japan
Primary
Concomitant
Neutropenic Sepsis Life Threatening 9/1/2006 78 Female 10/13/2006 United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 207 lb 10/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea 1/27/2006 70 Female 8/22/2006 United States
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/14/2006 77 Female 10/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Serotonin Syndrome Other Serious 9/23/2006 38 Female 11/3/2006 Physician United States
Primary
Concomitant
Wound Infection Other Serious 3/1/2006 60 Female 105 lb 10/30/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 Female 11/9/2006 Consumer Germany
Primary
Secondary
Concomitant
Reaction To Drug Excipients Other Serious 11/12/2005 38 Female 1/12/2006 United States
Primary
Secondary
Ventricular Tachycardia Life Threatening 5/19/2006 62 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 62 Male 11/16/2006 Consumer Japan
Primary
Concomitant
Hypotension Life Threatening 48 Male 11/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Varicose Ulceration Other Serious 8/15/2006 Female 198 lb 11/22/2006 Physician Czech Republic
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2006 76 Male 185 lb 11/8/2006 Consumer United States
Primary
Concomitant
Haemorrhage Other Serious 11/10/2006 86 Female 11/17/2006 Consumer United States
Primary
Concomitant
Renal Impairment Disability 4/7/2006 77 Male 128 lb 11/20/2006 Physician Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/28/2006 83 Male 153 lb 9/18/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 7/25/2006 86 Male 11/28/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 54 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 3/15/2006 66 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 10/12/2006 Female 12/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Hypertension Hospitalization 7/14/2005 41 Female 143 lb 11/30/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 9/23/2006 38 Female 219 lb 11/30/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 4/1/2005 Female 158 lb 12/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Intervertebral Discitis Hospitalization 6/14/2006 Female 179 lb 12/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Upper Limb Fracture Life Threatening Female 12/15/2006 Physician United Kingdom
Primary
Concomitant
Interacting
Vomiting Hospitalization 6/4/2005 61 Female 12/5/2006 Physician Sweden
Primary
Concomitant
Sepsis Syndrome Required Intervention 5/31/2006 70 Female 12/15/2006 Pharmacist United States
Primary
Concomitant
Hypotension Life Threatening 48 Male 12/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 68 Female 12/7/2006 Canada
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 12/2/2006 72 Female 232 lb 12/11/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2006 76 Male 185 lb 12/5/2006 Consumer United States
Primary
Concomitant
Renal Failure Required Intervention 5/16/2006 76 Female 12/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Shock Life Threatening 9/29/2006 66 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Xanthopsia Other Serious 62 Male 12/21/2006
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/14/2006 Physician Japan
Primary
Concomitant

Drug Data