Levothyroxine Sodium combined with Tiotropium Bromide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 9/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 3/31/2004 56 Female 225 lb 10/12/2006 Physician United States
Primary
Concomitant
Ileus Other Serious 8/10/2006 51 Female 134 lb 10/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Macular Hospitalization 2/7/2006 Male 11/6/2006 Other Health Professional Australia
Primary
Concomitant
Gastroenteritis Radiation Hospitalization 8/30/2006 50 Female 134 lb 11/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Superinfection Other Serious 1/1/2006 79 Female 154 lb 12/21/2006 Physician Germany
Primary
Concomitant
Vomiting Other Serious 8/10/2006 50 Female 134 lb 1/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gastroenteritis Radiation Hospitalization 8/30/2006 50 Female 134 lb 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/5/2006 50 Female 134 lb 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 12/1/2005 72 Female 150 lb 4/2/2007 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 3/4/2007 73 Male 5/2/2007 Greece
Primary
Concomitant
Nausea Hospitalization 12/1/2005 72 Female 150 lb 5/22/2007 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 7/11/2006 88 Male 7/17/2007
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 8/15/2007 74 Male 218 lb 8/27/2007 Consumer Germany
Primary
Concomitant
Confusional State Hospitalization 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 9/1/2007 79 Female 112 lb 11/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
No Therapeutic Response Other Serious 9/1/2007 79 Female 112 lb 11/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bronchiectasis Other Serious 9/1/2007 79 Female 112 lb 11/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bronchiectasis Other Serious 9/1/2007 79 Female 11/20/2007 United Kingdom
Primary
Concomitant
Somnolence Other Serious 9/17/2007 61 269 lb 11/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Necrosis Other Serious 11/1/2003 Female 126 lb 1/4/2008 Physician United States
Primary
Concomitant
Rash 12/17/2007 Female 303 lb 3/14/2008 United States
Primary
Secondary
Concomitant
Rash Macular 10/28/2007 Female 220 lb 3/15/2008 Consumer United States
Primary
Concomitant
Mass 1/1/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death Female 4/16/2008 Ireland
Primary
Concomitant
Confusional State Hospitalization 9/1/2007 75 Male 5/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 1/30/2008 Female 5/15/2008 Physician Canada
Primary
Concomitant
Pancreatitis Acute Hospitalization 1/25/2008 63 Female 5/29/2008 Physician Italy
Primary
Concomitant
Prostate Cancer Other Serious 8/15/2007 74 Male 218 lb 6/5/2008 Consumer Germany
Primary
Concomitant
Rash Hospitalization 6/15/2008 63 Female 7/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 6/1/2008 7/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer 6/15/2008 63 Female 7/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Death 5/12/2008 55 Female 254 lb 8/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hot Flush 4/28/2008 Female 159 lb 8/27/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/2/2008 63 Male 9/15/2008 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/2/2008 63 Male 9/18/2008 France
Primary
Secondary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/3/2008 United States
Primary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/6/2008 United States
Primary
Concomitant
Ulcer Hospitalization 63 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 5/1/2008 66 Female 170 lb 11/5/2008 Physician Spain
Primary
Concomitant
Myalgia Other Serious 6/1/2008 69 Female 121 lb 11/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 6/1/2008 69 Female 121 lb 11/11/2008 Consumer United Kingdom
Primary
Concomitant
Aphonia Other Serious 10/10/2008 76 Female 11/26/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 10/20/2008 46 Female 12/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 75 Male 213 lb 12/17/2008 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 1/1/2007 68 Female 12/19/2008 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2007 68 Female 12/29/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Life Threatening 10/20/2008 46 Female 148 lb 12/23/2008 United Kingdom
Primary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 75 Male 213 lb 1/12/2009 Physician United Kingdom
Primary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 75 Male 213 lb 1/12/2009 Physician United Kingdom
Primary
Concomitant
Pancreatitis Other Serious 1/1/2008 75 Male 213 lb 1/16/2009 Physician United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 7/2/2008 63 Male 1/20/2009 France
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/1/2008 Male 213 lb 2/6/2009 Physician United Kingdom
Primary
Concomitant
Pancreatitis Acute Other Serious 1/1/2008 75 Male 213 lb 2/12/2009 Physician United Kingdom
Primary
Concomitant
Weight Increased Hospitalization 5/1/2008 66 Female 170 lb 2/24/2009 Physician Spain
Primary
Concomitant
Septic Shock Hospitalization 7/2/2008 63 Male 3/2/2009 France
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 3/10/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Dental Caries Other Serious 1/1/2009 77 Male 3/10/2009 Other Health Professional Norway
Primary
Concomitant
Weight Decreased Life Threatening 75 Female 183 lb 3/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Hypotonia Hospitalization 10/1/2008 66 Male 163 lb 3/23/2009 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2007 68 Female 3/24/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 75 Female 183 lb 3/24/2009 Pharmacist United States
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 11/14/2008 83 Male 4/7/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Hypotonia Hospitalization 10/1/2008 66 Male 163 lb 4/27/2009 Physician Germany
Primary
Concomitant
Visual Impairment Hospitalization 2/1/2009 Female 4/28/2009 Physician Netherlands
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 6/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 6/25/2009 Physician United Kingdom
Primary
Concomitant
Gout Other Serious 3/12/2009 72 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Gout Required Intervention 3/12/2009 72 Female 6/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 75 Female 183 lb 7/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 75 Female 183 lb 8/12/2009 Pharmacist United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 3/4/2007 73 Male 8/17/2009 Greece
Primary
Concomitant
Tenderness 9/10/2008 Female 8/21/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 53 Female 159 lb 10/19/2009 Other Health Professional United States
Primary
Concomitant
Drug Toxicity Life Threatening 1/2/2009 72 Male 240 lb 11/9/2009 Pharmacist Germany
Primary
Concomitant
Interacting
Hypoglycaemia Life Threatening 6/3/2008 61 Male 231 lb 11/23/2009 Physician Belgium
Primary
Concomitant
Weight Decreased Other Serious 8/15/2005 68 Female 12/2/2009 Physician United Kingdom
Primary
Concomitant
Venous Pressure Jugular Increased Other Serious 1/30/2008 Female 12/1/2009 Physician Canada
Primary
Concomitant
Hypoglycaemia Life Threatening 6/3/2008 61 Male 231 lb 12/9/2009 Physician Belgium
Primary
Concomitant
Transaminases Increased Hospitalization 10/5/2009 76 Female 12/17/2009 Other Health Professional France
Primary
Secondary
Concomitant
Drug Toxicity Life Threatening 1/2/2009 72 Male 240 lb 1/25/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Inappropriate Antidiuretic Hormone Secretion Hospitalization 3/9/2006 Female 2/3/2010 France
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 8/15/2009 Female 214 lb 2/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 3/1/2010 74 Male 208 lb 3/30/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 60 Female 6/28/2010 Other Health Professional Denmark
Primary
Concomitant
Vomiting 1/1/2007 59 Female 165 lb 7/9/2010 Consumer United States
Primary
Concomitant
Pain 2/1/2007 67 Female 160 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 8/15/2005 68 Female 7/20/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/30/2010 79 Female 213 lb 8/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Legionella Test Positive Hospitalization 6/22/2010 60 Male 9/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 53 Female 159 lb 10/19/2010 Other Health Professional United States
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 11/4/2010 Physician Germany
Primary
Secondary
Concomitant
Drug Ineffective 12/22/2009 76 Male 260 lb 11/18/2010 Physician United States
Primary
Concomitant
Haemoptysis Other Serious 1/1/2010 70 Female 190 lb 11/19/2010 Consumer United States
Primary
Concomitant
Death Death Male 12/8/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/6/2009 69 Male 12/9/2010 Physician United States
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious 9/26/2010 48 Female 115 lb 9/27/2010 Pharmacist United States
Primary
Secondary
Concomitant
Fatigue 4/19/2010 12/21/2010 Consumer United States
Primary
Concomitant
Death Death 12/23/2010 85 Male 1/25/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 1/1/2009 71 Female 207 lb 2/8/2011 Consumer Germany
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 91 Female 154 lb 2/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious Female 154 lb 2/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 91 Female 154 lb 2/22/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 91 Female 2/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gout Other Serious 3/12/2009 72 Female 3/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acidosis Death 9/1/2010 63 Female 165 lb 3/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/22/2011 66 Male 280 lb 4/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hiccups Other Serious 3/30/2011 78 Female 123 lb 4/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hiccups Other Serious 3/30/2011 78 Female 123 lb 4/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hiccups Other Serious 3/30/2011 78 Female 123 lb 4/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hiccups Other Serious 3/30/2011 78 Female 123 lb 4/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/4/2010 66 Female 108 lb 4/22/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hiccups Other Serious 3/30/2011 78 Female 4/18/2011 United Kingdom
Primary
Concomitant
Hiccups Other Serious 3/30/2011 78 Female 123 lb 4/21/2011
Primary
Concomitant
Dyspnoea Other Serious 4/9/2011 64 Female 132 lb 5/10/2011 Other Health Professional United Kingdom
Primary
Concomitant
Skin Exfoliation Hospitalization 4/9/2011 64 Female 154 lb 5/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Tract Irritation Other Serious 1/1/2011 66 Female 6/2/2011 Consumer United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 4/9/2011 64 Female 132 lb 6/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardioactive Drug Level Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant

Drug Data