Levothyroxine Sodium combined with Sunitinib Malate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Cell Carcinoma Stage Unspecified Other Serious 1/1/2007 Female 3/15/2007 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 2/22/2007 78 Female 122 lb 5/30/2007 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/22/2007 78 Female 122 lb 5/30/2007 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/15/2007 78 Female 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2002 78 Female 121 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
Hypertension Other Serious Female 6/8/2007 Physician United States
Primary
Concomitant
Cholelithiasis Hospitalization 2/22/2007 78 Female 122 lb 6/18/2007 United States
Primary
Concomitant
Vomiting Hospitalization 2/22/2007 78 Female 122 lb 7/13/2007 United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/1/2007 Female 7/30/2007 Physician United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 1/1/2007 Female 9/6/2007 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 85 Female 12/22/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 54 Female 12/22/2007 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 56 Male 12/22/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 54 Female 1/10/2008 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 85 Female 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 56 Male 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 54 Female 2/21/2008 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 56 Male 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Microangiopathic Haemolytic Anaemia Other Serious 57 Female 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 62 Female 161 lb 6/5/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/9/2008 62 Female 172 lb 6/26/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 75 Female 9/12/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Wound Dehiscence Other Serious 8/2/2008 12/17/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/24/2008 12/18/2008 Physician Japan
Primary
Concomitant
Dehydration Hospitalization 9/13/2008 57 Male 198 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/2/2007 1/23/2009 Germany
Primary
Concomitant
Fatigue Hospitalization 7/15/2008 Female 141 lb 1/27/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/22/2008 1/28/2009 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 10/22/2008 2/9/2009 Physician France
Primary
Concomitant
Multi-organ Failure Life Threatening 2/17/2009 3/2/2009 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/24/2008 3/5/2009 Germany
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/17/2008 3/13/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 1/26/2007 3/17/2009 Physician France
Primary
Concomitant
Jaundice Hospitalization 2/8/2005 3/24/2009 Physician France
Primary
Concomitant
Microangiopathic Haemolytic Anaemia Other Serious 57 Female 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Disability 5/21/2008 3/25/2009 Physician Israel
Primary
Concomitant
Hypercalcaemia Hospitalization 4/30/2007 4/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Life Threatening 2/17/2009 4/6/2009 Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 5/21/2008 4/9/2009 Physician Israel
Primary
Concomitant
Renal Failure Death 1/1/2005 57 Female 4/16/2009 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/30/2006 4/27/2009 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/2/2009 4/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pericardial Effusion Hospitalization 6/30/2006 45 5/25/2009 Other Health Professional France
Primary
Concomitant
Pericardial Effusion Hospitalization 6/30/2006 45 5/25/2009 Physician France
Primary
Concomitant
Hypotension Hospitalization 8/20/2008 Male 136 lb 5/26/2009 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 6/2/2009 57 6/16/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/30/2006 48 Female 150 lb 6/18/2009 Consumer United States
Primary
Concomitant
Convulsion Hospitalization 10/27/2008 51 6/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/17/2008 68 6/26/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/30/2006 79 Female 150 lb 7/9/2009 Consumer United States
Primary
Concomitant
Empyema Hospitalization 6/2/2009 57 7/10/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/30/2006 79 7/10/2009 Physician Italy
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 5/20/2006 56 7/10/2009 Physician Argentina
Primary
Concomitant
Ascites Hospitalization 11/15/2007 42 7/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ascites Hospitalization 11/15/2007 42 7/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/26/2009 48 8/18/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 8/18/2009 Other Health Professional Colombia
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 185 lb 8/26/2009 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/17/2009 49 9/1/2009 Physician France
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/26/2009 48 9/23/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Disease Progression Death 2/20/2008 Female 90 lb 10/1/2009 Physician France
Primary
Secondary
Concomitant
Malignant Pleural Effusion Hospitalization 8/17/2009 49 10/7/2009 Physician France
Primary
Concomitant
Proteinuria Hospitalization 2/2/2006 56 10/14/2009 France
Primary
Concomitant
Angioedema Hospitalization 6/27/2007 66 10/26/2009 Physician Colombia
Primary
Concomitant
Respiratory Failure Hospitalization 3/14/2007 50 Female 146 lb 11/3/2009 Other Health Professional Brazil
Primary
Concomitant
Malignant Pleural Effusion Hospitalization 8/17/2009 49 Female 207 lb 11/10/2009 Physician France
Primary
Concomitant
Hypercalcaemia Hospitalization 4/30/2007 45 Female 126 lb 11/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 3/14/2007 74 Male 146 lb 11/11/2009 Other Health Professional Brazil
Primary
Concomitant
Myocardial Infarction Death 8/17/2009 57 Male 198 lb 11/13/2009 Physician Poland
Primary
Concomitant
Hypotension Hospitalization 8/16/2008 Male 136 lb 11/18/2009 Physician United States
Primary
Concomitant
Chest Pain Other Serious 63 Male 157 lb 11/25/2009 Physician United Kingdom
Primary
Concomitant
Chest Pain Other Serious 63 Male 157 lb 12/3/2009 Physician United Kingdom
Primary
Concomitant
Pyrexia Other Serious 5/26/2009 77 Male 109 lb 12/4/2009 Physician Japan
Primary
Concomitant
Hyponatraemia Hospitalization 11/22/2005 41 Male 170 lb 12/29/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 63 Male 157 lb 1/11/2010 Physician United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 184 lb 1/25/2010 Other Health Professional Colombia
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/7/2009 60 Male 185 lb 2/8/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 2/11/2008 60 Female 121 lb 2/9/2010 Other Health Professional Australia
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 184 lb 3/15/2010 Other Health Professional Colombia
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 185 lb 3/29/2010 Consumer United States
Primary
Secondary
Concomitant
Death Hospitalization 3/16/2010 58 Male 166 lb 3/29/2010 Physician United Kingdom
Primary
Concomitant
Subileus Hospitalization 1/19/2006 62 Female 192 lb 3/29/2010 Other Health Professional Germany
Primary
Concomitant
Pleural Effusion Hospitalization 6/18/2008 58 Male 262 lb 4/7/2010 Physician Germany
Primary
Concomitant
Death Hospitalization 3/16/2010 58 Male 165 lb 4/9/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 5/1/2009 75 Female 2/15/2010 Physician United States
Primary
Concomitant
Vertigo Hospitalization 9/15/2008 74 Female 157 lb 4/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 8/24/2008 74 Female 157 lb 4/27/2010 Germany
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 4/6/2006 45 Male 4/27/2010 Other Health Professional France
Primary
Concomitant
Proteinuria Hospitalization 2/7/2006 56 Male 223 lb 5/5/2010 France
Primary
Concomitant
Renal Failure Chronic Hospitalization 58 Male 165 lb 5/5/2010 Physician United Kingdom
Primary
Concomitant
Sepsis Other Serious 2/11/2008 60 Female 121 lb 5/28/2010 Other Health Professional Australia
Primary
Concomitant
Hepatitis Hospitalization 8/2/2006 75 Female 187 lb 6/9/2010 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 10/18/2006 67 Male 122 lb 6/23/2010 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 5/22/2010 72 Female 134 lb 7/8/2010 Physician Germany
Primary
Secondary
Concomitant
Atrioventricular Block Hospitalization 12/13/2006 54 Female 174 lb 7/9/2010 Physician Italy
Primary
Concomitant
Rhabdomyolysis Death 1/11/2007 65 Female 110 lb 7/12/2010 Physician France
Primary
Concomitant
Rhabdomyolysis Death 1/11/2007 65 Female 110 lb 7/16/2010 Physician France
Primary
Concomitant
Electrocardiogram Abnormal Hospitalization 7/6/2010 46 Female 112 lb 7/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocarditis Hospitalization 7/6/2010 46 Female 112 lb 7/28/2010 Other Health Professional Germany
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/22/2009 70 Male 7/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Yellow Skin Other Serious Female 7/27/2010 Physician Austria
Primary
Concomitant
Pyrexia Hospitalization 5/22/2010 72 Female 134 lb 8/3/2010 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/20/2010 73 Female 132 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 6/8/2010 61 Female 8/10/2010 Physician Spain
Primary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 8/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/22/2010 72 Female 134 lb 8/19/2010 Consumer United States
Primary
Secondary
Concomitant
Metastatic Renal Cell Carcinoma Hospitalization 5/25/2007 70 Female 88 lb 8/20/2010 Other Health Professional Canada
Primary
Concomitant
Tremor Life Threatening 8/8/2010 64 Male 8/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 12/26/2005 60 Female 172 lb 9/2/2010 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 5/27/2010 64 Female 9/7/2010 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 7/6/2006 45 Male 157 lb 9/14/2010 Physician France
Primary
Concomitant
Ascites Hospitalization 11/15/2007 42 Male 9/14/2010 Physician United Kingdom
Primary
Concomitant
Sepsis Other Serious 2/28/2008 66 Male 205 lb 9/16/2010 Physician Germany
Primary
Concomitant
Myocarditis Hospitalization 7/6/2010 46 Female 112 lb 9/17/2010 Other Health Professional Germany
Primary
Concomitant
Tracheal Fistula Hospitalization 12/1/2009 47 Male 130 lb 9/20/2010 Physician France
Primary
Concomitant
Pleural Effusion Other Serious 5/27/2010 64 Female 9/22/2010 Physician Germany
Primary
Secondary
Concomitant
Gastrointestinal Stromal Tumour Hospitalization 11/15/2007 42 Male 9/30/2010 Physician United Kingdom
Primary
Concomitant
Myocarditis Hospitalization 7/6/2010 46 Female 112 lb 10/13/2010 Other Health Professional Germany
Primary
Concomitant
Renal Failure Other Serious 1/4/2008 65 Male 10/18/2010 Physician Israel
Primary
Concomitant
Renal Failure Chronic Hospitalization 3/13/2010 58 Male 165 lb 10/20/2010 Physician United Kingdom
Primary
Concomitant
Bursitis Hospitalization 4/4/2005 60 Male 10/28/2010 Other Health Professional Australia
Primary
Concomitant
Renal Failure Life Threatening 4/2/2007 55 Male 198 lb 11/5/2010 Physician Germany
Primary
Concomitant
Mucosal Inflammation Other Serious 4/4/2006 59 Female 159 lb 11/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Confusional State Hospitalization 5/10/2008 63 Male 11/24/2010 Australia
Primary
Secondary
Concomitant
Thyroid Cancer Other Serious 11/24/2009 59 Male 143 lb 11/24/2010 Physician France
Primary
Concomitant
Thyroid Cancer Hospitalization 11/24/2009 59 Male 143 lb 11/29/2010 Physician France
Primary
Concomitant
Wound Haemorrhage Hospitalization 10/28/2010 65 Female 11/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/12/2006 53 Male 12/17/2010 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 4/21/2007 59 Female 139 lb 1/13/2011 Physician Sweden
Primary
Concomitant
Pneumonia Hospitalization 1/11/2011 51 Male 130 lb 1/14/2011 Other Health Professional United States
Primary
Concomitant
Fatigue Hospitalization 1/12/2011 51 Male 130 lb 1/24/2011 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 7/12/2006 53 Male 2/8/2011 Physician Germany
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 184 lb 4/18/2011 Other Health Professional Colombia
Primary
Secondary
Concomitant
Thyroiditis Other Serious 58 Female 5/5/2011 Other Health Professional Japan
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 185 lb 5/13/2011 Consumer United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious 4/27/2011 70 Female 170 lb 5/23/2011 Physician Germany
Primary
Concomitant
Intestinal Obstruction Hospitalization 7/23/2009 74 Male 148 lb 5/30/2011 Physician Japan
Primary
Concomitant
Cholecystitis Acute Hospitalization 5/5/2011 46 Male 6/2/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Neoplasm Malignant Hospitalization 8/9/2010 63 Female 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 3/31/2011 71 Female 6/8/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 10/18/2010 53 Male 141 lb 6/23/2011 Physician Japan
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious Male 6/28/2011 Physician Japan
Primary
Concomitant
Hyponatraemia Hospitalization 8/7/2009 60 Male 184 lb 7/20/2011 Other Health Professional Colombia
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 3/23/2011 59 Male 134 lb 8/16/2011 Physician Japan
Primary
Concomitant
Convulsion Other Serious 12/19/2010 59 Male 128 lb 8/17/2011 Physician Japan
Primary
Concomitant
Exposed Bone In Jaw Other Serious Male 240 lb 8/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Impaired Healing Life Threatening Male 136 lb 8/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 7/11/2011 81 Female 104 lb 8/29/2011 Physician Japan
Primary
Concomitant

Drug Data