Levothyroxine Sodium combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 11/4/2005 48 Female 175 lb 1/16/2006 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious 11/4/2005 72 Female 97 lb 1/18/2006 Physician Japan
Primary
Secondary
Concomitant
Vitamin B Complex Deficiency Hospitalization 6/1/2001 64 Female 351 lb 1/23/2006 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Hypertension Hospitalization 1/10/2006 58 Male 1/30/2006 Physician United States
Primary
Concomitant
Somnolence Life Threatening 11/21/2005 85 Female 143 lb 1/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 52 Male 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
Haemodialysis Other Serious 82 Female 2/13/2006 Canada
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Shock Other Serious 11/4/2005 72 Female 97 lb 2/23/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperkalaemia Required Intervention 3/6/2006 79 Male 184 lb 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Carbohydrate Antigen 15-3 Increased Other Serious 1/1/2006 57 Female 180 lb 3/24/2006 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/22/2005 41 Male 170 lb 3/20/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/14/2006 88 Female 132 lb 4/5/2006 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 3/2/2006 54 Female 4/10/2006 Physician Germany
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 2/14/2006 69 Female 121 lb 4/4/2006 Physician Japan
Primary
Concomitant
Death Death 3/1/2006 51 Female 4/12/2006 United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 12/6/2005 67 Female 4/24/2006 Physician Italy
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 4/13/2006 76 Male 160 lb 4/18/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2005 Male 2/21/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 12/13/2005 56 Male 220 lb 4/24/2006 Germany
Primary
Concomitant
Wheezing Other Serious 63 Male 4/25/2006 Pharmacist United States
Primary
Concomitant
Haemodialysis Hospitalization 1/13/2004 82 Female 4/26/2006 Canada
Primary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Death Death 3/28/2006 51 Female 5/1/2006 United States
Primary
Concomitant
Vertigo Hospitalization 2/14/2006 88 Female 4/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 11/20/2005 58 Female 113 lb 11/22/2005 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/21/2005 41 Male 170 lb 5/16/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 47 Female 123 lb 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 8/17/2005 33 Female 97 lb 5/31/2006 Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 6/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 63 Male 6/6/2006 Pharmacist United States
Primary
Concomitant
Carbohydrate Antigen 15-3 Increased 1/1/2006 57 Female 180 lb 6/20/2006 Physician United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 12/6/2005 67 Female 6/27/2006 Physician Italy
Primary
Secondary
Concomitant
Blood Potassium Decreased Hospitalization 5/5/2006 Female 229 lb 7/6/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/28/2005 58 Male 7/20/2006 Japan
Primary
Concomitant
Somnolence 5/8/2006 73 Female 187 lb 6/9/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/9/2005 46 Male 1/13/2006 United States
Primary
Concomitant
Vomiting Hospitalization 4/3/2006 90 Female 7/26/2006 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 54 Female 90 lb 7/26/2006 Physician France
Primary
Concomitant
Arthralgia 5/1/2005 68 Female 187 lb 8/1/2006 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 2/1/2006 75 Male 150 lb 8/4/2006 Physician Germany
Primary
Concomitant
Hyperkalaemia Hospitalization 4/9/2006 78 Female 8/3/2006 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/4/2006 90 Female 8/2/2006 France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/1/2006 63 Female 141 lb 8/10/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 54 Female 90 lb 8/11/2006 Physician France
Primary
Concomitant
Oedema Hospitalization 1/31/2006 37 Female 8/17/2006 Germany
Primary
Concomitant
Visual Disturbance Other Serious 7/1/2006 54 Male 220 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 8/25/2006 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 7/4/2006 54 Male 220 lb 8/28/2006 Other Health Professional United States
Primary
Concomitant
Sedation 2/1/2006 83 Male 9/6/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/1/2006 France
Primary
Concomitant
Neutropenia Hospitalization 1/1/2002 65 Female 137 lb 9/8/2006 Other Health Professional France
Primary
Secondary
Vomiting Other Serious 54 Female 90 lb 9/1/2006 France
Primary
Concomitant
Pulmonary Hypertension Hospitalization 1/31/2006 37 Female 9/6/2006 Physician Germany
Primary
Concomitant
Pain In Extremity Hospitalization 1/11/2006 65 Female 9/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 9/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/19/2006 France
Primary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/25/2006 Physician France
Primary
Concomitant
Rectal Haemorrhage Other Serious 63 Female 10/3/2006 Physician Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 8/1/2006 53 Male 132 lb 9/18/2006 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 2/1/2006 75 Male 148 lb 10/10/2006 Physician Germany
Primary
Concomitant
Peripheral Ischaemia Hospitalization 12/6/2005 67 Female 10/10/2006 Physician Italy
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/7/2006 Female 197 lb 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 2/14/2006 69 Female 121 lb 10/11/2006 Physician Japan
Primary
Concomitant
Nodal Rhythm Hospitalization 9/25/2006 80 Female 10/16/2006 Physician Poland
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious 8/28/2006 1 Male 15 lb 10/20/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Hospitalization 9/1/2006 79 Female 200 lb 10/25/2006 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 3/1/2006 60 Female 105 lb 10/30/2006 Physician United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 12/9/2005 67 Female 11/13/2006 Physician Italy
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/7/2006 Female 197 lb 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/22/2006 83 Female 11/10/2006 Physician France
Primary
Secondary
Concomitant
Reflux Oesophagitis Other Serious 2/6/2004 48 Male 11/9/2006 France
Primary
Secondary
Concomitant
Sedation Other Serious 1/1/2006 76 Female 175 lb 11/9/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2003 51 Female 165 lb 11/22/2006 Physician France
Primary
Secondary
Pigmentation Disorder Hospitalization 7/18/2006 77 Female 103 lb 12/4/2006 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 1/1/2006 76 Female 175 lb 12/1/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/22/2005 41 Male 170 lb 12/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Pigmentation Disorder Hospitalization 7/18/2006 77 Female 103 lb 12/15/2006 Physician Japan
Primary
Concomitant
Superinfection Other Serious 1/1/2006 79 Female 154 lb 12/21/2006 Physician Germany
Primary
Concomitant
Vomiting Other Serious 5/1/2006 28 Female 227 lb 12/21/2006 Consumer United States
Primary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 12/18/2006 Other Health Professional Netherlands
Primary
Concomitant
Pallor Hospitalization 10/15/2006 84 Female 12/19/2006 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Required Intervention 7/11/2006 74 Female 177 lb 7/15/2006 Pharmacist United States
Primary
Concomitant
Abdominal Pain 7/30/2006 73 Female 140 lb 10/24/2006 United States
Primary
Concomitant
Headache 9/2/2006 76 Female 202 lb 10/24/2006 United States
Primary
Concomitant
Oral Mucosal Blistering 1/1/2005 54 Female 164 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension 6/1/2005 34 Female 165 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 11/22/2005 41 Male 170 lb 1/17/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Haemorrhage Intracranial Other Serious 6/2/2006 Male 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/14/2006 80 Male 240 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Pneumonia Other Serious Female 132 lb 2/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 12/8/2005 73 Male 1/30/2007 United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/10/2006 Male 215 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Kidney Infection 8/1/2006 56 Female 10/16/2006 Consumer United States
Primary
Concomitant
Nausea Hospitalization 9/25/2006 80 Female 2/12/2007 Poland
Primary
Secondary
Concomitant
Polymyalgia Rheumatica Required Intervention 7/1/2006 59 Female 159 lb 2/21/2007 Other Health Professional Netherlands
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 2/20/2007 United States
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 2/1/2007 73 Female 3/13/2007 Consumer United States
Primary
Concomitant
Fatigue Hospitalization 1/17/2007 70 Female 159 lb 3/19/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 10/1/2006 82 3/19/2007 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/19/2005 63 Male 3/26/2007 Pharmacist Germany
Primary
Secondary
Concomitant
Ulcerative Keratitis Other Serious 3/1/2007 Female 122 lb 3/26/2007 Pharmacist United Kingdom
Primary
Concomitant
Rectal Prolapse Hospitalization 1/1/2006 79 Female 3/26/2007 Consumer United States
Primary
Concomitant
Fatigue Hospitalization 1/17/2007 70 Female 159 lb 4/5/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/12/2006 80 Male 162 lb 3/23/2007 Pharmacist United States
Primary
Concomitant
Swelling Face Other Serious 10/26/2006 64 Female 4/9/2007 United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/1/2006 78 Male 4/17/2007 Consumer United Kingdom
Primary
Concomitant
Tenderness Hospitalization 4/12/2007 Female 300 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Rectal Prolapse Hospitalization 5/30/2006 79 Female 4/16/2007 Consumer United States
Primary
Concomitant
Ulcerative Keratitis 3/1/2007 Female 122 lb 4/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious Female 200 lb 4/27/2007 Physician United States
Primary
Concomitant
Interacting
Dermatosis 77 Female 5/3/2007 Netherlands
Primary
Concomitant
Renal Impairment Hospitalization 3/12/2007 77 Female 4/26/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/12/2007 77 Female 4/28/2007 United Kingdom
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Other Serious 3/24/2007 48 Female 5/2/2007 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 11/1/2006 52 Male 320 lb 1/23/2007 Physician United States
Primary
Concomitant
Sinusitis Other Serious 8/3/2006 66 Female 5/4/2007 Physician Austria
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 3/1/2007 Female 149 lb 5/14/2007 Consumer United States
Primary
Concomitant
Skin Lesion Other Serious 77 Female 5/3/2007 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Hospitalization 1/27/2007 81 Male 5/11/2007 France
Primary
Concomitant
Asthenia Hospitalization 3/22/2007 Male 153 lb 5/10/2007 Pharmacist United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 3/19/2007 70 Male 5/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Other Serious 11/1/2006 78 Male 218 lb 5/24/2007 Consumer United Kingdom
Primary
Concomitant
White Blood Cells Urine Positive Other Serious 3/24/2007 49 Female 178 lb 5/18/2007 United States
Primary
Concomitant
Pneumonia Hospitalization 11/25/2006 42 Female 148 lb 5/24/2007 Other Health Professional Japan
Primary
Concomitant
Euphoric Mood 12/6/2006 52 Female 3/13/2007 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 3/10/2007 Female 115 lb 6/11/2007 Physician France
Primary
Concomitant
Syncope Other Serious 3/1/2007 78 Male 218 lb 6/11/2007 Consumer United Kingdom
Primary
Concomitant
Vasospasm Hospitalization 84 Female 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Fluctuation Other Serious 1/1/2007 Female 6/13/2007 United States
Primary
Concomitant
Vomiting Other Serious 3/25/2006 Female 115 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2004 Male 159 lb 6/22/2007 Other Health Professional United States
Primary
Concomitant
Renal Impairment Hospitalization 3/1/2005 81 Female 6/27/2007 United Kingdom
Primary
Concomitant
Vitreous Haemorrhage Other Serious 7/4/2006 Male 220 lb 7/5/2007 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2007 46 Female 181 lb 7/6/2007 Consumer United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 7/2/2007 Female 208 lb 7/13/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Other Serious 7/16/2007 Female 280 lb 7/27/2007 United States
Primary
Concomitant
Loss Of Consciousness Disability 4/14/2007 59 Male 243 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 7/4/2006 Male 220 lb 8/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 6/2/2006 69 Female 8/1/2007 United States
Primary
Concomitant
Malformation Venous Death 63 Female 7/6/2007 New Zealand
Primary
Concomitant
Sudden Death Death 3/13/2007 63 Female 7/24/2007 New Zealand
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/1/1998 Male 8/17/2007 Lawyer United States
Primary
Secondary
Concomitant
Postpericardiotomy Syndrome Hospitalization 1/4/2007 1 Female 8/15/2007 Physician Japan
Primary
Concomitant

Drug Data