Levothyroxine Sodium combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Hypertension Hospitalization 12/13/2005 56 Male 1/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 3/28/2006 France
Primary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 4/13/2006 France
Primary
Concomitant
Bundle Branch Block Right Hospitalization 4/26/2006 69 Male 225 lb 5/8/2006 Other Health Professional Germany
Primary
Concomitant
Pneumonia Other Serious 4/1/2006 36 Female 5/26/2006 Consumer United States
Primary
Concomitant
Hypoglycaemia Death 79 Male 231 lb 1/10/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Hypoglycaemia Death 79 Male 231 lb 2/6/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Death 1/13/2007 Male 121 lb 2/21/2007 United States
Primary
Secondary
Concomitant
Tenderness Hospitalization 4/12/2007 Female 300 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Medication Error 1/1/2006 69 Male 230 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/5/2005 12/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Medication Error 1/1/2006 69 Male 230 lb 4/23/2007 United States
Primary
Secondary
Concomitant
Toothache 8/4/2006 50 Female 317 lb 9/20/2007 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/12/2008 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/13/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 4/9/2008 France
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/21/2008 Female 146 lb 6/17/2008 France
Primary
Concomitant
Death Death 2/20/2008 Female 90 lb 6/24/2008 France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/21/2008 Female 146 lb 7/8/2008 France
Primary
Concomitant
Rhabdomyolysis Other Serious 6/1/2008 73 Female 7/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Malaise Life Threatening 7/22/2008 69 Female 8/19/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/3/2008 59 Male 156 lb 9/10/2008 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 86 Female 10/8/2008
Primary
Secondary
Concomitant
Enterocolitis Infectious Hospitalization 5/21/2008 Female 126 lb 11/3/2008 France
Primary
Concomitant
Malaise Hospitalization 4/7/2008 76 Female 86 lb 12/23/2008 Physician Japan
Primary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 1/30/2008 Female 213 lb 1/9/2009 Physician United States
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2009 Male 157 lb 2/4/2009 Other Health Professional Germany
Primary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2009 Male 157 lb 2/9/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Urosepsis Hospitalization 10/14/2008 75 Female 135 lb 2/18/2009 Pharmacist United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 Female 213 lb 3/9/2009 Physician United States
Primary
Concomitant
Pancytopenia Life Threatening 3/24/2009 60 Female 4/27/2009 Physician United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/29/2009 74 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/29/2009 74 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 10/1/2008 Female 6/30/2009 United States
Primary
Concomitant
Dizziness 4/1/2008 Male 6/30/2009 United States
Primary
Concomitant
Hepatic Failure Death Female 7/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Baby Other Serious Female 7/16/2009 Physician Sweden
Primary
Concomitant
Renal Failure Other Serious Female 174 lb 7/16/2009 Physician Sweden
Primary
Concomitant
Malaise 8/18/2008 Female 142 lb 7/23/2009 Other Health Professional United States
Primary
Concomitant
Peritonitis Bacterial Other Serious 1/1/2009 59 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 10/1/2007 63 Female 1/11/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 61 Male 3/17/2010 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2010 65 Female 3/25/2010 Consumer United States
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 1/23/2010 Female 3/29/2010 Physician France
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 10/22/2007 63 Female 4/7/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 10/20/2009 69 Male 174 lb 4/26/2010 Physician Chile
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/14/2009 80 Female 5/25/2010 Physician United States
Primary
Secondary
Concomitant
Headache 3/27/2010 70 Male 5/26/2010 United States
Primary
Concomitant
Dyspnoea Hospitalization 5/21/2010 89 Female 6/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 9/1/2007 61 Male 165 lb 6/17/2010 Lawyer United States
Primary
Concomitant
Dyspnoea Hospitalization 5/21/2010 89 Female 6/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Expired Drug Administered 2/12/2010 64 Female 210 lb 6/30/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 81 Male 7/2/2010 Other Health Professional Australia
Primary
Concomitant
Respiratory Failure Other Serious 4/10/2010 67 Male 155 lb 6/25/2010 United Kingdom
Primary
Concomitant
Restrictive Cardiomyopathy Hospitalization 10/20/2009 69 Male 174 lb 7/9/2010 Physician Chile
Primary
Secondary
Concomitant
Weight Increased 2/1/2008 44 Male 7/19/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 81 Male 7/20/2010 Other Health Professional Australia
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 81 Male 7/29/2010 Other Health Professional Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 6/8/2010 65 Male 174 lb 8/6/2010 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 7/15/2009 81 Male 9/3/2010 Other Health Professional Australia
Primary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Status Epilepticus Other Serious 9/1/2007 61 Male 165 lb 9/22/2010 Lawyer United States
Primary
Concomitant
Vision Blurred Death 6/1/2007 12/6/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2011 74 Female 2/23/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Death 8/1/2010 87 Female 2/25/2011 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Other Serious 2/17/2008 59 Female 3/23/2011 Lawyer United States
Primary
Concomitant
Depression Other Serious 65 Male 209 lb 3/29/2011 Lawyer United States
Primary
Concomitant
Anxiety Death 65 Male 209 lb 3/29/2011 Lawyer United States
Primary
Concomitant
Renal Impairment Other Serious 2/6/2004 62 Female 126 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 2/6/2004 62 Female 126 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Deep Vein Thrombosis Death 8/1/2010 87 Female 3/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/22/2011 60 Female 203 lb 4/21/2011 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 11/12/2009 67 Female 273 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Oliguria Hospitalization 11/12/2009 67 Female 273 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Blood Count Abnormal Other Serious 4/19/2011 71 Female 5/10/2011 Consumer United States
Primary
Concomitant
Electrocardiogram T Wave Abnormal Other Serious 3/17/2009 66 Female 273 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/17/2005 65 Female 157 lb 5/17/2011 Consumer United States
Primary
Concomitant
Syncope Other Serious 3/22/2011 85 Male 5/19/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 2/22/2011 60 Female 203 lb 5/20/2011 Physician Australia
Primary
Concomitant
Mental Status Changes Other Serious 11/12/2009 67 Female 273 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Joint Swelling 4/1/2011 76 Female 130 lb 5/26/2011 Consumer United States
Primary
Concomitant
Headache 10/21/2010 81 Male 160 lb 5/26/2011 Consumer United States
Primary
Concomitant
Uterine Cancer Other Serious Female 249 lb 6/8/2011 Pharmacist United States
Primary
Concomitant
Pain Death 2/11/2006 65 Male 209 lb 6/8/2011 Consumer United States
Primary
Concomitant
Lymphocele Other Serious 1/28/2011 62 Male 198 lb 6/9/2011 Physician France
Primary
Secondary
Concomitant
Death Other Serious 57 Female 176 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Anaemia Other Serious 4/29/2011 69 Male 133 lb 6/24/2011 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 12/31/2004 70 Male 165 lb 6/24/2011 Other Health Professional United States
Primary
Concomitant
Fear Of Death Other Serious 11/11/2004 65 Male 185 lb 6/30/2011 Physician United States
Primary
Concomitant
Shock Hospitalization 71 Female 6/20/2011 United States
Primary
Concomitant
Hypertension Other Serious Male 185 lb 6/30/2011 Consumer United States
Primary
Concomitant
Pneumonia Fungal Death 5/29/2007 47 Male 119 lb 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Injury Other Serious 65 Male 185 lb 7/8/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 8/22/2007 63 Male 291 lb 7/21/2011 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/1/2009 64 Male 230 lb 7/13/2011 Physician United States
Primary
Concomitant
Pain Other Serious 12/31/2004 70 Male 165 lb 8/16/2011 Other Health Professional United States
Primary
Concomitant
Bronchitis Other Serious 6/22/2010 56 Female 8/29/2011 Other Health Professional Japan
Primary
Secondary
Infection Death 8/21/2010 48 Female 95 lb 9/1/2011 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 56 Female 9/2/2011 Other Health Professional Japan
Primary
Concomitant
Hospice Care Life Threatening Male 9/2/2011 Physician United States
Primary
Concomitant
Hypertension Other Serious Male 185 lb 9/14/2011 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 9/12/2011 55 Female 95 lb 9/23/2011 Physician Japan
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Death 1/1/2011 74 Female 9/26/2011 Other Health Professional Japan
Primary
Concomitant
Device Related Sepsis Death 9/12/2011 55 Female 95 lb 9/27/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/12/2011 55 Female 95 lb 10/3/2011 Physician Japan
Primary
Secondary
Concomitant
Vasodilatation Hospitalization 3/17/2009 66 Female 273 lb 10/18/2011 Physician United States
Primary
Secondary
Concomitant
Haemodynamic Instability Other Serious 11/12/2009 67 Female 273 lb 10/24/2011 Physician United States
Primary
Secondary
Concomitant
Oral Cavity Fistula Other Serious 7/1/2009 42 Male 159 lb 10/26/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 1/1/2011 71 Male 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Blood Pressure Systolic Increased Hospitalization 89 Male 10/28/2011 Other Health Professional United States
Primary
Concomitant
Periorbital Oedema Hospitalization 89 Male 11/3/2011 United States
Primary
Concomitant
Creatinine Renal Clearance Decreased Other Serious 89 Male 11/7/2011 Other Health Professional United States
Primary
Concomitant
Hypercholesterolaemia Hospitalization 5/1/2008 41 Female 225 lb 11/9/2011 Physician United States
Primary
Concomitant
Hyperthermia Hospitalization 1/28/2011 62 Male 176 lb 11/14/2011 France
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 2/1/2010 42 Male 159 lb 12/8/2011 Physician Japan
Primary
Secondary
Concomitant
Confusional State Hospitalization 58 Female 12/9/2011 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 11/18/2011 88 Male 125 lb 12/14/2011 Pharmacist United States
Primary
Concomitant
Neurotoxicity Hospitalization 89 Male 12/21/2011 Other Health Professional United States
Primary
Secondary
Bipolar I Disorder Hospitalization 11/30/2011 64 Female 134 lb 12/22/2011 Physician United States
Primary
Concomitant
Device Ineffective Other Serious 21 Female 295 lb 12/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Death 12/20/2011 58 Female 229 lb 1/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Dental Fistula Other Serious 7/1/2009 42 Male 159 lb 1/9/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Thyroid Stimulating Hormone Increased Other Serious 2/26/2009 21 Female 295 lb 1/10/2012 Consumer United Kingdom
Primary
Concomitant
Interacting
Neutropenic Infection Death 12/20/2011 58 Female 229 lb 1/12/2012 Physician United States
Primary
Secondary
Concomitant
Blood Thyroid Stimulating Hormone Increased Other Serious 1/1/2008 21 Female 295 lb 1/17/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Failure Chronic Other Serious 9/1/2003 45 Female 1/18/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Infection Death 4/7/2011 75 Female 1/19/2012 Other Health Professional Japan
Primary
Concomitant
Adrenal Insufficiency Hospitalization 11/1/2011 58 Male 1/20/2012 Other Health Professional France
Primary
Secondary
Concomitant
Deafness Other Serious 96 Male 172 lb 1/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deafness Other Serious 96 Male 172 lb 1/17/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Influenza Like Illness 3/17/2011 47 Female 1/28/2012 Physician United States
Primary
Concomitant
Pernicious Anaemia Other Serious 9/1/2003 45 Female 2/7/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Leukopenia Hospitalization 1/6/2012 4 Female 2/21/2012 Physician Germany
Primary
Concomitant
Renal Transplant Other Serious 10/30/2009 2/28/2012 Consumer United States
Primary
Concomitant
Metastatic Renal Cell Carcinoma Death 11/17/2011 75 Male 140 lb 3/1/2012 Physician Japan
Primary
Concomitant
Metastatic Renal Cell Carcinoma Death 11/17/2011 75 Male 140 lb 3/20/2012 Physician Japan
Primary
Concomitant
5Q Minus Syndrome Other Serious 1/10/2012 68 Male 173 lb 3/21/2012 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 2/1/2012 76 Male 204 lb 3/27/2012 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 8/18/2011 66 Male 3/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Hospitalization 7/1/2009 42 Male 159 lb 4/3/2012 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 8/21/2010 48 Female 95 lb 4/6/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Lymphocele Other Serious 1/28/2011 62 Male 176 lb 4/11/2012 France
Primary
Secondary
Concomitant
Malaise Other Serious 2/1/2012 76 Male 204 lb 4/16/2012 Physician United States
Primary
Secondary
Concomitant
5Q Minus Syndrome Other Serious 1/10/2012 68 Male 173 lb 4/18/2012 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 79 Female 160 lb 4/23/2012 Consumer United States
Primary
Concomitant

Drug Data