Levothyroxine Sodium combined with Rebif

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Spastic Paralysis Required Intervention 11/15/2005 53 Female 198 lb 1/27/2006 France
Primary
Concomitant
Tremor Other Serious 3/1/2006 49 Male 4/12/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 12/31/2004 44 Female 5/24/2006 Other Health Professional United States
Primary
Concomitant
Autoimmune Hepatitis Hospitalization 5/26/2006 43 Female 1/19/2007 Canada
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/1/2007 53 Female 3/27/2007 United States
Primary
Concomitant
Convulsion Other Serious 4/1/2007 55 Female 7/9/2007 United States
Primary
Concomitant
Large Intestine Perforation Hospitalization 6/1/2007 64 Male 164 lb 7/20/2007 Other Health Professional United States
Primary
Concomitant
Speech Disorder Other Serious 24 Female 9/10/2007 Consumer Brazil
Primary
Concomitant
Headache Other Serious 8/1/2007 40 Female 230 lb 10/2/2007 United States
Primary
Secondary
Concomitant
Pharyngeal Injury Hospitalization 9/6/2007 48 Female 300 lb 11/1/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 6/16/2007 52 Female 242 lb 11/5/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/13/2007 54 Female 214 lb 11/27/2007 United States
Primary
Concomitant
Wound Infection Hospitalization 1/1/2007 41 Female 12/11/2007 United States
Primary
Concomitant
Muscle Spasms Hospitalization 10/1/2007 27 Female 204 lb 12/14/2007 Physician United States
Primary
Concomitant
Wheezing Other Serious 8/1/2007 56 Female 200 lb 12/18/2007 Physician United States
Primary
Concomitant
Syncope Vasovagal Other Serious 12/4/2007 52 Female 150 lb 1/25/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2004 42 Female 190 lb 1/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neuralgia Hospitalization 1/1/2007 67 Female 182 lb 3/5/2008 Consumer United States
Primary
Concomitant
Skin Necrosis Other Serious 2/28/2008 48 Female 147 lb 3/10/2008 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 6/1/2007 65 Male 164 lb 3/14/2008 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 2/1/2008 53 Female 3/21/2008 United States
Primary
Concomitant
Thrombosis Hospitalization 3/27/2008 68 Female 130 lb 4/22/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 53 Female 112 lb 5/5/2008 United States
Primary
Concomitant
Neuralgia Hospitalization 11/1/2007 67 Female 182 lb 5/28/2008 United States
Primary
Concomitant
Pain Hospitalization 1/1/2007 45 Female 191 lb 6/19/2008 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/1/2008 52 Female 125 lb 6/23/2008 United States
Primary
Concomitant
Headache Other Serious 8/1/2007 40 Female 229 lb 5/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulse Absent Other Serious 4/1/2008 58 Female 140 lb 7/15/2008 United States
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 6/10/2008 31 Male 255 lb 7/29/2008 Consumer United States
Primary
Concomitant
Spinal Disorder Hospitalization 7/7/2008 63 Female 136 lb 8/8/2008 Physician United States
Primary
Concomitant
Retinal Detachment Other Serious 1/1/2007 61 Female 150 lb 8/11/2008 United States
Primary
Concomitant
Retinal Detachment Other Serious 1/1/2007 61 Female 150 lb 8/26/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 53 Female 112 lb 8/30/2008 United States
Primary
Concomitant
Off Label Use Other Serious 1/31/2008 50 Female 155 lb 9/16/2008 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 7/1/2008 46 Female 9/30/2008 United States
Primary
Concomitant
Wrist Fracture Hospitalization 4/24/2008 52 Female 9/29/2008 United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 1/1/2008 40 Female 97 lb 10/1/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2004 42 Female 190 lb 10/10/2008 United States
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 10/1/2008 65 Female 192 lb 10/23/2008 United States
Primary
Concomitant
Thrombosis Other Serious 3/27/2008 68 Female 130 lb 10/9/2008 United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 10/1/2008 65 Female 192 lb 11/6/2008 United States
Primary
Concomitant
Hepatic Steatosis Other Serious 3/19/2008 50 Female 190 lb 11/14/2008 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2008 65 Female 11/24/2008 United States
Primary
Concomitant
Tooth Disorder Hospitalization 9/1/2008 65 Female 192 lb 12/16/2008 Other Health Professional United States
Primary
Concomitant
Tumour Necrosis Other Serious 4/1/2006 45 Male 161 lb 4/1/2009 United States
Primary
Concomitant
Surgical Procedure Repeated Hospitalization 6/6/2008 49 Female 110 lb 4/3/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 3/31/2009 46 Female 150 lb 4/13/2009 United States
Primary
Concomitant
Myalgia Hospitalization 3/22/2009 52 Female 4/28/2009 United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 2/1/2009 65 Female 181 lb 5/4/2009 Physician United States
Primary
Concomitant
Pituitary Tumour Other Serious 4/1/2009 51 Female 5/13/2009 United States
Primary
Concomitant
Retinal Vein Occlusion Other Serious 5/12/2009 Female 6/29/2009 Consumer United States
Primary
Secondary
Superficial Injury Of Eye Other Serious 6/12/2009 38 Female 6/24/2009 Consumer United States
Primary
Secondary
Retinal Vein Occlusion Other Serious 5/12/2009 39 Female 7/2/2009 Consumer United States
Primary
Secondary
Staphylococcal Infection Hospitalization 65 Female 176 lb 7/8/2009 Physician United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2009 57 Female 8/4/2009 Consumer Brazil
Primary
Concomitant
Spinal Fracture Other Serious 11/11/2007 43 Female 141 lb 8/10/2009 Physician United States
Primary
Concomitant
Visual Field Defect Other Serious 5/12/2009 38 Female 9/10/2009 United States
Primary
Secondary
Constipation Other Serious 12/1/2008 57 Female 9/9/2009 United States
Primary
Concomitant
Vomiting Other Serious 7/1/2009 59 Female 10/7/2009 United States
Primary
Concomitant
Nausea Other Serious 9/1/2009 31 Female 10/8/2009 United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 6/1/2008 32 Male 10/22/2009 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 7/16/2009 48 Male 11/18/2009 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 7/1/2008 46 Female 12/11/2009 Physician United States
Primary
Concomitant
Hip Arthroplasty Hospitalization 10/22/2009 Female 12/28/2009 Canada
Primary
Concomitant
Vomiting Other Serious 7/1/2009 59 Female 201 lb 2/12/2010 United States
Primary
Concomitant
Urticaria Hospitalization 10/22/2009 Female 2/11/2010 Canada
Primary
Concomitant
Paraesthesia Other Serious 1/12/2010 60 Female 150 lb 2/22/2010 Physician United States
Primary
Concomitant
Skin Exfoliation Hospitalization 1/1/2009 63 Female 240 lb 3/5/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/19/2010 45 Female 3/9/2010 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 5/3/2008 38 Female 201 lb 3/16/2010 United States
Primary
Concomitant
Progressive Multiple Sclerosis Hospitalization 1/1/2010 41 Male 185 lb 3/12/2010 United States
Primary
Concomitant
Movement Disorder Other Serious 1/1/2007 52 Female 214 lb 3/17/2010 United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2010 59 Female 132 lb 3/17/2010 Physician United States
Primary
Concomitant
Skin Reaction Hospitalization 1/1/2009 63 Female 240 lb 3/19/2010 Other Health Professional United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 12/1/2009 51 Female 231 lb 3/30/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 29 Female 320 lb 3/30/2010 United States
Primary
Concomitant
Purulence Other Serious 1/1/2005 30 Female 134 lb 3/29/2010 Physician United States
Primary
Concomitant
Nausea Other Serious 9/1/2009 31 Female 3/29/2010 Other Health Professional United States
Primary
Concomitant
Renal Disorder Hospitalization 12/1/2009 43 Female 4/12/2010 Brazil
Primary
Concomitant
Pain In Extremity Other Serious 12/1/2008 57 Female 4/21/2010 United States
Primary
Concomitant
Optic Neuritis Other Serious 1/1/2009 54 Female 280 lb 5/6/2010 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 6/1/2008 32 Male 5/10/2010 Other Health Professional United States
Primary
Concomitant
Nuclear Magnetic Resonance Imaging Abnormal Hospitalization 5/1/2010 51 Female 6/1/2010 Brazil
Primary
Concomitant
Optic Neuritis Hospitalization 4/18/2010 28 Female 401 lb 6/8/2010 United States
Primary
Concomitant
Optic Neuritis Hospitalization 4/18/2010 28 Female 401 lb 6/16/2010 United States
Primary
Concomitant
Thyroid Cancer Hospitalization 4/23/2010 34 Female 203 lb 6/23/2010 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 4/18/2010 28 Female 450 lb 6/28/2010 United States
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Other Serious 9/1/2009 61 Female 7/1/2010 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 1/1/2010 36 Female 7/8/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2009 27 Female 395 lb 7/15/2010 United States
Primary
Concomitant
Hypoaesthesia Hospitalization 4/1/2010 42 Female 146 lb 7/15/2010 United States
Primary
Concomitant
Unevaluable Event Hospitalization 6/6/2008 49 Female 110 lb 7/26/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 49 Male 7/30/2010 United States
Primary
Concomitant
Injection Site Pain Hospitalization 1/1/2010 43 Female 234 lb 7/30/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 5/9/2010 45 Male 159 lb 8/2/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 12/19/2008 39 Female 161 lb 8/5/2010 United States
Primary
Concomitant
Upper Limb Fracture Other Serious 11/11/2007 43 Female 141 lb 8/6/2010 Physician United States
Primary
Concomitant
Injection Site Erythema 1/1/2010 51 Female 9/13/2010 Consumer United States
Primary
Concomitant
Injection Site Erythema 1/1/2010 55 Female 9/21/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2010 59 Female 132 lb 9/27/2010 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2010 46 Female 218 lb 10/1/2010 Physician United States
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2008 42 Female 240 lb 10/5/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2010 48 Female 10/6/2010 Consumer United Kingdom
Primary
Concomitant
Partial Seizures Other Serious 1/1/2010 46 Female 10/18/2010 Physician United States
Primary
Secondary
Concomitant
Myopathy Toxic Hospitalization 1/1/2009 Female 10/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2007 49 Female 214 lb 12/8/2010 Consumer United States
Primary
Concomitant
Urticaria Other Serious 8/31/2010 57 Female 151 lb 11/30/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 6/1/2006 29 Female 252 lb 1/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Blood Potassium Decreased Hospitalization 2/19/2010 45 Female 1/31/2011 Physician United States
Primary
Concomitant
Contusion Other Serious 3/1/2010 56 Female 117 lb 2/1/2011 Consumer United States
Primary
Concomitant
Hypothyroidism Other Serious 1/1/2010 44 Female 2/9/2011 Physician Sweden
Primary
Concomitant
Chest Discomfort Other Serious 8/31/2010 57 Female 151 lb 2/3/2011 Physician United States
Primary
Concomitant
Arthritis 1/10/2011 60 Female 2/17/2011 Physician United States
Primary
Concomitant
Fatigue Hospitalization 1/1/2010 41 Male 185 lb 2/24/2011 Other Health Professional United States
Primary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 42 Female 3/1/2011 Consumer United States
Primary
Concomitant
Aphonia Other Serious 11/1/2010 59 Female 3/28/2011 Consumer Brazil
Primary
Concomitant
Oedema Peripheral Hospitalization 6/1/2006 29 Female 252 lb 4/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 6/1/2006 29 Female 245 lb 4/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/1/2011 41 Female 4/19/2011 Physician United States
Primary
Concomitant
Hypothyroidism Other Serious 1/1/2010 44 Female 4/29/2011 Physician Sweden
Primary
Concomitant
Alopecia Other Serious 1/1/2008 50 Female 185 lb 5/26/2011 Physician United States
Primary
Concomitant
Blood Pressure Increased Other Serious 7/1/2009 59 Female 201 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 3/24/2011 41 Female 187 lb 6/2/2011 Consumer Germany
Primary
Concomitant
Malaise Hospitalization 11/1/2009 51 Female 231 lb 6/3/2011 Physician United States
Primary
Concomitant
Uterine Cancer Other Serious Female 249 lb 6/8/2011 Pharmacist United States
Primary
Concomitant
Injection Site Erythema Other Serious 5/1/2011 55 Female 181 lb 6/14/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 6/1/2006 29 Female 245 lb 6/15/2011 Physician United States
Primary
Secondary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 2/11/2011 42 Female 6/22/2011 Other Health Professional United States
Primary
Concomitant
Headache Other Serious 11/30/2010 35 Female 6/23/2011 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 11/1/2009 51 Female 231 lb 6/24/2011 Physician United States
Primary
Concomitant
Injection Site Discolouration Other Serious Female 6/24/2011 Physician United States
Primary
Concomitant
Injection Site Haematoma Other Serious 5/1/2011 55 Female 181 lb 6/24/2011 Consumer United States
Primary
Concomitant
Staphylococcal Abscess Hospitalization 11/1/2010 45 Female 148 lb 6/30/2011 Physician United States
Primary
Concomitant
Asthenia Other Serious 5/1/2011 55 Female 185 lb 7/1/2011 Consumer United States
Primary
Concomitant
Ovarian Germ Cell Teratoma Benign Other Serious 1/1/2009 48 Female 134 lb 6/29/2011 Other Health Professional United States
Primary
Concomitant
Fibula Fracture Hospitalization 8/3/2010 45 Female 251 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 1/1/2011 60 Female 7/22/2011 Consumer Brazil
Primary
Secondary
Concomitant
Injection Site Reaction Other Serious 51 Female 172 lb 6/1/2011 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 11/7/2010 58 Female 150 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Multiple Sclerosis Life Threatening 7/17/2011 Female 7/26/2011 Physician Israel
Primary
Concomitant
Drug Ineffective Hospitalization 7/17/2011 Female 8/3/2011 Physician Israel
Primary
Concomitant
Urinary Tract Infection Other Serious 6/1/2011 47 Female 8/4/2011 Consumer Brazil
Primary
Concomitant
Anaemia Other Serious 1/1/2008 37 Female 201 lb 8/8/2011 Consumer United States
Primary
Concomitant
Headache Other Serious 11/30/2010 35 Female 8/9/2011 United States
Primary
Concomitant
Epilepsy Hospitalization 7/17/2011 Female 8/10/2011 Physician Israel
Primary
Concomitant
Chills Other Serious 1/1/2009 40 Female 110 lb 8/11/2011 Consumer Brazil
Primary
Concomitant
Malaise Other Serious 5/18/2011 52 Male 301 lb 8/18/2011 United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 5/1/2011 68 Female 143 lb 8/28/2011 Physician Germany
Primary
Concomitant
Coagulation Time Abnormal Other Serious Male 198 lb 9/2/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Death 5/1/2011 68 Female 143 lb 9/2/2011 Physician Germany
Primary
Concomitant

Drug Data