Levothyroxine Sodium combined with Pregabalin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypertensive Crisis Other Serious 10/4/2005 54 Female 159 lb 2/27/2006 Pharmacist Germany
Primary
Concomitant
Suicidal Ideation Hospitalization 1/16/2006 44 Male 182 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 60 Female 182 lb 11/22/2006 Pharmacist United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 60 Female 182 lb 1/17/2007 Pharmacist United Kingdom
Primary
Concomitant
Heart Rate Increased Other Serious 8/22/2005 67 Female 210 lb 1/12/2007 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/28/2006 Female 168 lb 6/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 5/25/2007 70 Female 7/20/2007 Consumer France
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 5/25/2007 70 Female 7/23/2007 Consumer France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/9/2006 67 Female 8/10/2007 United States
Primary
Secondary
Concomitant
Tremor Disability Female 112 lb 8/29/2007 Physician South Africa
Primary
Concomitant
Tremor Disability Female 112 lb 9/4/2007 Physician South Africa
Primary
Concomitant
Urticaria Hospitalization 9/8/2007 58 Female 198 lb 9/13/2007 Consumer United States
Primary
Concomitant
Urticaria Hospitalization 9/8/2007 58 Female 198 lb 9/25/2007 Physician United States
Primary
Concomitant
Post Procedural Complication Hospitalization 8/1/2007 58 Female 11/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Complication Hospitalization 8/30/2007 59 Female 12/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Swelling 6/1/2006 Female 241 lb 12/14/2007 Consumer United States
Primary
Concomitant
Pulmonary Necrosis Other Serious 11/1/2003 Female 126 lb 1/4/2008 Physician United States
Primary
Concomitant
Lethargy 7/4/2007 Male 43 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2007 78 Female 12/3/2007 Consumer United States
Primary
Concomitant
Swelling 6/1/2006 Female 241 lb 3/14/2008 Physician United States
Primary
Concomitant
Injection Site Pain Female 185 lb 3/15/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/24/2007 89 Female 3/11/2008 Physician France
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 50 Female 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 3/31/2008 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 50 Female 4/25/2008 United States
Primary
Secondary
Renal Failure Acute Hospitalization 50 Female 6/13/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity 4/1/2008 Female 226 lb 6/13/2008 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 50 Female 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 50 Female 6/27/2008 Physician United States
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 3/30/2008 Female 202 lb 7/2/2008 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 7/28/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Death 5/12/2008 55 Female 254 lb 8/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Alopecia 3/1/2008 Female 250 lb 9/2/2008 Consumer United States
Primary
Concomitant
Fall 7/1/2006 Female 155 lb 9/2/2008 Consumer United States
Primary
Concomitant
Rash Hospitalization 8/5/2008 Female 143 lb 9/8/2008 Physician Portugal
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 8/5/2008 Female 143 lb 9/8/2008 Physician Portugal
Primary
Secondary
Concomitant
Underdose 1/1/2007 Female 107 lb 9/12/2008 Physician United States
Primary
Concomitant
Oedema Peripheral 6/19/2008 Female 269 lb 9/12/2008 United States
Primary
Concomitant
Photosensitivity Reaction Hospitalization 7/1/2007 Female 133 lb 9/12/2008 Physician United States
Primary
Concomitant
Rash Hospitalization 8/5/2008 Female 143 lb 9/17/2008 Physician Portugal
Primary
Secondary
Concomitant
Renal Injury Hospitalization 50 Female 9/12/2008 United States
Primary
Concomitant
Rash Erythematous Hospitalization 8/5/2008 Female 143 lb 9/19/2008 Physician Portugal
Primary
Secondary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/3/2008 United States
Primary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/6/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 8/26/2008 51 Female 10/14/2008 Consumer India
Primary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 11/18/2008 Consumer United States
Primary
Concomitant
Somnolence 6/20/2008 Female 175 lb 12/4/2008 Other Health Professional United States
Primary
Concomitant
Fungal Infection 5/1/2008 Female 300 lb 12/12/2008 United States
Primary
Concomitant
Procedural Complication 8/21/2008 Male 12/12/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 10/6/2008 Female 285 lb 12/12/2008 United States
Primary
Concomitant
Onychomycosis 10/6/2008 Female 146 lb 12/12/2008 United States
Primary
Concomitant
Tenderness 1/1/2008 Female 12/12/2008 Other Health Professional United States
Primary
Concomitant
Muscle Spasms 10/13/2008 Female 12/12/2008 United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2008 59 Female 238 lb 12/10/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 50 Female 12/11/2008 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Rash Female 146 lb 2/5/2009 Consumer United States
Primary
Concomitant
Metastases To Meninges Other Serious 1/4/2009 Female 2/5/2009 Physician Canada
Primary
Concomitant
Swollen Tongue 1/28/2009 Female 2/12/2009 Consumer
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 108 lb 3/12/2009 Physician United States
Primary
Concomitant
Tremor 1/1/1998 Female 130 lb 3/12/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection 10/25/2008 Female 3/14/2009 United States
Primary
Concomitant
Sudden Unexplained Death In Epilepsy Death 3/9/2009 Female 3/23/2009 Germany
Primary
Concomitant
Peripheral Ischaemia Other Serious 2/20/2009 53 Female 4/15/2009 Pharmacist France
Primary
Concomitant
Oxygen Saturation Decreased Required Intervention 3/25/2009 57 Female 3/27/2009 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 6/5/2009 Physician United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Hospitalization 60 Male 6/15/2009 United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Required Intervention 3/25/2009 57 Female 170 lb 5/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 2/25/2009 78 Male 7/22/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Somnolence Other Serious 5/28/2005 Female 8/17/2009 Consumer Japan
Primary
Secondary
Concomitant
Hyperhidrosis 10/15/2008 Female 8/22/2009 United States
Primary
Concomitant
Pruritus 10/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Urine Ketone Body Present Other Serious 7/25/2009 Female 9/4/2009 Physician United States
Primary
Concomitant
Lupus-like Syndrome Other Serious 1/1/2009 Female 290 lb 9/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 54 Female 168 lb 9/23/2009 Consumer United States
Primary
Secondary
Concomitant
Sensory Loss Other Serious 2/11/2009 Female 232 lb 9/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2009 29 Male 307 lb 10/20/2009 Physician United States
Primary
Concomitant
Walking Aid User Hospitalization 7/1/2007 64 Female 124 lb 11/9/2009 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Dyspnoea 1/1/2009 Female 290 lb 12/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 12/7/2009 Physician United States
Primary
Secondary
Concomitant
Wound Infection Pseudomonas Hospitalization 11/24/2009 49 Female 12/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Exfoliation Life Threatening 11/24/2009 Female 1/4/2010 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2008 47 Female 1/11/2010 Physician United States
Primary
Secondary
Poisoning Death 47 Female 1/17/2010 Physician United States
Primary
Secondary
Laryngeal Cancer Other Serious 11/25/2009 74 Female 1/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Injection Site Swelling 10/1/2008 Female 1/30/2009 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 11/13/2009 Female 126 lb 1/29/2010 Physician United Kingdom
Primary
Concomitant
Completed Suicide Death 47 Female 1/27/2010 Other Health Professional United States
Primary
Secondary
Poisoning Death 47 Female 1/26/2010 Physician United States
Primary
Secondary
Poisoning Death 47 Female 1/26/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 47 Female 2/2/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 47 Female 2/1/2010 Physician United States
Primary
Secondary
Completed Suicide Death 47 2/22/2010 United States
Primary
Secondary
Completed Suicide Death 47 Female 2/24/2010 Physician United States
Primary
Secondary
Vomiting Other Serious 9/1/2007 61 Male 3/17/2010 Lawyer United States
Primary
Concomitant
Poisoning Death 47 Female 3/9/2010 Physician United States
Primary
Secondary
Unevaluable Event Other Serious 2/12/2010 32 Female 3/8/2010 Physician United States
Primary
Concomitant
Death Death 1/1/2008 47 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Aggression Other Serious 9/1/2009 63 Male 3/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aggression Other Serious 9/1/2009 63 Male 3/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 11/27/2007 62 Female 3/25/2010 Other Health Professional United States
Primary
Concomitant
Aggression Other Serious 9/1/2009 63 Male 3/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aggression Other Serious 9/1/2009 63 Male 4/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/13/2010 65 Female 5/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/13/2010 65 Female 6/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/13/2010 65 Female 6/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/13/2010 65 Female 6/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 9/1/2007 61 Male 165 lb 6/17/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 3/1/2008 82 Male 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 80 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 3/14/2010 66 Female 176 lb 6/24/2010 Physician Greece
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2009 45 Female 8/12/2010 Other Health Professional France
Primary
Secondary
Concussion Hospitalization 8/20/2010 62 Female 191 lb 9/3/2010 Physician Sweden
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 2/25/2009 78 Male 9/10/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 3/1/2008 82 Male 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 9/1/2007 61 Male 165 lb 9/22/2010 Lawyer United States
Primary
Concomitant
Bronchopneumonia Death Female 10/8/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Death Female 10/19/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Death Female 10/21/2010 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2010 38 Male 10/26/2010 Consumer United States
Primary
Concomitant
Pneumonia Death Female 11/10/2010 Physician United Kingdom
Primary
Concomitant
Subdural Haemorrhage Hospitalization 9/13/2010 40 Female 11/22/2010 Other Health Professional Czech Republic
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 9/1/2010 60 Female 11/22/2010 Other Health Professional France
Primary
Concomitant
Subdural Haemorrhage Hospitalization 9/13/2010 40 Female 12/3/2010 Other Health Professional Czech Republic
Primary
Concomitant
Tremor 10/1/2009 12/14/2010 Consumer United States
Primary
Concomitant
Sinusitis 1/1/2009 12/15/2010 Consumer United States
Primary
Concomitant
Injection Site Swelling 12/17/2010 Consumer United States
Primary
Concomitant
Erythema 8/15/2010 12/23/2010 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 12/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2010 70 Female 198 lb 12/10/2010 United States
Primary
Secondary
Concomitant
Sudden Death Death 61 Female 319 lb 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acne Disability 1/1/2010 69 Male 2/21/2011 Consumer Germany
Primary
Concomitant
Depressed Level Of Consciousness Life Threatening 1/19/2011 83 Female 2/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 1/19/2011 83 Female 2/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Depressed Level Of Consciousness Life Threatening 1/19/2011 83 Female 3/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Life Threatening 1/19/2011 83 Female 3/1/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/7/2008 26 Female 3/17/2011 Physician France
Primary
Concomitant
Psoriasis Disability 8/1/2010 69 Male 304 lb 3/18/2011 Physician Germany
Primary
Concomitant
Blood Amylase Increased Hospitalization 9/8/2010 58 Female 3/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Blood Potassium Decreased Hospitalization 12/1/2010 52 Male 3/28/2011 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/5/2010 50 Female 206 lb 3/29/2011 Physician United States
Primary
Concomitant
Death Death 2/23/2011 82 Male 3/31/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Concussion Hospitalization 8/20/2010 62 Female 191 lb 5/5/2011 Physician Sweden
Primary
Secondary
Concomitant
Death Death 56 Female 101 lb 5/13/2011 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data