Levothyroxine Sodium combined with Paclitaxel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dizziness 9/1/2005 80 Male 170 lb 12/7/2005 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 9/15/2005 81 Female 2/23/2006 Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 3/28/2006 Female 192 lb 4/17/2006 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 3/8/2006 77 Female 170 lb 4/17/2006 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/8/2006 77 Female 5/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 77 Female 170 lb 5/17/2006 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 2/15/2006 77 Female 177 lb 7/20/2006 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/8/2006 77 Female 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/15/2006 66 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 9/10/2006 66 Male 132 lb 2/28/2007 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 9/10/2006 66 Male 132 lb 3/7/2007 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/17/2007 70 Female 159 lb 3/19/2007 Consumer United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/17/2007 70 Female 159 lb 4/5/2007 Consumer United States
Primary
Secondary
Concomitant
Nervous System Disorder Disability 12/22/2005 46 Female 282 lb 4/30/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/27/2007 81 Male 5/11/2007 France
Primary
Concomitant
Sepsis Hospitalization 4/15/2007 76 Female 146 lb 7/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 7/13/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/15/2005 81 Female 7/14/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 7/25/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 8/7/2007 Physician United States
Primary
Concomitant
Dehydration Hospitalization 7/14/2007 72 Female 187 lb 8/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 71 Male 9/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/14/2007 72 Female 174 lb 10/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/14/2007 72 Female 174 lb 10/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 71 Male 10/23/2007 Other Health Professional United States
Primary
Concomitant
Hypogonadism Other Serious 71 Male 11/14/2007
Primary
Secondary
Concomitant
Anaemia Hospitalization 11/2/2007 Female 157 lb 11/15/2007 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 2/15/2006 77 Female 12/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Neuropathy Peripheral Male 225 lb 1/10/2008 Consumer United States
Primary
Secondary
Concomitant
Ileal Perforation Life Threatening 12/6/2007 60 Female 1/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Required Intervention 10/23/2007 54 Female 176 lb 1/10/2008 Pharmacist United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 2/8/2008 Physician United States
Primary
Concomitant
Sense Of Oppression Hospitalization 1/14/2008 65 Female 2/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 1/3/2008 70 Female 3/5/2008 Consumer United States
Primary
Concomitant
Oral Intake Reduced Male 324 lb 3/5/2008 Physician United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 3/31/2008 Consumer United States
Primary
Concomitant
Anaemia Hospitalization 11/2/2007 Female 157 lb 4/9/2008 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 5/2/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 1/14/2008 65 Female 5/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/15/2007 76 Female 146 lb 5/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Pleural Effusion Hospitalization 5/13/2008 Female 165 lb 5/23/2008 Physician Australia
Primary
Secondary
Concomitant
Intestinal Prolapse Hospitalization 6/23/2008 Female 140 lb 7/9/2008 Other Health Professional United States
Primary
Concomitant
Infection Hospitalization 7/2/2008 Female 171 lb 7/10/2008 United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Female 212 lb 7/25/2008 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 71 Male 7/30/2008 Other Health Professional United States
Primary
Secondary
Catheter Related Complication Hospitalization 5/20/2008 Female 8/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/23/2008 Female 140 lb 8/8/2008 Other Health Professional United States
Primary
Concomitant
Catheter Related Complication Hospitalization 5/20/2008 Female 8/19/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Bronchopleural Fistula Hospitalization 5/13/2008 Female 165 lb 8/29/2008 Physician Australia
Primary
Secondary
Concomitant
Wound Infection Life Threatening 8/2/2008 57 Male 175 lb 9/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Portal Vein Thrombosis Other Serious 9/9/2008 Female 10/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 6/20/2008 63 Female 128 lb 10/17/2008 Physician Germany
Primary
Secondary
Concomitant
Tonsillitis Hospitalization 6/20/2008 63 Female 128 lb 10/27/2008 Physician Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/13/2008 53 Male 170 lb 10/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/8/2007 85 Male 176 lb 11/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Other Serious 12/8/2007 Male 176 lb 11/17/2008 Other Health Professional
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 11/18/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 8/17/2008 Female 11/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 8/19/2008 Male 12/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 5/20/2008 Female 12/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 12/8/2007 Male 176 lb 12/10/2008 Other Health Professional
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 5/27/2008 Female 12/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/8/2007 85 Male 176 lb 12/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 11/29/2008 55 Female 158 lb 12/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 8/19/2008 Female 12/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 8/19/2008 Female 12/18/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 11/29/2008 55 Female 158 lb 12/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral 71 Male 225 lb 1/14/2009 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/17/2008 Female 2/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 10/30/2008 52 Female 203 lb 4/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 2/15/2006 77 Female 4/21/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 4/27/2009 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2/15/2006 78 Female 170 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 58 Female 5/28/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/11/2009 Female 171 lb 9/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/11/2009 Female 171 lb 9/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/11/2009 Female 171 lb 10/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Perforation Hospitalization 4/30/2009 79 Female 105 lb 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Skin Necrosis Hospitalization 5/20/2008 Female 11/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Nervous System Disorder Disability 12/22/2005 46 Female 282 lb 11/26/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/11/2009 Female 171 lb 11/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Cord Infarction Life Threatening 4/30/2008 Female 140 lb 12/12/2009 Consumer United States
Primary
Secondary
Concomitant
Throat Tightness Life Threatening 11/20/2009 50 Female 146 lb 1/5/2010
Primary
Concomitant
General Physical Health Deterioration Hospitalization 12/15/2009 Female 163 lb 1/14/2010 Physician Germany
Primary
Secondary
Concomitant
Spinal Cord Infarction Other Serious 70 Female 1/18/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Spinal Cord Infarction Disability 70 Female 1/19/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 6/22/2009 55 Female 155 lb 1/22/2010 Physician United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 6/22/2009 55 Female 155 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/15/2009 Female 163 lb 2/4/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/28/2010 70 Female 5/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/13/2010 65 Female 5/26/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/14/2009 80 Female 5/25/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/13/2010 65 Female 6/1/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Nervous System Disorder Disability 12/22/2005 46 Female 282 lb 6/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/13/2010 65 Female 6/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 6/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 4/13/2010 65 Female 6/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Chest Pain Hospitalization 6/21/2010 71 Female 7/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Klebsiella Test Positive Hospitalization 7/7/2010 82 Female 7/31/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/23/2010 69 Female 163 lb 8/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 9/4/2010 50 Female 117 lb 9/13/2010 Physician India
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 6/24/2008 75 Female 9/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 2/1/2010 64 172 lb 10/28/2010 Physician Germany
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 77 Female 11/11/2010 United States
Primary
Concomitant
Dental Caries Other Serious 2/4/2010 64 Female 172 lb 12/17/2010 Physician Germany
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 12/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/21/2010 36 Female 183 lb 1/11/2011 Physician United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 2/1/2010 64 Female 172 lb 2/3/2011 Physician Germany
Primary
Secondary
Concomitant
Arterial Thrombosis Limb Hospitalization 1/5/2011 66 Female 132 lb 2/25/2011 Pharmacist Portugal
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 77 Female 3/7/2011 Other Health Professional United States
Primary
Concomitant
Acute Febrile Neutrophilic Dermatosis Other Serious 77 Female 3/7/2011 Other Health Professional United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 77 Female 3/11/2011 Physician United States
Primary
Concomitant
Hypertensive Crisis Other Serious 11/25/2010 59 Female 4/8/2011 Consumer United States
Primary
Secondary
Concomitant
Tooth Abscess Hospitalization 3/8/2011 Female 163 lb 4/18/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 5/9/2011 46 Female 202 lb 6/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 5/9/2011 46 Female 202 lb 6/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Foot Fracture Other Serious 2/21/2011 42 Female 181 lb 6/20/2011 Physician Germany
Primary
Concomitant
Nephritic Syndrome Hospitalization 11/10/2009 37 Female 122 lb 6/20/2011 Physician Brazil
Primary
Secondary
Concomitant
Hypoxia Hospitalization 7/5/2011 59 Female 192 lb 7/12/2011 Consumer United States
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 7/5/2011 59 Female 192 lb 7/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 5/25/2011 83 Female 117 lb 7/18/2011 Consumer United States
Primary
Concomitant
Tooth Abscess Hospitalization 3/8/2011 Female 163 lb 7/19/2011 Physician United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 5/30/2011 60 Female 236 lb 7/6/2011 Other Health Professional
Primary
Secondary
Concomitant
Lymphopenia Other Serious 6/13/2011 73 Female 117 lb 7/29/2011 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 2/21/2011 42 Female 181 lb 8/2/2011 Physician Germany
Primary
Concomitant
Shock Life Threatening 5/5/2011 71 Female 8/9/2011 Other Health Professional France
Primary
Concomitant
Transient Ischaemic Attack Other Serious 5/25/2011 83 Female 117 lb 8/26/2011 Consumer United States
Primary
Concomitant
Shock Life Threatening 5/5/2011 71 Female 9/7/2011 Other Health Professional France
Primary
Concomitant
Blood Urea Increased Hospitalization 3/22/2011 66 Female 238 lb 9/15/2011 United States
Primary
Secondary
Concomitant
Infusion Related Reaction Life Threatening 5/5/2011 71 Female 9/15/2011 Other Health Professional France
Primary
Concomitant
Infection Hospitalization 5/11/2011 72 Female 123 lb 9/23/2011 Physician United States
Primary
Secondary
Concomitant
Loose Tooth Other Serious 9/14/2011 57 Female 10/12/2011 Physician Hungary
Primary
Secondary
Concomitant
Eosinophilia 6/30/2011 78 Female 141 lb 10/16/2011 Physician Germany
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 1/1/2001 62 Male 10/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 9/14/2011 57 Female 10/20/2011 Physician Hungary
Primary
Secondary
Concomitant
Neutrophil Count Other Serious 5/11/2011 72 Female 123 lb 11/1/2011 Physician United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 11/15/2011 55 Female 11/21/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 50 Female 11/30/2011 Physician France
Primary
Concomitant
Haemoglobin Decreased Hospitalization 5/30/2011 60 Female 236 lb 11/29/2011 Other Health Professional
Primary
Secondary
Concomitant
Tachycardia Death 11/28/2011 Other Health Professional France
Primary
Secondary
Concomitant
Dehydration Hospitalization 12/8/2007 85 Male 176 lb 12/14/2011 Consumer United States
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 50 Female 1/24/2012 Physician France
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 50 Female 1/24/2012 Physician France
Primary
Secondary
Concomitant
Left Ventricular Failure Death 11/25/2011 74 Female 185 lb 1/27/2012 Physician Germany
Primary
Secondary
Concomitant
Exposed Bone In Jaw Other Serious 9/14/2011 57 Female 2/6/2012 Physician Hungary
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 1/25/2012 52 Female 2/13/2012 Other Health Professional Italy
Primary
Concomitant
Septic Shock Hospitalization 1/25/2010 51 Female 2/20/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data