Levothyroxine Sodium combined with Nitroglycerin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 11/24/2005 73 Female 165 lb 1/2/2006 Physician France
Primary
Concomitant
Ischaemic Stroke Hospitalization 1/1/2002 75 Female 181 lb 1/23/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2006 83 Female 190 lb 1/30/2006 Other Health Professional Canada
Primary
Concomitant
Hypertension Hospitalization 1/10/2006 58 Male 1/30/2006 Physician United States
Primary
Concomitant
Haematuria Life Threatening 11/16/2005 88 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Epistaxis 12/12/2005 69 Male 177 lb 12/16/2005 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Other Serious 5/15/2003 76 Female 77 lb 2/21/2006 Lawyer United Kingdom
Primary
Concomitant
Wrong Technique In Drug Usage Process Required Intervention 10/8/2005 86 Female 89 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 9/1/2005 Female 3/1/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Cerebral Infarction Hospitalization 3/19/2004 72 Female 4/28/2006 Norway
Primary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2006 83 Female 190 lb 5/10/2006 Other Health Professional Canada
Primary
Concomitant
Heart Rate Decreased Required Intervention 3/19/2006 78 Male 185 lb 4/16/2006 Pharmacist United States
Primary
Concomitant
Pruritus Other Serious 11/1/2005 60 Female 207 lb 5/26/2006 Physician Slovenia
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/26/2006 61 Male 7/6/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/4/2006 80 Male 163 lb 5/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 5/12/2006 84 Male Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 130 lb 8/11/2006 Physician United States
Primary
Concomitant
Tooth Fracture Other Serious Female 185 lb 8/14/2006 United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2006 83 Female 180 lb 7/19/2006 United States
Primary
Concomitant
Ischaemic Stroke Life Threatening 5/29/2006 86 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 8/10/2006 53 Female 220 lb 8/31/2006 United States
Primary
Concomitant
Interacting
Ventricular Fibrillation Death 8/10/2006 53 Female 220 lb 9/11/2006 Pharmacist United States
Primary
Concomitant
Interacting
Ventricular Fibrillation Death 8/4/2006 53 Female 220 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Interacting
Pain In Extremity Life Threatening 7/30/2006 79 Female 110 lb 10/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Life Threatening 7/30/2006 79 Female 110 lb 10/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Hospitalization 7/12/2006 85 Female 135 lb 8/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 10/13/2006 80 Female 141 lb 11/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Haemorrhage Other Serious 11/10/2006 86 Female 11/17/2006 Consumer United States
Primary
Concomitant
Liver Disorder Other Serious 11/14/2006 66 Male 190 lb 11/29/2006 Other Health Professional Canada
Primary
Concomitant
Lichenoid Keratosis Hospitalization 12/15/2005 60 Female 12/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vaccination Complication Other Serious 11/14/2006 66 Male 190 lb 12/1/2006 Other Health Professional Canada
Primary
Concomitant
Pollakiuria Hospitalization 10/13/2006 80 Female 12/8/2006 Physician France
Primary
Secondary
Concomitant
Vaccination Complication Hospitalization 11/14/2006 66 Male 190 lb 12/14/2006 Other Health Professional Canada
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 9/6/2006 69 Female 12/14/2006 Other Health Professional France
Primary
Concomitant
Vaginal Haemorrhage 11/10/2006 86 Female 12/18/2006 Consumer United States
Primary
Concomitant
Haemorrhoidal Haemorrhage 11/10/2006 86 Female 12/18/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/12/2006 65 Male 196 lb 12/22/2006 Physician France
Primary
Concomitant
Hypoglycaemia Death 79 Male 231 lb 1/10/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Haemorrhage Intracranial Other Serious 6/2/2006 Male 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/16/2006 Male 158 lb 1/19/2007 Canada
Primary
Concomitant
Pallor Other Serious 1/7/2007 Male 1/22/2007 Pharmacist United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 196 lb 2/6/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 2/26/2003 Male 230 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Interacting
Hypoglycaemia Death 79 Male 231 lb 2/6/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 196 lb 2/13/2007 Physician United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 3/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli 70 Male 3/2/2007 Pharmacist United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 10/13/2006 80 Female 141 lb 3/7/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 10/13/2006 80 Female 141 lb 3/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Protein Urine Required Intervention 70 Male 2/23/2006 United States
Primary
Concomitant
Psychomotor Hyperactivity Hospitalization 1/17/2007 81 Male 3/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Protein Urine Required Intervention 7/21/2005 70 Male 189 lb 6/2/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/15/2007 77 Female 190 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Psychomotor Hyperactivity Hospitalization 1/17/2007 81 Male 194 lb 4/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Hospitalization 68 Female 4/13/2007 Consumer United States
Primary
Concomitant
Rash Hospitalization 9/1/2006 Female 186 lb 5/1/2007 Physician United States
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 4/16/2007 67 Male 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 11/1/2006 68 Female 5/29/2007 Physician United States
Primary
Concomitant
Lichenoid Keratosis Hospitalization 12/15/2005 60 Female 6/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Dizziness Life Threatening 7/1/2006 82 Male 208 lb 6/7/2007 Pharmacist United States
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2007 Male 184 lb 6/13/2007 Consumer United States
Primary
Concomitant
Lichenoid Keratosis Hospitalization 12/15/2005 60 Female 6/29/2007 Other Health Professional France
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 6/1/2007 64 Male 164 lb 7/20/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased 8/1/2006 Female 7/26/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 1/7/2007 39 Male 224 lb 9/7/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 1/1/2006 Female 9/21/2007 Consumer Canada
Primary
Concomitant
Haemorrhage Hospitalization 7/18/2007 60 Male 9/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Other Serious 1/7/2007 39 Male 224 lb 9/24/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/19/1999 89 Female 10/10/2007 France
Primary
Concomitant
Pancytopenia Other Serious 80 Female 10/18/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 62 Male 10/25/2007
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 9/30/2007 83 Female 10/26/2007 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 8/31/2007 75 Female 168 lb 11/5/2007 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased 85 Female 11/13/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 9/30/2007 83 Female 11/21/2007 Physician United States
Primary
Concomitant
Tenosynovitis Other Serious 62 Male 11/28/2007 Pharmacist Canada
Primary
Concomitant
Somnolence 8/25/1997 77 Male 201 lb 1/4/2008 Pharmacist Canada
Primary
Concomitant
Stomatitis Other Serious 9/1/2003 Female 194 lb 1/25/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 2/1/2008 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Other Serious 1/1/2008 Female 142 lb 2/15/2008 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 Female 2/28/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/12/2007 83 Male 12/20/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Female 2/27/2008 Physician Canada
Primary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 3/5/2008 Consumer Canada
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 9/4/2007 Female 3/17/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Malaise Hospitalization 6/1/2007 65 Male 164 lb 3/14/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 3/19/2008 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious Female 198 lb 3/28/2008 United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 9/3/2007 4/4/2008 Consumer Canada
Primary
Secondary
Concomitant
Extrasystoles Other Serious 3/23/2008 Female 268 lb 4/7/2008 Consumer United States
Primary
Concomitant
Tracheal Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 4/3/2008 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 2/1/2008 77 Male 4/8/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 4/7/2008 Physician United States
Primary
Concomitant
Pathological Gambling Hospitalization 1/1/2002 Male 218 lb 5/27/2008 Consumer United States
Primary
Concomitant
Extrasystoles Other Serious 3/23/2008 Female 268 lb 5/28/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 2/1/2008 77 Male 5/29/2008 Pharmacist United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 2/20/2008 65 Female 180 lb 5/23/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 5/7/2008 79 Female 5/23/2008 United States
Primary
Concomitant
Drug Effect Decreased Hospitalization 8/5/2007 88 Female 5/7/2008 Physician United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 9/3/2007 6/12/2008 Consumer Canada
Primary
Secondary
Concomitant
Palpitations 10/1/2007 83 Female 4/10/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Other Serious 6/10/2008 63 Female 229 lb 6/13/2008 Consumer United States
Primary
Concomitant
Nightmare Other Serious 5/1/2008 72 Female 123 lb 6/16/2008 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Swollen Tongue Life Threatening 3/30/2008 Female 202 lb 7/2/2008 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 2/20/2008 65 Female 180 lb 7/2/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 2/20/2008 65 Female 180 lb 7/2/2008 United States
Primary
Concomitant
Myalgia Other Serious 6/1/2008 7/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious Female 131 lb 7/11/2008 United States
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 8/26/1999 Female 7/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Disorder 2/22/2007 Female 148 lb 7/25/2008 Consumer United States
Primary
Concomitant
Status Epilepticus Hospitalization 11/2/2007 Male 8/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/26/1999 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Panic Attack Other Serious 1/1/2008 Female 250 lb 8/11/2008 Consumer United States
Primary
Concomitant
Spinal Fusion Surgery Other Serious 1/1/2006 152 lb 8/11/2008 Other Health Professional United States
Primary
Concomitant
Palpitations 10/1/2007 83 Female 7/7/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Death 5/12/2008 55 Female 254 lb 8/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 7/25/2008 74 Female 8/18/2008 Physician United States
Primary
Concomitant
Chromaturia 7/31/2008 Female 8/21/2008 Consumer United States
Primary
Concomitant
Rash Macular 7/11/2008 Female 8/29/2008 United States
Primary
Concomitant
Drug Interaction Other Serious 8/5/2008 91 Female 132 lb 9/2/2008 Other Health Professional Portugal
Primary
Concomitant
Interacting
No Adverse Event Female 131 lb 9/2/2008 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 7/21/2008 79 Female 9/10/2008 Pharmacist United States
Primary
Concomitant
Drug Interaction Other Serious 8/5/2008 91 Female 132 lb 9/23/2008 Other Health Professional Portugal
Primary
Concomitant
Interacting
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/25/2008
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Wrist Fracture Other Serious 1/27/2008 72 Female 10/2/2008 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/5/2008 Female 10/2/2008 Other Health Professional France
Primary
Concomitant
Interacting
Tremor Hospitalization 7/1/2008 Female 130 lb 10/3/2008 United States
Primary
Concomitant
Tremor Other Serious 10/6/2006 92 Female 154 lb 9/29/2008 United States
Primary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/6/2008 United States
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 10/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 8/13/2008 78 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sciatica Other Serious 8/7/2007 74 Female 198 lb 10/10/2008 Physician Australia
Primary
Concomitant
Dermatitis Other Serious 5/15/2008 79 Male 10/27/2008 Other Health Professional Italy
Primary
Concomitant
Rash Generalised Other Serious 3/13/2006 82 Female 10/22/2008 United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 6/1/2008 69 Female 121 lb 11/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 2/11/2006 66 Female 10/29/2008 Lawyer United States
Primary
Concomitant
Myalgia Other Serious 6/1/2008 69 Female 121 lb 11/11/2008 Consumer United Kingdom
Primary
Concomitant
Tinnitus Hospitalization Male 200 lb 11/10/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting 8/19/2008 74 Female 10/20/2008 United States
Primary
Concomitant

Drug Data