Levothyroxine Sodium combined with Nicorandil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vertigo Hospitalization 11/16/2002 Male 1/4/2006 France
Primary
Concomitant
Obsessive Thoughts Hospitalization 11/15/2005 77 Male 3/6/2006 Other Health Professional France
Primary
Secondary
Concomitant
Fall Other Serious 2/1/2006 92 Male 4/26/2006 Physician Japan
Primary
Secondary
Concomitant
Fall Other Serious 2/1/2006 92 Male 5/23/2006 Japan
Primary
Secondary
Concomitant
Peptic Ulcer Hospitalization 4/1/2006 74 Female 6/14/2006 Physician
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 6/23/2006 76 Male 165 lb 10/3/2006 Physician Austria
Primary
Concomitant
Troponin Increased Hospitalization 1/2/2006 75 Male 161 lb 10/4/2006 Physician France
Primary
Concomitant
Tachycardia Other Serious 6/23/2006 76 Male 165 lb 11/2/2006 Physician Austria
Primary
Concomitant
Tachycardia Other Serious 6/23/2006 76 Male 165 lb 11/13/2006 Physician Austria
Primary
Concomitant
Hormone Level Abnormal Hospitalization 3/22/2005 Female 137 lb 12/14/2006 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious Female 132 lb 2/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 1/1/2003 Female 3/2/2007 Pharmacist United Kingdom
Primary
Concomitant
Rhabdomyolysis Death 12/1/2006 91 Male 3/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/1/2007 United Kingdom
Primary
Concomitant
Nausea Other Serious 1/1/2003 Female 3/9/2007 Pharmacist United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 91 Male 4/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 4/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 3/1/2006 Female 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 8/31/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/6/2007 Consumer United Kingdom
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Haemorrhage Hospitalization 7/18/2007 60 Male 9/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pyuria Death 2/10/2006 Male 10/4/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 10/10/2007 Other Health Professional Australia
Primary
Concomitant
Fall Hospitalization 7/18/2007 76 Female 238 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious Female 165 lb 11/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pyuria Death 2/10/2006 Male 11/7/2007 Other Health Professional Japan
Primary
Concomitant
Head Injury Hospitalization 6/17/2007 Female 120 lb 11/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/15/2007 55 Female 287 lb 1/15/2008 Consumer United Kingdom
Primary
Concomitant
Malaise Hospitalization 5/21/2007 Female 1/16/2008 Other Health Professional France
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 1/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Death 12/1/2006 91 Male 1/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 1/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 2/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 2/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 2/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/23/2008 47 Female 256 lb 2/19/2008 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 2/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 2/11/2008 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/23/2008 47 Female 256 lb 2/22/2008 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 3/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 3/6/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 3/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/1/2006 91 Male 3/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 77 Female 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization Female 4/30/2008 United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious 4/1/2008 62 Female 229 lb 5/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sciatica Other Serious 8/7/2007 74 Female 198 lb 10/10/2008 Physician Australia
Primary
Concomitant
Rash Generalised Other Serious 3/13/2006 82 Female 10/22/2008 United Kingdom
Primary
Secondary
Concomitant
Palpitations Hospitalization 10/1/2008 80 Female 11/7/2008 Physician France
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 165 lb 11/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Other Serious 12/11/2008 Female 278 lb 1/20/2009 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/20/2009 72 Female 2/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 77 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 2/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 3/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Palpitations Hospitalization 10/1/2008 80 Female 3/20/2009 Physician France
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 77 Female 3/20/2009 Austria
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 3/23/2009 United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 77 Female 174 lb 3/26/2009 Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 77 Female 174 lb 3/26/2009 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 4/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 77 Female 4/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 1/29/2009 77 Male 5/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 5/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2008 80 Female 5/12/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vertigo Hospitalization 10/1/2008 80 Female 5/15/2009 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 5/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 77 Female 5/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 6/17/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 12/23/2008 Female 174 lb 7/28/2009 Physician Austria
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 12/23/2008 Female 174 lb 8/4/2009 Physician Austria
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 12/23/2008 Female 174 lb 8/7/2009 Physician Austria
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 1/1/2009 80 Female 8/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/19/2009 Female 143 lb 8/26/2009 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 10/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 77 Female 10/8/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 77 Female 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Off Label Use Life Threatening 9/30/2009 80 Female 11/2/2009 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/25/2006 91 Male 11/10/2009 United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 7/3/2004 Male 187 lb 11/19/2009 Physician France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 77 Female 12/10/2009 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 77 Female 12/10/2009 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 77 Female 12/14/2009 United States
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 2/25/2010 Physician United Kingdom
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 3/2/2010 Physician United Kingdom
Primary
Concomitant
Stress Other Serious 4/27/2010 83 Female 108 lb 6/4/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 6/19/2009 88 Female 143 lb 7/16/2010 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Death 10/22/2009 88 Female 2/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Death 88 Female 2/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Pressure Decreased Death 88 Female 2/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Asthenia Death 88 Female 2/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Coagulation Time Prolonged Other Serious 11/25/2010 74 Female 2/22/2011 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 11/25/2010 74 Female 3/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Coagulation Time Prolonged Other Serious 11/25/2010 74 Female 2/25/2011 Other Health Professional Denmark
Primary
Concomitant
Rhabdomyolysis Other Serious 77 Female 3/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 3/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 77 Female 4/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Interaction Other Serious 77 Female 4/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Blood Alkaline Phosphatase Increased Other Serious 77 Female 3/29/2011 Other Health Professional
Primary
Secondary
Concomitant
Cough Hospitalization 7/1/2010 75 Female 176 lb 4/27/2011 Physician United Kingdom
Primary
Concomitant
Cough Hospitalization 7/28/2009 75 Female 176 lb 5/20/2011 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 88 Male 6/15/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Deafness Unilateral Disability 8/2/2011 73 Male 9/16/2011 Other Health Professional United Kingdom
Primary
Concomitant
Deafness Unilateral Disability 8/2/2011 73 Male 9/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 9/2/2011 79 Male 9/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/28/2010 67 Female 121 lb 10/6/2011 Physician United States
Primary
Concomitant
Interacting
Hyperkalaemia Hospitalization 9/2/2011 79 Male 10/26/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cutaneous Vasculitis Other Serious 11/4/2011 85 Female 126 lb 2/5/2012 Other Health Professional United Kingdom
Primary
Concomitant
Cutaneous Vasculitis Other Serious 11/4/2011 85 Female 126 lb 2/6/2012 Physician United Kingdom
Primary
Concomitant
Vasculitis Disability 11/4/2011 85 Female 126 lb 2/7/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Skin Ulcer Disability 11/4/2011 85 Female 2/8/2012 Other Health Professional Denmark
Primary
Concomitant
Chromaturia Hospitalization 77 Female 3/1/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Blood Creatine Phosphokinase Increased Disability 77 Female 3/1/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pain In Extremity Other Serious 12/24/2011 65 Male 190 lb 3/14/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 12/24/2011 65 Male 190 lb 3/26/2012 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 65 Male 190 lb 3/22/2012 Consumer United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 12/24/2011 65 Male 190 lb 3/27/2012 Other Health Professional United Kingdom
Primary
Concomitant
Chromaturia Other Serious 77 Female 4/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Swelling Face Other Serious 3/29/2012 72 Female 155 lb 5/25/2012 Other Health Professional United Kingdom
Primary
Concomitant
Tendon Pain Hospitalization 3/15/2012 67 Female 5/30/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 3/29/2012 72 Female 5/25/2012 Other Health Professional Denmark
Primary
Concomitant
Swelling Face Other Serious 3/29/2012 72 Female 5/31/2012 Other Health Professional Denmark
Primary
Concomitant
Pneumonia Hospitalization 2/5/2012 94 Female 6/18/2012 Other Health Professional United Kingdom
Primary
Concomitant
Myalgia Other Serious 8/1/2012 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Insomnia Hospitalization 4/28/2012 48 Male 8/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 12/24/2011 65 Male 8/8/2012 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/5/2012 8/14/2012 Pharmacist United Kingdom
Primary
Concomitant
Lethargy Hospitalization 7/5/2012 65 Female 8/21/2012 Pharmacist United Kingdom
Primary
Concomitant
Muscle Twitching Hospitalization 4/28/2012 48 Male 8/1/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 7/5/2012 65 Female 8/21/2012 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data