Levothyroxine Sodium combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Heart Rate Irregular 2/1/2006 56 Male 4/25/2006 United States
Primary
Concomitant
Metastasis Other Serious 2/1/2006 56 Male 5/11/2006 United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 5/24/2006 72 Male 6/29/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2006 56 Male 190 lb 7/19/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2006 57 Male 190 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/25/2006 52 Female 141 lb 9/14/2006 France
Primary
Concomitant
Stomatitis Other Serious 7/25/2006 52 Female 141 lb 9/19/2006 France
Primary
Concomitant
Myocardial Infarction Death 10/1/2006 79 Female 10/31/2006 United States
Primary
Concomitant
Stomatitis Other Serious 7/25/2006 52 Female 141 lb 11/21/2006 France
Primary
Concomitant
Stomatitis Other Serious 7/25/2006 52 Female 141 lb 11/28/2006 France
Primary
Concomitant
Myocardial Infarction Death 10/1/2006 79 Female 1/3/2007 United States
Primary
Concomitant
Stomatitis Other Serious 7/25/2006 52 Female 141 lb 2/7/2007 France
Primary
Concomitant
Urinary Tract Infection Other Serious 11/1/2006 52 Male 320 lb 1/23/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/29/2007 46 Female 6/6/2007 Pharmacist United States
Primary
Concomitant
Psoriasis Other Serious 3/1/2007 47 Female 148 lb 9/11/2007 Other Health Professional Switzerland
Primary
Concomitant
Vomiting Other Serious 7/1/2007 70 Male 10/8/2007 United States
Primary
Concomitant
Rash Erythematous Other Serious 1/1/2007 78 Female 179 lb 11/13/2007 Consumer United States
Primary
Concomitant
Swollen Tongue Other Serious 12/10/2007 80 Male 137 lb 1/9/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vulval Disorder Other Serious 12/10/2007 80 Male 137 lb 1/15/2008 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Fatigue 10/15/2007 86 Male 137 lb 10/22/2007 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 9/1/2007 76 Female 2/12/2008 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 9/1/2007 76 Female 3/6/2008 Other Health Professional United States
Primary
Concomitant
Rash Erythematous Other Serious 1/1/2007 78 Female 179 lb 3/21/2008 Consumer United States
Primary
Concomitant
Hyperhidrosis Other Serious 10/6/2007 76 Female 3/25/2008 Other Health Professional United States
Primary
Concomitant
Vascular Graft Complication Death 3/30/2008 79 Male 181 lb 5/9/2008 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2008 Male 6/6/2008 Pharmacist United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization 5/23/2008 53 Male 6/10/2008 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/21/2008 53 Male 146 lb 6/18/2008 Physician Japan
Primary
Concomitant
Interacting
Haemoptysis Hospitalization 5/23/2008 53 Male 7/2/2008 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/21/2008 53 Male 146 lb 7/8/2008 Physician Japan
Primary
Concomitant
Interacting
Renal Cell Carcinoma Stage Iv Hospitalization 7/15/2008 54 Male 108 lb 10/17/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/24/2008 69 Female 110 lb 10/30/2008 Physician Japan
Primary
Concomitant
Pharyngeal Haemorrhage Other Serious 5/1/2008 59 Male 146 lb 11/21/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 54 Female 11/21/2008 Physician United States
Primary
Concomitant
Pharyngeal Haemorrhage Other Serious 5/1/2008 59 Male 146 lb 11/24/2008 Physician Japan
Primary
Concomitant
Malaise Hospitalization 4/7/2008 76 Female 86 lb 12/23/2008 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 5/6/2008 84 Male 132 lb 2/20/2009 United States
Primary
Concomitant
Vasculitis Other Serious 2/1/2008 65 Male 196 lb 3/25/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 54 Female 4/6/2009 Physician United States
Primary
Concomitant
Troponin Increased Hospitalization 3/13/2009 55 Male 218 lb 4/20/2009 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 3/13/2009 55 Male 218 lb 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 2/20/2009 58 Male 7/21/2009 United States
Primary
Concomitant
Skin Fissures Disability 8/1/2009 37 Female 9/22/2009 United States
Primary
Concomitant
Skin Fissures Disability 8/1/2009 37 Female 10/15/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/5/2009 55 Male 158 lb 9/2/2009 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Disability 9/25/2009 80 Male 198 lb 11/3/2009 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal Disability 9/25/2009 80 Male 198 lb 11/4/2009 Physician Germany
Primary
Concomitant
Pruritus Disability 9/25/2009 80 Male 198 lb 11/18/2009 Physician Germany
Primary
Concomitant
Vasomotor Rhinitis Other Serious 5/1/2008 43 Female 12/17/2009 Consumer France
Primary
Concomitant
Vulval Disorder Other Serious 12/10/2007 80 Male 137 lb 12/31/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 63 Male 3/26/2010 Other Health Professional United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 63 Male 3/30/2010 Other Health Professional United States
Primary
Concomitant
Hypertension Life Threatening 2/1/2010 Male 4/8/2010 Physician China
Primary
Concomitant
Rash Papular Hospitalization 8/1/2009 56 Male 181 lb 4/16/2010 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious Female 64 lb 6/3/2010 Other Health Professional Austria
Primary
Concomitant
Speech Disorder Life Threatening 3/18/2010 68 Female 115 lb 6/4/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious Female 64 lb 6/4/2010 Other Health Professional Austria
Primary
Concomitant
Encephalopathy Hospitalization Female 6/4/2010 Physician United States
Primary
Concomitant
Walking Aid User 6/30/2010 93 Male 7/14/2010 Other Health Professional United States
Primary
Concomitant
Thyroid Cancer Other Serious 5/17/2010 34 Female 8/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thyroid Cancer Other Serious 5/17/2010 34 Female 8/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/11/2010 72 Male 183 lb 8/18/2010 Physician Germany
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/11/2010 72 Male 183 lb 8/19/2010 Physician Germany
Primary
Concomitant
Thyroid Cancer Other Serious 5/17/2010 34 Female 8/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Dehydration Hospitalization 5/25/2010 72 Male 174 lb 9/16/2010 Sweden
Primary
Concomitant
Swollen Tongue Hospitalization 8/5/2010 66 Male 10/6/2010 Physician Germany
Primary
Secondary
Concomitant
Encephalopathy Hospitalization Female 10/20/2010 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/16/2009 53 Female 126 lb 11/2/2010 Physician Japan
Primary
Concomitant
Multi-organ Failure Hospitalization 11/14/2010 73 Female 11/23/2010 Physician United States
Primary
Concomitant
Abdominal Pain Male 1/12/2011 Pharmacist United States
Primary
Concomitant
Arthritis Disability 9/4/2010 59 Male 231 lb 2/4/2011 Consumer Brazil
Primary
Concomitant
Death Death Female 2/17/2011 United States
Primary
Concomitant
Pain Disability 9/4/2010 59 Male 231 lb 3/25/2011 Consumer Brazil
Primary
Concomitant
Renal Failure Hospitalization 9/1/2010 77 Male 3/31/2011 Consumer United States
Primary
Secondary
Concomitant
Necrotising Fasciitis Hospitalization 10/5/2009 51 Female 209 lb 4/15/2011 Consumer Germany
Primary
Concomitant
Skin Ulcer Hospitalization 6/1/2010 62 Male 4/20/2011 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/1/2010 62 Male 5/2/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/13/2010 66 Female 163 lb 5/10/2011 Other Health Professional Germany
Primary
Concomitant
Chest Pain Hospitalization 6/14/2010 57 Female 272 lb 5/11/2011 Consumer United States
Primary
Concomitant
Mucosal Inflammation Other Serious 12/20/2010 79 Female 141 lb 5/13/2011 Physician Germany
Primary
Concomitant
Alopecia Hospitalization 6/12/2008 51 Male 203 lb 5/18/2011 Physician Japan
Primary
Secondary
Concomitant
Pain Of Skin Other Serious 3/23/2011 63 Female 130 lb 5/30/2011 Pharmacist Brazil
Primary
Concomitant
Convulsion Hospitalization 11/25/2010 70 Female 126 lb 6/3/2011 Other Health Professional Spain
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 10/17/2010 81 Male 139 lb 6/3/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 6/1/2010 62 Male 6/6/2011 Consumer United States
Primary
Concomitant
Blood Albumin Decreased Other Serious 9/4/2010 59 Male 231 lb 6/10/2011 Consumer Brazil
Primary
Concomitant
Bone Pain Other Serious Male 6/14/2011 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious Male 6/16/2011 Consumer United States
Primary
Concomitant
Mental Status Changes Other Serious Male 6/24/2011 Consumer United States
Primary
Concomitant
Exposed Bone In Jaw Death Male 6/28/2011 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious Male 6/29/2011 Lawyer United States
Primary
Concomitant
Insomnia Other Serious 3/23/2011 63 Female 130 lb 7/6/2011 Pharmacist Brazil
Primary
Concomitant
Osteoarthritis Other Serious Male 7/12/2011 Physician United States
Primary
Concomitant
Constipation Other Serious Male 7/14/2011 Lawyer United States
Primary
Concomitant
Rash Other Serious 3/23/2011 63 Female 130 lb 7/18/2011 Pharmacist Brazil
Primary
Concomitant
Metaplasia Other Serious Male 7/19/2011 Consumer United States
Primary
Concomitant
Constipation Death Male 7/21/2011 Physician United States
Primary
Concomitant
Cerebral Infarction Other Serious 6/28/2011 82 Male 128 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 4/25/2011 72 Male 101 lb 8/4/2011 Physician Japan
Primary
Concomitant
Denture Wearer Death Male 8/5/2011 Consumer United States
Primary
Concomitant
Fall Death Male 8/8/2011 Physician United States
Primary
Concomitant
Dizziness Other Serious 6/2/2011 69 Female 123 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Vomiting 7/1/2011 50 Female 8/11/2011 Pharmacist United States
Primary
Concomitant
Lymphopenia Other Serious 5/9/2011 79 Male 148 lb 9/1/2011 Physician Germany
Primary
Concomitant
Cerebrovascular Accident Hospitalization 6/25/2010 66 Female 163 lb 9/8/2011 Physician Germany
Primary
Concomitant
Platelet Count Decreased 5/23/2011 77 Male 115 lb 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 6/20/2010 60 Male 154 lb 9/13/2011 Physician Japan
Primary
Concomitant
Nausea Other Serious 3/23/2011 63 Female 130 lb 9/13/2011 Pharmacist Brazil
Primary
Concomitant
Chest Discomfort 7/5/2011 55 Male 10/10/2011 Pharmacist United States
Primary
Concomitant
Abdominal Pain Male 10/18/2011 Pharmacist United States
Primary
Concomitant
Dysphagia Disability 5/28/2011 75 Male 106 lb 10/26/2011 Physician Japan
Primary
Concomitant
Gait Disturbance Hospitalization 5/28/2011 75 Male 106 lb 11/1/2011 Physician Japan
Primary
Concomitant
Haematemesis Disability Male 177 lb 11/16/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious Male 177 lb 11/21/2011 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 3/1/2011 53 Female 11/23/2011 Physician United States
Primary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 2/27/2009 47 Male 112 lb 11/24/2011 Physician Japan
Primary
Concomitant
Confusional State Other Serious 10/6/2011 60 Male 179 lb 11/23/2011 Consumer Brazil
Primary
Concomitant
Haemorrhoids Hospitalization 11/18/2011 62 Male 365 lb 12/5/2011 Consumer United States
Primary
Concomitant
Drug Tolerance Other Serious 9/1/2011 70 Male 12/23/2011 Other Health Professional France
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 11/18/2011 62 Male 365 lb 1/2/2012 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Death 12/1/2010 73 Male 141 lb 1/19/2012 Physician Japan
Primary
Concomitant
Appendicectomy Hospitalization 1/19/2012 73 Male 186 lb 1/25/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Joint Swelling Other Serious Male 177 lb 1/25/2012 Lawyer United States
Primary
Concomitant
Pneumonia Other Serious Male 177 lb 2/3/2012 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 1/1/2011 Female 172 lb 2/8/2012 Consumer Belgium
Primary
Concomitant
Joint Swelling Other Serious Male 177 lb 2/10/2012 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 1/1/2011 Female 172 lb 2/14/2012 Physician Belgium
Primary
Concomitant
Femur Fracture Hospitalization Male 177 lb 2/16/2012 Lawyer United States
Primary
Concomitant
Diarrhoea Other Serious 1/1/2011 Female 172 lb 2/24/2012 Physician Belgium
Primary
Concomitant
Arteriosclerosis Hospitalization Male 177 lb 3/7/2012 Physician United States
Primary
Concomitant
Amnesia Other Serious 12/18/2011 79 Male 180 lb 3/9/2012 Physician United States
Primary
Concomitant
Cardiac Failure Chronic Other Serious 2/7/2012 78 Male 112 lb 3/13/2012 Physician Japan
Primary
Concomitant
Hiccups Death 10/6/2011 60 Male 179 lb 3/20/2012 Consumer Brazil
Primary
Concomitant
Hypothyroidism Hospitalization Male 177 lb 3/29/2012 Lawyer United States
Primary
Concomitant
Abdominal Pain Other Serious Male 177 lb 4/3/2012 Physician United States
Primary
Concomitant
Joint Swelling Other Serious 4/13/2011 80 Male 177 lb 4/4/2012 Lawyer United States
Primary
Concomitant
Liver Disorder Other Serious 5/17/2010 58 Male 123 lb 4/4/2012 Physician Japan
Primary
Concomitant
Death Death 3/6/2012 59 Female 4/10/2012 Other Health Professional United States
Primary
Concomitant
Arthralgia 46 Male 4/10/2012 United States
Primary
Concomitant
Pulmonary Embolism Death 10/27/2010 60 Male 4/13/2012 Consumer Venezuela
Primary
Concomitant
Hypokalaemia Other Serious 4/13/2011 80 Male 177 lb 4/16/2012 Lawyer United States
Primary
Concomitant
Hepatic Calcification Death 4/13/2011 80 Male 177 lb 4/27/2012 Physician United States
Primary
Concomitant
Hydrocephalus Death 10/28/2011 57 Male 127 lb 5/3/2012 Pharmacist United States
Primary
Concomitant
Clostridium Difficile Colitis Death 3/1/2012 94 Male 5/7/2012 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/1/2012 77 Male 152 lb 5/14/2012 Physician France
Primary
Secondary
Concomitant
Retinal Vein Thrombosis Other Serious 3/1/2012 77 Male 152 lb 5/17/2012 Physician France
Primary
Secondary
Concomitant
Malaise Hospitalization 1/1/2012 33 Female 106 lb 5/22/2012 Physician Spain
Primary
Concomitant
Hyperkeratosis Death 4/13/2011 80 Male 177 lb 5/24/2012 Lawyer United States
Primary
Concomitant
Open Wound Hospitalization 12/1/2011 65 Male 6/18/2012 Other Health Professional France
Primary
Concomitant
Malaise Other Serious 1/1/2012 33 Female 106 lb 6/19/2012 Physician Spain
Primary
Concomitant

Drug Data