Levothyroxine Sodium combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vitamin B Complex Deficiency Hospitalization 6/1/2001 64 Female 351 lb 1/23/2006 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious 5/1/2005 45 Male 288 lb 1/23/2006 United States
Primary
Concomitant
Skin Discolouration Required Intervention 8/23/2005 Female 9/2/2005 United States
Primary
Concomitant
Tachyarrhythmia Life Threatening 12/3/2005 Female 1/26/2006 France
Primary
Concomitant
Urinary Tract Infection Other Serious 81 Male 1/23/2006 Pharmacist Canada
Primary
Concomitant
Haematuria Life Threatening 11/16/2005 88 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Hospitalization 52 Male 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
Insomnia 10/1/2005 83 Male 155 lb 1/5/2006 Consumer United States
Primary
Concomitant
Insomnia 10/29/2005 60 Female 1/5/2006 Consumer United States
Primary
Concomitant
Hyperhidrosis Life Threatening 48 Male 2/23/2006 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/10/2005 84 Female 148 lb 1/16/2006 Pharmacist United States
Primary
Concomitant
Rash Macular Hospitalization 10/26/2005 76 Male 243 lb 12/7/2005 Pharmacist United States
Primary
Concomitant
Muscle Rigidity Hospitalization 12/11/2005 Male 2/22/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 180 lb 2/22/2006 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/11/2005 Female 167 lb 3/13/2006 Physician United States
Primary
Concomitant
Hyperkalaemia Required Intervention 3/6/2006 79 Male 184 lb 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vertigo Life Threatening 12/3/2005 Female 3/17/2006 Physician France
Primary
Concomitant
Venous Thrombosis Other Serious 5/1/2005 44 Male 250 lb 3/21/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Death 3/15/2005 62 Male 3/27/2006 Physician Canada
Primary
Secondary
Concomitant
Panic Disorder Hospitalization 1/1/2002 37 Female 214 lb 4/17/2006 Lawyer Canada
Primary
Concomitant
Renal Failure Acute Other Serious 3/28/2006 Female 192 lb 4/17/2006 United States
Primary
Secondary
Concomitant
Blood Glucose Decreased Hospitalization 4/14/2006 85 Male 194 lb 4/27/2006 Pharmacist United States
Primary
Concomitant
Hyperhidrosis Other Serious 48 Male 5/18/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2006 81 Female 181 lb 5/31/2006 Consumer United States
Primary
Secondary
Concomitant
Hyperhidrosis Life Threatening 48 Male 5/24/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 3/30/2006 65 Female 5/12/2006 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 69 Female 176 lb 6/8/2006 Canada
Primary
Concomitant
Myasthenia Gravis Other Serious 4/27/2006 84 Male 165 lb 6/9/2006 Pharmacist Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/19/2006 81 Male 110 lb 7/14/2006 Pharmacist United States
Primary
Concomitant
Anaphylactoid Reaction Hospitalization 2/3/2006 75 Male 161 lb 5/24/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2006 56 Male 190 lb 7/19/2006 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/1/2006 62 Female 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2006 57 Male 190 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 81 Male 8/2/2006 Pharmacist Canada
Primary
Concomitant
Urinary Tract Infection Life Threatening 81 Male 8/2/2006 Pharmacist Canada
Primary
Concomitant
Swollen Tongue Other Serious 8/11/2006 63 Female 8/17/2006 Consumer United States
Primary
Concomitant
Hypotension Life Threatening 48 Male 8/19/2006 United Kingdom
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 8/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Myoglobin Blood Increased Other Serious 53 Female 8/29/2006 Other Health Professional Germany
Primary
Concomitant
Pain Other Serious 8/20/2006 Female 9/15/2006 Physician Canada
Primary
Concomitant
Hypotension Other Serious Male 9/15/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/19/2006 62 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 11/22/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 60 Female 182 lb 11/22/2006 Pharmacist United Kingdom
Primary
Concomitant
Epistaxis Hospitalization 8/31/2006 84 Male 1/10/2007 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 12/14/2005 65 Female 190 lb 2/12/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 2/19/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 2/21/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 5/14/2007 Physician Poland
Primary
Concomitant
Syncope Other Serious 1/1/2005 65 Female 190 lb 5/16/2007 Physician Poland
Primary
Concomitant
Rhabdomyolysis Other Serious 4/16/2007 67 Male 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Foetal Distress Syndrome Other Serious 5/31/2007 Physician United States
Primary
Concomitant
Infection Hospitalization 1/1/2007 65 Male 6/5/2007 Physician United States
Primary
Concomitant
Transaminases Increased Other Serious 73 Female 9/24/2007 Pharmacist United States
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 11/24/2006 72 Female 9/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/23/2007 24 Male 110 lb 10/3/2007 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5/31/2006 73 Female 10/3/2007 Other Health Professional France
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 1/7/2007 74 Female 10/2/2007 Denmark
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2007 24 Male 110 lb 10/16/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 123 lb 10/17/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 2/15/2007 50 Female 10/16/2007 Consumer United States
Primary
Concomitant
Insomnia 1/1/2006 74 Male 147 lb 10/5/2007 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 8/2/2007 65 Female 236 lb 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization 5/1/2007 75 Female 10/26/2007 Consumer Sweden
Primary
Concomitant
Paraesthesia Oral Other Serious 10/26/2006 53 Female 103 lb 11/17/2007 Physician Canada
Primary
Concomitant
Oral Intake Reduced Hospitalization 11/12/2007 Female 138 lb 11/14/2007 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 4/1/2007 Female 161 lb 11/21/2007 Germany
Primary
Concomitant
General Physical Health Deterioration Other Serious 4/1/2007 Female 161 lb 11/26/2007 Germany
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 11/20/2007 Consumer United States
Primary
Concomitant
Tachyarrhythmia Other Serious 6/1/2007 65 Female 11/28/2007 Consumer United States
Primary
Secondary
Concomitant
Lethargy Required Intervention 10/24/2007 93 Male 179 lb 10/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 65 Female 12/3/2007 Consumer Canada
Primary
Concomitant
Rash Pruritic 5/24/2007 52 Female 300 lb 11/16/2007 Physician United States
Primary
Concomitant
Torsade De Pointes Hospitalization 91 Female 12/10/2007 Belgium
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 91 12/8/2007 Other Health Professional Belgium
Primary
Secondary
Drug Ineffective 9/1/2007 Female 200 lb 12/14/2007 Consumer United States
Primary
Concomitant
Injection Site Pain Female 220 lb 12/14/2007 Consumer United States
Primary
Concomitant
Underdose 1/1/2004 Male 241 lb 12/15/2007 Consumer United States
Primary
Concomitant
Torsade De Pointes Life Threatening 91 12/18/2007 Other Health Professional Germany
Primary
Secondary
Torsade De Pointes Life Threatening 91 12/21/2007 Germany
Primary
Secondary
Hypertension Other Serious 3/22/2005 86 Female 12/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/1/2007 93 Female 12/27/2007 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 91 12/28/2007 Other Health Professional Germany
Primary
Secondary
Abdominal Wall Abscess Hospitalization 3/29/2007 Female 134 lb 12/28/2007 United Kingdom
Primary
Concomitant
Loss Of Consciousness Life Threatening 12/20/2007 81 Female 12/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 91 Female 1/9/2008 Other Health Professional France
Primary
Secondary
Syncope Other Serious 8/1/2004 65 Female 190 lb 1/9/2008 Physician Poland
Primary
Concomitant
Rash Maculo-papular Hospitalization 1/1/2007 Male 602 lb 1/23/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 60 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Rash Maculo-papular Hospitalization 1/1/2007 Male 602 lb 2/4/2008 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 79 Female 4/4/2008 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 79 Female 4/11/2008 Physician United States
Primary
Concomitant
Toothache Other Serious 9/24/2001 73 Female 152 lb 4/18/2008 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Life Threatening 1/1/2006 79 Female 150 lb 5/2/2008 Physician United States
Primary
Concomitant
Toothache Other Serious 9/24/2001 73 Female 152 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Death Death 4/22/2008 83 Male 5/29/2008 United States
Primary
Concomitant
Poor Peripheral Circulation Hospitalization 5/9/2007 Female 6/2/2008 Physician United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 9/3/2007 6/12/2008 Consumer Canada
Primary
Secondary
Concomitant
Renal Failure Death 86 Female 6/9/2008 Other Health Professional Norway
Primary
Concomitant
Muscle Disorder 5/1/2008 84 Female 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Erythematous 3/16/2008 Female 212 lb 6/12/2008 Physician United States
Primary
Concomitant
Swelling Other Serious 1/1/2007 Female 155 lb 6/12/2008 Consumer United States
Primary
Concomitant
Urticaria 5/11/2008 Female 140 lb 6/13/2008 Consumer United States
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/2004 Female 6/13/2008 France
Primary
Concomitant
Weight Increased Hospitalization Female 6/4/2008 Physician United States
Primary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 6/4/2008 Physician United States
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 76 Male 6/13/2008 France
Primary
Secondary
Concomitant
Abdominal Pain 3/19/2008 63 Female 194 lb 6/16/2008 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 2/1/2006 53 Female 6/18/2008 Consumer United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 3/16/2008 82 Male 6/23/2008 Other Health Professional United States
Primary
Concomitant
Skin Haemorrhage 1/1/2008 Male 6/23/2008 Consumer United States
Primary
Concomitant
Toothache Other Serious 9/24/2001 73 Female 152 lb 6/24/2008 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2003 83 Female 134 lb 6/24/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/7/2008 Female 176 lb 6/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urine Analysis Abnormal Other Serious 10/23/2007 Female 126 lb 6/25/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased 62 Female 233 lb 6/26/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/7/2008 Female 176 lb 6/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2003 83 Female 134 lb 6/27/2008 Consumer United States
Primary
Concomitant
Pruritus Generalised 5/5/2008 83 Female 152 lb 6/30/2008 Other Health Professional United States
Primary
Concomitant
Nephropathy Toxic Hospitalization 5/8/2008 69 Male 157 lb 6/29/2008 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Other Serious 8/1/2004 65 Female 190 lb 7/7/2008 Physician Poland
Primary
Concomitant
Drug Ineffective 85 Female 7/29/2008 Consumer United States
Primary
Concomitant
Drug Screen Negative 2/5/2008 55 Male 170 lb 7/29/2008 Consumer United States
Primary
Concomitant
Interacting
Heart Rate Irregular Other Serious 1/18/2007 Male 8/1/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/14/2007 Female 123 lb 8/4/2008 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 78 Female 187 lb 8/15/2008 United States
Primary
Secondary
Concomitant
Drug Ineffective 87 Female 8/15/2008 United States
Primary
Concomitant
Malaise Required Intervention 92 Male 160 lb 9/12/2008 Physician United States
Primary
Concomitant
Intra-abdominal Haematoma Hospitalization 8/1/2008 67 Female 256 lb 9/26/2008 Other Health Professional United States
Primary
Concomitant
Tinnitus Hospitalization Male 200 lb 11/10/2008 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Required Intervention 5/28/2008 Male 149 lb 6/23/2008 United States
Primary
Concomitant
Tremor Other Serious 10/8/2008 60 Female 125 lb 12/2/2008 Pharmacist Canada
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 2/1/2008 Female 114 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 1/1/2008 Male 321 lb 12/3/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 6/1/2008 Female 190 lb 12/12/2008 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 11/28/2008 Male 12/12/2008 United States
Primary
Concomitant
Injection Site Urticaria 9/18/2008 Female 175 lb 12/12/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 12/12/2008 Consumer Germany
Primary
Concomitant
Drug Ineffective 8/29/2008 Female 162 lb 12/12/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 6/1/2008 Female 12/12/2008 Consumer United States
Primary
Concomitant
Rash 7/1/2008 Female 267 lb 12/12/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 10/21/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased 8/2/2006 Female 195 lb 12/15/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 10/1/2007 Female 162 lb 12/23/2008 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 12/4/2008 Female 12/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2008 73 Female 160 lb 12/31/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2007 Female 162 lb 12/24/2008 Consumer United States
Primary
Concomitant
Osteomyelitis Other Serious 1/1/2008 Female 219 lb 1/8/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/1/2007 Female 229 lb 1/8/2009 Physician United States
Primary
Concomitant

Drug Data