Levothyroxine Sodium combined with Metoprolol Tartrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Aneurysm Death 43 Male 1/11/2006 United States
Primary
Concomitant
Nausea Hospitalization 1/2/2006 Female 198 lb 1/18/2006 United States
Primary
Concomitant
Vomiting Other Serious 11/30/2005 85 Female 143 lb 12/9/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/9/2005 85 Female 143 lb 12/9/2005 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 1/2/2006 Female 198 lb 2/27/2006 Physician United States
Primary
Concomitant
Metastases To Liver Hospitalization 5/4/2005 84 Male 159 lb 2/27/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/11/2005 61 Female 3/2/2006 Physician Sweden
Primary
Concomitant
Weight Decreased Other Serious 11/24/2000 Female 128 lb 3/10/2006 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 1/1/2005 64 Male 270 lb 12/27/2005 Physician United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 8/29/2004 75 Female 170 lb 12/29/2005 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/22/2006 85 Female 153 lb 2/22/2006 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 85 Male 3/27/2006 Physician Denmark
Primary
Concomitant
Vomiting Hospitalization 5/4/2005 84 Male 159 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/10/2006 56 Female 140 lb 4/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 Female 4/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/1/2006 Female 4/25/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Life Threatening 4/29/2005 76 Female 143 lb 4/19/2006 Physician Germany
Primary
Secondary
Concomitant
Retinal Vascular Thrombosis Hospitalization 2/1/2004 74 Male 4/28/2006 Norway
Primary
Concomitant
Cerebral Infarction Hospitalization 3/19/2004 72 Female 4/28/2006 Norway
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/2/2002 62 Male 4/28/2006 Norway
Primary
Concomitant
Tachycardia Hospitalization 12/1/2001 63 Male 4/28/2006 Norway
Primary
Concomitant
Road Traffic Accident Hospitalization 1/1/2003 71 Female 203 lb 5/1/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Other Serious 3/22/2005 81 Female 4/27/2006 Canada
Primary
Concomitant
Blood Potassium Increased Life Threatening 2/21/2006 62 Female 223 lb 2/24/2006 United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/16/2006 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea 1/25/2006 63 Female 188 lb 4/6/2006 Other Health Professional United States
Primary
Concomitant
Insomnia 10/29/2005 60 Female 135 lb 4/3/2006 Consumer United States
Primary
Concomitant
Hypocalcaemia Hospitalization 12/18/2005 71 Male 3/13/2006 Physician United States
Primary
Concomitant
Pruritus Hospitalization 4/1/2006 Female 141 lb 6/14/2006 Physician Germany
Primary
Concomitant
Myasthenia Gravis Other Serious 4/27/2006 83 Male 165 lb 6/16/2006 Pharmacist Canada
Primary
Concomitant
Viral Infection Hospitalization 69 Female 176 lb 6/16/2006 Canada
Primary
Concomitant
Interacting
International Normalised Ratio Increased Hospitalization 4/24/2006 67 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 69 Male 6/30/2006 Physician United States
Primary
Concomitant
Post Procedural Complication Hospitalization 9/1/2005 39 Male 7/10/2006 Norway
Primary
Secondary
Concomitant
Leukopenia Life Threatening 10/5/2005 72 Male 263 lb 4/26/2006 United States
Primary
Concomitant
Wheezing Hospitalization 7/14/2006 87 Male 161 lb 8/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sinus Operation Hospitalization 9/1/2005 39 Male 7/28/2006 Norway
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 8/9/2006 United Kingdom
Primary
Secondary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 8/10/2006 Consumer Canada
Primary
Concomitant
Thyroid Operation Other Serious 5/1/2006 71 Male 8/11/2006 Physician Germany
Primary
Concomitant
Thyroid Operation Other Serious 5/1/2006 71 Male 8/11/2006 Physician Germany
Primary
Concomitant
Renal Disorder Hospitalization Female 8/14/2006 Consumer Canada
Primary
Concomitant
Hypotension Life Threatening 48 Male 8/16/2006 United Kingdom
Primary
Secondary
Concomitant
Tooth Fracture Other Serious Female 185 lb 8/14/2006 United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 8/16/2006 United Kingdom
Primary
Secondary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 8/24/2006 Physician United States
Primary
Concomitant
Wheezing Life Threatening 81 Male 8/17/2006 Canada
Primary
Concomitant
Weight Decreased Other Serious 69 Male 8/23/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/10/2006 56 Female 140 lb 8/21/2006 Physician United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 8/19/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Required Intervention 8/7/2006 72 Male 194 lb 8/30/2006 Pharmacist United States
Primary
Concomitant
Sedation 2/1/2006 83 Male 9/6/2006 Consumer United States
Primary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 9/8/2006 Consumer Canada
Primary
Concomitant
Swollen Tongue Other Serious 8/11/2006 63 Female 9/11/2006 Consumer United States
Primary
Concomitant
Nausea Other Serious 4/3/2006 Female 9/6/2006 United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 9/13/2006 Physician United States
Primary
Concomitant
Cholecystitis Hospitalization 8/23/2006 Female 9/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Disorder Life Threatening 4/20/2005 85 Male 150 lb 9/22/2006 Pharmacist United States
Primary
Concomitant
Hypotension Life Threatening 48 Male 9/21/2006 United Kingdom
Primary
Secondary
Concomitant
Glossitis Hospitalization 4/22/2006 70 Male 10/4/2006 Physician Austria
Primary
Concomitant
Sinus Disorder Hospitalization 9/1/2005 39 Male 9/28/2006 Norway
Primary
Secondary
Concomitant
Hypotension Hospitalization 7/6/2006 85 Male 172 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Other Serious 12/1/2005 71 Female 10/9/2006 Other Health Professional United States
Primary
Concomitant
Blood Potassium Increased 5/1/2006 81 Female 181 lb 10/10/2006 Consumer United States
Primary
Concomitant
Hypotension Life Threatening 48 Male 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 48 Male 10/13/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/3/2006 Male 224 lb 10/10/2006 United States
Primary
Concomitant
Scar Other Serious 8/1/2006 Female 10/16/2006 Physician United States
Primary
Concomitant
Hypotension Life Threatening 48 Male 10/10/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 7/29/2006 77 Male 10/12/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/10/2006 56 Female 140 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Dyspnoea 5/1/2006 83 Male 8/22/2006 United States
Primary
Concomitant
Drug Ineffective 1/1/2005 82 Female 8/22/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 63 Female 10/26/2006 Other Health Professional Australia
Primary
Secondary
Death Death 8/21/2006 81 Female 10/26/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 10/1/2006 79 Female 10/31/2006 United States
Primary
Concomitant
Renal Failure Life Threatening 5/21/2006 81 Female 244 lb 10/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Shunt Occlusion Hospitalization 7/18/2006 Female 11/7/2006 Consumer Canada
Primary
Concomitant
Vomiting 9/21/2006 64 Female 11/9/2006 Physician Colombia
Primary
Concomitant
Epilepsy Hospitalization 9/16/2006 67 Male 11/3/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hypotension Life Threatening 48 Male 11/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Cardiac Murmur Hospitalization 4/24/2006 Female 160 lb 11/16/2006 Consumer Canada
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 76 Female 150 lb 11/13/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 9/5/2005 73 Female 11/14/2006 Germany
Primary
Secondary
Concomitant
Off Label Use Other Serious 9/1/2006 82 Female 128 lb 11/29/2006 Physician Switzerland
Primary
Concomitant
Colon Adenoma Other Serious 9/1/2006 60 Female 185 lb 12/6/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 6/4/2005 61 Female 12/5/2006 Physician Sweden
Primary
Concomitant
Hypotension Life Threatening 48 Male 12/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 11/24/2006 72 Female 12/18/2006 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/6/2006 Female 163 lb 12/28/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/24/2006 72 Female 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 12/31/2006 Male 120 lb 1/8/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Death 12/31/2006 66 Male 120 lb 1/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/21/2006 10/19/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/14/2006 80 Male 240 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Somnolence Hospitalization 11/6/2006 85 Male 1/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Swelling Hospitalization 1/16/2007 78 Male 194 lb 1/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 11/30/2006 80 Female 181 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Death Death 63 Male 1/23/2007 Consumer Canada
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/8/2007 81 Male 113 lb 1/22/2007 Consumer United States
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 11/10/2006 Female 2/2/2007 Physician Belgium
Primary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 196 lb 2/6/2007 Physician United States
Primary
Secondary
Concomitant
Death Hospitalization 12/31/2006 Male 120 lb 2/7/2007 Physician United States
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 196 lb 2/13/2007 Physician United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 1/22/2007 82 Male 3/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Death 1/1/2007 90 Female 2/26/2007 Physician United States
Primary
Concomitant
Swelling Hospitalization 11/14/2006 Female 180 lb 3/5/2007 Consumer Canada
Primary
Concomitant
Sepsis Hospitalization 10/1/2006 Female 173 lb 3/16/2007 Physician United States
Primary
Concomitant
Rash Hospitalization 6/6/2006 Female 163 lb 4/18/2007 Physician United States
Primary
Concomitant
Rash Hospitalization 9/1/2006 Female 186 lb 5/1/2007 Physician United States
Primary
Concomitant
Osteoarthritis Required Intervention 9/13/2006 71 Male 231 lb 4/26/2007 Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 63 Female 5/16/2007 Other Health Professional Australia
Primary
Secondary
Rash Hospitalization 6/6/2006 Female 163 lb 5/17/2007 Physician United States
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2007 Male 245 lb 5/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/27/2007 Female 6/11/2007 Physician United States
Primary
Concomitant
Underdose 1/25/2007 55 Male 220 lb 5/11/2007 Consumer United States
Primary
Concomitant
Dizziness Life Threatening 7/1/2006 82 Male 208 lb 6/7/2007 Pharmacist United States
Primary
Concomitant
Urinary Retention Hospitalization 2/20/2006 61 Female 224 lb 6/5/2007 Physician United States
Primary
Concomitant
Osteoarthritis Required Intervention 4/1/2006 71 Male 231 lb 4/26/2007 Consumer Germany
Primary
Concomitant
Urinary Incontinence Other Serious 72 Female 6/21/2007 Canada
Primary
Concomitant
Urinary Retention Hospitalization 2/20/2006 61 Female 224 lb 6/21/2007 Consumer United States
Primary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 6/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 6/1/2007 Male 7/20/2007 Consumer Germany
Primary
Secondary
Concomitant
Palpitations Female 7/23/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/24/2006 72 Female 7/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 6/18/2007 79 Female 7/30/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting 6/3/2007 67 Female 198 lb 7/11/2007 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2006 72 Female 187 lb 8/30/2007 Pharmacist Canada
Primary
Concomitant
Syncope Other Serious 1/7/2007 39 Male 224 lb 9/7/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pruritus 5/24/2007 52 Female 8/16/2007 United States
Primary
Concomitant
Nephrocalcinosis Other Serious 4/1/2005 60 Female 118 lb 9/21/2007 Physician United States
Primary
Concomitant
Syncope Other Serious 1/7/2007 39 Male 224 lb 9/24/2007 Pharmacist United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 2/15/2007 50 Female 9/27/2007 Consumer United States
Primary
Concomitant
Superior Vena Caval Occlusion Other Serious 8/23/2007 Female 10/5/2007 Physician United States
Primary
Concomitant
Drug Ineffective 7/1/2007 71 Male 165 lb 10/4/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 63 Female 10/8/2007 Other Health Professional Australia
Primary
Secondary
Nephrogenic Systemic Fibrosis Death 11/17/2005 51 Female 10/8/2007 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 9/11/2007 Female 142 lb 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 73 Female 10/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/15/2005 Male 183 lb 11/7/2007 Physician Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/6/2007 76 Male 179 lb 11/7/2007 Physician Germany
Primary
Concomitant
Zinc Deficiency Hospitalization 12/1/2006 78 Female 11/8/2007 Consumer France
Primary
Concomitant
Torsade De Pointes Hospitalization 91 Female 11/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 123 lb 11/19/2007 Physician United States
Primary
Concomitant
Osteoarthritis Required Intervention 4/1/2006 71 Male 231 lb 12/21/2007 Consumer Germany
Primary
Concomitant
Injection Site Pain 5/25/2007 67 Female 198 lb 10/8/2007 Consumer United States
Primary
Concomitant
Torsade De Pointes Life Threatening 91 Female 1/4/2008 Germany
Primary
Secondary
Platelet Count Decreased Other Serious 1/2/2008 87 Female 123 lb 1/8/2008 Pharmacist United States
Primary
Concomitant
Lip Swelling Other Serious 9/23/2007 58 Male 230 lb 12/12/2007 Other Health Professional United States
Primary
Concomitant

Drug Data