Levothyroxine Sodium combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Life Threatening 4/22/2005 Male 254 lb 2/13/2006 United States
Primary
Concomitant
Tinnitus Hospitalization 9/1/2005 74 Female 3/20/2006 Consumer New Zealand
Primary
Concomitant
Hyperhidrosis Life Threatening 48 Male 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Pseudomonal Life Threatening 4/29/2005 76 Female 143 lb 4/19/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 69 Male 5/18/2006 United States
Primary
Concomitant
Respiratory Failure Other Serious 10/1/2005 74 Female 5/8/2006 Canada
Primary
Concomitant
Weight Decreased Other Serious 10/1/2005 74 Female 5/25/2006 Canada
Primary
Concomitant
Tachycardia Hospitalization 67 Female 6/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 69 Male 6/9/2006 Other Health Professional United States
Primary
Concomitant
Cardiomyopathy Life Threatening 4/22/2005 Male 254 lb 6/16/2006 United States
Primary
Concomitant
Incorrect Drug Administration Duration Other Serious Female 200 lb 6/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/11/2005 46 Female 2/7/2006 United States
Primary
Concomitant
Disease Progression Hospitalization 4/17/2006 60 Female 8/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/2/2006 75 Female 187 lb 10/2/2006 Physician Germany
Primary
Concomitant
Condition Aggravated Other Serious 9/1/2006 Female 130 lb 10/11/2006 Consumer United States
Primary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 10/19/2006 Physician Germany
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 11/13/2006 Physician Germany
Primary
Secondary
Concomitant
Blister Hospitalization 3/31/2005 30 Female 11/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sudden Death Death 11/25/2005 69 Female 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 7/29/2006 70 Male 215 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 11/1/2003 Female 187 lb 12/4/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/26/2005 Male 139 lb 12/4/2006 Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/17/2006 57 Female 211 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Other Serious 70 Female 11/30/2006 Physician United States
Primary
Concomitant
Cardiomegaly Other Serious 4/24/2006 Female 160 lb 12/14/2006 Consumer Canada
Primary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 12/18/2006 Physician United States
Primary
Concomitant
Sepsis Syndrome Required Intervention 5/31/2006 70 Female 12/15/2006 Pharmacist United States
Primary
Concomitant
Bone Marrow Failure Other Serious 68 Female 12/7/2006 Canada
Primary
Secondary
Concomitant
Renal Failure Required Intervention 5/16/2006 76 Female 12/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 11/29/2005 64 Male 209 lb 12/12/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization Female 12/21/2006 Physician Canada
Primary
Concomitant
Myasthenia Gravis Other Serious 4/27/2006 83 Male 165 lb 12/22/2006 Pharmacist Canada
Primary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 12/22/2006 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 7/11/2006 72 12/18/2006 Physician Germany
Primary
Concomitant
Myocardial Infarction Life Threatening 12/26/2006 78 Male 215 lb 12/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 10/1/2006 79 Female 1/3/2007 United States
Primary
Concomitant
Pneumonia Death 12/13/2006 72 Male 170 lb 12/28/2006 Physician United States
Primary
Concomitant
Short-bowel Syndrome Hospitalization 11/24/2006 72 Female 12/29/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Required Intervention 8/1/2006 Male 8/7/2006 Pharmacist United States
Primary
Concomitant
Cardiac Failure Hospitalization 9/8/2006 Male 171 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 10/25/2006 59 Female 10/26/2006 United States
Primary
Concomitant
Short-bowel Syndrome Hospitalization 11/24/2006 72 Female 1/10/2007 United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 60 Female 182 lb 1/17/2007 Pharmacist United Kingdom
Primary
Concomitant
Haemorrhage Intracranial Other Serious 6/2/2006 Male 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vertigo Other Serious 4/1/2006 Female 1/16/2007 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 Female 170 lb 1/25/2007 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 68 Male 250 lb 8/17/2006 United States
Primary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 2/16/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Female 163 lb 2/16/2007 Physician Germany
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 10/9/2006 72 Male 164 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/18/2006 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Fatigue Death 1/1/2007 90 Female 2/9/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/2007 Male 237 lb 3/1/2007 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/16/2005 57 Female 3/2/2007 Other Health Professional Sweden
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 8/29/2006 82 Female 131 lb 3/2/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 70 Female 3/1/2007 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 11/1/2006 Male 209 lb 3/8/2007 Consumer United States
Primary
Concomitant
Tongue Blistering Hospitalization 65 Female 3/21/2005 United States
Primary
Secondary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 3/20/2007 Physician United States
Primary
Concomitant
Swelling Face Other Serious 82 Male 121 lb 3/20/2007 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/19/2005 63 Male 3/26/2007 Pharmacist Germany
Primary
Secondary
Concomitant
Papillary Thyroid Cancer Hospitalization 8/10/2006 Male 205 lb 3/27/2007 Physician United States
Primary
Concomitant
Renal Tubular Necrosis Life Threatening 2/6/2007 78 Male 3/23/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/15/2007 77 Female 190 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2007 78 Male 3/26/2007 Physician Germany
Primary
Concomitant
Metastases To Liver Hospitalization 7/17/2006 41 Male 3/27/2007 Germany
Primary
Concomitant
Blood Triglycerides Increased Other Serious 62 Female 222 lb 11/28/2006 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2007 78 Male 3/29/2007 Physician Germany
Primary
Concomitant
Neutropenia Hospitalization 4/3/2007 48 Female 150 lb 4/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/2/2006 82 Female 4/4/2007 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/12/2006 80 Male 162 lb 3/23/2007 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 4/10/2007 54 Female 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 1/1/2006 Female 4/18/2007 United States
Primary
Concomitant
Vomiting Hospitalization 1/3/2007 Female 4/12/2007 Physician Germany
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2006 74 Male 160 lb 4/30/2007 Consumer United States
Primary
Concomitant
Rash Hospitalization 9/1/2006 Female 186 lb 5/1/2007 Physician United States
Primary
Concomitant
Cardiac Disorder Hospitalization 4/14/2007 73 Male 5/3/2007 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 76 Female 5/1/2007
Primary
Concomitant
Renal Failure Acute Hospitalization 1/21/2007 76 Female 157 lb 4/18/2007 Physician United States
Primary
Concomitant
Cerebral Atrophy Other Serious 9/1/2006 Female 119 lb 5/10/2007 Consumer United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 3/1/2007 Female 149 lb 5/14/2007 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 4/30/2007 Male 143 lb 5/15/2007 Malaysia
Primary
Concomitant
Dysuria Other Serious 1/1/2006 Female 161 lb 5/16/2007 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 3/22/2007 Male 153 lb 5/10/2007 Pharmacist United States
Primary
Concomitant
Pain In Extremity Disability 1/1/2005 84 Male 225 lb 12/13/2006 Consumer United States
Primary
Concomitant
Ear Haemorrhage Hospitalization 8/5/2005 80 Female 180 lb 12/13/2006 United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/5/2005 12/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 8/1/2006 72 Female 147 lb 12/13/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 5/5/2007 Male 190 lb 5/25/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 4/29/2007 Male 143 lb 5/25/2007 Malaysia
Primary
Concomitant
Secondary Adrenocortical Insufficiency Hospitalization 11/7/2006 41 Male 179 lb 5/30/2007 Physician Netherlands
Primary
Concomitant
Vomiting Hospitalization 11/2/2006 68 Male 195 lb 2/14/2007 Pharmacist United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 11/17/2005 51 Female 6/3/2007 Physician United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 6/1/2007 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 4/29/2007 Male 143 lb 6/6/2007 Malaysia
Primary
Concomitant
Pneumonia Hospitalization Male 6/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vasospasm Hospitalization 84 Female 6/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2007 73 Male 6/14/2007 Consumer United States
Primary
Concomitant
Wound Dehiscence Hospitalization 8/21/2005 59 Female 6/15/2007 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 72 Female 187 lb 6/24/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Nausea Life Threatening 6/3/2007 Female 154 lb 6/21/2007 Other Health Professional United States
Primary
Concomitant
Medication Residue 82 Female 169 lb 6/25/2007 United States
Primary
Concomitant
Head Injury Other Serious 5/27/2007 Female 131 lb 6/28/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 4/10/2007 54 Female 6/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Column Stenosis Other Serious 4/1/2007 Male 181 lb 7/2/2007 Physician United States
Primary
Concomitant
Incorrect Drug Administration Duration Other Serious Female 200 lb 6/19/2007 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Death 2/25/2007 Female 117 lb 7/5/2007 Germany
Primary
Concomitant
Drug Ineffective Other Serious 5/5/2007 Male 190 lb 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 82 Male 121 lb 7/9/2007 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 4/4/2007 Male 165 lb 7/13/2007 Germany
Primary
Concomitant
Skin Lesion Other Serious 6/24/2007 76 Female 7/17/2007 Consumer United States
Primary
Concomitant
Urinary Retention Other Serious 10/1/2006 Female 161 lb 7/25/2007 Physician United States
Primary
Concomitant
Rash Papular Other Serious 7/24/2007 76 Female 110 lb 7/26/2007 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 7/25/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/1/2007 Male 200 lb 8/1/2007 Physician United States
Primary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 8/2/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization Male 8/6/2007 Physician United States
Primary
Concomitant
Hydronephrosis Hospitalization 7/9/2007 54 Female 181 lb 8/6/2007
Primary
Concomitant
Alveolitis Other Serious 8/28/2006 Female 8/6/2007 Germany
Primary
Concomitant
Amnesia 4/6/2007 65 Male 280 lb 7/10/2007 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/9/2006 67 Female 8/10/2007 United States
Primary
Secondary
Concomitant
Lethargy 3/22/2007 86 Female 110 lb 7/10/2007 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 80 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Myocardial Infarction Other Serious 6/14/2003 78 Female 140 lb 7/9/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/7/2007 74 Female 8/13/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/2/2007 65 Female 236 lb 8/17/2007 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 8/29/2006 Female 131 lb 8/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Drug Withdrawal Syndrome Hospitalization 1/1/2002 40 Female 8/15/2007 Other Health Professional Germany
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 11/16/2005 Female 8/21/2007 Other Health Professional Sweden
Primary
Concomitant
Transaminases Increased Other Serious 5/1/2007 76 Male 8/22/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/5/2007 Male 190 lb 8/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Infusion Related Reaction Life Threatening 7/16/2007 84 Male 8/22/2007 Pharmacist United States
Primary
Concomitant
Drug Ineffective Required Intervention 4/8/2007 54 Female 96 lb 5/4/2007 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 4/4/2007 Male 165 lb 8/31/2007 Germany
Primary
Concomitant
Visual Field Defect Other Serious 11/18/2005 Female 8/31/2007 Physician Germany
Primary
Concomitant
Pseudocyst Hospitalization 12/21/2006 62 Male 182 lb 8/28/2007 Physician United States
Primary
Concomitant
Vomiting Life Threatening 12/24/2006 Female 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Alveolitis Other Serious 8/28/2006 Female 9/6/2007 Germany
Primary
Concomitant
Hypotension Other Serious 11/1/2006 81 Male 7/13/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Disorder Hospitalization 5/1/2007 62 Male 9/10/2007 Consumer United States
Primary
Concomitant
Vision Blurred 60 Female 7/20/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/7/2007 74 Female 9/6/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Vomiting Other Serious 7/23/2007 24 Male 110 lb 9/15/2007 Physician Germany
Primary
Secondary
Concomitant
Stress Other Serious 11/1/2003 Female 187 lb 9/18/2007 Physician United States
Primary
Concomitant
Alveolitis Other Serious 8/28/2006 Female 9/20/2007 Germany
Primary
Concomitant
Mental Status Changes Hospitalization 8/2/2007 65 Female 236 lb 9/28/2007 Physician United States
Primary
Secondary
Concomitant
Back Pain 75 Male 9/20/2007 Consumer United States
Primary
Concomitant
Flushing 4/26/2007 Female 201 lb 9/20/2007 Consumer United States
Primary
Concomitant
Muscle Spasms 5/14/2007 64 Female 9/20/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 4/1/2007 Male 271 lb 9/28/2007 Physician United States
Primary
Concomitant

Drug Data