Levothyroxine Sodium combined with Metolazone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2005 85 Female 1/26/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 12/8/2005 73 Female 220 lb 1/27/2006 Switzerland
Primary
Concomitant
Vomiting Hospitalization 75 Male 1/30/2006 Physician Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 11/16/2005 Male 2/15/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Life Threatening 12/10/2005 73 Female 2/18/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/7/2006 76 Male 134 lb 4/14/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged 10/20/2005 80 Female 150 lb 4/6/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2002 38 Male 309 lb 10/12/2006 Lawyer United States
Primary
Concomitant
Weight Increased Disability 3/15/2006 93 Male 146 lb 10/31/2006 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Required Intervention 7/11/2006 74 Female 177 lb 7/15/2006 Pharmacist United States
Primary
Concomitant
Tremor 1/1/2006 78 Male 233 lb 10/19/2006 United States
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/3/2007 69 Female 172 lb 3/13/2007 Physician United States
Primary
Concomitant
Wound Secretion Hospitalization 10/26/2004 75 Male 180 lb 3/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 3/12/2007 Female 3/27/2007 Other Health Professional United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/3/2007 69 Female 172 lb 4/25/2007 Consumer United States
Primary
Concomitant
Rash Other Serious Female 200 lb 4/27/2007 Physician United States
Primary
Concomitant
Interacting
Blood Glucose Increased 11/16/2006 59 Female 240 lb 2/6/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 12/26/2006 76 Male 218 lb 7/12/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Disability 4/14/2007 59 Male 243 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/3/2007 69 Female 172 lb 8/7/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/12/2007 Female 273 lb 9/5/2007 Pharmacist United States
Primary
Concomitant
Fall Hospitalization 6/21/2007 65 Male 121 lb 9/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 2/26/2007 Female 198 lb 4/4/2008 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/17/2007 Female 182 lb 4/10/2008 United States
Primary
Concomitant
Cardiac Arrest Death 2/26/2007 Female 198 lb 4/11/2008 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 6/11/2007 65 Male 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/29/2008 74 Male 6/13/2008 Physician Canada
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 1/1/2007 Female 315 lb 7/24/2008 Consumer United States
Primary
Concomitant
Swelling Hospitalization 1/1/2007 Female 315 lb 8/7/2008 Physician United States
Primary
Concomitant
Rash Macular 7/11/2008 Female 8/29/2008 United States
Primary
Concomitant
Swelling Hospitalization 1/1/2007 Female 315 lb 9/4/2008 Physician United States
Primary
Concomitant
Tremor Hospitalization 7/11/2008 Female 170 lb 9/12/2008 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/19/2007 65 Female 240 lb 10/7/2008 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased 3/17/2008 84 Male 152 lb 11/3/2008 Consumer United States
Primary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Tremor Hospitalization 7/11/2008 Female 170 lb 11/10/2008 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/15/2008 79 Female 156 lb 11/9/2008 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 76 Male 11/13/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2006 75 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased 10/20/2008 Female 11/26/2008 United States
Primary
Concomitant
Death Death Male 225 lb 12/23/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 76 Male 218 lb 2/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 1/8/2009 Male 162 lb 3/4/2009 Consumer United States
Primary
Concomitant
Blood Glucose Increased 3/17/2008 84 Male 152 lb 3/5/2009 Consumer United States
Primary
Concomitant
Death Death 2/22/2009 Female 162 lb 3/5/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 66 Male 4/7/2009 United States
Primary
Concomitant
Respiratory Failure Life Threatening 1/1/1999 Female 408 lb 4/15/2009 United States
Primary
Concomitant
Skin Tightness Other Serious 11/1/2005 59 Female 174 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 11/1/2005 59 Female 174 lb 4/20/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/28/2008 66 Male 5/1/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/6/2009 Physician United States
Primary
Concomitant
Vertigo Hospitalization 4/28/2008 65 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/13/2009 Physician United States
Primary
Concomitant
Renal Disorder Hospitalization 4/28/2008 65 Male 7/7/2009 United States
Primary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/14/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 10/26/2004 75 Male 180 lb 8/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tenderness 9/10/2008 Female 8/21/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 6/19/2009 86 Female 8/14/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/2/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 46 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/4/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/3/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 9/15/2009 United States
Primary
Concomitant
Retroperitoneal Haematoma Required Intervention 11/8/2008 72 Female 234 lb 11/21/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 46 Male 9/18/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/22/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 88 Male 179 lb Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 10/10/2009 United States
Primary
Concomitant
Weight Fluctuation Hospitalization 46 Male 10/22/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 78 Female 10/27/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 46 Male 326 lb 11/16/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 11/18/2009 United States
Primary
Concomitant
Swelling Hospitalization 1/1/2007 Female 315 lb 12/1/2009 Physician United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Impaired Self-care Other Serious 6/1/2009 Female 215 lb 12/30/2009 United States
Primary
Concomitant
Death Death Female 1/5/2010 Consumer United States
Primary
Concomitant
Varicose Vein Hospitalization 73 Female 1/12/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 1/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 78 Female 1/22/2010 United States
Primary
Concomitant
Skin Discolouration Other Serious 6/23/2009 Male 300 lb 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 7/12/1999 Female 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 7/12/1999 Female 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 46 Male 326 lb 3/5/2010 Lawyer United States
Primary
Secondary
Concomitant
Palpitations Disability 1/18/2010 Female 155 lb 3/19/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization Female 259 lb 4/13/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 192 lb 4/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea 1/1/2010 66 Male 4/29/2010 Consumer
Primary
Concomitant
Urine Output Decreased Other Serious 10/1/2007 63 Male 193 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 64 Female 5/19/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Tremor Other Serious 10/20/2009 66 Male 300 lb 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 60 Female 6/21/2010
Primary
Secondary
Death Death Male 6/30/2010 Consumer United States
Primary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 64 Female 6/30/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/5/2010 United States
Primary
Secondary
Concomitant
Cardiac Failure Death Female 7/6/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/8/2010 United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Death Male 7/9/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 84 Female 7/16/2010 Lawyer United States
Primary
Concomitant
Vomiting Required Intervention 7/1/2010 67 Male 253 lb 7/14/2010 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/11/2010 63 Female 184 lb 7/21/2010 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Male 7/21/2010 Consumer United States
Primary
Concomitant
Product Substitution Issue Required Intervention 6/14/2010 53 Female 250 lb 7/12/2010 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Male 7/28/2010 Physician United States
Primary
Concomitant
Vision Blurred Required Intervention 60 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 75 Female 7/26/2010 Consumer United States
Primary
Concomitant
Skin Burning Sensation Female 276 lb 8/6/2010 Consumer United States
Primary
Concomitant
Vision Blurred Required Intervention 60 Female 8/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Retching Other Serious 1/19/2010 61 Male 321 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 9/29/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/5/2010 88 Female 11/23/2010 Physician Switzerland
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 1/1/2010 12/22/2010 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2007 63 Male 192 lb 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 7/12/1999 63 Female 2/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 12/18/2010 71 Female 3/30/2011 Physician United States
Primary
Concomitant
Hypertension Other Serious 1/1/2008 84 Female 3/31/2011 Lawyer United States
Primary
Concomitant
Chest Pain Hospitalization 2/1/2011 83 Male 4/21/2011 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious Female 291 lb 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 1/25/2011 73 Female 5/17/2011 Physician United States
Primary
Concomitant
Injury Other Serious Female 291 lb 5/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Uterine Cancer Other Serious Female 249 lb 6/8/2011 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 5/15/2010 80 Female 6/13/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Haemodialysis Hospitalization 5/15/2010 80 Female 6/22/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious 1/4/2001 64 Female 6/22/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death 63 Female 220 lb 6/22/2011 Pharmacist United States
Primary
Concomitant
Anaemia Other Serious 7/1/2006 55 Male 351 lb 6/30/2011 Consumer United States
Primary
Concomitant
Incorrect Storage Of Drug Other Serious 5/1/2011 55 Female 7/8/2011 Other Health Professional United States
Primary
Concomitant
General Physical Health Deterioration Other Serious Female 291 lb 7/12/2011 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 291 lb 7/21/2011 Lawyer United States
Primary
Secondary
Concomitant

Drug Data