Levothyroxine Sodium combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 8/13/2000 Female 1/3/2006 Australia
Primary
Concomitant
Syncope Hospitalization 2/18/2002 Male 1/4/2006 France
Primary
Concomitant
Renal Cyst Hospitalization 7/16/2004 Male 1/4/2006 France
Primary
Concomitant
Weight Increased Hospitalization 11/28/2005 63 Female 194 lb 1/5/2006 Physician France
Primary
Secondary
Concomitant
Toe Amputation Hospitalization 9/1/2005 Female 220 lb 1/13/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 1/17/2006 United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 11/1/2005 81 Female 2/15/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/23/2005 57 Female 184 lb 1/20/2006 Consumer United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 1/1/2005 76 Female 170 lb 3/10/2006 United States
Primary
Concomitant
Weight Fluctuation Other Serious 61 Female 202 lb 3/15/2006 Consumer United States
Primary
Secondary
Concomitant
Nausea 10/6/2005 63 Female 220 lb 1/20/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 9/28/2005 42 Female 328 lb 12/14/2005 Other Health Professional United States
Primary
Concomitant
Stress Hospitalization 1/11/2006 68 Female 153 lb 3/20/2006 Other Health Professional Canada
Primary
Concomitant
Nerve Compression Hospitalization 3/1/2006 Female 258 lb 3/30/2006 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/1/2005 49 Female 214 lb 3/27/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Weight Decreased 12/1/2005 63 Male 212 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 10/1/1959 14 Female 202 lb 4/5/2006 United States
Primary
Secondary
Concomitant
Panic Disorder Hospitalization 1/1/2002 37 Female 214 lb 4/17/2006 Lawyer Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 58 Female 168 lb 4/10/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 4/2/2006 Female 331 lb 5/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus 12/1/2005 50 Female 112 lb 2/20/2006 United States
Primary
Concomitant
Infection Hospitalization 1/11/2006 68 Female 153 lb 5/3/2006 Other Health Professional Canada
Primary
Concomitant
Tremor Other Serious 74 Male 291 lb 5/11/2006 United States
Primary
Secondary
Concomitant
Syncope Life Threatening 4/2/2006 Female 331 lb 5/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Death 78 Female 5/9/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 3/7/2006 74 Male 291 lb 5/19/2006 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/24/2006 66 Male 5/11/2006 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 224 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/24/2006 66 Male 5/22/2006 Physician France
Primary
Secondary
Concomitant
Dyspnoea 1/25/2006 63 Female 188 lb 4/6/2006 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization Female 266 lb 6/1/2006 Physician United States
Primary
Concomitant
Precancerous Cells Present Other Serious 10/1/2005 57 Female 5/25/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/7/2006 74 Male 291 lb 5/24/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2006 88 Male 6/12/2006 United States
Primary
Concomitant
Resuscitation Hospitalization 11/5/2005 79 Male 6/5/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Life Threatening 1/30/2006 78 Female 6/14/2006 Canada
Primary
Secondary
Concomitant
Vomiting Required Intervention 3/1/2006 47 Female 6/15/2006 Germany
Primary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 1/30/2006 78 Female 6/19/2006 Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/15/2006 69 Female 6/22/2006 Physician Hong Kong
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/24/2006 64 Female 190 lb 6/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased 6/2/2005 43 Female 6/22/2006 Other Health Professional Canada
Primary
Concomitant
Weight Decreased 1/1/2006 60 Female 235 lb 4/17/2006 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Death 4/19/2006 Female 325 lb 7/7/2006 Physician Canada
Primary
Concomitant
Angioneurotic Oedema Life Threatening 6/9/2006 72 Female 144 lb 6/14/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 5/15/2006 69 Female 7/14/2006 Physician Hong Kong
Primary
Concomitant
Weight Decreased 10/11/2005 52 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 5/1/2005 68 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Leukopenia Required Intervention 4/10/2006 64 Female 5/22/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/24/2006 64 Female 190 lb 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/15/2006 55 Male 350 lb 7/24/2006 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 6/6/2006 60 Male 180 lb 8/1/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/8/2006 58 Male 285 lb 8/7/2006 Pharmacist United States
Primary
Concomitant
Pruritus Life Threatening 6/4/2006 55 Male 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 31 Male 220 lb 4/19/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 71 Female 8/18/2006 Denmark
Primary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 9/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/8/2006 59 Male 225 lb 9/26/2006 Physician United States
Primary
Secondary
Concomitant
Tongue Coated Life Threatening 9/24/2006 76 Female 154 lb 10/7/2006 Physician Canada
Primary
Concomitant
Tongue Coated Life Threatening 9/27/2006 76 Female 154 lb 10/10/2006 Physician Canada
Primary
Concomitant
Vision Blurred Disability 8/1/2006 71 Female 115 lb 10/24/2006 Physician United States
Primary
Concomitant
Parathyroid Gland Enlargement Hospitalization 10/20/2006 65 Female 174 lb 11/1/2006 Consumer United States
Primary
Concomitant
Blood Sodium Decreased Other Serious 68 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Required Intervention 9/1/2006 60 Female 182 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/1/2006 Female 195 lb 11/22/2006 Physician United States
Primary
Concomitant
Megakaryocytes Increased Other Serious 10/16/2006 55 Female 11/20/2006 Other Health Professional Denmark
Primary
Concomitant
Weight Decreased Other Serious 54 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vision Blurred Other Serious 1/1/2003 56 Female 142 lb 12/4/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/8/2006 59 Male 225 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Throat Tightness 1/9/2006 Female 12/20/2006 Consumer United States
Primary
Concomitant
Nausea Death 12/31/2006 66 Male 120 lb 1/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Congestion Hospitalization 11/29/2006 Female 254 lb 1/16/2007 Physician Portugal
Primary
Concomitant
Babesiosis Hospitalization 77 Female 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/13/2007 52 Female 270 lb 2/9/2007 Physician United States
Primary
Concomitant
Somnolence Other Serious Female 200 lb 3/21/2007 Pharmacist United States
Primary
Concomitant
Wound Secretion Other Serious 12/1/2006 Female 173 lb 3/22/2007 Physician United States
Primary
Concomitant
Low Density Lipoprotein Decreased Other Serious 62 Male 11/28/2006 United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 182 lb 3/29/2007 Pharmacist United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/20/2007 64 Male 163 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 3/17/2007 70 Female 4/11/2007 Consumer Russian Federation
Primary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 3/13/2007 21 Male 7/5/2007 Physician United States
Primary
Concomitant
Bipolar I Disorder Hospitalization 6/8/2007 56 Female 234 lb 7/5/2007
Primary
Concomitant
Arthralgia Disability 6/1/2007 71 Female 224 lb 7/10/2007 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Chronic Hospitalization 4/23/2007 57 Female 8/16/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Nausea Hospitalization 8/9/2007 Female 174 lb 8/16/2007 Consumer United States
Primary
Concomitant
Optic Neuritis Other Serious 7/6/2007 51 Female 197 lb 9/4/2007 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased 6/10/2007 75 Female 152 lb 7/11/2007 Consumer United States
Primary
Concomitant
Lymphoma Other Serious 6/1/2006 Female 227 lb 9/21/2007 United States
Primary
Concomitant
Peritoneal Haemorrhage Hospitalization 7/24/2007 Male 9/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 Female 192 lb 9/24/2007 Consumer United States
Primary
Concomitant
Transaminases Increased Other Serious 73 Female 9/24/2007 Pharmacist United States
Primary
Concomitant
Interacting
Myalgia 4/15/2007 54 Female 185 lb 8/16/2007 Physician United States
Primary
Concomitant
Rash 5/1/2007 61 Male 9/20/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 Female 10/18/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution 55 Female 10/23/2007 Consumer United States
Primary
Concomitant
Somnolence 8/23/2007 76 Female 10/25/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Disorder Hospitalization 2/1/2007 Female 10/26/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Other Serious 10/7/2007 58 Female 11/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 10/14/2005 52 Female 11/5/2007 Other Health Professional Latvia
Primary
Secondary
Concomitant
Ischaemic Stroke Life Threatening Female 11/6/2007 Physician United Kingdom
Primary
Concomitant
Hepatitis Other Serious 9/24/2007 69 Female 172 lb 11/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hepatitis Other Serious 9/24/2007 69 Female 172 lb 11/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 78 Female 12/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 9/1/2007 Female 1/17/2008 Consumer United States
Primary
Concomitant
Skin Ulcer Life Threatening 4/2/2006 Female 331 lb 2/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred 7/16/2007 53 Female 196 lb 2/15/2008 Other Health Professional United States
Primary
Concomitant
Arthralgia 9/28/2007 40 Female 2/15/2008 United States
Primary
Concomitant
Pseudomonas Infection Disability 11/1/2005 Female 194 lb 3/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 61 Female 3/13/2008 Spain
Primary
Secondary
Pancreatitis Acute Hospitalization 2/1/2008 Female 274 lb 3/12/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 61 Female 3/14/2008 Physician Spain
Primary
Secondary
Concomitant
Drug Ineffective 11/1/2007 Female 180 lb 3/14/2008 Consumer United States
Primary
Concomitant
Pain In Extremity 8/19/2007 Female 150 lb 3/14/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 12/1/2007 Female 3/14/2008 United States
Primary
Concomitant
Road Traffic Accident 1/11/2008 Female 275 lb 3/15/2008 United States
Primary
Concomitant
Accidental Exposure 1/24/2008 Female 3/15/2008 Consumer United States
Primary
Concomitant
Mental Impairment 2/16/2008 3/15/2008 United States
Primary
Concomitant
Renal Failure Acute Other Serious 61 Female 3/18/2008 Other Health Professional United States
Primary
Secondary
Peripheral Vascular Disorder Other Serious 3/1/2008 Male 265 lb 3/24/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2006 Female 3/19/2008 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 1/6/2008 62 Male 3/27/2008 Physician Spain
Primary
Concomitant
Muscular Weakness Disability 9/1/2007 75 Male 258 lb 5/14/2008 Physician United States
Primary
Concomitant
Uterine Cervix Stenosis Other Serious 11/1/2007 60 Female 6/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 50 Female 6/13/2008 Physician United States
Primary
Secondary
Concomitant
Peripheral Vascular Disorder 8/1/2005 Female 198 lb 6/5/2008 Physician United States
Primary
Concomitant
Shock Life Threatening 9/1/2007 Male 6/13/2008 Physician France
Primary
Concomitant
Pharyngitis Hospitalization 5/1/2007 Female 6/17/2008 Physician Germany
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2006 45 Male 6/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 50 Female 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Metastases To Breast Other Serious 3/1/2008 Female 6/19/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 1/1/2008 67 Female 174 lb 6/19/2008 United States
Primary
Concomitant
Renal Neoplasm Other Serious 3/12/2008 Female 6/19/2008 United Kingdom
Primary
Concomitant
Cervix Carcinoma Other Serious Female 204 lb 6/20/2008 Consumer United Kingdom
Primary
Concomitant
Syncope Hospitalization 6/2/2008 Female 157 lb 6/20/2008 Physician Greece
Primary
Concomitant
Sensory Disturbance Other Serious 3/8/2008 Female 262 lb 6/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 227 lb 6/13/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/29/2008 71 Female 7/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/29/2008 71 Female 7/7/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/10/2008 67 Female 7/14/2008 Physician France
Primary
Secondary
Concomitant
Cervical Dysplasia Hospitalization 5/31/2008 Female 204 lb 7/14/2008 Consumer United Kingdom
Primary
Concomitant
Nausea 52 Female 7/15/2008 Consumer United States
Primary
Concomitant
Oedema Other Serious 1/1/2008 Female 135 lb 7/15/2008 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 8/1/2007 Female 7/9/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 153 lb 7/16/2008 United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 Male 7/16/2008 Consumer United States
Primary
Concomitant
Interacting
Syncope Other Serious 9/1/2007 Female 7/16/2008 Physician United States
Primary
Concomitant

Drug Data