Levothyroxine Sodium combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Eye Pain Hospitalization 12/23/1999 Female 1/3/2006 New Zealand
Primary
Concomitant
Syncope Hospitalization 9/27/2000 Female 1/3/2006 France
Primary
Concomitant
Vertigo Hospitalization 11/16/2002 Male 1/4/2006 France
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Tachycardia Other Serious 2/12/2006 72 Female 161 lb 2/28/2006 Physician Germany
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Lactic Acidosis Hospitalization 64 Male 1/22/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/1/2007 45 Female 4/26/2007 United States
Primary
Concomitant
Overdose 11/16/2006 56 Female 210 lb 2/16/2007 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 45 Female 188 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/4/2006 66 Female 165 lb 8/14/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Pharmacist Germany
Primary
Secondary
Suicide Attempt Other Serious 7/6/2007 58 Female 8/6/2007 Physician Germany
Primary
Secondary
Vitamin B12 Deficiency 48 Female 190 lb 9/18/2007 United States
Primary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/19/2007 United Kingdom
Primary
Concomitant
Haemorrhage Hospitalization 7/18/2007 60 Male 9/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/9/2007 77 Female 282 lb 10/24/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Disability 3/1/2006 Male 10/24/2007 United Kingdom
Primary
Concomitant
Urticaria Disability 2/7/2006 83 11/1/2007 United Kingdom
Primary
Concomitant
Uterine Neoplasm Hospitalization 6/1/2007 47 Female 245 lb 11/9/2007 Consumer United States
Primary
Concomitant
Somnolence 7/31/2007 76 Female 11/19/2007 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/19/2006 73 Male 280 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Hospitalization 12/1/2007 Female 196 lb 1/21/2008 Consumer United States
Primary
Concomitant
Hypertension Other Serious 6/1/2007 Female 231 lb 2/8/2008 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia 1/1/2004 64 Female 145 lb 2/20/2008 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 11/23/2007 68 Male 218 lb 2/21/2008 United Kingdom
Primary
Concomitant
Visual Disturbance Disability 10/1/2007 57 Female 315 lb 3/3/2008 Consumer United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection 1/1/2007 61 Female 115 lb 2/15/2008 Physician United States
Primary
Concomitant
Pharyngolaryngeal Pain 1/26/2008 Female 201 lb 3/15/2008 Consumer United States
Primary
Concomitant
Fatigue Other Serious 50 Female 268 lb 3/28/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 55 Female 3/28/2008
Primary
Concomitant
Vomiting Required Intervention 78 Female 4/10/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 11/1/2007 Male 6/9/2008
Primary
Concomitant
Vomiting Hospitalization 50 Female 6/27/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 7/28/2008 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 3/1/2008 32 Female 8/22/2008 Consumer Switzerland
Primary
Concomitant
Pyrexia Hospitalization 5/9/2008 Female 8/25/2008 Physician Germany
Primary
Concomitant
Visual Impairment Hospitalization 3/1/2008 32 Female 8/26/2008 Consumer Switzerland
Primary
Concomitant
Rash Generalised 11/28/2007 Male 208 lb 8/27/2008 Consumer United States
Primary
Secondary
Concomitant
Urticaria 7/16/2008 Female 8/29/2008 United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/30/2008 69 Female 9/15/2008 Physician France
Primary
Concomitant
Urinary Tract Infection Death 56 Male 10/6/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Rash Macular Hospitalization 8/1/2008 43 Male 10/8/2008 Physician United States
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 67 Female 10/17/2008 Other Health Professional United States
Primary
Concomitant
Tachypnoea Life Threatening 6/23/2008 Male 259 lb 10/17/2008 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 8/22/2008 Male 10/20/2008 Consumer Germany
Primary
Secondary
Concomitant
Thrombosis Hospitalization 7/1/2007 Female 229 lb 10/14/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2008 Male 10/17/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2008 Male 212 lb 10/16/2008 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/16/2008 Male 225 lb 10/21/2008 United Kingdom
Primary
Concomitant
Astrocytoma Other Serious 1/8/2008 Male 204 lb 10/21/2008 Physician Canada
Primary
Concomitant
Medication Error 9/19/2008 Male 211 lb 10/6/2008 Pharmacist United States
Primary
Concomitant
Tooth Abscess Life Threatening 9/30/2008 72 Male 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 8/22/2008 Male 10/27/2008 Consumer Germany
Primary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Spina Bifida Congenital Anomaly 12/1/2007 Female 12/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Gastric Banding Other Serious 56 Female 500 lb 1/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Female 2/5/2009 United States
Primary
Concomitant
Syncope Other Serious 1/19/2009 Female 170 lb 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Flushing Male 2/24/2009 United States
Primary
Secondary
Concomitant
Plantar Fasciitis 6/1/2007 Female 220 lb 3/14/2009 United States
Primary
Concomitant
Gastric Banding Other Serious 56 Female 500 lb 4/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Priapism Hospitalization 5/1/2009 65 Male 156 lb 5/15/2009 Pharmacist United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/15/2008 65 Male 5/15/2009 United States
Primary
Concomitant
Weight Decreased Life Threatening 6/24/2008 59 Female 6/5/2009 Physician Sweden
Primary
Concomitant
Rectal Cancer Other Serious 3/13/2009 Female 146 lb 6/8/2009 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Female 6/15/2009 Consumer United States
Primary
Concomitant
Multiple Drug Overdose Hospitalization 60 Male 6/15/2009 United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 12/1/2008 61 Female 6/24/2009 Other Health Professional France
Primary
Concomitant
Rash Pruritic Hospitalization 6/20/2009 77 Female 7/1/2009 Consumer United States
Primary
Concomitant
Feeling Hot Female 8/22/2009 United States
Primary
Concomitant
Purpura Other Serious 7/7/2009 75 Male 9/9/2009 Other Health Professional
Primary
Secondary
Concomitant
Vasculitis Other Serious 7/7/2009 75 Male 9/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Knee Arthroplasty Other Serious 8/10/2009 Male 194 lb 10/2/2009 Physician United States
Primary
Concomitant
Pustular Psoriasis Other Serious 4/1/2009 Female 198 lb 10/15/2009 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2007 65 Male 211 lb 10/15/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2009 Female 280 lb 10/12/2009 Consumer United States
Primary
Concomitant
Drug Ineffective 9/7/2009 Female 10/16/2009 Consumer
Primary
Concomitant
Irritable Bowel Syndrome 3/1/2009 Female 10/16/2009 Consumer
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 76 Female 10/19/2009 Pharmacist United States
Primary
Concomitant
Knee Arthroplasty Other Serious 8/10/2009 Male 194 lb 11/13/2009 Physician United States
Primary
Concomitant
Hypoglycaemia Life Threatening 6/3/2008 61 Male 231 lb 11/23/2009 Physician Belgium
Primary
Concomitant
Asthma Other Serious 11/12/2009 Female 270 lb 12/1/2009 Physician United States
Primary
Concomitant
Nausea Hospitalization 12/1/2007 Female 196 lb 11/30/2009 Consumer United States
Primary
Concomitant
Hypoglycaemia Life Threatening 6/3/2008 61 Male 231 lb 12/9/2009 Physician Belgium
Primary
Concomitant
Cytolytic Hepatitis Life Threatening 8/1/2009 59 Male 12/17/2009 Physician Belgium
Primary
Concomitant
Somnambulism Death 11/1/2009 48 Male 12/14/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 12/30/2009 United States
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased 5/26/2009 58 Female 1/4/2010 Consumer United States
Primary
Concomitant
Product Quality Issue 9/14/2009 62 Female 1/4/2010 Consumer United States
Primary
Concomitant
Vomiting 10/25/2009 72 Female 1/4/2010 Consumer United States
Primary
Concomitant
Thyroxine Decreased Other Serious 10/1/2009 49 Male 256 lb 1/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thyroxine Free Decreased Other Serious 10/1/2009 49 Male 256 lb 1/12/2010 Consumer United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/6/2010 46 Male 476 lb 1/8/2010 Pharmacist United States
Primary
Concomitant
Wheezing Hospitalization 12/14/2009 Female 1/19/2010 United States
Primary
Concomitant
Syncope Other Serious 1/19/2009 Female 170 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain 1/1/2008 Male 330 lb 1/30/2010 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious Male 2/3/2010 Lawyer United States
Primary
Concomitant
Catheterisation Cardiac Hospitalization Female 235 lb 2/18/2010 Consumer United States
Primary
Concomitant
Social Avoidant Behaviour 1/1/2007 54 Female 2/26/2010 Consumer United States
Primary
Concomitant
Rib Fracture Hospitalization 7/18/2007 76 Female 238 lb 3/2/2010 Physician United Kingdom
Primary
Concomitant
Pulse Absent Hospitalization 2/14/2010 29 Male 250 lb 3/2/2010 Consumer United States
Primary
Concomitant
Swollen Tongue Life Threatening 12/29/2009 Female 3/9/2010 Pharmacist United States
Primary
Secondary
Concomitant
Tracheal Stenosis Other Serious 12/10/2007 Female 185 lb 3/15/2010 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 2/25/2010 84 Female 3/16/2010 Consumer United States
Primary
Concomitant
Sneezing 11/1/2009 Female 140 lb 3/16/2010 Consumer United States
Primary
Concomitant
Tracheal Stenosis Other Serious 12/10/2007 Female 185 lb 3/16/2010 Physician United States
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/19/2010 Physician Argentina
Primary
Concomitant
Wheezing Other Serious 11/12/2009 Female 270 lb 3/22/2010 United States
Primary
Concomitant
Femur Fracture Hospitalization 3/17/2010 65 Male 175 lb 3/26/2010 United States
Primary
Concomitant
Embolic Stroke Hospitalization 79 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/26/2010 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/29/2010 Physician Argentina
Primary
Concomitant
Ventricular Septal Defect Other Serious 11/5/2009 Male 7 lb 4/1/2010 Consumer United States
Primary
Secondary
Pulmonary Embolism Life Threatening 3/29/2010 56 Male 181 lb 4/6/2010 Physician Turkey
Primary
Secondary
Concomitant
Sudden Death Life Threatening 3/29/2010 56 Male 181 lb 4/15/2010 Physician Turkey
Primary
Secondary
Concomitant
Ventricular Septal Defect Congenital Anomaly 11/5/2009 Male 7 lb 5/7/2010 Physician United States
Primary
Secondary
Sudden Death Life Threatening 3/29/2010 56 Male 181 lb 5/7/2010 Physician Turkey
Primary
Secondary
Concomitant
Rash Macular 3/1/2010 79 Male 185 lb 5/13/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/11/2010 58 Male 240 lb 5/13/2010 Other Health Professional United States
Primary
Concomitant
Torsade De Pointes Life Threatening 64 Female 5/19/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Urticaria Life Threatening 3/10/2010 43 Female 5/19/2010 Physician Germany
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/9/2010 50 Male 261 lb 5/18/2010 United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2001 65 Female 180 lb 5/26/2010 Consumer United States
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 2/1/2010 35 Male 300 lb 5/26/2010 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 10/20/2009 66 Male 300 lb 5/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis 4/4/2010 74 Female 220 lb 5/27/2010 Consumer United States
Primary
Secondary
Concomitant
Thought Blocking Other Serious 1/1/2007 43 Female 182 lb 5/28/2010 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/14/2009 66 Female 6/24/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 4/9/2010 50 Male 261 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Pruritus Generalised 6/24/2008 41 Female 180 lb 7/22/2010 Consumer United States
Primary
Concomitant
Oropharyngeal Pain Other Serious Female 244 lb 7/23/2010 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 49 Male 323 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/22/2010 65 Female 7/30/2010 Other Health Professional Denmark
Primary
Concomitant
Intentional Drug Misuse Death 2/10/2010 76 Female 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 219 lb 9/10/2010 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 1/15/2010 74 Male 225 lb 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 46 Male 167 lb 9/10/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2009 75 Female 143 lb 9/14/2010 Other Health Professional France
Primary
Secondary
Weight Decreased Other Serious 1/1/2010 81 Female 163 lb 9/17/2010 Consumer United States
Primary
Secondary
Concomitant
Pleuropericarditis Hospitalization 3/16/2010 56 Female 9/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 2/10/2010 76 Female 9/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/29/2010 11/23/2010 Physician Belgium
Primary
Concomitant

Drug Data