Levothyroxine Sodium combined with Marcumar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancreatitis Acute Hospitalization 10/28/2004 64 Female 174 lb 2/8/2006 Other Health Professional Belgium
Primary
Concomitant
Tachycardia Other Serious 2/12/2006 72 Female 161 lb 2/28/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/1/2004 56 Female 4/5/2006 Physician Germany
Primary
Concomitant
Vestibular Disorder Hospitalization 12/1/2004 56 Female 6/13/2006 Physician Germany
Primary
Concomitant
Heart Rate Increased Other Serious Female 132 lb 6/22/2006 Physician Germany
Primary
Concomitant
Oedema Hospitalization 1/31/2006 37 Female 8/17/2006 Germany
Primary
Concomitant
Pulmonary Hypertension Hospitalization 1/31/2006 37 Female 9/6/2006 Physician Germany
Primary
Concomitant
Sepsis Other Serious 11/4/2006 79 Female 157 lb 12/18/2006 Physician Germany
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2006 Male 175 lb 3/2/2007 Physician Belgium
Primary
Concomitant
Scleroderma Hospitalization 3/5/2007 61 Female 200 lb 6/12/2007 Physician Germany
Primary
Concomitant
Laboratory Test Abnormal Life Threatening 6/14/2007 82 Female 6/22/2007 Physician Belgium
Primary
Concomitant
Interacting
Pneumocystis Jiroveci Infection Death 66 Female 132 lb 7/5/2007 Physician Germany
Primary
Concomitant
Drug Interaction Life Threatening 4/1/2006 Female 123 lb 7/9/2007 Physician Belgium
Primary
Concomitant
Interacting
Drug Interaction Life Threatening 4/1/2006 Female 123 lb 7/12/2007 Physician Belgium
Primary
Concomitant
Interacting
Hepatitis Other Serious 6/1/2007 Male 7/20/2007 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/6/2007 64 Female 181 lb 8/16/2007 Physician Belgium
Primary
Concomitant
Transaminases Increased Other Serious 5/1/2007 76 Male 8/22/2007 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/5/2007 64 Female 181 lb 9/8/2007 Physician Belgium
Primary
Concomitant
Renal Failure Acute Hospitalization 8/5/2007 64 Female 181 lb 9/21/2007 Physician Belgium
Primary
Concomitant
Paraesthesia Hospitalization 10/1/2007 Female 11/1/2007 Physician Germany
Primary
Concomitant
Tachycardia Hospitalization 10/18/2007 50 Female 141 lb 11/8/2007 Physician Germany
Primary
Concomitant
Paraesthesia Other Serious 10/1/2007 Female 11/21/2007 Physician Germany
Primary
Concomitant
Parkinson's Disease Other Serious 1/1/2007 66 Male 3/25/2008 Physician France
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 1/1/2007 66 Male 3/25/2008 Physician France
Primary
Secondary
Concomitant
Malaise Other Serious Male 179 lb 4/11/2008 Physician Germany
Primary
Secondary
Concomitant
Tremor Other Serious 4/1/2007 66 Male 165 lb 4/2/2008 Physician France
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 4/1/2007 66 Male 165 lb 4/2/2008 Physician France
Primary
Secondary
Concomitant
Spinal Disorder Other Serious Male 179 lb 4/22/2008 Physician Germany
Primary
Secondary
Concomitant
Systemic Sclerosis Hospitalization 3/5/2007 Female 200 lb 7/4/2008 Physician Germany
Primary
Concomitant
Ischaemic Cerebral Infarction Hospitalization 3/25/2008 82 Female 7/10/2008 Physician Austria
Primary
Concomitant
Renal Failure Other Serious 10/11/2008 Male 11/6/2008 Physician Germany
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 10/3/2008 55 Male 11/7/2008 Other Health Professional France
Primary
Interacting
Thrombocytopenia Other Serious 8/19/2008 Female 11/30/2008 Consumer Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 12/10/2008 Consumer Germany
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 4/28/2008 52 Female 12/22/2008 Other Health Professional Germany
Primary
Concomitant
Pulmonary Congestion Hospitalization 11/9/2008 72 Male 12/30/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 1/20/2009 Consumer Germany
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 4/28/2008 52 Female 1/21/2009 Other Health Professional Germany
Primary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 Female 2/6/2009 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/19/2008 Female 2/25/2009 Consumer Germany
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 11/14/2008 61 5/12/2009 Physician Germany
Primary
Secondary
Concomitant
Drug Intolerance Hospitalization 6/14/2009 25 7/1/2009 Physician Germany
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 3/1/2009 87 Female 7/1/2009 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/23/2009 87 Female 7/2/2009 Physician Germany
Primary
Concomitant
Paraesthesia Hospitalization 6/11/2009 Female 187 lb 7/16/2009 Physician Switzerland
Primary
Concomitant
Paraesthesia Hospitalization 6/11/2009 Female 187 lb 7/21/2009 Physician Switzerland
Primary
Concomitant
Off Label Use Hospitalization 2/23/2009 87 Female 7/27/2009 Physician Germany
Primary
Concomitant
Tachyarrhythmia Other Serious 8/1/2009 66 Female 165 lb 10/22/2009 Physician Germany
Primary
Concomitant
Tachyarrhythmia Other Serious 8/1/2009 66 Female 165 lb 10/29/2009 Physician Germany
Primary
Concomitant
Drug Intolerance Hospitalization 6/14/2009 25 Male 11/9/2009 Physician Germany
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Other Serious 10/19/2009 Male 309 lb 11/9/2009 Physician Germany
Primary
Secondary
Concomitant
Gastritis Other Serious 10/19/2009 Male 309 lb 11/12/2009 Physician Germany
Primary
Secondary
Concomitant
Gastritis Other Serious 10/19/2009 Male 309 lb 11/12/2009 Physician Germany
Primary
Secondary
Concomitant
Eye Haemorrhage Other Serious 81 Male 198 lb 12/10/2009 Physician Germany
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 12/17/2008 78 Male 2/4/2010 Other Health Professional Germany
Primary
Concomitant
Thrombocytopenia Life Threatening 1/1/2010 Male 2/22/2010 Physician Germany
Primary
Concomitant
Muscle Spasms Life Threatening 12/1/2009 70 Male 192 lb 2/23/2010 Germany
Primary
Concomitant
Respiratory Arrest Life Threatening 2/26/2010 70 Female 163 lb 3/30/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/9/2010 84 Female 137 lb 4/19/2010 Physician Germany
Primary
Concomitant
Bronchial Hyperreactivity Other Serious 11/1/2009 76 Male 4/12/2010 Germany
Primary
Concomitant
Hepatotoxicity Hospitalization 3/1/2010 43 Female 4/20/2010 Other Health Professional Germany
Primary
Concomitant
Hepatorenal Syndrome Other Serious 3/9/2010 84 Female 4/28/2010 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Death 3/9/2010 84 Female 137 lb 4/29/2010 Other Health Professional Germany
Primary
Concomitant
Prothrombin Time Abnormal Hospitalization 1/1/2010 Female 5/3/2010 Physician Germany
Primary
Concomitant
Interacting
Liver Injury Hospitalization 3/1/2010 43 Female 4/30/2010 Physician Germany
Primary
Concomitant
Intestinal Haemorrhage Hospitalization 10/1/2009 68 Female 5/12/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Polyp Hospitalization Female 5/14/2010 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/1/2010 71 Female 165 lb 5/14/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/27/2010 79 Male 198 lb 6/1/2010 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious Female 64 lb 6/3/2010 Other Health Professional Austria
Primary
Concomitant
Weight Decreased Other Serious Female 64 lb 6/4/2010 Other Health Professional Austria
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/1/2010 71 Female 165 lb 6/4/2010 Physician Germany
Primary
Secondary
Concomitant
Eye Haemorrhage Other Serious 3/1/2010 59 Female 6/2/2010 Germany
Primary
Concomitant
Microcytic Anaemia 70 Male 6/3/2010 Germany
Primary
Concomitant
Mixed Liver Injury Hospitalization 4/22/2010 73 Female 132 lb 6/15/2010 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Hepatorenal Syndrome Other Serious 3/9/2010 84 Female 6/18/2010 Other Health Professional France
Primary
Concomitant
Varices Oesophageal Hospitalization 3/1/2010 43 Female 7/12/2010 Other Health Professional Germany
Primary
Concomitant
Yellow Skin Other Serious Female 7/27/2010 Physician Austria
Primary
Concomitant
Muscle Spasms Life Threatening 1/1/2009 70 Male 192 lb 8/27/2010 Physician Germany
Primary
Concomitant
Muscle Spasms Life Threatening 1/1/2009 70 Male 192 lb 9/1/2010 Physician Germany
Primary
Concomitant
Varices Oesophageal Other Serious 3/1/2010 43 Female 121 lb 9/8/2010 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 198 lb 9/27/2010 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 207 lb 10/7/2010 Physician Germany
Primary
Secondary
Concomitant
Urosepsis Life Threatening 10/14/2009 74 Female 123 lb 11/8/2010 Physician Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 11/14/2008 61 Female 223 lb 12/14/2010 Physician Germany
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 9/14/2010 73 Female 205 lb 12/16/2010 Physician United States
Primary
Concomitant
Interacting
Death Death 1/1/2010 49 Male 295 lb 1/13/2011 Other Health Professional Germany
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 76 Female 2/10/2011 Physician Germany
Primary
Concomitant
Blood Creatinine Increased Hospitalization 8/27/2010 56 Male 254 lb 2/15/2011 Physician Germany
Primary
Concomitant
Oedema Mucosal Other Serious 1/1/2011 70 Female 2/28/2011 Pharmacist Germany
Primary
Concomitant
Cor Pulmonale Death 68 Female 3/21/2011 Physician Germany
Primary
Concomitant
Abdominal Pain Hospitalization 1/1/2011 76 Female 4/13/2011 Physician Switzerland
Primary
Secondary
Concomitant
Cor Pulmonale Death 68 Female 5/11/2011 Physician Germany
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2011 76 Female 5/6/2011 Physician Switzerland
Primary
Secondary
Concomitant
Pneumonia Primary Atypical Hospitalization 1/1/2011 92 Male 5/23/2011 Pharmacist Germany
Primary
Concomitant
Drug Effect Increased Life Threatening 11/8/2010 80 Female 143 lb 5/26/2011 Other Health Professional Germany
Primary
Concomitant
Interacting
Sleep Disorder Other Serious 2/1/2010 Male 6/14/2011 Consumer Germany
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 11/8/2010 80 Female 6/7/2011 Physician Germany
Primary
Secondary
Concomitant
Lipase Increased Other Serious 3/19/2011 23 Male 6/20/2011 Physician Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 11/14/2008 61 Female 223 lb 6/23/2011 Physician Germany
Primary
Concomitant
Joint Effusion Other Serious 9/1/2010 62 Female 163 lb 6/27/2011 Physician Germany
Primary
Concomitant
Hypotension Hospitalization 5/17/2011 50 Male 6/23/2011 Physician Germany
Primary
Secondary
Somnolence Hospitalization 5/17/2011 50 Male 7/5/2011 Physician Germany
Primary
Secondary
Drug Effect Increased Life Threatening 11/8/2010 80 Female 143 lb 8/12/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 5/4/2011 76 Male 194 lb 8/19/2011 Physician Germany
Primary
Concomitant
Coagulation Time Abnormal Other Serious Male 198 lb 9/2/2011 Physician Germany
Primary
Secondary
Concomitant
Headache Other Serious 8/6/2011 24 Female 146 lb 9/9/2011 Physician Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 12/2/2010 61 Male 291 lb 9/7/2011 Physician Germany
Primary
Concomitant
Concomitant Disease Progression Life Threatening 6/27/2011 58 Female 159 lb 9/23/2011 Physician Germany
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 5/31/2011 89 Female 148 lb 9/26/2011 Physician Germany
Primary
Concomitant
Coagulation Time Abnormal Other Serious Male 198 lb 9/30/2011 Physician Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 10/22/2010 75 Female 10/5/2011 Physician Germany
Primary
Concomitant
Renal Impairment Other Serious 4/4/2011 76 Male 216 lb 10/7/2011 Physician Germany
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 2/18/2009 80 Female 220 lb 10/10/2011 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization Female 10/12/2011 Consumer Germany
Primary
Concomitant
Hypomagnesaemia Hospitalization 2/18/2009 80 Female 220 lb 10/13/2011 Physician Netherlands
Primary
Secondary
Concomitant
Constipation Hospitalization 9/18/2011 52 Female 201 lb 10/18/2011 Physician Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2011 Female 10/31/2011 Physician Germany
Primary
Secondary
Concomitant
Mastitis Other Serious 8/15/2011 66 Male 150 lb 11/25/2011 Pharmacist Germany
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 10/1/2011 78 Male 159 lb 11/28/2011 Physician Germany
Primary
Concomitant
Dysgeusia Other Serious 10/1/2011 78 Male 159 lb 11/28/2011 Physician Germany
Primary
Concomitant
Polycythaemia Other Serious 1/1/2009 67 Male 11/30/2011 Consumer Germany
Primary
Concomitant
Oedema Peripheral Hospitalization 5/28/2011 Female 216 lb 11/29/2011 Physician Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2011 Female 216 lb 12/1/2011 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 8/1/2011 65 Female 205 lb 12/5/2011 Physician Germany
Primary
Concomitant
Ascites Other Serious 1/1/2011 75 Female 12/12/2011 Physician Germany
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 4/30/2011 82 Female 12/15/2011 Other Health Professional Germany
Primary
Concomitant
Atrial Fibrillation Other Serious 1/4/2011 61 Female 203 lb 12/16/2011 Physician Germany
Primary
Secondary
Concomitant
Rectal Cancer Metastatic Death 3/1/2011 61 Female 203 lb 12/26/2011 Physician Germany
Primary
Secondary
Concomitant
Hallucination Other Serious 6/10/2011 85 Female 168 lb 12/28/2011 Pharmacist Germany
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2011 65 Female 205 lb 1/16/2012 Physician Germany
Primary
Concomitant
Retinal Artery Occlusion Hospitalization 12/23/2011 72 Male 1/17/2012 Physician Germany
Primary
Concomitant
Sphincter Of Oddi Dysfunction Hospitalization 4/30/2011 82 Female 1/24/2012 Physician Germany
Primary
Concomitant
Venous Thrombosis Other Serious 10/18/2011 1/26/2012 Physician Germany
Primary
Secondary
Concomitant
Concomitant Disease Progression Life Threatening 6/27/2011 58 Female 159 lb 1/30/2012 Physician Germany
Primary
Secondary
Concomitant
Retinal Artery Occlusion Other Serious 10/22/2010 75 Female 2/17/2012 Physician Germany
Primary
Concomitant
Gastroenteritis Norovirus Hospitalization 11/14/2011 76 Female 139 lb 2/22/2012 Consumer Germany
Primary
Concomitant
Tachyarrhythmia Hospitalization 5/17/2011 50 Male 2/28/2012 Physician Germany
Primary
Secondary
Dysphonia Hospitalization 8/1/2010 Female 2/27/2012 Physician Germany
Primary
Concomitant
Somnolence Hospitalization 5/17/2011 50 Male 2/28/2012 Physician Germany
Primary
Secondary
Coagulation Time Abnormal Other Serious Male 198 lb 3/6/2012 Physician Germany
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 1/1/2007 68 3/9/2012 Physician Germany
Primary
Concomitant
Bradyarrhythmia Other Serious 2/23/2012 67 Female 130 lb 3/19/2012 Physician Germany
Primary
Secondary
Concomitant
Rash Hospitalization 3/1/2011 Female 159 lb 3/21/2012 Physician Germany
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 1/1/2007 68 3/23/2012 Physician Germany
Primary
Concomitant
Coagulation Time Abnormal Other Serious Male 198 lb 3/28/2012 Physician Germany
Primary
Secondary
Concomitant
Syncope Other Serious 12/22/2008 4/6/2012 Physician Germany
Primary
Concomitant
Tooth Discolouration Hospitalization 2/22/2012 91 Female 161 lb 4/17/2012 Physician Germany
Primary
Concomitant
Cardiac Disorder Life Threatening 2/20/2012 81 Female 120 lb 4/26/2012 Physician Germany
Primary
Concomitant
Drug Level Decreased Hospitalization 3/3/2011 50 Female 198 lb 4/27/2012 Physician Belgium
Primary
Concomitant

Drug Data