Levothyroxine combined with Metoprolol

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Angioedema Hospitalization 12/10/2008 73 Female 170 lb 12/11/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 6/22/2008 78 Female 129 lb 12/15/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 7/25/2006 30 Female 174 lb 12/16/2008 United States
Primary
Secondary
Concomitant
Insomnia Death 9/1/2008 85 Female 100 lb 12/19/2008 Physician United States
Primary
Concomitant
Visual Impairment Life Threatening 65 Male 238 lb 12/20/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 1/21/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 1/27/2009 Consumer United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 85 Female 3/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 3/13/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/31/2008 Female 3/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2009 Female 3/20/2009 United States
Primary
Secondary
Concomitant
Pain Hospitalization 4/1/2004 68 Male 250 lb 3/27/2009 Consumer United States
Primary
Concomitant
Transaminases Increased Other Serious 4/1/2008 Female 3/27/2009 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2008 Male 167 lb 3/30/2009 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 85 Female 3/31/2009 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 3/1/2009 Female 199 lb 5/8/2009 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 3/1/2009 Female 199 lb 6/23/2009 Consumer United States
Primary
Concomitant
Sinus Disorder 1/1/2008 Male 7/7/2009 Consumer
Primary
Concomitant
Anaemia Other Serious 5/1/2009 Female 8/11/2009 Physician United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 10/1/2008 61 Female 247 lb 8/12/2009 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/2/2007 64 Male 272 lb 8/12/2009 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/1985 Female 8/12/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 7/31/2009 61 Female 8/14/2009 Physician Germany
Primary
Concomitant
Wound Drainage Other Serious 3/1/2009 Female 187 lb 8/14/2009 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/10/2009 United States
Primary
Concomitant
Vomiting Death 77 Female 8/4/2009 United States
Primary
Concomitant
Sepsis Syndrome Hospitalization Female 8/18/2009 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization Female 161 lb 8/19/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2003 75 8/18/2009 Pharmacist Canada
Primary
Concomitant
Disease Recurrence Hospitalization 3/4/2009 Male 243 lb 8/20/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 83 Female 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 5/15/2009 66 Female 152 lb 8/18/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 72 Female 8/14/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Disability 2/1/2009 Female 8/18/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Headache 9/5/2008 Female 8/21/2009 United States
Primary
Concomitant
Muscular Weakness 8/1/2008 Female 8/21/2009 United States
Primary
Concomitant
Pruritus Male 8/21/2009 United States
Primary
Concomitant
Headache Male 8/21/2009 United States
Primary
Concomitant
Pruritus 10/2/2008 Female 165 lb 8/22/2009 Other Health Professional
Primary
Concomitant
Feeling Hot 9/10/2008 Male 8/22/2009 United States
Primary
Concomitant
Pruritus Female 8/22/2009 United States
Primary
Concomitant
Swollen Tongue Hospitalization 8/1/2009 Female 8/26/2009 Consumer United States
Primary
Concomitant
Headache Male 240 lb 8/29/2009 United States
Primary
Concomitant
Feeling Hot 5/13/2009 Female 240 lb 8/29/2009 United States
Primary
Concomitant
Middle Insomnia Female 157 lb 8/29/2009 United States
Primary
Concomitant
Weight Decreased 7/19/2009 81 Female 161 lb 9/3/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Death 1/1/2007 58 Female 9/3/2009 Lawyer United States
Primary
Concomitant
Sensation Of Foreign Body 7/25/2009 Female 9/4/2009 Consumer
Primary
Concomitant
Ketoacidosis Other Serious 11/2/2005 48 Male 318 lb 9/7/2009 United States
Primary
Concomitant
Pneumonitis Other Serious 7/10/2008 Male 9/8/2009 Other Health Professional United States
Primary
Concomitant
Sepsis Syndrome Hospitalization Female 9/8/2009 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 3/1/2009 Female 199 lb 9/8/2009 Consumer United States
Primary
Concomitant
Death Death Female 140 lb 9/9/2009 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 9/18/2009 Male 160 lb 10/1/2009 Consumer United States
Primary
Concomitant
Pathological Fracture Hospitalization 72 Male 9/23/2009 United States
Primary
Concomitant
Surgery Hospitalization 72 Female 9/25/2009 United States
Primary
Concomitant
Sepsis Other Serious 9/18/2009 Female 10/7/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 9/18/2009 78 Female 148 lb 10/8/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 51 Female 223 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/18/2009 79 Female 139 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Death 5/1/2009 Female 140 lb 10/12/2009 Physician United States
Primary
Concomitant
Sepsis Other Serious 9/18/2009 Female 10/16/2009 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2009 Female 261 lb 11/5/2009 Consumer United States
Primary
Concomitant
Sepsis Other Serious 9/18/2009 Female 11/6/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 72 Female 11/4/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Other Serious 77 Female 11/4/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 87 Female 11/4/2009 United States
Primary
Concomitant
Thrombosis Other Serious 9/18/2009 Male 160 lb 11/16/2009 Consumer United States
Primary
Concomitant
Sepsis Other Serious 9/18/2009 Female 11/13/2009 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2009 Female 261 lb 12/11/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 4/1/2009 Female 154 lb 1/26/2010 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/18/2009 65 Female 2/12/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious Female 280 lb 3/9/2010 Consumer United States
Primary
Concomitant
Death Death 2/19/2010 3/9/2010 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization Female 3/3/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Death Female 3/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Surgery Other Serious 2/1/2010 Female 90 lb 3/12/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 51 Female 223 lb 3/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hip Surgery Other Serious 1/1/2008 87 Female 90 lb 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Retinal Artery Occlusion Other Serious 1/11/2010 56 Female 134 lb 4/26/2010 Physician Canada
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/11/2009 63 Male 176 lb 4/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2010 88 Male 4/19/2010 Consumer United States
Primary
Concomitant
Ulcer Hospitalization 4/1/2010 62 Male 262 lb 4/27/2010 Consumer United States
Primary
Concomitant
Troponin T Increased Other Serious 3/27/2010 61 Male 201 lb 4/28/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4/1/2010 39 Female 139 lb 5/4/2010 Pharmacist United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening Female 282 lb 5/4/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2010 68 Male 280 lb 5/5/2010 Consumer United States
Primary
Secondary
Concomitant
Retinal Artery Occlusion Other Serious 1/11/2010 56 Female 134 lb 5/5/2010 Physician Canada
Primary
Concomitant
Stent Placement Hospitalization Male 5/5/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 5/4/2010 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 38 Male 6/24/2010 Physician United States
Primary
Concomitant
Pneumonia Death 1/1/2010 60 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Coagulation Time Prolonged 78 Male 130 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Coagulation Time Prolonged 7/24/2007 69 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/19/2009 78 Female 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing 4/1/2009 Female 6/29/2010 Pharmacist United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 5/19/2009 78 Female 6/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 24 Female 128 lb 6/30/2010 United States
Primary
Concomitant
Thrombosis Other Serious 1/1/2007 78 Male 119 lb 7/12/2010 Physician United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting 4/21/2007 65 Female 151 lb 7/12/2010 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 4/1/2010 39 Female 139 lb 7/16/2010 Pharmacist United States
Primary
Concomitant
Acute Pulmonary Oedema Other Serious 7/13/2010 66 Female 7/28/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 5/14/2002 76 Female 165 lb 7/26/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/22/2008 49 Female 8/3/2010 Other Health Professional United States
Primary
Concomitant
Oedema Mouth Other Serious 9/1/2008 68 Female 236 lb 8/3/2010 Consumer United States
Primary
Concomitant
Feeling Abnormal 2/18/2009 70 Female 8/3/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/1/2008 75 Male 8/6/2010 Other Health Professional United States
Primary
Concomitant
Incoherent Hospitalization 1/1/2010 62 Male 8/6/2010 Physician United States
Primary
Concomitant
Cough 1/1/2006 74 Female 272 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 130 lb 8/6/2010 Consumer United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/1/2008 75 Male 8/9/2010 Other Health Professional United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 4/13/2010 72 Female 185 lb 8/10/2010 Physician United States
Primary
Secondary
Concomitant
Macular Oedema Other Serious 7/1/2010 Female 8/10/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 9/1/2009 78 Male 185 lb 8/10/2010 Consumer United States
Primary
Concomitant
Tachypnoea Other Serious 10/12/2009 47 Male 8/11/2010 Other Health Professional Germany
Primary
Concomitant
Swelling Other Serious 4/21/2008 56 Female 8/11/2010 Lawyer United States
Primary
Concomitant
Urticaria Other Serious 6/14/2010 79 Female 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Arterial Stent Insertion Other Serious 6/1/2010 84 Male 8/24/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/11/2010 63 Female 184 lb 8/24/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 51 Male 8/25/2010 Other Health Professional United States
Primary
Concomitant
Flushing 7/1/2009 68 Male 190 lb 8/27/2010 United States
Primary
Concomitant
Flushing 10/22/2009 65 Male 210 lb 8/28/2010 United States
Primary
Concomitant
Flushing 11/1/2009 52 Female 150 lb 8/28/2010 United States
Primary
Concomitant
Feeling Hot 11/5/2009 66 Female 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation 8/1/2009 80 Male 165 lb 8/28/2010 United States
Primary
Concomitant
Myalgia Female 278 lb 8/28/2010 United States
Primary
Concomitant
Fatigue 12/1/2009 73 Male 190 lb 8/28/2010 United States
Primary
Secondary
Concomitant
Flushing 12/1/2009 70 Female 151 lb 8/28/2010 United States
Primary
Concomitant
Tooth Disorder 12/1/2009 59 Male 8/28/2010 United States
Primary
Concomitant
Tooth Disorder 12/1/2009 59 Male 8/28/2010 United States
Primary
Concomitant
Rash 1/26/2010 78 Male 138 lb 8/28/2010 Consumer United States
Primary
Secondary
Concomitant
Dysuria 2/27/2010 74 Male 8/28/2010 United States
Primary
Concomitant
Flushing 1/1/2009 63 Female 200 lb 8/28/2010 Consumer United States
Primary
Concomitant
Flushing 3/16/2010 51 Male 220 lb 8/28/2010 Consumer United States
Primary
Concomitant
Oral Pain 4/9/2010 75 Female 135 lb 8/28/2010 United States
Primary
Concomitant
Flushing Female 155 lb 8/29/2010 Consumer United States
Primary
Concomitant
Pruritus Other Serious 5/10/2010 78 Male 178 lb 8/29/2010 Physician United States
Primary
Concomitant
Flushing 4/1/2010 62 260 lb 8/29/2010 United States
Primary
Concomitant
Swelling Female 175 lb 8/29/2010 Consumer United States
Primary
Concomitant
Flushing Male 213 lb 8/29/2010 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased 5/1/2010 57 Male 217 lb 8/29/2010 Consumer United States
Primary
Concomitant
Flushing 1/1/2010 64 Male 159 lb 8/29/2010 Consumer United States
Primary
Concomitant
Pruritus 1/1/2008 67 Female 180 lb 8/29/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased 7/18/2010 91 Male 160 lb 8/29/2010 Consumer United States
Primary
Concomitant