Levothyroxine combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Fibrillation Death 5/1/2007 Male 293 lb 8/18/2008 Physician United States
Primary
Concomitant
Tremor Hospitalization 9/26/2008 54 Female 249 lb 1/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Occult Blood Positive Hospitalization 9/9/2008 64 Female 284 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Dyskinesia Hospitalization 1/1/1998 55 Female 1/23/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 2/27/2009 3/17/2009 Other Health Professional Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 2/11/2009 Female 173 lb 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 4/1/2004 68 Male 250 lb 3/27/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/11/2002 Female 198 lb 3/27/2009 Physician Spain
Primary
Concomitant
Anal Abscess Hospitalization 3/30/2009 4/7/2009 Pharmacist Brazil
Primary
Concomitant
Anal Abscess Other Serious 3/30/2009 4/20/2009 Brazil
Primary
Concomitant
Myocardial Infarction Life Threatening 2/27/2009 4/24/2009 Other Health Professional Brazil
Primary
Concomitant
Anal Abscess Hospitalization 3/30/2009 51 5/15/2009 Pharmacist Brazil
Primary
Concomitant
Sepsis Hospitalization 12/1/2004 60 Male 226 lb 6/1/2009 Other Health Professional United States
Primary
Concomitant
Palpitations Hospitalization 73 Female 5/28/2009 United States
Primary
Concomitant
Insomnia Hospitalization 5/22/2009 63 Male 138 lb 6/1/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 5/22/2008 63 Male 141 lb 6/25/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 7/1/2009 Other Health Professional United States
Primary
Concomitant
Hypoxic Encephalopathy Death 73 Male 7/28/2009 Czech Republic
Primary
Concomitant
Rectal Polyp Other Serious 6/1/2009 Female 150 lb 8/6/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 11/28/2006 161 lb 8/11/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/10/2009 United States
Primary
Concomitant
Skin Burning Sensation 8/6/2008 Female 8/21/2009 United States
Primary
Concomitant
Erythema 7/27/2008 Female 8/21/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2000 51 Female 190 lb 8/24/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 79 9/11/2009 Other Health Professional United States
Primary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/6/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rectal Polyp Other Serious 6/1/2009 Female 150 lb 11/10/2009 Pharmacist United States
Primary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 11/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Injury Hospitalization 6/12/2009 73 Male 198 lb 11/18/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 12/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/1/2010 Male 200 lb 2/1/2010 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 12/1/2009 Female 240 lb 2/8/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 165 lb 2/23/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious Female 280 lb 3/9/2010 Consumer United States
Primary
Concomitant
Mantle Cell Lymphoma Other Serious 2/10/2010 Male 157 lb 3/11/2010 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/15/2010 Male 267 lb 3/26/2010 Pharmacist United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 59 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 165 lb 4/8/2010 Consumer United States
Primary
Concomitant
Toe Amputation Hospitalization 65 Male 4/22/2010 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 1/1/2010 66 Female 4/22/2010 Physician United Kingdom
Primary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 76 Female 4/19/2010 Physician United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 64 Female 213 lb 4/26/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2009 58 Female 159 lb 4/27/2010 Consumer United States
Primary
Concomitant
Dizziness Other Serious 3/25/2010 62 Male 227 lb 4/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 1/1/1997 57 Female 120 lb 4/29/2010 Consumer United States
Primary
Secondary
Concomitant
Hemiparesis Other Serious 12/28/2009 79 Female 4/28/2010 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 2/1/2010 69 Male 154 lb 4/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Memory Impairment 38 Female 218 lb 4/30/2010 Consumer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Female 190 lb 5/3/2010 Consumer United States
Primary
Concomitant
Surgery Other Serious 1/13/2010 56 Female 160 lb 6/4/2010 Physician United States
Primary
Secondary
Concomitant
Anal Abscess Hospitalization 6/8/2010 52 Male 189 lb 6/14/2010 Brazil
Primary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2009 56 Female 149 lb 6/29/2010 Consumer United States
Primary
Concomitant
Nausea 5/1/2007 60 Female 211 lb 7/13/2010 Consumer United States
Primary
Concomitant
Anal Abscess Hospitalization 4/10/2010 52 Male 189 lb 7/16/2010 Pharmacist Brazil
Primary
Concomitant
Myalgia Female 7/31/2010 Pharmacist United States
Primary
Concomitant
Oedema Peripheral 2/1/2009 56 Female 260 lb 8/3/2010 Consumer United States
Primary
Concomitant
Urinary Incontinence 1/1/2009 85 Female 160 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 10/12/2009 47 Male 8/11/2010 Other Health Professional Germany
Primary
Concomitant
Macular Degeneration Other Serious 2/1/2010 35 Male 300 lb 8/11/2010 Other Health Professional United States
Primary
Concomitant
Flatulence 7/10/2010 85 Female 8/16/2010 Consumer
Primary
Concomitant
Pancreatitis Other Serious 6/1/2010 60 Female 322 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Nausea 6/1/2010 58 Female 193 lb 8/16/2010 Consumer United States
Primary
Concomitant
Dizziness 6/26/2010 67 Male 250 lb 8/16/2010 Consumer United States
Primary
Concomitant
Flushing Female 125 lb 8/16/2010 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 8/19/2010 Physician United States
Primary
Secondary
Concomitant
Abdominal Wall Abscess Hospitalization 11/30/2009 46 Female 215 lb 8/25/2010 Physician United Kingdom
Primary
Concomitant
Nausea 70 Female 8/25/2010 Consumer United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 5/26/2010 61 Female 285 lb 8/26/2010 Consumer United States
Primary
Secondary
Concomitant
Flushing Female 195 lb 8/27/2010 United States
Primary
Concomitant
Skin Burning Sensation 8/14/2009 70 Female 8/27/2010 United States
Primary
Concomitant
Flushing 9/1/2009 Female 175 lb 8/27/2010 United States
Primary
Concomitant
Skin Burning Sensation 9/17/2009 67 Female 218 lb 8/27/2010 United States
Primary
Concomitant
Sensory Disturbance 1/1/1999 61 Male 190 lb 8/28/2010 United States
Primary
Concomitant
Feeling Jittery 10/1/2009 59 Female 209 lb 8/28/2010 United States
Primary
Concomitant
Flushing 10/22/2009 65 Male 210 lb 8/28/2010 United States
Primary
Concomitant
Feeling Hot 11/5/2009 66 Female 8/28/2010 United States
Primary
Concomitant
Flushing 1/13/2010 56 Female 165 lb 8/28/2010 United States
Primary
Concomitant
Flushing 1/12/2010 56 Male 180 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation Male 215 lb 8/28/2010 United States
Primary
Concomitant
Dizziness 2/12/2010 64 Female 157 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation 3/10/2010 57 Female 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation 2/15/2010 Female 220 lb 8/29/2010 United States
Primary
Concomitant
Pruritus 5/1/2010 67 Female 8/29/2010 United States
Primary
Concomitant
Muscle Spasms 4/14/2010 Male 160 lb 8/29/2010 Consumer United States
Primary
Concomitant
Paraesthesia 5/17/2010 70 Male 224 lb 8/29/2010 Consumer United States
Primary
Concomitant
Hyperhidrosis 5/18/2010 68 Female 242 lb 8/29/2010 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 5/10/2010 53 Male 8/29/2010 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2010 75 Female 8/29/2010 Consumer United States
Primary
Concomitant
Vertigo 1/1/2009 60 Male 235 lb 8/29/2010 Consumer United States
Primary
Concomitant
Nervousness Other Serious 8/25/2010 63 Female 9/1/2010 Consumer United Kingdom
Primary
Concomitant
Tremor Hospitalization 1/30/2003 55 Female 198 lb 9/3/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 39 Female 290 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/1/2002 50 Male 9/8/2010 United States
Primary
Concomitant
Cholelithiasis Hospitalization 8/3/2010 63 Female 176 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Vulvovaginal Pruritus 4/1/2009 78 Female 291 lb 9/14/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 46 Male 167 lb 9/15/2010 Consumer United States
Primary
Concomitant
Pain In Extremity 4/1/2010 59 Female 172 lb 9/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Polyp Other Serious 6/1/2009 73 Female 150 lb 9/16/2010 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious Female 280 lb 9/16/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 56 Female 149 lb 9/16/2010 Consumer United States
Primary
Concomitant
Tremor Hospitalization 7/11/2010 80 Female 9/16/2010 Consumer Colombia
Primary
Concomitant
Drug Ineffective 11/1/2009 73 Female 180 lb 9/18/2010 Consumer United States
Primary
Concomitant
Mood Swings 52 Female 9/20/2010 United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2010 46 Female 250 lb 9/20/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2010 81 Female 162 lb 9/15/2010 United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 9/19/2010 56 Female 270 lb 9/28/2010 Consumer Canada
Primary
Secondary
Concomitant
Parosmia 9/15/2010 68 Female 185 lb 9/30/2010 Consumer United States
Primary
Concomitant
Product Taste Abnormal 9/29/2010 88 Male 187 lb 10/6/2010 Pharmacist United States
Primary
Concomitant
Catheterisation Cardiac Hospitalization Female 235 lb 10/6/2010 Physician United States
Primary
Concomitant
Upper Limb Fracture Other Serious 9/19/2010 56 Female 270 lb 10/6/2010 Physician Canada
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/2/2009 55 Female 244 lb 10/7/2010 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious Female 175 lb 10/7/2010 Physician Canada
Primary
Concomitant
Pneumonia Hospitalization 1/1/2009 72 Female 170 lb 10/4/2010 Consumer United States
Primary
Concomitant
Arthropod Bite 10/1/2010 61 Female 222 lb 10/7/2010 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 9/12/2010 34 Male 10/8/2010 Consumer United States
Primary
Concomitant
Syncope Hospitalization 2/15/2009 73 Female 141 lb 10/8/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 7/24/2008 70 Female 189 lb 10/7/2010 Physician United States
Primary
Concomitant
Shock Other Serious 7/20/2007 60 Female 207 lb 10/7/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 10/11/2010 United States
Primary
Concomitant
Sudden Cardiac Death Death 2/10/2010 76 Female 203 lb 10/6/2010 Other Health Professional
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 226 lb 10/18/2010 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/12/2009 46 Female 238 lb 10/19/2010 Physician United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2004 45 Female 224 lb 10/21/2010 United States
Primary
Concomitant
Lip Swelling Other Serious 9/19/2010 10/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Extrasystoles Other Serious 6/3/2010 77 Male 10/22/2010 Physician United States
Primary
Concomitant
Hypotension Other Serious 9/3/2010 56 Female 209 lb 10/22/2010 Physician United States
Primary
Concomitant
Product Taste Abnormal 9/29/2010 88 Male 187 lb 10/22/2010 Consumer United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/8/2010 56 Female 315 lb 10/25/2010 Physician United States
Primary
Concomitant
Rib Fracture Hospitalization 1/1/2010 61 Female 176 lb 10/25/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/13/2009 52 Female 306 lb 10/21/2010 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 9/12/2010 34 Male 10/26/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization Female 178 lb 10/25/2010 Consumer United States
Primary
Concomitant
Overdose 64 Female 10/13/2010 Consumer United States
Primary
Concomitant
Dysphonia 66 Female 10/13/2010 Consumer United States
Primary
Concomitant
Haemoptysis 79 Female 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Fall Other Serious 9/14/2010 63 Female 10/29/2010 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/18/2010 43 Female 10/29/2010 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 7/1/2010 62 Female 180 lb 11/2/2010 Physician United States
Primary
Concomitant
Lip Swelling Other Serious 32 Female 10/21/2010 Other Health Professional
Primary
Concomitant
Sudden Death Death 9/2/2010 65 Female 175 lb 11/4/2010 Other Health Professional Colombia
Primary
Concomitant
Tremor Other Serious 10/1/2010 57 Female 155 lb 11/5/2010 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 88 Female 137 lb 11/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/23/2010 54 Male 11/12/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 76 Female 168 lb 11/12/2010 Consumer United States
Primary
Secondary
Concomitant
Sensory Disturbance 8/1/2010 46 Female 227 lb 11/16/2010 Consumer United States
Primary
Concomitant

Drug Data