Levothyroxine combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Musculoskeletal Stiffness 4/7/2008 83 Female 7/23/2008 United States
Primary
Concomitant
Renal Impairment Hospitalization 7/20/2006 45 Male 241 lb 8/26/2008 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2006 44 Male 250 lb 8/26/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 Male 297 lb 8/25/2008 Consumer United States
Primary
Concomitant
Varicose Vein Female 144 lb 8/27/2008 Consumer United States
Primary
Concomitant
Pain Hospitalization 4/1/2004 68 Male 250 lb 8/28/2008 Consumer United States
Primary
Concomitant
Neck Pain 7/2/2008 Male 8/29/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2006 53 Male 211 lb 8/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Muscle Twitching 8/1/2008 Male 8/29/2008 United States
Primary
Concomitant
Angioedema Hospitalization 12/10/2008 73 Female 170 lb 12/11/2008 Pharmacist United States
Primary
Concomitant
Drug Ineffective 11/1/2008 Female 12/30/2008 Consumer
Primary
Concomitant
Pallor Other Serious 81 Female 1/5/2009
Primary
Secondary
Pallor Other Serious 81 Female 1/5/2009
Primary
Secondary
Postoperative Fever Hospitalization 12/1/2004 60 Male 226 lb 1/7/2009 Physician United States
Primary
Concomitant
Tremor Hospitalization 9/26/2008 54 Female 249 lb 1/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 11/29/2007 Female 1/20/2009 Consumer United States
Primary
Concomitant
Staphylococcal Sepsis Other Serious 7/14/2008 Female 205 lb 2/2/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 11/1/2008 Female 2/3/2009 Brazil
Primary
Concomitant
Pancreatitis Other Serious 11/29/2007 Female 213 lb 1/28/2009 Physician United States
Primary
Concomitant
Wheezing 83 Male 165 lb 3/18/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/20/2009 Female 4/24/2009 Consumer
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/3/2009 68 Female 5/15/2009 Pharmacist United States
Primary
Concomitant
Knee Arthroplasty Hospitalization 4/22/2009 Female 187 lb 6/15/2009 Czech Republic
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 52 Female 298 lb 6/24/2009 United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 22 Female 6/23/2009 Spain
Primary
Concomitant
Toxic Encephalopathy Hospitalization 5/20/2009 50 Female 8/7/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 72 Female 7/30/2009 United States
Primary
Concomitant
Syncope Hospitalization 55 Female 7/30/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 72 Female 8/14/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 3/5/2003 71 Female 8/18/2009 United States
Primary
Concomitant
Nausea Hospitalization 64 Female 8/20/2009 Lawyer United States
Primary
Concomitant
Off Label Use Other Serious 1/1/2009 Female 175 lb 8/26/2009 Physician United States
Primary
Concomitant
Muscle Spasms Male 250 lb 8/29/2009 United States
Primary
Concomitant
Weight Increased Other Serious Female 8/28/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 Female 8/31/2009
Primary
Concomitant
Therapeutic Response Decreased Hospitalization Male 178 lb 9/4/2009 Physician United States
Primary
Concomitant
Uterine Neoplasm Hospitalization 2/23/2009 Female 9/4/2009 Other Health Professional Norway
Primary
Concomitant
Weight Decreased Hospitalization 3/5/2003 71 Female 11/9/2009 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/12/2009 Female 238 lb 11/27/2009 Physician United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 22 Female 3/2/2010 Other Health Professional Germany
Primary
Concomitant
Hypotension Other Serious 12/1/2007 Female 3/2/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Female 135 lb 3/12/2010 Consumer United States
Primary
Concomitant
Ventricular Septal Defect Congenital Anomaly 11/5/2009 Male 7 lb 3/12/2010 Consumer United States
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 11/5/2009 Male 7 lb 4/1/2010 Other Health Professional United States
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/1/2005 41 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 4/13/2010 68 Male 240 lb 4/20/2010 Consumer United States
Primary
Concomitant
Pneumocephalus Other Serious 2/10/2010 76 Male 157 lb 4/20/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization Female 4/22/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/11/2010 81 Female 5/4/2010 Physician Argentina
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/22/2010 50 Male 296 lb 6/21/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 22 Male 450 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 49 Male 290 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 9/2/2009 55 Male 207 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 3/29/2010 38 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Myelofibrosis Other Serious 11/25/2008 76 Male 192 lb 7/12/2010 Physician Canada
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 6/1/2009 71 Female 187 lb 7/28/2010 Consumer Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 65 Female 183 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Septal Defect Other Serious 11/5/2009 Male 7/27/2010 United States
Primary
Secondary
Tremor Hospitalization 7/1/2010 80 Female 8/3/2010 Consumer Colombia
Primary
Concomitant
Weight Decreased Hospitalization Female 172 lb 8/4/2010 Consumer United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/1/2008 75 Male 8/6/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased 4/1/2006 63 Female 165 lb 8/6/2010 Consumer United States
Primary
Secondary
Concomitant
Cough 1/1/2006 74 Female 272 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 1/1/2008 75 Male 8/9/2010 Other Health Professional United States
Primary
Concomitant
Completed Suicide Death 7/16/2010 23 Female 8/9/2010 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 78 Male 175 lb 8/9/2010 Other Health Professional United States
Primary
Concomitant
Dementia Alzheimer's Type Other Serious 6/1/2009 71 Female 187 lb 8/9/2010 Consumer Brazil
Primary
Secondary
Concomitant
Panic Attack 60 Female 8/9/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 66 Male 8/10/2010 Consumer United States
Primary
Concomitant
Neck Pain 7/31/2010 86 Male 8/12/2010 Consumer
Primary
Concomitant
Weight Decreased Hospitalization 7/4/2010 76 Female 173 lb 8/12/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/14/2010 50 Male 8/18/2010 Physician Germany
Primary
Concomitant
Nausea Hospitalization 6/14/2010 77 Female 8/18/2010 Physician Canada
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 11/1/2009 61 Female 240 lb 8/19/2010 Consumer United States
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 53 Male 282 lb 8/31/2010 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/5/2008 80 Female 155 lb 9/14/2010 Other Health Professional United States
Primary
Concomitant
Visual Impairment 52 Female 307 lb 9/20/2010 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 8/1/2010 62 Female 9/2/2010 United States
Primary
Concomitant
Insomnia 6/1/2010 60 Female 266 lb 9/20/2010 United States
Primary
Concomitant
Mental Status Changes Hospitalization 8/19/2010 87 Male 10/12/2010 Pharmacist United States
Primary
Concomitant
Lip Swelling Other Serious 9/19/2010 32 Female 10/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Lip Swelling Other Serious 9/19/2010 32 Female 10/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pregnancy 1/1/2009 24 Female 10/25/2010 Consumer United States
Primary
Secondary
Weight Decreased Hospitalization 7/4/2010 73 Female 173 lb 11/8/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 7/1/2009 55 Male 8/25/2010 Consumer United States
Primary
Concomitant
Thirst 3/1/2010 44 Female 360 lb 12/13/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 50 Female 12/16/2010 Pharmacist Iceland
Primary
Concomitant
Interacting
Type 2 Diabetes Mellitus 9/11/2008 51 Female 228 lb 12/20/2010 Consumer
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/23/2010 54 Male 12/22/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 12/23/2010 United States
Primary
Concomitant
Ventricular Septal Defect Congenital Anomaly 11/5/2009 Male 7 lb 1/5/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Murmur Other Serious 11/5/2009 1 Male 7 lb 1/6/2011 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 1/1/2009 37 Female 1/10/2011 Physician United States
Primary
Secondary
Abdominal Pain Hospitalization 8/1/2010 Female 1/11/2011 Consumer United States
Primary
Concomitant
Tendonitis Other Serious 5/2/2000 43 Female 270 lb 1/17/2011 Consumer United States
Primary
Concomitant
Hemiparesis Other Serious Female 180 lb 1/14/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission Hospitalization 1/1/2010 53 Female 210 lb 1/24/2011 United States
Primary
Concomitant
Cardio-respiratory Arrest Death 78 Female 1/5/2011 United States
Primary
Concomitant
Cardiac Arrest Death 1/1/2009 37 Female 1/25/2011 Physician United States
Primary
Secondary
Nausea 8/1/2010 63 Male 263 lb 2/25/2011 Physician United States
Primary
Concomitant
Drug Ineffective 12/15/2010 76 Female 2/25/2011 Other Health Professional United States
Primary
Concomitant
Congenital Musculoskeletal Anomaly Congenital Anomaly 2/23/2011 0 Male 2 lb 2/25/2011 Physician United States
Primary
Concomitant
Microcytosis Other Serious 2/3/2011 33 Female 240 lb 3/16/2011 Physician United Kingdom
Primary
Concomitant
Skin Burning Sensation Other Serious 1/1/2010 48 Male 265 lb 3/16/2011 Consumer United States
Primary
Concomitant
Vacterl Syndrome Death 2/23/2011 2 lb 3/16/2011 Physician United States
Primary
Concomitant
Coronary Artery Occlusion Life Threatening 59 Female 118 lb 3/7/2011 United States
Primary
Secondary
Feeling Abnormal Hospitalization 2/1/2011 40 Female 205 lb 3/4/2011 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Death 1/1/2010 84 Female 4/4/2011 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/6/2011 74 Female 7/14/2011 Physician United Kingdom
Primary
Concomitant
Bladder Disorder Other Serious 1/1/2006 47 Male 203 lb 7/15/2011 Physician United States
Primary
Concomitant
Throat Irritation Female 165 lb 9/23/2011 Consumer United States
Primary
Concomitant
Syncope Other Serious 7/8/2011 61 Male 237 lb 9/28/2011 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2011 73 Male 9/28/2011 Physician United States
Primary
Concomitant
Fatigue 8/1/2011 81 Male 9/29/2011 Consumer United States
Primary
Concomitant
Cholecystitis Chronic Hospitalization 7/9/2007 17 Female 209 lb 9/29/2011 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 8/12/2011 83 Female 9/30/2011 Consumer United States
Primary
Concomitant
Acute Myeloid Leukaemia Death Female 105 lb 10/3/2011 Physician United States
Primary
Concomitant
Vomiting Death 3/9/2011 82 Male 10/3/2011 Other Health Professional United Kingdom
Primary
Concomitant
Deep Vein Thrombosis Other Serious 3/25/2011 59 Female 262 lb 10/4/2011 Physician United States
Primary
Concomitant
Faeces Discoloured Hospitalization 6/12/2011 88 Female 10/4/2011 Consumer United States
Primary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 5/1/2010 33 Female 188 lb 10/31/2011 Physician Brazil
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 5/1/2010 33 Female 188 lb 11/13/2011 Physician Brazil
Primary
Secondary
Concomitant
Dyspepsia 6/11/2012 79 Female 6/21/2012 Consumer United States
Primary
Concomitant
Blood Testosterone Decreased Other Serious 1/1/2008 40 Male 290 lb 6/21/2012 Consumer United States
Primary
Concomitant
Rhinorrhoea Other Serious 77 Female 130 lb 6/21/2012 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 5/2/2011 53 Female 203 lb 6/22/2012 Other Health Professional United States
Primary
Concomitant
Urine Analysis Abnormal Other Serious 12/1/2011 45 Female 234 lb 6/20/2012 Consumer United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Male 269 lb 6/26/2012 Consumer United States
Primary
Concomitant
Skin Exfoliation 4/1/2012 68 Male 6/26/2012 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2012 69 Female 6/27/2012 Consumer New Zealand
Primary
Concomitant
Drug Ineffective 74 Male 194 lb 6/27/2012 Consumer United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 10/4/2011 49 Male 160 lb 6/28/2012 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 10/19/2011 36 Female 6/28/2012 Pharmacist United States
Primary
Concomitant
Chills Hospitalization 3/1/2012 66 Female 198 lb 6/28/2012 Physician United States
Primary
Concomitant
Asthenia Other Serious 1/1/2000 76 Female 6/28/2012 Other Health Professional United States
Primary
Concomitant
Condition Aggravated Hospitalization Female 175 lb 6/29/2012 Lawyer United States
Primary
Concomitant
Electrolyte Imbalance Disability 1/1/2001 64 Female 6/27/2012 Consumer United States
Primary
Concomitant
Tendon Rupture Other Serious 2000 Female 200 lb 3/15/2013 Other Health Professional Us
Primary
Concomitant
Osteonecrosis Other Serious Female 190 lb 8/24/2012 Physician Us
Primary
Concomitant
Urinary Tract Infection Other Serious 5/18/2012 78 Female 88 lb 9/14/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 2003 57 Female 220 lb 10/22/2012 Consumer Us
Primary
Secondary
Concomitant
Oedema Other Serious 49 Male 247 lb 11/9/2012 Consumer Gb
Primary
Secondary
Concomitant
Spinal Disorder Other Serious 2006 72 Female 267 lb 2/12/2013 Consumer Us
Primary
Secondary
Concomitant
Pancreatitis Chronic Other Serious 59 Female 12/31/2012 Consumer De
Primary
Concomitant
Vomiting 6/2012 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Malaise 1/2012 46 Female 152 lb 2/11/2013 Consumer Us
Primary
Concomitant
Rash 71 Female 2/11/2013 Consumer Us
Primary
Secondary
Concomitant
Skin Induration 2011 Male 1/28/2013 Physician Country Not Specified
Primary
Concomitant
Injection Site Pain 4/2012 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant

Drug Data