Levoleucovorin Calcium combined with Panitumumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypomagnesaemia Hospitalization 9/21/2010 77 Male 146 lb 10/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Other Serious 9/21/2010 65 Male 121 lb 10/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform 8/5/2010 59 Male 141 lb 10/3/2011 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 11/11/2010 58 Male 121 lb 10/5/2011 Physician Japan
Primary
Concomitant
Colorectal Cancer Death 7/23/2010 59 Male 123 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 9/13/2010 74 Male 141 lb 10/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Fissures Life Threatening 5/7/2011 83 Male 99 lb 10/7/2011 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Death 9/22/2010 77 Male 121 lb 10/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Encephalopathy Other Serious 10/2/2010 66 Male 154 lb 10/7/2011 Other Health Professional Japan
Primary
Concomitant
Colorectal Cancer Other Serious 8/9/2010 61 Male 148 lb 10/10/2011 Other Health Professional Japan
Primary
Concomitant
Dry Skin Hospitalization 10/19/2010 55 Male 108 lb 10/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 10/18/2010 75 Female 115 lb 10/11/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 10/29/2010 73 Male 119 lb 10/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Maculo-papular Death 10/27/2010 55 Male 119 lb 10/11/2011 Physician Japan
Primary
Concomitant
Haemorrhoids Other Serious 9/17/2010 50 Male 154 lb 10/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 10/24/2010 75 Female 121 lb 10/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 8/24/2010 75 Male 112 lb 10/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 12/3/2010 66 Male 165 lb 10/14/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Disorder Death 10/14/2010 52 Male 123 lb 10/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 9/7/2010 62 Male 95 lb 10/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 9/30/2010 59 Male 141 lb 10/19/2011 Other Health Professional Japan
Primary
Secondary
Blood Potassium Increased Death 12/7/2010 67 Male 110 lb 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 9/1/2011 71 Male 10/19/2011 Physician Japan
Primary
Concomitant
Paronychia Hospitalization 7/27/2010 61 Female 168 lb 10/21/2011 Physician Japan
Primary
Concomitant
Death Death 7/7/2011 73 Male 112 lb 10/24/2011 Other Health Professional Japan
Primary
Secondary
Thrombosis Hospitalization 9/1/2011 76 Female 10/24/2011 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 11/11/2010 58 Male 121 lb 10/24/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Death 8/11/2010 60 Male 150 lb 10/24/2011 Other Health Professional Japan
Primary
Concomitant
Condition Aggravated Life Threatening 8/4/2010 81 Male 126 lb 10/24/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Device Occlusion Other Serious 12/8/2010 56 Male 128 lb 10/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 7/21/2010 71 Female 79 lb 10/26/2011 Physician Japan
Primary
Secondary
Concomitant
Mouth Ulceration Hospitalization 8/12/2010 63 Male 126 lb 10/26/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/29/2010 70 Male 128 lb 10/26/2011 Physician Japan
Primary
Secondary
Interstitial Lung Disease Death 8/16/2011 65 Male 134 lb 10/27/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/13/2010 70 Female 106 lb 10/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 8/31/2010 72 Male 176 lb 10/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 6/29/2011 75 Male 112 lb 10/27/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/29/2010 65 Male 104 lb 10/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Chromaturia Hospitalization 9/1/2011 76 Female 10/27/2011 Physician Japan
Primary
Secondary
Hypocalcaemia Hospitalization 8/20/2010 59 Male 187 lb 10/28/2011 Other Health Professional Japan
Primary
Concomitant
Diarrhoea Life Threatening 9/14/2010 78 Male 137 lb 10/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 12/3/2010 66 Male 165 lb 10/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 7/6/2011 74 Male 10/28/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/3/2010 76 Male 99 lb 10/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Glossodynia Death 9/21/2010 65 Male 121 lb 10/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 8/5/2010 70 Male 119 lb 11/1/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/25/2011 72 Male 152 lb 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 7/7/2011 73 Male 112 lb 11/3/2011 Physician Japan
Primary
Secondary
Dry Skin Death 9/24/2010 64 Male 154 lb 11/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Hospitalization 12/20/2010 80 Male 119 lb 11/4/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Death 10/5/2010 69 Male 141 lb 11/9/2011 Other Health Professional Japan
Primary
Concomitant
Dry Skin Death 12/1/2010 55 Female 104 lb 11/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Hospitalization 9/6/2010 55 Male 137 lb 11/9/2011 Physician Japan
Primary
Secondary
Concomitant
Conjunctivitis 9/17/2010 50 Male 154 lb 11/11/2011 Physician Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 7/26/2010 68 Male 141 lb 11/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Enterocolitis Haemorrhagic Hospitalization 10/28/2011 74 Male 132 lb 11/13/2011 Physician Japan
Primary
Secondary
Concomitant
Dry Skin Death 10/27/2010 55 Male 119 lb 11/16/2011 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/30/2010 59 Male 141 lb 11/17/2011 Other Health Professional Japan
Primary
Secondary
Dermatitis Acneiform Hospitalization 9/21/2010 77 Male 146 lb 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 10/2/2010 66 Male 154 lb 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 9/22/2010 77 Male 121 lb 11/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Enterocolitis Haemorrhagic Other Serious 11/1/2011 75 Male 11/21/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Oral Mucosa Erosion Hospitalization 10/24/2011 71 Male 11/21/2011 Physician Japan
Primary
Secondary
Neutrophil Count Decreased Hospitalization 8/18/2011 36 Female 11/22/2011 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Death 11/24/2010 61 Male 108 lb 11/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 4/1/2011 78 Male 11/23/2011 Physician Japan
Primary
Concomitant
Vomiting Other Serious 12/3/2010 76 Male 99 lb 11/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 7/27/2010 61 Female 168 lb 11/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 6/1/2011 72 Female 82 lb 11/24/2011 Physician Japan
Primary
Concomitant
Death Death 37 Male 11/28/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 10/1/2010 51 Male 163 lb 11/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Hospitalization 1/19/2011 79 Male 126 lb 11/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/5/2010 64 Male 119 lb 11/29/2011 Other Health Professional Japan
Primary
Concomitant
Bronchitis Death 8/24/2010 75 Male 112 lb 11/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 12/7/2010 67 Male 110 lb 11/29/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 2/4/2011 57 Male 137 lb 11/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Chromaturia Hospitalization 9/1/2011 76 Female 11/30/2011 Physician Japan
Primary
Secondary
Dry Skin Death 8/3/2010 76 Male 152 lb 11/30/2011 Physician Japan
Primary
Secondary
Concomitant
Fall Hospitalization 8/12/2010 63 Male 126 lb 11/30/2011 Physician Japan
Primary
Secondary
Concomitant
Enterocolitis Death 7/9/2011 74 Male 11/30/2011 Physician Japan
Primary
Concomitant
Granulocytopenia Life Threatening 10/29/2010 70 Male 128 lb 12/2/2011 Physician Japan
Primary
Secondary
Dermatitis Acneiform Death 10/14/2010 52 Male 123 lb 12/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 67 Female 12/6/2011 Physician Japan
Primary
Concomitant
Scrotal Ulcer Other Serious 68 Male 12/7/2011 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 8/4/2010 81 Male 126 lb 12/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pharyngeal Erythema Hospitalization 10/24/2011 71 Male 132 lb 12/8/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 10/12/2011 73 Male 132 lb 12/9/2011 Other Health Professional Japan
Primary
Concomitant
Stomatitis Death 12/9/2010 65 Female 117 lb 12/9/2011 Physician Japan
Primary
Concomitant
Acne Other Serious 9/9/2010 59 Male 126 lb 12/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 5/27/2011 75 Male 119 lb 12/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Other Serious 11/18/2010 75 Male 93 lb 12/12/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 12/15/2010 67 Male 190 lb 12/13/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 10/17/2011 63 Male 12/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 1/19/2011 79 Male 126 lb 12/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 11/14/2010 65 Female 84 lb 12/15/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 37 Male 12/15/2011 Other Health Professional Japan
Primary
Concomitant
Malaise Hospitalization 4/28/2011 79 Male 101 lb 12/15/2011 Physician Japan
Primary
Concomitant
Colorectal Cancer Life Threatening 7/9/2011 74 Male 12/15/2011 Physician Japan
Primary
Concomitant
Hypocalcaemia Hospitalization 7/26/2010 68 Male 141 lb 12/15/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 12/27/2010 83 Male 134 lb 12/16/2011 Other Health Professional Japan
Primary
Concomitant
Diarrhoea Death 11/16/2011 68 Female 128 lb 12/19/2011 Physician Japan
Primary
Secondary
Concomitant
Implant Site Erythema Other Serious 12/3/2010 66 Male 165 lb 12/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 10/11/2010 78 Male 130 lb 12/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/12/2010 63 Male 126 lb 12/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoalbuminaemia Hospitalization 12/2/2011 78 Male 104 lb 12/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 12/16/2011 73 Male 12/28/2011 Other Health Professional Japan
Primary
Concomitant
Colorectal Cancer Death 8/11/2010 60 Male 150 lb 12/29/2011 Other Health Professional Japan
Primary
Concomitant
Rash Maculo-papular Hospitalization 11/1/2010 72 Female 82 lb 12/29/2011 Physician Japan
Primary
Concomitant
Hypomagnesaemia Hospitalization 9/9/2010 81 Female 95 lb 12/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 10/14/2010 52 Male 123 lb 12/30/2011 Physician Japan
Primary
Secondary
Concomitant
Tetany Hospitalization 12/2/2011 78 Male 104 lb 1/6/2012 Physician Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Death 7/2/2010 80 Male 93 lb 1/6/2012 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/5/2010 64 Male 119 lb 1/6/2012 Other Health Professional Japan
Primary
Concomitant
Asthenia Death 11/16/2011 68 Female 128 lb 1/6/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/28/2011 79 Male 101 lb 1/6/2012 Other Health Professional Japan
Primary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 11/4/2010 41 Female 99 lb 1/8/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Fissures Hospitalization 11/4/2010 41 Female 99 lb 1/8/2012 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 10/12/2010 60 Male 128 lb 1/8/2012 Physician Japan
Primary
Secondary
Concomitant
Scrotal Ulcer Other Serious 4/4/2011 68 Male 146 lb 1/9/2012 Other Health Professional Japan
Primary
Concomitant
Hypomagnesaemia Life Threatening 4/11/2011 59 Male 132 lb 1/9/2012 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/6/2010 55 Male 137 lb 1/18/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 12/3/2010 66 Male 165 lb 1/19/2012 Physician Japan
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/10/2012 Male 194 lb 1/24/2012 Other Health Professional Japan
Primary
Concomitant
Hypomagnesaemia Life Threatening 4/11/2011 59 Male 132 lb 1/24/2012 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Death 1/18/2012 58 Male 1/26/2012 Other Health Professional Japan
Primary
Concomitant
Neutrophil Count Decreased Death 1/16/2012 58 Male 97 lb 1/30/2012 Other Health Professional Japan
Primary
Secondary
Hypoalbuminaemia Hospitalization 7/29/2010 62 Male 126 lb 1/31/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/25/2011 72 Male 152 lb 1/31/2012 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 1/7/2012 73 Male 1/31/2012 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious Male 2/2/2012 Other Health Professional Japan
Primary
Concomitant
Blood Sodium Increased Other Serious 7/29/2010 62 Male 126 lb 2/7/2012 Physician Japan
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Hospitalization 10/5/2010 64 Male 119 lb 2/10/2012 Other Health Professional Japan
Primary
Concomitant
Stomatitis Hospitalization 5/27/2011 75 Male 119 lb 2/10/2012 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 11/22/2011 77 Male 104 lb 2/10/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 66 Male 2/14/2012 Other Health Professional Japan
Primary
Concomitant
Dyspnoea Other Serious 11/18/2010 75 Male 93 lb 2/14/2012 Physician Japan
Primary
Concomitant
Thrombosis Other Serious 6/17/2011 63 Male 112 lb 2/16/2012 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Death 2/11/2012 73 Male 2/22/2012 Other Health Professional Japan
Primary
Secondary
Diarrhoea Death 11/24/2010 61 Male 108 lb 2/24/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/8/2011 77 Male 112 lb 2/24/2012 Physician Japan
Primary
Concomitant
Thrombosis In Device Hospitalization 11/10/2010 78 Male 154 lb 2/27/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 7/21/2010 71 Female 79 lb 2/27/2012 Physician Japan
Primary
Secondary
Concomitant
Cheilitis Life Threatening 10/11/2011 73 Male 108 lb 2/28/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Death 11/16/2011 68 Female 128 lb 2/28/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 1/24/2012 69 Male 2/29/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/12/2011 73 Male 132 lb 2/29/2012 Physician Japan
Primary
Concomitant
Nausea Life Threatening 10/11/2011 73 Male 108 lb 3/2/2012 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 66 Male 3/2/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 11/18/2010 75 Male 93 lb 3/5/2012 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 9/13/2010 67 Female 95 lb 3/7/2012 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data