Levofloxacin combined with Velcade

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 4/28/2005 72 Male 126 lb 4/6/2006 Physician Spain
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/28/2005 72 Male 126 lb 6/30/2006 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Death 2/13/2006 69 Male 168 lb 7/6/2006 Physician Germany
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Death 2/13/2006 69 Male 168 lb 8/4/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 4/28/2005 72 Male 126 lb 8/11/2006 Physician Spain
Primary
Secondary
Concomitant
Thrombocytopenia Death 2/13/2006 69 Male 168 lb 8/11/2006 Physician Germany
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 12/7/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 1/12/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/5/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 2/23/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/12/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 5/18/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/15/2006 51 Male 5/11/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/15/2006 52 Male 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Mass Other Serious 12/4/2006 71 Male 5/24/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 6/28/2007 Physician Japan
Primary
Concomitant
Intercostal Neuralgia Other Serious 1/1/2007 Male 119 lb 7/5/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/3/2007 65 Female 90 lb 7/9/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 8/16/2007 Physician Japan
Primary
Concomitant
Myelodysplastic Syndrome Death 5/1/2007 59 Male 119 lb 9/13/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 9/18/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/2/2007 56 Male 181 lb 9/27/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/11/2007 66 Male 148 lb 10/30/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 2/3/2007 60 Male 132 lb 11/5/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/2/2007 56 Male 181 lb 11/15/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 11/22/2007 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/9/2007 58 Male 11/26/2007 Physician Japan
Primary
Concomitant
Sudden Death Other Serious 8/14/2007 38 Unknown 12/3/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/8/2006 71 Male 106 lb 12/14/2007 Physician Japan
Primary
Concomitant
Vomiting Death 5/1/2007 59 Male 119 lb 12/18/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/4/2007 64 Male 139 lb 12/20/2007 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 9/29/2007 60 Male 12/31/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 10/20/2007 57 Male 115 lb 12/31/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/11/2007 66 Male 148 lb 12/28/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/7/2007 67 Female 97 lb 1/3/2008 Physician Japan
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 10/1/2007 55 Male 161 lb 1/3/2008 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/8/2006 71 Male 106 lb 1/31/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/4/2007 64 Male 139 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/20/2007 57 Male 115 lb 2/8/2008 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 5/21/2007 71 Female 121 lb 2/15/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/23/2007 60 Male 130 lb 2/22/2008 Physician Japan
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious 4/11/2007 66 Male 148 lb 2/21/2008 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 2/14/2008 Female 183 lb 2/22/2008 Physician Germany
Primary
Secondary
Concomitant
Neurogenic Bladder Other Serious 9/2/2007 63 Female 117 lb 3/10/2008 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 10/1/2007 55 Male 161 lb 3/10/2008 Physician Japan
Primary
Concomitant
Sputum Culture Positive Other Serious 10/20/2007 57 Male 115 lb 3/14/2008 Physician Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 11/14/2007 54 Male 132 lb 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 2/12/2008 Female 183 lb 3/14/2008 Physician Germany
Primary
Secondary
Concomitant
Micturition Disorder Hospitalization 2/15/2008 73 Male 134 lb 4/1/2008 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 5/21/2007 71 Female 121 lb 4/2/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 12/6/2007 66 Male 139 lb 4/7/2008 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 11/14/2007 54 Male 132 lb 4/10/2008 Physician Japan
Primary
Secondary
Concomitant
Disease Complication Other Serious 11/14/2007 68 Male 4/16/2008 Pharmacist United States
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 10/1/2007 55 Male 161 lb 4/21/2008 Physician Japan
Primary
Concomitant
Neurogenic Bladder Other Serious 9/2/2007 63 Female 117 lb 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 2/15/2008 73 Male 134 lb 4/29/2008 Physician Japan
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Intestine Other Serious 3/5/2005 58 Male 5/8/2008 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/21/2008 71 Male 101 lb 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/26/2007 56 Female 112 lb 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 3/9/2008 77 Male 175 lb 7/31/2008 Physician Germany
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/28/2008 73 Male 123 lb 8/13/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 8/4/2008 53 Female 115 lb 9/1/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 8/4/2008 53 Female 115 lb 9/3/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 8/4/2008 53 Female 115 lb 9/11/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 7/9/2007 66 Male 139 lb 9/29/2008 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 5/21/2007 71 Female 121 lb 9/29/2008 Physician Japan
Primary
Concomitant
Vulval Abscess Death 6/23/2008 60 Female 95 lb 10/2/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/4/2008 61 Male 121 lb 10/13/2008 Physician Japan
Primary
Concomitant
Vision Blurred Other Serious 11/14/2007 68 Male 10/13/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 11/14/2007 68 Male 10/29/2008 Pharmacist United States
Primary
Concomitant
Urinary Retention Death 6/5/2008 60 Female 95 lb 10/31/2008 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 9/2/2008 Male 11/14/2008 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 11/14/2007 68 Male 11/7/2008 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 6/25/2007 64 Male 11/13/2008 Other Health Professional France
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/4/2008 61 Male 121 lb 11/24/2008 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/12/2008 79 Male 155 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/9/2007 66 Male 139 lb 12/23/2008 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Other Serious 5/21/2007 71 Female 121 lb 12/24/2008 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Life Threatening 3/20/2008 80 Female 86 lb 12/24/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 11/19/2008 74 Female 108 lb 1/16/2009 Physician Japan
Primary
Concomitant
Coronary Artery Stenosis Life Threatening 3/20/2008 80 Female 86 lb 2/5/2009 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/25/2007 64 Male 2/6/2009 Other Health Professional France
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/25/2008 64 Male 2/10/2009 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/2/2007 56 Male 181 lb 2/13/2009 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Metastases To Meninges Other Serious 12/16/2008 74 Male 123 lb 3/3/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/30/2008 38 Female 139 lb 3/9/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 1/14/2009 51 Female 152 lb 3/20/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/9/2007 58 Male 3/19/2009 Physician Japan
Primary
Concomitant
Urine Output Decreased Other Serious 1/14/2009 51 Female 152 lb 3/26/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 2/3/2007 60 Male 132 lb 4/10/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/12/2008 79 Male 155 lb 4/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 10/9/2007 58 Male 4/23/2009 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious 11/17/2007 58 Male 192 lb 4/24/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 12/12/2008 69 Female 99 lb 5/8/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/7/2008 77 Male 121 lb 5/29/2009 Physician Hungary
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 5/21/2007 71 Female 121 lb 7/10/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 7/9/2007 66 Male 139 lb 7/10/2009 Physician Japan
Primary
Concomitant
Polyneuropathy Hospitalization 6/23/2009 46 Male 141 lb 7/14/2009 Physician Ukraine
Primary
Concomitant
Tremor Hospitalization 6/23/2009 46 Male 141 lb 8/7/2009 Physician Ukraine
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/2/2007 56 Male 181 lb 8/12/2009 Physician Japan
Primary
Secondary
Concomitant
Tremor Hospitalization 6/23/2009 46 Male 141 lb 8/18/2009 Physician Ukraine
Primary
Concomitant
Liver Disorder Life Threatening 11/16/2007 Male 192 lb 8/25/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 12/12/2008 69 Female 99 lb 8/24/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2008 51 Female 128 lb 8/25/2009 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/23/2009 46 Male 141 lb 8/27/2009 Physician Ukraine
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 11/14/2007 54 Male 132 lb 8/31/2009 Physician Japan
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/26/2008 51 Female 9/3/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Viral Other Serious 6/20/2009 Female 9/3/2009 Physician Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2008 51 Female 128 lb 9/3/2009 Physician United States
Primary
Secondary
Stomatitis Other Serious 6/26/2008 51 Female 128 lb 9/8/2009 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 6/25/2008 51 Female 128 lb 9/14/2009 Physician United States
Primary
Secondary
Concomitant
Disorientation Hospitalization 6/30/2008 65 Male 168 lb 9/17/2009 Physician Germany
Primary
Concomitant
Sepsis Other Serious 9/23/2009 54 Female 123 lb 9/23/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Viral Other Serious 6/20/2009 Female 9/28/2009 Physician Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/5/2007 59 Male 137 lb 9/24/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/20/2009 77 Male 165 lb 9/28/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 9/19/2009 54 Female 123 lb 10/1/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 64 Male 139 lb 10/13/2009 Physician Japan
Primary
Secondary
Concomitant
Granuloma Other Serious 8/5/2007 59 Male 137 lb 10/23/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 64 Male 139 lb 10/24/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 12/12/2008 69 Female 99 lb 11/12/2009 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/3/2007 65 Female 90 lb 12/17/2009 Physician Japan
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 1/14/2009 2/8/2010 Physician France
Primary
Concomitant
Sepsis Other Serious 9/19/2009 54 Female 123 lb 1/28/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/20/2009 77 Male 165 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 1/14/2009 2/23/2010 Physician France
Primary
Concomitant
Thrombosis Hospitalization 12/5/2008 3/26/2010 Physician France
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/5/2008 4/8/2010 Physician France
Primary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 4/23/2010 United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Vascular Insufficiency Other Serious 1/1/1995 57 Male 5/11/2010 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2010 75 Male 203 lb 5/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/14/2010 69 Male 324 lb 5/25/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 1/19/2010 75 Male 203 lb 6/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/9/2010 United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 6/15/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/21/2010 United States
Primary
Secondary
Concomitant

Drug Data