Levofloxacin combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 1/31/2006 85 Female 2/15/2006 United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2003 38 Female 2/13/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/1/2005 Male 154 lb 3/31/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2005 73 Female 4/20/2006 Physician Japan
Primary
Secondary
Tendonitis Other Serious 10/1/2004 68 Male 10/12/2006 Physician Sweden
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Other Serious 11/12/2006 80 Male 12/4/2006 Other Health Professional Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 1/19/2006 39 Female 3/8/2007 Physician Japan
Primary
Secondary
Concomitant
Infection Life Threatening 9/9/2004 31 Female 110 lb 5/15/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 9/9/2004 31 Female 110 lb 5/21/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 38 Female 8/3/2007 Germany
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 6/25/2007 55 Male 9/5/2007 Physician Cayman Islands
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 9/7/2007 United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 10/1/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/11/2007 74 Female 10/11/2007 Consumer Japan
Primary
Concomitant
Vomiting Hospitalization 9/11/2007 74 Female 10/19/2007 Consumer Japan
Primary
Concomitant
Vomiting Hospitalization 9/1/2007 74 Female 11/16/2007 Japan
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 146 lb 2/12/2008 United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1/15/2008 79 Male 212 lb 2/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 146 lb 2/18/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 Male 146 lb 4/8/2008 United Kingdom
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 1/17/2007 Female 182 lb 4/10/2008 United States
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 4/16/2008 Germany
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 5/9/2008 Germany
Primary
Concomitant
Visual Disturbance Hospitalization 5/27/2008 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 1/19/2006 39 Female 6/11/2008 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/3/2008 Physician Japan
Primary
Concomitant
Visual Impairment Hospitalization 3/18/2008 7/8/2008 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 5/16/2008 7/23/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/23/2008 Physician Japan
Primary
Concomitant
Prothrombin Time Shortened Other Serious 6/23/2008 Female 10/31/2008 Physician Japan
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 2/14/2008 Female 326 lb 10/27/2008 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 5/16/2008 11/21/2008 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Shortened Other Serious 6/23/2008 Female 12/9/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatic Necrosis Death 7/28/2008 2/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Necrosis Death 7/28/2008 2/18/2009 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 10/29/2002 Female 3/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 3/2/2007 68 Male 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Catatonia Other Serious 47 Female 5/15/2009 Other Health Professional United States
Primary
Concomitant
Vertigo 10/1/2008 Female 225 lb 6/30/2009 United States
Primary
Concomitant
Catatonia Other Serious 47 Female 7/7/2009 Other Health Professional Japan
Primary
Concomitant
Lactic Acidosis Hospitalization 1/9/2009 60 Female 220 lb 7/28/2009 Physician Germany
Primary
Concomitant
Vomiting Other Serious 2/1/2008 65 Female 8/4/2009 Lawyer United States
Primary
Concomitant
Lactic Acidosis Hospitalization 1/9/2009 60 Female 220 lb 8/31/2009 Physician Germany
Primary
Concomitant
Catatonia Hospitalization 47 Female 9/3/2009 Other Health Professional United States
Primary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 1/9/2009 60 Female 220 lb 10/15/2009 Other Health Professional Germany
Primary
Concomitant
Catatonia Other Serious 47 Female 10/16/2009 Other Health Professional United States
Primary
Concomitant
Catatonia Other Serious 47 Female 10/23/2009 Other Health Professional United States
Primary
Concomitant
Catatonia Other Serious 47 Female 10/26/2009 Other Health Professional Japan
Primary
Concomitant
Catatonia Hospitalization 47 Female 12/10/2009 Other Health Professional United States
Primary
Concomitant
Catatonia Other Serious 47 Female 12/14/2009 Other Health Professional Japan
Primary
Concomitant
Visual Impairment Other Serious 82 Female 1/21/2010 United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2008 69 Male 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/7/2010 United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2008 69 Male 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/24/2008 69 Male 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/24/2008 69 Male 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 3/23/2010 67 Female 118 lb 5/18/2010 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/16/2009 76 Male 176 lb 7/21/2010 Physician Japan
Primary
Concomitant
Splenomegaly Other Serious 2/1/2008 46 Female 143 lb 8/19/2010 Lawyer United States
Primary
Concomitant
Sudden Death Death 3/25/2010 46 Female 97 lb 8/31/2010 Physician China
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/16/2009 76 Male 176 lb 9/20/2010 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2008 46 Female 143 lb 10/12/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/1/2008 46 Female 108 lb 11/29/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 12/7/2010 Physician United States
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 9/15/2010 60 Female 12/8/2010 Physician United States
Primary
Secondary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant
Death Death 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2010 60 Female 12/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Fungal Hospitalization 7/26/2010 51 Male 198 lb 1/3/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 9/15/2010 60 Female 1/10/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/25/2011 Consumer Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Death 3/25/2010 46 Female 97 lb 3/16/2011 Physician China
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 83 Male 3/31/2011 Physician Portugal
Primary
Concomitant
Liver Disorder Death 4/2/2011 84 Male 5/23/2011 Other Health Professional Japan
Primary
Concomitant
Hypotension Death 4/2/2011 84 Male 6/16/2011 Other Health Professional Japan
Primary
Concomitant
Nausea Hospitalization 55 Male 123 lb 6/21/2011 Consumer Germany
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 7/21/2010 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Device Related Infection Other Serious 8/26/2009 66 Female 115 lb 7/20/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Acute Prerenal Failure Hospitalization 6/30/2011 80 Male 93 lb 7/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 8/26/2009 66 Female 115 lb 8/22/2011 Physician Germany
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 6/30/2011 80 Male 93 lb 8/31/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Myoclonus Other Serious 88 Male 9/2/2011 Other Health Professional Japan
Primary
Concomitant
Acute Prerenal Failure Hospitalization 6/30/2011 80 Male 93 lb 9/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 6/30/2011 80 Male 93 lb 10/12/2011 Physician Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 8/10/2011 58 Female 10/13/2011 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 8/10/2011 58 Female 10/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Death 2/1/2008 65 Female 209 lb 10/19/2011 Lawyer United States
Primary
Secondary
Concomitant
Death Death 59 Male 11/4/2011 Physician Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 59 Male 11/28/2011 Physician Sweden
Primary
Concomitant
Interacting
Agranulocytosis Death 5/31/2011 59 Male 12/2/2011 Physician Sweden
Primary
Concomitant
Interacting
Pharyngitis Life Threatening 10/22/2011 83 Female 172 lb 12/23/2011 Physician Japan
Primary
Concomitant
Hypertensive Crisis Hospitalization 8/1/2011 74 Female 110 lb 12/26/2011 Physician Germany
Primary
Secondary
Concomitant
Graft Versus Host Disease In Skin Other Serious 4/22/2010 13 Male 90 lb 1/9/2012 Physician Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 8/1/2011 74 Female 110 lb 1/11/2012 Physician Germany
Primary
Secondary
Concomitant
Anxiety Other Serious 2/1/2008 65 Female 209 lb 1/16/2012 Consumer United States
Primary
Secondary
Concomitant
Clostridium Colitis Hospitalization 6/20/2011 84 Female 1/23/2012 Consumer Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 8/6/2009 77 Female 104 lb 2/10/2012 Physician Japan
Primary
Concomitant
Lung Infiltration Hospitalization 60 Female 99 lb 2/6/2012 Pharmacist Germany
Primary
Concomitant
Rash Maculo-papular Other Serious 66 Female 2/10/2012 Other Health Professional Spain
Primary
Concomitant
Rash Macular Other Serious 66 Female 2/14/2012 Spain
Primary
Concomitant
Cardiac Arrest Hospitalization 2/22/2012 74 Male 179 lb 3/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Back Disorder Hospitalization Male 3/21/2012 Pharmacist United States
Primary
Concomitant
Graft Versus Host Disease In Skin Death 4/20/2010 13 Male 90 lb 3/26/2012 Physician Japan
Primary
Concomitant
Neutropenia Life Threatening 2/22/2012 74 Male 179 lb 3/26/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 3/25/2010 46 Female 97 lb 4/23/2012 Physician China
Primary
Secondary
Concomitant
Death Death Male 5/3/2012 Physician Germany
Primary
Secondary
Concomitant
Death Death 4/14/2012 Male 5/10/2012 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Death 3/25/2010 46 Female 97 lb 5/17/2012 Physician China
Primary
Secondary
Concomitant
Bronchitis Hospitalization Male 5/17/2012 Pharmacist United States
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 1/18/2012 77 Female 108 lb 5/30/2012 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease In Skin Death 4/20/2010 13 Male 90 lb 6/1/2012 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 10/22/2011 83 Female 172 lb 6/4/2012 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 1/18/2012 77 Female 108 lb 6/5/2012 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 8/6/2009 77 Female 104 lb 6/10/2012 Physician Japan
Primary
Concomitant
Rectal Cancer Death 1/5/2012 88 Male 148 lb 6/11/2012 Other Health Professional Belgium
Primary
Secondary
Concomitant
Rectal Cancer Death 1/5/2012 88 Male 148 lb 6/29/2012 Other Health Professional Belgium
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 5/15/2012 49 Female 127 lb 7/6/2012 Physician Hong Kong
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/21/2010 7/9/2012 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/6/2009 77 Female 104 lb 8/1/2012 Physician Japan
Primary
Concomitant
Blood Bilirubin Increased Other Serious 61 Male 8/6/2012 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/29/2012 69 Female 106 lb 8/15/2012 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Acute Death 11/25/2009 84 Female 159 lb 10/23/2012 Other Health Professional De
Primary
Concomitant
Interacting
Weight Increased Hospitalization 7/26/2010 52 Male 198 lb 4/19/2013 Physician Jp
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 6/29/2012 69 Female 106 lb 2/27/2013 Physician Kr
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/21/2011 62 Female 180 lb 9/26/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 4/14/2012 Male 10/19/2012 Physician De
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 9/10/2010 63 Male 2/26/2013 Physician Ua
Primary
Concomitant
Death Death 2/13/2013 68 Male 2/21/2013 Physician Us
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 53 Female 3/7/2013 Physician Jp
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 3/7/2013 68 Female 198 lb 4/2/2013 Pharmacist Us
Primary
Secondary
Concomitant
Allergic Myocarditis Other Serious NotSpecified 3/20/2013 Physician Us
Primary
Secondary
Allergic Myocarditis Other Serious NotSpecified 3/20/2013 Physician Us
Primary
Secondary
Allergic Myocarditis Other Serious NotSpecified 3/20/2013 Physician Us
Primary
Secondary
Ventricular Dysfunction Other Serious 9/10/2010 63 Male 5/16/2013 Other Health Professional Ua
Primary
Secondary
Concomitant
Enterococcal Infection Other Serious 2013 59 Male 146 lb 5/24/2013 Pharmacist Br
Primary
Concomitant
Myocardial Infarction Death 5/16/2013 80 Male 7/18/2013 Physician Us
Primary
Concomitant
Weight Increased Hospitalization 6/3/2013 18 Female 195 lb 6/7/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Diarrhoea 2011 71 Male 2/6/2013 Us
Primary
Concomitant

Drug Data