Levofloxacin combined with Rifampicin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Deafness Bilateral Disability 2/5/2006 Male 3/13/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 90 Male 4/27/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/1/2003 66 Male 4/27/2006 Physician Japan
Primary
Concomitant
Dermatitis Exfoliative Other Serious 90 Male 4/27/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 31 Male 99 lb 5/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/10/2006 27 Male 6/9/2006 Other Health Professional Hungary
Primary
Concomitant
Rhabdomyolysis Hospitalization 5/20/2006 Male 7/12/2006 Other Health Professional Spain
Primary
Concomitant
Tuberculosis Life Threatening 1/1/2003 39 Male 8/22/2006 Spain
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 5/5/2005 20 Male 8/30/2006 Consumer United States
Primary
Secondary
Concomitant
Urine Abnormality Hospitalization 1/10/2006 27 Male 10/6/2006 Other Health Professional Hungary
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/10/2006 27 Male 11/20/2006 Other Health Professional Hungary
Primary
Concomitant
Drug Level Decreased Other Serious 31 Female 3/19/2007
Primary
Concomitant
Interacting
Systemic Lupus Erythematosus Other Serious 31 Female 3/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Melaena Other Serious 9/2/2006 52 Male 4/7/2007 Physician Japan
Primary
Concomitant
Lymph Node Tuberculosis Hospitalization 9/22/2006 Female 126 lb 4/20/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 9/2/2006 52 Male 5/3/2007 Physician Japan
Primary
Concomitant
Respiratory Failure Death 2/5/2007 54 Male 5/30/2007 Physician Japan
Primary
Concomitant
Nephrotic Syndrome Other Serious 4/1/2006 71 Female 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 6/27/2007 Italy
Primary
Concomitant
Nephrotic Syndrome Other Serious 4/1/2006 71 Female 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 7/9/2007 United States
Primary
Secondary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 7/12/2007 Italy
Primary
Concomitant
Pyrexia Other Serious 4/1/2006 77 Female 7/11/2007 Physician Japan
Primary
Secondary
Concomitant
Drug Level Decreased Other Serious 3 Female 7/19/2007 France
Primary
Secondary
Concomitant
Bursitis Infective Hospitalization 5/14/2007 Female 121 lb 8/10/2007 Italy
Primary
Concomitant
Atelectasis Other Serious 9/1/2005 76 Male 8/9/2007 Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 82 Female 8/22/2007
Primary
Secondary
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 60 lb 8/22/2007 United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 9/1/2005 76 Male 8/21/2007 Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 12/28/2006 Female 105 lb 1/4/2007 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 82 Female 8/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Urinary Retention Other Serious 7/15/2005 Male 9/6/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Metabolic Encephalopathy Hospitalization 82 Female 9/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Urinary Retention Other Serious 1/1/2005 78 Male 9/4/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 2/5/2007 54 Male 9/3/2007 Physician Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 60 lb 9/18/2007 United States
Primary
Secondary
Concomitant
Nausea Other Serious 82 Female 9/24/2007
Primary
Secondary
Nausea Other Serious 82 Female 10/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Autoimmune Hepatitis Death 70 Female 10/22/2007 Other Health Professional Japan
Primary
Secondary
Autoimmune Hepatitis Death 70 Female 10/23/2007 Japan
Primary
Secondary
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 60 lb 11/26/2007 United States
Primary
Secondary
Concomitant
Pyroglutamate Increased Hospitalization 1/1/2007 82 Female 12/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Nausea Other Serious 1/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Oxygen Saturation Decreased Hospitalization 9/20/2007 Female 132 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Clostridial Infection Other Serious 72 Male 2/1/2008 Physician United Kingdom
Primary
Secondary
Urine Ketone Body Present Hospitalization 82 Female 4/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Other Serious 10/31/2007 83 Female 4/29/2008 Other Health Professional Japan
Primary
Concomitant
Tuberculosis Hospitalization 5/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 82 Female 6/25/2008 Other Health Professional Japan
Primary
Secondary
Clostridial Infection Other Serious 72 Male 7/17/2008 Physician United Kingdom
Primary
Secondary
Oesophagitis Other Serious 81 Female 9/10/2008 Physician Italy
Primary
Secondary
Concomitant
Urine Ketone Body Present Hospitalization 82 Female 9/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 82 Female 11/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 21 Male 12/16/2008
Primary
Secondary
Concomitant
Tuberculosis Other Serious Male 1/5/2009 Consumer Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Death 1/22/2009 70 Male 2/26/2009 Physician Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 10/29/2002 Female 3/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vesicoureteric Reflux Hospitalization 3/2/2004 Female 4/2/2009 Physician Turkey
Primary
Concomitant
Pancytopenia Hospitalization 65 Male 4/7/2009 Greece
Primary
Concomitant
Hypoglycaemia Death 1/22/2009 70 Male 6/22/2009 Physician Japan
Primary
Concomitant
Tuberculosis Death 24 Female 8/13/2009 Other Health Professional India
Primary
Secondary
Weight Decreased Other Serious 10/1/2009 80 Male 86 lb 12/8/2009 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2009 80 Male 86 lb 1/20/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2009 80 Male 86 lb 1/20/2010 Physician France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2009 80 Male 3/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Post Procedural Infection Other Serious 11/2/2009 80 Male 3/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Impaired Healing Other Serious 11/1/2009 75 Male 3/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 11/25/2008 70 Female 73 lb 3/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Deafness Bilateral Disability 2/5/2006 59 Male 4/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Hospitalization 70 Female 5/17/2010
Primary
Concomitant
Rash Hospitalization 7/1/2006 70 Female 5/27/2010 Japan
Primary
Concomitant
Superinfection Hospitalization 7/1/2006 70 Female 7/15/2010 Physician Japan
Primary
Concomitant
Impaired Healing Other Serious 11/1/2009 75 Male 7/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Post Procedural Infection Other Serious 11/2/2009 80 Male 7/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious 1/25/2008 53 Female 8/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Nocardiosis Other Serious 70 Female 8/26/2010 Other Health Professional Japan
Primary
Concomitant
Peritonitis Hospitalization 8/8/2010 24 Male 9/1/2010 Other Health Professional Philippines
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 75 Female 9/7/2010 Physician Spain
Primary
Secondary
Concomitant
Peritonitis Hospitalization 8/8/2010 24 Male 9/9/2010 Other Health Professional Philippines
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 75 Female 9/17/2010 Physician Spain
Primary
Secondary
Concomitant
Tinnitus Other Serious 40 Female 10/22/2010 Physician India
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 44 Male 12/2/2010 Other Health Professional France
Primary
Secondary
Respiratory Distress Other Serious 44 Male 12/13/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 44 Male 12/15/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 44 Male 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 2/1/2007 57 Male 1/5/2011 Other Health Professional Belgium
Primary
Secondary
Concomitant
Sudden Death Death 68 Male 2/24/2011 Other Health Professional Turkey
Primary
Concomitant
Interacting
Pneumonia Other Serious 7/23/2009 86 Male 6/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 12/15/2010 69 Female 6/13/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 3/14/2011 61 Female 95 lb 6/30/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/23/2009 86 Male 7/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 3/22/2011 61 Female 95 lb 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 3/14/2011 61 Female 95 lb 7/28/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Drug Resistance Other Serious 7/1/2000 19 Female 7/22/2011 Other Health Professional Sweden
Primary
Concomitant
Drug Ineffective For Unapproved Indication Other Serious 1/1/2008 47 Female 98 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Other Serious 1/1/2008 47 Female 98 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 86 Male 106 lb 9/9/2011 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 5/30/2011 40 Male 9/13/2011 Physician France
Primary
Secondary
Concomitant
Diarrhoea Other Serious 68 Male 90 lb 9/13/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Pulmonary Cavitation Other Serious 61 Male 93 lb 9/13/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Scar Other Serious 5/30/2011 74 Male 9/16/2011 Other Health Professional France
Primary
Secondary
Tubulointerstitial Nephritis Other Serious 5/30/2011 74 Male 9/20/2011 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 68 Male 90 lb 9/26/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 3/14/2011 61 Female 95 lb 9/27/2011 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Hospitalization 7/23/2009 86 Male 10/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Eosinophilic Pneumonia Other Serious 9/19/2011 61 Male 243 lb 10/28/2011 Switzerland
Primary
Concomitant
Toxic Skin Eruption Other Serious 75 Male 12/14/2011 Other Health Professional Japan
Primary
Concomitant
Aspergillosis Other Serious 12/16/2011 Greece
Primary
Concomitant
Toxic Skin Eruption Other Serious 75 Male 1/4/2012 Other Health Professional Japan
Primary
Concomitant
Immunosuppression Hospitalization 1/17/2012 Greece
Primary
Concomitant
Diarrhoea Other Serious 11/25/2011 88 Female 1/27/2012 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 70 Male 1/31/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/30/2011 83 Male 110 lb 2/6/2012 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 12/28/2011 79 Male 117 lb 2/28/2012 Physician Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 6/23/2011 77 Female 3/20/2012 Physician France
Primary
Secondary
Rash Other Serious 5/1/2010 56 Female 5/2/2012 Other Health Professional Japan
Primary
Secondary
Pyrexia Other Serious 8/30/2011 83 Male 110 lb 5/24/2012 Physician Japan
Primary
Concomitant
Decreased Appetite Hospitalization 55 Male 6/5/2012 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 12/28/2011 79 Male 117 lb 6/14/2012 Other Health Professional Japan
Primary
Concomitant
Alopecia Other Serious 5/1/2010 56 Female 7/2/2012 Other Health Professional Japan
Primary
Secondary
Decreased Appetite Hospitalization 4/1/2011 55 Male 7/5/2012 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 5/28/2012 Male 7/19/2012 Other Health Professional Italy
Primary
Concomitant
Drug Level Decreased Other Serious 29 Female 7/20/2012 Other Health Professional Spain
Primary
Concomitant
Interacting
Rash Other Serious 5/2010 56 Female 9/4/2012 Country Not Specified
Primary
Secondary
Concomitant
Vomiting Hospitalization 2011 Female 77 lb 11/22/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1997 Male 11/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Vomiting Other Serious 7/2010 56 Female 11/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 31 Male 12/3/2012 Physician Jp
Primary
Secondary
Rash Macular Hospitalization 26 Female 12/10/2012 Other Health Professional Kr
Primary
Secondary
Concomitant
Pulmonary Cavitation Death 2/2008 58 Male 1/7/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 8/2010 56 Female 1/9/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/7/2010 56 Female 1/15/2013 Other Health Professional Jp
Primary
Secondary
Hypersensitivity Other Serious 56 Female 1/11/2013 Other Health Professional Jp
Primary
Secondary
Rash Maculo-papular Other Serious 31 Male 1/15/2013 Other Health Professional Jp
Primary
Secondary
Drug Reaction With Eosinophilia And Systemic Symptoms Other Serious 31 Male 1/17/2013 Physician Jp
Primary
Secondary
Paradoxical Drug Reaction Other Serious 4 Male 3/1/2013 Other Health Professional Ci
Primary
Secondary
Off Label Use Other Serious 4 NotSpecified 3/2/2013 Other Health Professional Ci
Primary
Secondary
Drug Reaction With Eosinophilia And Systemic Symptoms Other Serious 6/15/2012 27 Male 4/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Treatment Failure Death 2 Male 5/14/2013 Other Health Professional Gr
Primary
Secondary
Hepatic Failure Hospitalization 2 Male 5/15/2013 Other Health Professional Gr
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 5/26/2011 68 Female 84 lb 5/24/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Tuberculosis Other Serious 5/2006 51 Male 7/10/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Pneumonia Legionella Other Serious 53 Female 6/28/2013 Physician Us
Primary
Secondary
Vomiting Hospitalization 43 Male 142 lb 8/5/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 15 Female 8/15/2013 Other Health Professional In
Primary
Secondary
Concomitant
Pyrexia Hospitalization 67 Female 84 lb 8/15/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Drug Resistance Hospitalization 60 Male 11/12/2013 Other Health Professional Jp
Primary
Secondary
Jaundice Other Serious 57 Male 10/29/2013 Other Health Professional Es
Primary
Secondary
Weight Decreased Other Serious 57 Male 11/19/2013 Physician Es
Primary
Secondary

Drug Data