Levofloxacin combined with Metronidazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Embolism Other Serious 42 Male 1/10/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/29/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 10/18/2004 54 9/16/2005 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death 11/18/2005 24 Male 212 lb 2/10/2006 Physician United States
Primary
Secondary
Ventricular Dysfunction Other Serious 1/1/2000 Female 220 lb 4/24/2006 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 11/6/2005 44 Male 11/9/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Decreased Life Threatening 1/31/2006 29 Female 2/14/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 45 Female 165 lb 5/22/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/1/2004 Male 7/14/2006 Consumer United States
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Other Serious 84 Male 7/7/2006 Physician United Kingdom
Primary
Concomitant
Stenotrophomonas Infection Other Serious 1/1/2005 74 Female 7/19/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/14/2005 63 Male 8/15/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 12/7/2004 68 Female 199 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Required Intervention 28 Male 9/15/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/23/2006 Male 154 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 28 Male 9/27/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/9/2004 55 Female 10/20/2006 United States
Primary
Concomitant
Stenotrophomonas Infection Other Serious 1/1/2005 74 Female 10/19/2006 Physician United States
Primary
Concomitant
Pyrexia Other Serious 5/18/2006 78 Female 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3/15/2006 75 Female 11/15/2006 Pharmacist United States
Primary
Concomitant
Leukopenia Death 5/14/2006 69 Male 132 lb 12/13/2006 Korea, Republic Of
Primary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 9/1/2006 76 Female 134 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 3/6/2007 45 Male 165 lb 3/19/2007 Other Health Professional United States
Primary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/27/2007 51 Female 463 lb 5/10/2007 Consumer United States
Primary
Concomitant
Septic Shock Death 65 Male 6/19/2007 Physician United States
Primary
Secondary
Septic Shock Other Serious 65 Male 6/29/2007 United States
Primary
Secondary
Rash Hospitalization 4/13/2007 63 Male 181 lb 4/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Palpitations Other Serious 7/1/2007 63 Female 8/7/2007 Canada
Primary
Concomitant
Urine Abnormality Other Serious 53 Male 7/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Palpitations Other Serious 7/1/2007 63 Female 8/13/2007 Canada
Primary
Concomitant
Pyrexia Hospitalization 6/27/2007 Male 146 lb 8/14/2007 Italy
Primary
Concomitant
Myocardial Infarction Hospitalization 1 Male 8/22/2007
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1 Male 8/23/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 1 Male 8/27/2007 United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 1/30/2007 Male 225 lb 2/2/2007 United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Required Intervention 6/1/2007 48 Female 6/8/2007 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1 Male 8/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 7/12/2007 39 Male 8/21/2007 Physician United States
Primary
Secondary
Concomitant
Metabolic Acidosis Death 53 Male 8/21/2007 United Kingdom
Primary
Secondary
Tumour Invasion Other Serious 7/1/2007 63 Female 8/30/2007 Canada
Primary
Concomitant
Urine Abnormality Other Serious 1 Male 8/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 53 Male 9/7/2007
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 53 Male 9/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/1/2007 63 Female 9/13/2007 Canada
Primary
Concomitant
Myocardial Infarction Other Serious 53 Male 9/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 53 Male 9/20/2007 United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/20/2006 68 Female 154 lb 9/13/2007 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 53 Male 9/24/2007
Primary
Secondary
Concomitant
Myocardial Infarction Death 53 Male 9/24/2007 United Kingdom
Primary
Secondary
Concomitant
Urine Abnormality Other Serious 53 Male 9/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 53 Male 9/27/2007 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 53 Male 9/28/2007 United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 53 Male 9/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 53 Male 9/27/2007
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 53 Male 10/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Death 53 Male 10/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Urine Amino Acid Level Increased Other Serious 53 Male 10/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Myocardial Infarction Hospitalization 53 Male 10/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/11/2007 48 Female 10/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 53 Male 11/12/2007 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Staphylococcal Infection Other Serious 21 Male 12/3/2007 Other Health Professional Greece
Primary
Secondary
Pyroglutamate Increased 1/1/2007 53 Male 12/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 78 Female 187 lb 4/16/2008 Pharmacist United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 4/22/2008 82 Female 172 lb 5/2/2008 United States
Primary
Concomitant
Linear Iga Disease Other Serious 61 Female 8/1/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 70 Male 8/1/2008 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 7/12/2007 39 Male 8/20/2008 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Hospitalization 78 Female 187 lb 8/28/2008 Other Health Professional Japan
Primary
Concomitant
Interacting
Sepsis Death 22 Male 8/28/2008 Pharmacist United States
Primary
Concomitant
Leukopenia Death 9/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/23/2008 82 Male 237 lb 10/30/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/23/2008 82 Male 237 lb 10/31/2008 Physician United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 10/1/2008 44 Female 10/24/2008 Pharmacist United States
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Vulval Abscess Hospitalization 5/22/2006 Female 187 lb 11/26/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 52 Male 11/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 53 Male 12/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Vulval Abscess Other Serious 5/22/2006 Female 187 lb 12/18/2008 United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/2/2008 15 Male 166 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 2/6/2008 14 Female 97 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Systemic Candida Other Serious 10/30/2008 60 Female 115 lb 1/23/2009 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Deafness Neurosensory Hospitalization 51 Female 3/26/2009 Other Health Professional United States
Primary
Concomitant
Refusal Of Treatment By Relative Hospitalization 1/3/2009 81 Female 119 lb 3/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 3/8/2009 45 Male 134 lb 4/15/2009 Consumer United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/9/2007 4/17/2009 Physician Egypt
Primary
Concomitant
Pneumonia Aspiration Hospitalization 3/8/2009 Male 134 lb 4/16/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 3/8/2009 45 Male 134 lb 4/27/2009 Consumer United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/9/2007 5/4/2009 Physician Egypt
Primary
Concomitant
Ureteric Stenosis Hospitalization 11/4/2003 Female 83 lb 6/23/2009 Physician Brazil
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 Female 196 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 81 Male 6/26/2009 Canada
Primary
Concomitant
Interacting
Ureteric Stenosis Hospitalization 11/4/2003 Female 7/1/2009 Physician Brazil
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 81 Male 7/9/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Tachycardia Hospitalization 81 Male 7/9/2009
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 81 Male 7/13/2009 Physician Canada
Primary
Concomitant
Interacting
Agranulocytosis Life Threatening 5/24/2009 76 Male 198 lb 7/10/2009 Pharmacist United States
Primary
Concomitant
Drug Interaction Hospitalization 72 Female 176 lb 7/20/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/30/2009 Female 7/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 52 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/30/2009 Female 8/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 52 Female 8/5/2009 Lawyer United States
Primary
Concomitant
Respiratory Rate Increased Disability 8/26/2009 78 Female 96 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Toxic Encephalopathy Other Serious 66 Female 9/25/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious 5/20/2009 19 Male 146 lb 9/16/2009 Physician India
Primary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Serum Sickness Other Serious 5/20/2009 19 Male 146 lb 10/1/2009 Physician India
Primary
Concomitant
Thrombosis Life Threatening 6/23/2008 82 Male 238 lb 10/16/2009 Physician United States
Primary
Secondary
Concomitant
Transfusion Other Serious 1/1/2004 Male 11/5/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/23/2008 82 Male 238 lb 11/6/2009 Physician United States
Primary
Concomitant
Transfusion Other Serious 1/1/2004 Male 11/16/2009 Other Health Professional United States
Primary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 55 Male 11/24/2009 United States
Primary
Concomitant
Renal Failure Other Serious 2/13/2007 61 Male 214 lb 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Transfusion Other Serious 1/1/2004 Male 12/10/2009 Other Health Professional United States
Primary
Concomitant
Pancytopenia Death 12/14/2009 72 Female 211 lb 1/8/2010 Pharmacist United States
Primary
Concomitant
Large Intestinal Ulcer Hospitalization 11/18/2009 65 Female 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 53 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 158 lb 2/12/2010 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/4/2005 66 Male 159 lb 2/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Stress Cardiomyopathy Life Threatening 3/4/2005 66 Male 158 lb 2/18/2010 Physician Belgium
Primary
Secondary
Concomitant
Transfusion Other Serious 1/1/2004 Male 2/26/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 10/1/2007 61 Male 214 lb 3/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/1995 Male 205 lb 3/4/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 75 Male 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 2/4/2009 72 Female 3/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Vomiting Other Serious 75 Male 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/2/2010 78 Female 113 lb 3/15/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 75 Male 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 2/4/2009 72 Female 5/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Urosepsis Hospitalization 2/4/2009 72 Female 5/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 1/1/2009 61 Female 6/15/2010 Physician Germany
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/22/2010 United States
Primary
Secondary
Concomitant
Depression 36 Female 6/29/2010 Consumer United States
Primary
Secondary
Concomitant

Drug Data