Levofloxacin combined with Loxonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Drug Interaction Hospitalization 3/16/2005 Female 84 lb 5/30/2006 Other Health Professional Japan
Primary
Interacting
Drug Interaction Hospitalization 3/16/2005 Female 84 lb 6/23/2006 Other Health Professional Japan
Primary
Interacting
Transaminases Increased Hospitalization 9/20/2006 62 Male 10/20/2006 Physician Japan
Primary
Secondary
Concomitant
Myoglobin Urine Present Other Serious 9/7/2006 74 Male 10/30/2006 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization Female 11/8/2006 Other Health Professional Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization Female 11/22/2006 Other Health Professional Japan
Primary
Concomitant
Status Epilepticus Hospitalization 10/11/2006 Female 97 lb 12/5/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 12/8/2006 Male 71 lb 1/3/2007 Other Health Professional Japan
Primary
Concomitant
Pneumonia Other Serious 6/28/2006 Female 108 lb 2/15/2007 Physician Japan
Primary
Concomitant
Urinary Retention Other Serious 12/1/2006 Male 187 lb 3/9/2007 Physician Japan
Primary
Secondary
Concomitant
Shock Hospitalization 8/15/2006 Female 3/21/2007 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/4/2007 48 Male 4/20/2007 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 4/4/2007 48 Male 4/27/2007 Physician Japan
Primary
Secondary
Wound Infection Hospitalization 10/23/2006 52 Male 143 lb 5/29/2007 Physician Japan
Primary
Concomitant
Pigmentation Disorder Other Serious 5/1/2007 Female 6/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Erythema Multiforme Life Threatening 5/15/2007 80 Female 106 lb 6/8/2007 Physician Japan
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 5/23/2007 64 Male 6/8/2007 Consumer Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/4/2007 Male 6/11/2007 Physician Japan
Primary
Secondary
Pigmentation Disorder Other Serious 5/1/2007 Female 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 5/25/2007 83 Male 6/22/2007 Physician Japan
Primary
Concomitant
Erythema Multiforme Life Threatening 5/1/2007 80 Female 106 lb 6/22/2007 Physician Japan
Primary
Concomitant
Hypoaesthesia Hospitalization 6/1/2007 Male 6/26/2007 Physician Switzerland
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/23/2007 64 Male 117 lb 7/3/2007 Consumer Japan
Primary
Concomitant
Stress Hospitalization 6/1/2007 Male 7/10/2007 Physician Switzerland
Primary
Concomitant
Pneumonitis Hospitalization 6/5/2007 63 Male 7/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pigmentation Disorder Other Serious 5/1/2007 Female 7/13/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Erythema Multiforme Life Threatening 5/1/2007 80 Female 106 lb 7/16/2007 Physician Japan
Primary
Concomitant
Metrorrhagia Hospitalization 6/14/2007 Female 7/19/2007 Physician Japan
Primary
Secondary
Pneumonitis Hospitalization 6/5/2007 63 Male 7/23/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6/5/2007 63 Male 7/31/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Metrorrhagia Hospitalization 6/14/2007 Female 8/8/2007 Physician Japan
Primary
Secondary
Blood Pressure Decreased Disability 6/4/2007 Male 8/10/2007 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/29/2006 Female 93 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 58 Male 146 lb 8/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 58 Male 146 lb 8/30/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 10/27/2005 58 Male 146 lb 9/25/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/26/2007 Male 10/1/2007 Other Health Professional Japan
Primary
Secondary
Pyrexia Other Serious 8/26/2007 Male 10/2/2007 Other Health Professional Japan
Primary
Secondary
Post Procedural Infection Hospitalization 10/23/2006 52 Male 143 lb 9/28/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 9/26/2007 61 Female 10/5/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Encephalopathy Other Serious 2/14/2007 53 Male 10/8/2007 Physician Japan
Primary
Concomitant
Heart Rate Decreased Other Serious 2/6/2006 76 Male 112 lb 10/9/2007 Other Health Professional Japan
Primary
Concomitant
Heart Rate Decreased Other Serious 2/6/2006 76 Male 112 lb 10/10/2007 Other Health Professional Japan
Primary
Concomitant
Heart Rate Decreased Other Serious 2/6/2006 76 Male 112 lb 10/11/2007 Other Health Professional Japan
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 2/6/2006 76 Male 112 lb 10/15/2007 Other Health Professional Japan
Primary
Concomitant
Pyrexia Other Serious 5/12/2006 28 Male 117 lb 10/17/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/26/2007 Male 10/19/2007 Other Health Professional Japan
Primary
Secondary
Lung Disorder Hospitalization 10/4/2007 70 Male 10/19/2007 Other Health Professional Japan
Primary
Secondary
Rhabdomyolysis Other Serious 8/26/2007 Male 10/19/2007 Other Health Professional Japan
Primary
Secondary
Stomatitis Other Serious 5/12/2006 28 Male 117 lb 10/19/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/12/2006 28 Male 117 lb 10/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 50 Female 10/23/2007 Other Health Professional Japan
Primary
Secondary
Ventricular Extrasystoles Other Serious 2/6/2006 76 Male 112 lb 10/25/2007 Other Health Professional Japan
Primary
Concomitant
Anosmia Other Serious 11/14/2007 68 Female 4/21/2008 Physician Japan
Primary
Secondary
Cardiac Failure Congestive Disability 4/16/2007 46 Female 108 lb 4/22/2008 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Death 12/7/2006 72 Male 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 5/28/2008 69 Male 134 lb 6/30/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/3/2008 Physician Japan
Primary
Concomitant
Acquired Haemophilia Hospitalization 5/7/2008 62 Male 7/7/2008 Other Health Professional Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/23/2008 46 Male 7/8/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Acquired Haemophilia Hospitalization 5/7/2008 Male 7/11/2008 Other Health Professional Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 5/20/2008 Male 7/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/23/2008 Physician Japan
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 5/7/2008 Male 8/1/2008 Other Health Professional Japan
Primary
Concomitant
Visual Impairment Hospitalization 4/27/2009 62 Male 168 lb 5/14/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 4/27/2009 62 Male 168 lb 5/26/2009 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/1/2008 Male 8/25/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 12/15/2008 68 8/25/2009 Physician Japan
Primary
Secondary
Concomitant
Dehydration Other Serious 7/23/2009 Female 8/26/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonitis Other Serious 4/18/2009 65 9/7/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 5/14/2009 52 Male 9/15/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 7/23/2007 Male 161 lb 9/16/2009 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious 1/1/2008 Female 9/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonitis Other Serious 4/18/2009 65 9/18/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 5/14/2009 Male 9/16/2009 Other Health Professional Japan
Primary
Concomitant
Blood Pressure Increased Hospitalization 11/2/2009 Female 3/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 2/1/2010 Male 3/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Facial Spasm Other Serious Male 3/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 5/14/2009 52 Male 3/23/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 11/25/2008 70 Female 73 lb 3/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Headache Hospitalization 5/24/2008 Male 150 lb 3/25/2010 Physician Japan
Primary
Concomitant
Peritonitis Disability 8/17/2009 75 Female 97 lb 4/27/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 7/16/2010 27 Female 8/13/2010 Other Health Professional Japan
Primary
Secondary
Liver Disorder Hospitalization 7/16/2010 27 Female 9/1/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/26/2010 72 Female 10/20/2010 Other Health Professional Japan
Primary
Concomitant
Fungaemia Death 6/22/2005 46 Male 126 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Fungal Death Male 139 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Eosinophilia Hospitalization 9/4/2010 76 Male 12/28/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/1/2008 72 Male 3/7/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 6/22/2010 56 Female 5/9/2011 Consumer Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 6/22/2010 56 Female 5/9/2011 Other Health Professional Japan
Primary
Secondary
Pneumonia Hospitalization 6/11/2010 65 Female 101 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Ulcerative Keratitis Other Serious 1/1/2011 86 Female 5/25/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Death 8/21/2010 48 Female 95 lb 6/2/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Death 6/19/2008 77 Male 134 lb 6/4/2011 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 12/3/2010 58 Male 6/13/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Delirium Other Serious 90 Female 6/20/2011 Other Health Professional Japan
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 6/6/2011 64 Male 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 3/18/2011 71 Male 6/28/2011 Physician Japan
Primary
Concomitant
Convulsion Hospitalization 6/23/2011 45 Male 7/5/2011 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Hospitalization 1/11/2011 71 Male 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Systolic Decreased Hospitalization 6/23/2011 45 Male 7/12/2011 Physician Japan
Primary
Concomitant
Pneumonia Life Threatening 3/18/2011 71 Male 7/12/2011 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 6/15/2011 62 Male 126 lb 7/12/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/14/2009 52 Male 7/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 7/18/2011 Consumer Switzerland
Primary
Concomitant
Respiratory Tract Infection Other Serious 3/3/2011 61 Female 7/20/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Decreased Other Serious 7/23/2007 52 Male 161 lb 7/21/2011 Physician Japan
Primary
Concomitant
Drug Hypersensitivity Hospitalization 6/23/2011 45 Male 7/21/2011 Physician Japan
Primary
Concomitant
Renal Impairment Death 3/18/2011 71 Male 7/21/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 6/6/2011 64 Male 7/26/2011 Physician Japan
Primary
Secondary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 7/27/2011 Other Health Professional Switzerland
Primary
Concomitant
Shock Hospitalization 6/23/2011 45 Male 8/1/2011 Physician Japan
Primary
Concomitant
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Fungaemia Death 6/22/2005 46 Male 126 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/29/2009 60 Female 126 lb 8/3/2011 Physician Japan
Primary
Concomitant
Skin Disorder Other Serious 7/1/2011 72 Male 8/3/2011 Pharmacist Japan
Primary
Concomitant
Pneumonia Other Serious 5/6/2011 76 Female 8/4/2011 Other Health Professional Japan
Primary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 132 lb 8/4/2011 Physician Switzerland
Primary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 8/5/2011 Consumer Switzerland
Primary
Concomitant
Retinal Pigment Epithelial Tear Other Serious 3/4/2011 82 Male 132 lb 8/5/2011 Physician Switzerland
Primary
Concomitant
Ulcerative Keratitis Other Serious 1/1/2011 86 Female 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6/22/2010 56 Female 130 lb 8/11/2011 Physician Japan
Primary
Secondary
Pneumonia Hospitalization 8/11/2011 61 Male 117 lb 8/18/2011 Physician Japan
Primary
Concomitant
Death Death Female 132 lb 8/25/2011 Physician Japan
Primary
Concomitant
Dyspnoea Other Serious 6/22/2010 56 Female 8/29/2011 Physician Japan
Primary
Secondary
Bronchitis Other Serious 6/22/2010 56 Female 8/29/2011 Other Health Professional Japan
Primary
Secondary
Platelet Count Decreased Other Serious 8/13/2010 65 Female 8/30/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/11/2011 61 Male 117 lb 8/31/2011 Physician Japan
Primary
Concomitant
Infection Death 8/21/2010 48 Female 95 lb 9/1/2011 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 56 Female 9/2/2011 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 8/11/2011 61 Male 117 lb 9/8/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 8/11/2011 61 Male 117 lb 9/22/2011 Physician Japan
Primary
Concomitant
Conjunctival Oedema Disability 9/7/2011 22 Female 9/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Conjunctival Oedema 9/7/2011 22 Female 10/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ovarian Cancer Recurrent Death Female 132 lb 10/5/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 2/4/2011 43 Female 154 lb 10/7/2011 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/21/2009 60 Female 126 lb 10/11/2011 Physician Japan
Primary
Concomitant
Speech Disorder Other Serious 8/4/2011 88 Female 10/12/2011 Other Health Professional Japan
Primary
Concomitant
Exposed Bone In Jaw Hospitalization 9/21/2010 54 Female 10/14/2011 Other Health Professional Japan
Primary
Concomitant
Sepsis Other Serious 3/3/2011 61 Female 10/18/2011 Consumer Japan
Primary
Secondary
Concomitant
Delirium Other Serious 8/4/2011 88 Female 10/24/2011 Other Health Professional Japan
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 4/21/2011 75 Female 10/28/2011 Other Health Professional Japan
Primary
Concomitant
Erythema Other Serious 7/17/2011 72 Male 11/2/2011 Pharmacist Japan
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 4/21/2011 75 Female 11/8/2011 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 9/21/2010 54 Female 11/9/2011 Other Health Professional Japan
Primary
Concomitant
Aphthous Stomatitis Hospitalization 9/15/2011 84 Male 11/18/2011 Physician Japan
Primary
Secondary
Pyrexia Hospitalization 9/15/2011 84 Male 11/28/2011 Physician Japan
Primary
Secondary
Sjogren's Syndrome Other Serious 9/15/2011 84 Male 12/1/2011 Physician Japan
Primary
Secondary
Drug Eruption Other Serious 63 Male 12/2/2011 Other Health Professional Japan
Primary
Secondary

Drug Data