Levetiracetam combined with Zonisamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Convulsion Hospitalization 4/27/2008 45 Female 150 lb 5/14/2008 Pharmacist United States
Primary
Concomitant
Pco2 Decreased Required Intervention 2/1/2008 47 Female 120 lb 10/7/2008 United States
Primary
Concomitant
Onycholysis Other Serious 56 Female 12/26/2008 Consumer United States
Primary
Concomitant
Onycholysis Other Serious 56 Female 1/22/2009 Consumer United States
Primary
Concomitant
Temperature Intolerance Hospitalization 9/1/2008 50 Female 119 lb 2/12/2009 United Kingdom
Primary
Concomitant
Grand Mal Convulsion Other Serious 2/27/2009 3 Male 35 lb 2/27/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/29/2009 16 Female 2/26/2009 Other Health Professional United States
Primary
Concomitant
Sudden Unexplained Death In Epilepsy Death 3/9/2009 Female 3/23/2009 Germany
Primary
Concomitant
Respiratory Arrest Required Intervention 2/1/2008 47 Female 120 lb 4/15/2009 United States
Primary
Concomitant
Convulsion Other Serious Female 5/7/2009 United States
Primary
Secondary
Convulsion Other Serious 4/1/2009 Female 5/8/2009 United States
Primary
Secondary
Convulsion Other Serious 4/1/2009 Female 5/8/2009 Physician United States
Primary
Secondary
Convulsion Other Serious Female 5/7/2009 Physician United States
Primary
Secondary
Eye Movement Disorder Other Serious 3/27/2009 55 Male 225 lb 6/10/2009 Lawyer United States
Primary
Concomitant
Headache Other Serious 6/14/2009 47 Male 214 lb 6/24/2009 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2009 44 Male 137 lb 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Product Substitution Issue Hospitalization 1/1/1999 45 Male 190 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 6/2/2009 44 Male 137 lb 8/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Product Substitution Issue Disability 1/1/2002 40 Male 295 lb 8/17/2009 Consumer United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 20 Female 8/24/2009 Physician Germany
Primary
Secondary
Cerebral Atrophy Other Serious 20 Female 9/18/2009 Other Health Professional Germany
Primary
Concomitant
Convulsion Other Serious Female 10/20/2009 Consumer United States
Primary
Secondary
Weight Decreased Life Threatening 1/1/2004 Female 120 lb 11/30/2009 United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 12/11/2009 United States
Primary
Concomitant
Convulsion 6/1/2009 Male 210 lb 11/19/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Colic Hospitalization 1/8/2010 Male 112 lb 1/25/2010 Poland
Primary
Concomitant
Ureteric Dilatation Hospitalization 1/8/2010 Male 112 lb 2/1/2010 Poland
Primary
Concomitant
Renal Colic Hospitalization 1/8/2010 Male 104 lb 2/12/2010 Poland
Primary
Concomitant
Grand Mal Convulsion Hospitalization 46 Female 1/27/2010 Physician Germany
Primary
Concomitant
Myocardial Infarction Life Threatening 12/8/2009 Female 161 lb 2/24/2010 United States
Primary
Concomitant
Renal Colic Hospitalization 1/8/2010 Male 104 lb 3/3/2010 Poland
Primary
Concomitant
Lethargy Other Serious 12/16/2009 27 Female 119 lb 3/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Colic Hospitalization 1/8/2010 Male 104 lb 3/17/2010 Poland
Primary
Concomitant
Renal Colic Hospitalization 1/8/2010 Male 104 lb 3/22/2010 Poland
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 45 Female 123 lb 4/19/2010 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 4/3/2010 57 Male 114 lb 4/16/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Fatigue Other Serious 27 Female 4/27/2010 Austria
Primary
Concomitant
Vertigo Other Serious 29 Male 4/27/2010 Austria
Primary
Concomitant
Convulsion Death Female 101 lb 5/28/2010 Other Health Professional Singapore
Primary
Concomitant
Convulsion Death Female 101 lb 7/6/2010 Other Health Professional Singapore
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 45 Female 123 lb 7/7/2010 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 27 Female 7/14/2010 Ireland
Primary
Secondary
Concomitant
Weight Decreased Death Female 93 lb 7/23/2010 Other Health Professional Singapore
Primary
Concomitant
Thrombophlebitis Hospitalization 6/7/2010 21 Female 7/23/2010 Pharmacist Ireland
Primary
Concomitant
Hyperammonaemic Encephalopathy Other Serious 5 Male 9/9/2010
Primary
Secondary
Suicide Attempt Other Serious 6/17/2010 25 Female 8/19/2010 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 27 Female 9/29/2010 Ireland
Primary
Secondary
Concomitant
Generalised Anxiety Disorder Hospitalization 7/1/2009 24 Female 11/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 8/21/2007 37 Female 154 lb 1/14/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Psychomotor Retardation Hospitalization 7/21/2007 37 Female 129 lb 1/31/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Speech Disorder Other Serious 21 Female 2/2/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 21 Female 2/4/2011 United Kingdom
Primary
Secondary
Concomitant
Depression Disability 5/1/2007 22 Female 2/25/2011 Physician Germany
Primary
Secondary
Dysarthria Hospitalization 22 Female 2/23/2011 Germany
Primary
Secondary
Quadriparesis Other Serious 74 Female 3/14/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Balance Disorder Other Serious 37 Female 3/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Diplopia Other Serious 37 Female 3/28/2011 United Kingdom
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious Female 4/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Status Epilepticus Hospitalization 3/24/2011 56 Male 172 lb 4/18/2011 Physician Italy
Primary
Secondary
Drug Ineffective Other Serious 27 Female 5/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Brain Herniation Other Serious 27 Female 4/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Encephalocele Other Serious 27 Female 4/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Ineffective Other Serious 27 Female 4/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Encephalocele Other Serious 27 Female 5/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 27 Female 5/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 27 Female 5/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Dizziness Male 5/3/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Other Serious 5/20/2011 Female 6/8/2011 Consumer United Kingdom
Primary
Concomitant
Grand Mal Convulsion Hospitalization 12 Male 8/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 12 Male 8/5/2011 Other Health Professional United States
Primary
Concomitant
Sedation Hospitalization 6/6/2010 58 Female 8/10/2011 Consumer United States
Primary
Concomitant
Fatigue Hospitalization 12 Male 8/12/2011 Physician United States
Primary
Secondary
Concomitant
Communication Disorder Other Serious 15 Male 8/15/2011 Physician Germany
Primary
Secondary
Concomitant
Fall Other Serious 12 Male 8/23/2011 Other Health Professional United States
Primary
Concomitant
Fatigue Hospitalization 12 Male 8/25/2011 Other Health Professional United States
Primary
Secondary
Fatigue Hospitalization 12 Male 8/25/2011 Other Health Professional United States
Primary
Secondary
Fatigue Hospitalization 12 Male 8/25/2011 Other Health Professional United States
Primary
Secondary
Complex Partial Seizures Hospitalization 12 Male 8/29/2011 Other Health Professional United States
Primary
Concomitant
Muscle Twitching Hospitalization 12 Male 9/1/2011 Other Health Professional United States
Primary
Secondary
Fatigue Hospitalization 12 Male 9/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 12 Male 9/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Major Depression Hospitalization 11/10/2008 46 Female 8/8/2011 Consumer United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 12 Male 9/8/2011 Other Health Professional United States
Primary
Concomitant
Hyperventilation Other Serious 39 Male 9/16/2011 Other Health Professional Turkey
Primary
Secondary
Dizziness Other Serious 39 Male 9/16/2011 Other Health Professional Turkey
Primary
Secondary
Myoclonus Other Serious 12 Male 9/20/2011 Physician United States
Primary
Secondary
Delusional Disorder, Persecutory Type Disability 7/1/2011 27 Male 10/31/2011 Physician United Kingdom
Primary
Concomitant
Renal Colic Hospitalization 1/8/2010 13 Male 104 lb 11/7/2011 Physician Poland
Primary
Concomitant
Irritability Other Serious 2/21/2010 27 Female 11/14/2011 Consumer United States
Primary
Concomitant
Suicidal Ideation Hospitalization 1/14/2003 34 Male 11/21/2011 Consumer United States
Primary
Concomitant
Somnolence Other Serious 2/14/2009 42 Female 11/23/2011 Consumer United States
Primary
Concomitant
Menstruation Irregular 1/12/2012 19 Female 135 lb 1/17/2012 Consumer United States
Primary
Concomitant
Menstruation Irregular 1/12/2012 19 Female 135 lb 1/23/2012 Consumer United States
Primary
Concomitant
Menstruation Irregular 1/12/2012 19 Female 135 lb 2/2/2012 Consumer United States
Primary
Concomitant
Convulsion Other Serious 21 Female 2/7/2012 Other Health Professional United States
Primary
Secondary
Memory Impairment Hospitalization 1/10/2000 15 Female 12/13/2011 Consumer United States
Primary
Concomitant
Myoclonic Epilepsy Hospitalization 4/23/2011 6 Male 12/13/2011 United States
Primary
Concomitant
Hypotension Other Serious 2/20/2012 61 Female 172 lb 3/15/2012 Consumer United States
Primary
Secondary
Concomitant
Injection Site Rash Other Serious 1/1/2010 53 Female 8/18/2011 Physician United States
Primary
Concomitant
Ecchymosis Other Serious 1/1/2010 53 Female 8/18/2011 Physician United States
Primary
Concomitant
Death Other Serious 3/5/2012 90 Female 3/22/2012 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Other Serious 53 Female 5/18/2011 Physician United States
Primary
Concomitant
Injection Site Erythema Other Serious 53 Female 5/18/2011 Physician United States
Primary
Concomitant
Brain Operation Hospitalization 56 Female 4/9/2012 Consumer United States
Primary
Concomitant
Calculus Urinary Other Serious 6 Female 4/17/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Partial Seizures Other Serious 31 Female 6/20/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Protrusion Tongue Other Serious 31 Female 7/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 31 Female 7/13/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 8/2/2011 52 Male 237 lb 4/4/2012 Consumer United States
Primary
Concomitant
Partial Seizures Other Serious 31 Female 7/10/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Movement Disorder Other Serious 31 Female 7/10/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 31 Female 7/10/2012 Consumer United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 31 Female 7/10/2012 Other Health Professional
Primary
Secondary
Concomitant
Nephrolithiasis Other Serious 6/1/2012 38 Male 7/31/2012 Physician United Kingdom
Primary
Concomitant
Convulsion Other Serious 24 Male 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 17 Female 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Atonic Seizures Other Serious 17 Female 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Atonic Seizures Other Serious 24 Male 8/16/2012 Physician Japan
Primary
Secondary
Concomitant
Drop Attacks Other Serious Female 8/6/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 31 Female 7/31/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 78 Female 12/19/2012 Consumer Us
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 24 Male 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 17 Female 10/16/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Head Injury Other Serious Female 8/16/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 9/4/2012 Physician Jp
Primary
Concomitant
No Therapeutic Response Other Serious 0 9/28/2012 Physician Es
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious Female 10/23/2012 Physician De
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 19 Female 10/25/2012 Other Health Professional Us
Primary
Concomitant
Impaired Work Ability Other Serious 40 Male 11/29/2012 Physician Se
Primary
Concomitant
Off Label Use Other Serious 25 Male 12/4/2012 Physician Us
Primary
Secondary
Status Epilepticus Hospitalization 9 Male 60 lb 12/6/2012 Other Health Professional Jp
Primary
Concomitant
Drug Resistance Other Serious 25 Male 12/12/2012 Physician Us
Primary
Secondary
Urinary Hesitation 12/2012 30 Female 2/5/2013 Other Health Professional Sk
Primary
Concomitant
Fall Hospitalization 1/5/2013 60 Male 134 lb 2/6/2013 Physician Kr
Primary
Concomitant
Simple Partial Seizures Hospitalization 2009 40 Female 5/23/2013 Physician De
Primary
Concomitant
Gait Disturbance Hospitalization 12/2010 Female 6/16/2013 Physician De
Primary
Concomitant
Weight Decreased Other Serious NotSpecified 2/22/2013 Other Health Professional De
Primary
Concomitant
Convulsion Other Serious 12/23/2012 70 Female 1/7/2013 Consumer Us
Primary
Concomitant
Limb Injury Hospitalization 47 Female 5/13/2013 Registered Nurse Us
Primary
Secondary
Concomitant
Epilepsy Hospitalization Female 5/6/2013 Physician De
Primary
Concomitant
Pregnancy Other Serious Female 3/27/2013 Physician Gb
Primary
Concomitant
Renal Failure Acute Hospitalization 9/13/2012 71 Female 128 lb 3/29/2013 Pharmacist Us
Primary
Concomitant
Convulsion Other Serious Male 10/31/2012 Us
Primary
Concomitant
Status Epilepticus Hospitalization 9 Male 60 lb 5/17/2013 Other Health Professional Country Not Specified
Primary
Secondary
Tremor Other Serious Male 9/25/2013 Physician Us
Primary
Concomitant
Drug Ineffective 0 Male 7/2/2013 Physician Es
Primary
Secondary
Sinus Arrhythmia Other Serious 49 Female 6/25/2013 Gb
Primary
Secondary
Muscle Spasms 9/24/2012 66 Female 167 lb 7/30/2013 Consumer Country Not Specified
Primary
Concomitant
Pneumonia Death 12/10/2012 3 Male 33 lb 8/2/2013 Pharmacist Us
Primary
Concomitant

Drug Data