Levetiracetam combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hemiparesis Hospitalization 3/13/2004 61 Female 128 lb 1/18/2006 Physician United States
Primary
Concomitant
Speech Disorder Life Threatening 2/1/2005 22 Male 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Disability 3/1/2006 43 220 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Cellulitis Required Intervention 11/17/2006 26 Female 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2005 Female 2/2/2007 Consumer United States
Primary
Concomitant
Sedation Other Serious 9/1/2006 46 Male 225 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/26/2006 63 Male 397 lb 11/8/2006 Pharmacist United States
Primary
Concomitant
Hepatitis Hospitalization 2/19/2007 72 Male 4/10/2007 United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/28/2007 48 Male 98 lb 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 2/19/2007 72 Male 5/16/2007 United Kingdom
Primary
Secondary
Concomitant
Confusional State Hospitalization 9/29/2006 51 Female 3/14/2007 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 87 Male 7/9/2007 Pharmacist United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 4/18/2004 31 Female 7/9/2007 United States
Primary
Concomitant
Convulsion Hospitalization 33 Female 7/25/2007 Physician United States
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 22 Female 8/8/2007 Physician Austria
Primary
Secondary
Concomitant
Mental Status Changes Postoperative Required Intervention 1/30/2007 38 Male 175 lb 5/15/2007 United States
Primary
Concomitant
Convulsion Hospitalization 33 Female 8/27/2007 Physician United States
Primary
Concomitant
Electroencephalogram Abnormal Other Serious 23 Female 9/6/2007 Belgium
Primary
Concomitant
Interacting
Electroencephalogram Abnormal Other Serious 41 Female 9/6/2007 Belgium
Primary
Concomitant
Interacting
Urine Ketone Body Present Death 36 Female 8/23/2007 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 36 Female 135 lb 9/13/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Life Threatening 46 Male 10/2/2007 Physician Czech Republic
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 4 Female 10/10/2007
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 13 Male 10/10/2007
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 1/1/2007 36 Female 10/17/2007 Physician United States
Primary
Secondary
Nephritis Interstitial Other Serious 40 Male 141 lb 10/27/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nephritis Interstitial Other Serious 40 Male 11/14/2007 Pharmacist United States
Primary
Secondary
Concomitant
Nephritis Interstitial 40 Male 141 lb 11/21/2007 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 8/30/2006 Female 11/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 11/15/2007 70 Female 12/17/2007 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 1/1/2008 37 Female 231 lb 2/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/10/2006 75 Female 2/19/2008 Physician Turkey
Primary
Secondary
Status Epilepticus Life Threatening 1/1/2008 37 Female 231 lb 2/19/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/18/2008 Male 99 lb 2/19/2008 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 56 Male 176 lb 3/5/2008 United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 3/4/2008 44 Male 154 lb 4/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/1/2007 37 Male 5/9/2008 Pharmacist United States
Primary
Secondary
Weight Increased Life Threatening 1/1/2002 Female 105 lb 5/30/2008 Consumer United States
Primary
Concomitant
Death Death 37 6/19/2008 Other Health Professional United States
Primary
Secondary
Hypotension Hospitalization 5/16/2008 78 Female 7/9/2008 Other Health Professional France
Primary
Concomitant
Vomiting Life Threatening 8/22/2002 68 Female 100 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 2/1/2008 52 Male 170 lb 7/21/2008 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization Female 7/15/2008 Other Health Professional Switzerland
Primary
Concomitant
Stress Hospitalization 37 Female 7/24/2008 Switzerland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Tracheo-oesophageal Fistula Congenital Anomaly 8/5/2008 Other Health Professional Ireland
Primary
Concomitant
Speech Disorder Developmental Hospitalization 1/1/2004 0 Male 15 lb 8/8/2008 Belgium
Primary
Secondary
Medication Residue 1/1/2007 Male 150 lb 9/2/2008 Physician United States
Primary
Concomitant
Splenic Infarction Hospitalization 52 Male 9/17/2008 United States
Primary
Secondary
Drug Toxicity Hospitalization 66 Male 9/24/2008 Australia
Primary
Concomitant
Somnolence Other Serious 7/26/2008 45 Male 9/25/2008 Other Health Professional United Kingdom
Primary
Interacting
Somnolence Other Serious 7/26/2008 45 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Interacting
Metabolic Acidosis Other Serious 59 Female 10/7/2008 United States
Primary
Concomitant
Convulsion Hospitalization 37 Female 10/21/2008 Other Health Professional Switzerland
Primary
Secondary
Neutropenia Hospitalization 8/26/2008 61 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
False Negative Laboratory Result Other Serious 47 Female 10/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Gastrostomy Tube Insertion Other Serious 9/23/2008 19 Male 11/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 6/1/2008 Female 110 lb 12/12/2008 United States
Primary
Concomitant
Drug Toxicity Death 37 12/18/2008 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/15/2008 61 Female 1/9/2009 Physician United Kingdom
Primary
Concomitant
Grand Mal Convulsion Other Serious 37 Male 176 lb 1/23/2009 Pharmacist Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/15/2008 61 Female 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/15/2008 61 Female 1/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/15/2008 61 Female 1/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 19 Male 1/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 12/15/2008 61 Female 2/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/14/2009 28 Male 3/6/2009 Consumer Switzerland
Primary
Concomitant
Weight Increased Female 3/12/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/3/2009 44 Female 110 lb 3/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 67 Female 4/10/2009 United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 1/14/2009 Male 5/1/2009 Consumer Switzerland
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 6 Male 5/7/2009 United States
Primary
Concomitant
Malabsorption Other Serious 41 Female 6/3/2009 Pharmacist France
Primary
Concomitant
Respiratory Distress Hospitalization Male 7 lb 6/5/2009 Physician Australia
Primary
Concomitant
Malabsorption Other Serious 41 Female 6/12/2009 Pharmacist France
Primary
Secondary
Embolic Cerebral Infarction Other Serious 6 Male 6/12/2009
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 32 Female 6/22/2009 Other Health Professional Greece
Primary
Secondary
Sepsis Death 72 Male 6/12/2009 Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 50 Male 6/25/2009 Pharmacist United States
Primary
Concomitant
Oedema Mouth 9/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Malabsorption Other Serious 41 Female 9/9/2009 Pharmacist France
Primary
Secondary
Ventricular Tachycardia Other Serious 2/24/2009 Female 9/23/2009 Consumer United States
Primary
Secondary
Ill-defined Disorder Other Serious 33 Female 9/25/2009 France
Primary
Concomitant
Mental Status Changes Required Intervention 5/27/2009 61 Female 192 lb 7/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Convulsion Other Serious 7/23/2009 31 Female 176 lb 10/6/2009 Other Health Professional Switzerland
Primary
Concomitant
Ill-defined Disorder Other Serious 33 Female 10/6/2009 France
Primary
Concomitant
Viral Upper Respiratory Tract Infection Required Intervention 21 Female 128 lb 10/6/2009 Switzerland
Primary
Concomitant
Rash Pruritic Hospitalization 52 Male 9/18/2009 Other Health Professional United States
Primary
Secondary
Tremor Hospitalization 9/13/2009 39 Female 9/14/2009 Pharmacist United States
Primary
Concomitant
Confusional State Hospitalization 11/25/2008 48 Male 9/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/24/2009 Female 11/11/2009 Physician United States
Primary
Secondary
Drug Ineffective Other Serious 75 Female 11/5/2009 Spain
Primary
Concomitant
Drug Ineffective Other Serious 11 Female 11/5/2009 Physician Spain
Primary
Concomitant
Drug Ineffective Other Serious 23 Female 11/5/2009 Spain
Primary
Concomitant
Drug Ineffective Other Serious 62 Female 11/5/2009 Spain
Primary
Concomitant
Drug Ineffective Death 74 Male 11/5/2009 Spain
Primary
Concomitant
Drug Ineffective Death 64 Male 11/5/2009 Spain
Primary
Concomitant
Drug Ineffective Death 83 Male 11/5/2009 Spain
Primary
Concomitant
Memory Impairment Other Serious 32 Male 12/14/2009 Other Health Professional United States
Primary
Concomitant
Hyperammonaemic Encephalopathy Other Serious 53 Female 1/1/2010 Other Health Professional United States
Primary
Secondary
Hyperammonaemic Encephalopathy Other Serious 53 Female 1/6/2010 Other Health Professional United States
Primary
Secondary
Status Epilepticus Other Serious 53 Female 1/22/2010
Primary
Secondary
Concomitant
Sweat Gland Disorder Other Serious 9 Male 1/18/2010 United Kingdom
Primary
Secondary
Concomitant
Urticaria 8/1/2009 Female 1/30/2010 United States
Primary
Concomitant
Metabolic Disorder Hospitalization 53 Female 1/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 9/24/2008 50 Male 149 lb 2/10/2010 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Other Serious 37 Female 1/26/2010 United States
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 53 Female 2/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 40 Male 141 lb 3/18/2010 Pharmacist United States
Primary
Concomitant
Eosinophilia Life Threatening 1/11/2010 Female 132 lb 3/29/2010 Other Health Professional Germany
Primary
Secondary
Metabolic Acidosis Other Serious 9 Female 4/7/2010 Physician United States
Primary
Concomitant
Hypotension Hospitalization 2/19/2010 28 Female 119 lb 4/15/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 4/3/2010 57 Male 114 lb 4/16/2010 Physician Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 9 Female 4/26/2010
Primary
Secondary
Concomitant
Urticaria Other Serious 71 Female 4/28/2010 Austria
Primary
Concomitant
Hyperhidrosis Other Serious 51 Male 4/27/2010 Austria
Primary
Concomitant
Respiratory Distress Hospitalization Male 7 lb 5/10/2010 Physician Sweden
Primary
Concomitant
Pneumonia Mycoplasmal Hospitalization 2/18/2010 40 Female 102 lb 5/4/2010 Other Health Professional Japan
Primary
Concomitant
Eosinophilia Life Threatening 1/11/2010 57 Female 132 lb 5/6/2010 Other Health Professional Germany
Primary
Secondary
Metabolic Acidosis Hospitalization 9 Female 5/8/2010 Physician United States
Primary
Concomitant
Hypocalcaemia Hospitalization 57 Male 5/17/2010 Physician United States
Primary
Concomitant
Status Epilepticus Life Threatening 4/7/2010 25 Female 110 lb 5/26/2010 Physician Japan
Primary
Concomitant
Convulsion Required Intervention 1/1/2010 57 Male 210 lb 5/29/2010 United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 73 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Hypotension Hospitalization 2/19/2010 28 Female 119 lb 6/14/2010 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 46 Female 6/11/2010 Other Health Professional United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 57 Male 6/18/2010 Physician United States
Primary
Concomitant
Product Substitution Issue Other Serious 5/1/2010 37 Female 6/1/2010 Physician United States
Primary
Secondary
Granulocytopenia Other Serious 4/12/2010 25 Male 143 lb 6/24/2010 Pharmacist United States
Primary
Concomitant

Drug Data